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The map label for this gene is appC [H]

Identifier: 221633923

GI number: 221633923

Start: 1968161

End: 1969000

Strand: Reverse

Name: appC [H]

Synonym: trd_1950

Alternate gene names: 221633923

Gene position: 1969000-1968161 (Counterclockwise)

Preceding gene: 221633924

Following gene: 221633922

Centisome position: 98.3

GC content: 61.19

Gene sequence:

>840_bases
ATGTGGGCATACCTCCGTCGTAATCCGAGCCTCTTGGTCGGTCTCATCTTGCTCGGCATCGTCCTCGCCTTCGCCGGCAT
CGGCCGTCTCGTTTGGGATACATCCATGGCCGCTCCTCTTTCCTCCATGCCGAACCAGGGCCCCTCTTGGGAGCATCCTT
TAGGAACCGACCGTCAAGGCCGCGATATCTTGGCAGTGATGATCGTCGGAACCCCCCTCACCCTCTACATAGGGGTTCTC
GCTGGCCTGCTCGGTGTCATCGTGGGCACGATCCTTGCCCTCCTCTCAGGCTACTTCGGTGGGATCATCGATAGTATCGT
CCGCGGCATCGTCGATGTGGGGCTCACGATCCCGCCGCTACTCGTCCTGATCCTGGTTGCCGTCTCAGTTCGGGCAAATC
TCTCGATTTCCCAGATGGCTCTCGTCGTTGCCTCGCTCGCGTGGCTCTGGCCGGCACGAACGATCCGTTCTCAGGTCCTC
ACGCTGCGTGAGCGGGCCTGGGTCCAAGTTGCCCGCTTGTCCGGGGCCAGCCACTCGCAGATCCTCTTCTTCGAGGTCCT
TCCTAACCTGCTTCCGTATCTCATGGCCACCTTCGTCGGGGCCGTGGCCTCCGCCATTCTCGCCTCCATCGGCCTGGAGG
TCATCGGACTCGGTCCGATGGAGGCGAACACGCTGGGGATGACGATCTATTGGGTCAGCTATTACGCTGCCCTGCTGCAT
GGAATGTGGTGGTGGTTTTTGCCACCCATCGTGATCATCATCGCGATTTTCGTCAGCCTCTTCGCCATTTCGGCCGGGCT
TGACGAGTTCGCCAACCCGCGGCGTCGCCGAGCGGTGTAG

Upstream 100 bases:

>100_bases
ACAGTTGTTCTCGGAGTTACGTTCGCCACCTTTATCCTCGATCTTCTTTATCCTCTGATCGACCCCCGTATCACCTATCA
GGCGCGGTAAAGGAGGTCTT

Downstream 100 bases:

>100_bases
CCCACGGCCCCAGCAGCCCTCGTCCCAGAGGAGCCACCGGAGTAGCACTCGCTGCGACCTCCCCATCATGGACGAGCAGC
CGCTGGACCATCGCGCGCGA

Product: maltose ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MWAYLRRNPSLLVGLILLGIVLAFAGIGRLVWDTSMAAPLSSMPNQGPSWEHPLGTDRQGRDILAVMIVGTPLTLYIGVL
AGLLGVIVGTILALLSGYFGGIIDSIVRGIVDVGLTIPPLLVLILVAVSVRANLSISQMALVVASLAWLWPARTIRSQVL
TLRERAWVQVARLSGASHSQILFFEVLPNLLPYLMATFVGAVASAILASIGLEVIGLGPMEANTLGMTIYWVSYYAALLH
GMWWWFLPPIVIIIAIFVSLFAISAGLDEFANPRRRRAV

Sequences:

>Translated_279_residues
MWAYLRRNPSLLVGLILLGIVLAFAGIGRLVWDTSMAAPLSSMPNQGPSWEHPLGTDRQGRDILAVMIVGTPLTLYIGVL
AGLLGVIVGTILALLSGYFGGIIDSIVRGIVDVGLTIPPLLVLILVAVSVRANLSISQMALVVASLAWLWPARTIRSQVL
TLRERAWVQVARLSGASHSQILFFEVLPNLLPYLMATFVGAVASAILASIGLEVIGLGPMEANTLGMTIYWVSYYAALLH
GMWWWFLPPIVIIIAIFVSLFAISAGLDEFANPRRRRAV
>Mature_279_residues
MWAYLRRNPSLLVGLILLGIVLAFAGIGRLVWDTSMAAPLSSMPNQGPSWEHPLGTDRQGRDILAVMIVGTPLTLYIGVL
AGLLGVIVGTILALLSGYFGGIIDSIVRGIVDVGLTIPPLLVLILVAVSVRANLSISQMALVVASLAWLWPARTIRSQVL
TLRERAWVQVARLSGASHSQILFFEVLPNLLPYLMATFVGAVASAILASIGLEVIGLGPMEANTLGMTIYWVSYYAALLH
GMWWWFLPPIVIIIAIFVSLFAISAGLDEFANPRRRRAV

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=174, Percent_Identity=31.6091954022989, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787760, Length=230, Percent_Identity=27.8260869565217, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789964, Length=236, Percent_Identity=28.8135593220339, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787498, Length=292, Percent_Identity=27.7397260273973, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787549, Length=177, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788505, Length=180, Percent_Identity=26.1111111111111, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789889, Length=172, Percent_Identity=29.0697674418605, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30150; Mature: 30150

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWAYLRRNPSLLVGLILLGIVLAFAGIGRLVWDTSMAAPLSSMPNQGPSWEHPLGTDRQG
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCC
RDILAVMIVGTPLTLYIGVLAGLLGVIVGTILALLSGYFGGIIDSIVRGIVDVGLTIPPL
CCEEEHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LVLILVAVSVRANLSISQMALVVASLAWLWPARTIRSQVLTLRERAWVQVARLSGASHSQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
ILFFEVLPNLLPYLMATFVGAVASAILASIGLEVIGLGPMEANTLGMTIYWVSYYAALLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEECCCCCCCHHHHHHHHHHHHHHHHH
GMWWWFLPPIVIIIAIFVSLFAISAGLDEFANPRRRRAV
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHCCC
>Mature Secondary Structure
MWAYLRRNPSLLVGLILLGIVLAFAGIGRLVWDTSMAAPLSSMPNQGPSWEHPLGTDRQG
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCC
RDILAVMIVGTPLTLYIGVLAGLLGVIVGTILALLSGYFGGIIDSIVRGIVDVGLTIPPL
CCEEEHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LVLILVAVSVRANLSISQMALVVASLAWLWPARTIRSQVLTLRERAWVQVARLSGASHSQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
ILFFEVLPNLLPYLMATFVGAVASAILASIGLEVIGLGPMEANTLGMTIYWVSYYAALLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEECCCCCCCHHHHHHHHHHHHHHHHH
GMWWWFLPPIVIIIAIFVSLFAISAGLDEFANPRRRRAV
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]