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The map label for this gene is hbpA [H]

Identifier: 221633925

GI number: 221633925

Start: 1970121

End: 1971965

Strand: Reverse

Name: hbpA [H]

Synonym: trd_1952

Alternate gene names: 221633925

Gene position: 1971965-1970121 (Counterclockwise)

Preceding gene: 221633928

Following gene: 221633924

Centisome position: 98.45

GC content: 59.57

Gene sequence:

>1845_bases
ATGGATAACCCATTGACGCAGCGGACGTCTCGCCGCGCCTTTCTCGGTCGCCTCGTTGGTGTCGCTGGAGTCTCGGCTCT
GCTTGCCGCGTGTCGCGCTCCCCGTGCCCCCACCCCGGCACCGGGTCAGACCCCGGTTGCCGCGGTGACGCCAACCGTCC
CTGGTCCTACTCCGATCCCCGGCCAGATACCTGCCAAACCACGCAACCGCACCCTGATCCTCCGCTGGGGCGGACAAGAG
GGACGGCACGTCGACTGGGAACTCTGGAACGGCTACGCTATTGGCGCCAATCACCAGAATGGGCTTGGCATCCTCTACGA
GCCGCTCGCGTATTACTCGGCGTTCGCCGACAAGTGGTACCCCTGGTTGGCCGAGGACTGGCAGTATAGCGGCGATTTTA
AGGAACTCACCATCAAGACGCGCTCTGGCATCACATGGAGCGATGGCAAACCCTTCACCGCTCACGATGTCGCCTTCACG
CTCAATAGTCTTCGTGATCTTGGAACCAAGGTACGATGGGGCGTCGACGTTCAGCAGTTCGTTCAGGAGGCGGTGGCCGA
GAGCGACACGCTCGTGCGGGTGAAGTTCAAGGTACCCGCTCCGCGCTTCTTCTACTTTATGACCTACAAGTTCGACATCG
GCGTCTACATCGTCCCGAAGCATATCTATGAGAATCAAGATTGGACCACCTTTACCGCGTTCGACCCCGAGCGCGGCTGG
CCAGTCACCACCAGTCCGTGGCGGGTCGTTTTCTCTTCGCCGGAGCAGAAGGTCATCGACCTGCGTGACGACGAGTGGTG
GGCAGTGCGCGCTGGGCTCGTCAAGGCGAAGCCACGCGTCCAGCGGGTCGTCTACCTTCCATTCACGCTCGAGGAGCAGG
TCGCGCAGCAGATCATCGCCAACGAGGTCGACTGCTCCCTCGACCTCCGGCCGCTCACGATGAAGACCGTGCTCCAGCAG
AATCCGAAAGTGATCACCCACACCTACAAGGATCCTCCCTATGGCTACGAAGATTGGTGGCCGACTTCGCTGTATGTCAA
CTGCGAGCGTGCGCCATACAACGATAAGGATGTCCGCTGGGCACTCAGCTACTTCATCGATCGCAAGACGTTGATCGAGG
TTGCGCTGGGTGGGGCGGGGGAGCCGACCGAGCTTCCGCTGCCACACTACACTGGTCTTCTTCCATTCTTCGACGCTGTC
CGTGATCTGCTGCAGCAGTATCCGACCAATGAGTTCAATCCTCAGAAGGGAAATCAGCTCCTCGAGGGCAAGGGGTGGCG
CAAGAACGCCGAGGGCTTTTGGGAGAAGGATGGCAAGGTCCTTGAGGTACCGATAGAGAGCTTTGCCGTCATGGCTGATA
TCGGCCCGGTGATTGCCGAAATGCTGCGTCGCCAAGGAGTGCGTTCTTCGTACGCCATGCCGCCGGACTTCTTTGACCGC
TTCGGGAAAGGGGATTACAATGCCTCGCTCTTCGGGCACGGAGGCAGCATCGGGCTCGATCCGTACTTCACCCTGCGCCT
GTACCAGTCGGTGACCGAGGCTGTCCCGGGCGGCCATCAGGTGAACTTTTCACGGTGGAAGAATTCCCAGTTCGACAAGA
TCGTCGACGAAATGGCTGTCACACCACCGGAGCAACGCGACAAAATTATGGACCAGTGGCGGCGGGCCATGGAGATCTGG
TTGCCTGAGTTGCCGGACATTCCGATCCAGAAGTGGTTCCATCGCATTCCGATGAATACGACCTACTGGCAAAACTGGCC
CACGCGCGACAATCCGTATGTCAATGGCGCTTTCTGGCACCTGACGTTCCAGCTCATTCTCAACGAACTCGAGCCGACAC
AATGA

Upstream 100 bases:

>100_bases
TATGAGGGTACCAATGTGCTGTAGGCAATGACAAGCTCGTTTTCTCCGCCCTCTAGTGTCTGGCGACGAGCGGTCGGATG
CTTCGAGGAGGAGGACCGCG

Downstream 100 bases:

>100_bases
GACGATTTCGCATCGCGCTGAGGACGAGCAGCTGCGCGGCTTGCTGCCCAGCGCGGTGTCCAATTGTTTTCTGAGGTACG
GAGCTGGTCACAAGGCTGGA

Product: extracellular solute-binding protein

Products: Ni2; [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 614; Mature: 614

Protein sequence:

>614_residues
MDNPLTQRTSRRAFLGRLVGVAGVSALLAACRAPRAPTPAPGQTPVAAVTPTVPGPTPIPGQIPAKPRNRTLILRWGGQE
GRHVDWELWNGYAIGANHQNGLGILYEPLAYYSAFADKWYPWLAEDWQYSGDFKELTIKTRSGITWSDGKPFTAHDVAFT
LNSLRDLGTKVRWGVDVQQFVQEAVAESDTLVRVKFKVPAPRFFYFMTYKFDIGVYIVPKHIYENQDWTTFTAFDPERGW
PVTTSPWRVVFSSPEQKVIDLRDDEWWAVRAGLVKAKPRVQRVVYLPFTLEEQVAQQIIANEVDCSLDLRPLTMKTVLQQ
NPKVITHTYKDPPYGYEDWWPTSLYVNCERAPYNDKDVRWALSYFIDRKTLIEVALGGAGEPTELPLPHYTGLLPFFDAV
RDLLQQYPTNEFNPQKGNQLLEGKGWRKNAEGFWEKDGKVLEVPIESFAVMADIGPVIAEMLRRQGVRSSYAMPPDFFDR
FGKGDYNASLFGHGGSIGLDPYFTLRLYQSVTEAVPGGHQVNFSRWKNSQFDKIVDEMAVTPPEQRDKIMDQWRRAMEIW
LPELPDIPIQKWFHRIPMNTTYWQNWPTRDNPYVNGAFWHLTFQLILNELEPTQ

Sequences:

>Translated_614_residues
MDNPLTQRTSRRAFLGRLVGVAGVSALLAACRAPRAPTPAPGQTPVAAVTPTVPGPTPIPGQIPAKPRNRTLILRWGGQE
GRHVDWELWNGYAIGANHQNGLGILYEPLAYYSAFADKWYPWLAEDWQYSGDFKELTIKTRSGITWSDGKPFTAHDVAFT
LNSLRDLGTKVRWGVDVQQFVQEAVAESDTLVRVKFKVPAPRFFYFMTYKFDIGVYIVPKHIYENQDWTTFTAFDPERGW
PVTTSPWRVVFSSPEQKVIDLRDDEWWAVRAGLVKAKPRVQRVVYLPFTLEEQVAQQIIANEVDCSLDLRPLTMKTVLQQ
NPKVITHTYKDPPYGYEDWWPTSLYVNCERAPYNDKDVRWALSYFIDRKTLIEVALGGAGEPTELPLPHYTGLLPFFDAV
RDLLQQYPTNEFNPQKGNQLLEGKGWRKNAEGFWEKDGKVLEVPIESFAVMADIGPVIAEMLRRQGVRSSYAMPPDFFDR
FGKGDYNASLFGHGGSIGLDPYFTLRLYQSVTEAVPGGHQVNFSRWKNSQFDKIVDEMAVTPPEQRDKIMDQWRRAMEIW
LPELPDIPIQKWFHRIPMNTTYWQNWPTRDNPYVNGAFWHLTFQLILNELEPTQ
>Mature_614_residues
MDNPLTQRTSRRAFLGRLVGVAGVSALLAACRAPRAPTPAPGQTPVAAVTPTVPGPTPIPGQIPAKPRNRTLILRWGGQE
GRHVDWELWNGYAIGANHQNGLGILYEPLAYYSAFADKWYPWLAEDWQYSGDFKELTIKTRSGITWSDGKPFTAHDVAFT
LNSLRDLGTKVRWGVDVQQFVQEAVAESDTLVRVKFKVPAPRFFYFMTYKFDIGVYIVPKHIYENQDWTTFTAFDPERGW
PVTTSPWRVVFSSPEQKVIDLRDDEWWAVRAGLVKAKPRVQRVVYLPFTLEEQVAQQIIANEVDCSLDLRPLTMKTVLQQ
NPKVITHTYKDPPYGYEDWWPTSLYVNCERAPYNDKDVRWALSYFIDRKTLIEVALGGAGEPTELPLPHYTGLLPFFDAV
RDLLQQYPTNEFNPQKGNQLLEGKGWRKNAEGFWEKDGKVLEVPIESFAVMADIGPVIAEMLRRQGVRSSYAMPPDFFDR
FGKGDYNASLFGHGGSIGLDPYFTLRLYQSVTEAVPGGHQVNFSRWKNSQFDKIVDEMAVTPPEQRDKIMDQWRRAMEIW
LPELPDIPIQKWFHRIPMNTTYWQNWPTRDNPYVNGAFWHLTFQLILNELEPTQ

Specific function: Important role in heme acquisition or metabolism [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789887, Length=382, Percent_Identity=25.3926701570681, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 70470; Mature: 70470

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNPLTQRTSRRAFLGRLVGVAGVSALLAACRAPRAPTPAPGQTPVAAVTPTVPGPTPIP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCC
GQIPAKPRNRTLILRWGGQEGRHVDWELWNGYAIGANHQNGLGILYEPLAYYSAFADKWY
CCCCCCCCCCEEEEEECCCCCCEEEEEEECCEEECCCCCCCCCEEEHHHHHHHHHHHHCC
PWLAEDWQYSGDFKELTIKTRSGITWSDGKPFTAHDVAFTLNSLRDLGTKVRWGVDVQQF
CCCCCCCCCCCCCEEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEECCCHHHH
VQEAVAESDTLVRVKFKVPAPRFFYFMTYKFDIGVYIVPKHIYENQDWTTFTAFDPERGW
HHHHHCCCCCEEEEEEECCCCEEEEEEEEEEEEEEEEEEHHHCCCCCCEEEEEECCCCCC
PVTTSPWRVVFSSPEQKVIDLRDDEWWAVRAGLVKAKPRVQRVVYLPFTLEEQVAQQIIA
CCCCCCCEEEECCCCCEEEECCCCCEEEEECCHHHCCCCEEEEEEECCCHHHHHHHHHHH
NEVDCSLDLRPLTMKTVLQQNPKVITHTYKDPPYGYEDWWPTSLYVNCERAPYNDKDVRW
CCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCHHHHH
ALSYFIDRKTLIEVALGGAGEPTELPLPHYTGLLPFFDAVRDLLQQYPTNEFNPQKGNQL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
LEGKGWRKNAEGFWEKDGKVLEVPIESFAVMADIGPVIAEMLRRQGVRSSYAMPPDFFDR
CCCCCCCCCCCCHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
FGKGDYNASLFGHGGSIGLDPYFTLRLYQSVTEAVPGGHQVNFSRWKNSQFDKIVDEMAV
CCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHCCCCHHHHHHHHHCC
TPPEQRDKIMDQWRRAMEIWLPELPDIPIQKWFHRIPMNTTYWQNWPTRDNPYVNGAFWH
CCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEECCCHHH
LTFQLILNELEPTQ
HHHHHHHHHCCCCC
>Mature Secondary Structure
MDNPLTQRTSRRAFLGRLVGVAGVSALLAACRAPRAPTPAPGQTPVAAVTPTVPGPTPIP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCC
GQIPAKPRNRTLILRWGGQEGRHVDWELWNGYAIGANHQNGLGILYEPLAYYSAFADKWY
CCCCCCCCCCEEEEEECCCCCCEEEEEEECCEEECCCCCCCCCEEEHHHHHHHHHHHHCC
PWLAEDWQYSGDFKELTIKTRSGITWSDGKPFTAHDVAFTLNSLRDLGTKVRWGVDVQQF
CCCCCCCCCCCCCEEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEECCCHHHH
VQEAVAESDTLVRVKFKVPAPRFFYFMTYKFDIGVYIVPKHIYENQDWTTFTAFDPERGW
HHHHHCCCCCEEEEEEECCCCEEEEEEEEEEEEEEEEEEHHHCCCCCCEEEEEECCCCCC
PVTTSPWRVVFSSPEQKVIDLRDDEWWAVRAGLVKAKPRVQRVVYLPFTLEEQVAQQIIA
CCCCCCCEEEECCCCCEEEECCCCCEEEEECCHHHCCCCEEEEEEECCCHHHHHHHHHHH
NEVDCSLDLRPLTMKTVLQQNPKVITHTYKDPPYGYEDWWPTSLYVNCERAPYNDKDVRW
CCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCHHHHH
ALSYFIDRKTLIEVALGGAGEPTELPLPHYTGLLPFFDAVRDLLQQYPTNEFNPQKGNQL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
LEGKGWRKNAEGFWEKDGKVLEVPIESFAVMADIGPVIAEMLRRQGVRSSYAMPPDFFDR
CCCCCCCCCCCCHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
FGKGDYNASLFGHGGSIGLDPYFTLRLYQSVTEAVPGGHQVNFSRWKNSQFDKIVDEMAV
CCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHCCCCHHHHHHHHHCC
TPPEQRDKIMDQWRRAMEIWLPELPDIPIQKWFHRIPMNTTYWQNWPTRDNPYVNGAFWH
CCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEECCCHHH
LTFQLILNELEPTQ
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; ATP; H2O [C]

Specific reaction: Ni2+ [Periplasm] + ATP + H2O = Ni2+ [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]