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The map label for this gene is yycF [H]

Identifier: 221633806

GI number: 221633806

Start: 1843196

End: 1843957

Strand: Reverse

Name: yycF [H]

Synonym: trd_1833

Alternate gene names: 221633806

Gene position: 1843957-1843196 (Counterclockwise)

Preceding gene: 221633807

Following gene: 221633805

Centisome position: 92.06

GC content: 64.17

Gene sequence:

>762_bases
ATGGTCACGGTGAGCAGTCGATCGACCACGCGACCAGAAGGAACACCGACGCAGCAGCGTATCCTGATCGTCGAGGATGA
TCCGACACTCGCCCAGATTCTCTCCTACAGCCTGGAACAACGCGGCTACAGCGTCTGGACCGCCCAAGAGGGCCGGCACG
CGATCATGCTGGCGCGCACCATCCGACCCGACCTCATCATCCTCGATCTGATGCTCCCGGGTATCGACGGGCGCGATGTC
TGCCGGCTGATCCGCAAGTGGTCGAGCGCGCCCATCCTCGTGTTGACGGCCCGCGACAGCGAAGACGACATCGTCGCGCT
GTTCCAGGAAGGCGCCGACGATTACGTGGTGAAGCCCTTCCGCACGCGCGAACTCTTTGCCCGGATCGACGCCTTGCTGC
GCCGGTCGGCAGAGACGACAGCCGGAAACGTGCTCACGGCCGGAACGCTCGTGATCTTCCGCGACGAGCACCGCGTGGTG
TACCGGGGACGGGAGGTTCATCTCGCGCCGCGTGAGTTCGCCCTGCTCACCGCACTGGTCGAGCGGGCCGGTCGCGTGTG
CACGCGGCAGGAGCTTCTCGACCTGGTCTGGGGACAGGACGTCGTCGACCTCCGGAACGTCGATGTCCACATCCACCGGA
TCCGGGAAGCACTGGGAGGAGAGCCAGATGGGTCGAACCTGATCAGAACGGTCCACGGAATCGGATACCGGTTCGTACCG
GAATTGGCGGCAATGGACGAGACGAATGGAGGAGGAAGTTGA

Upstream 100 bases:

>100_bases
CGCGTCGTCAGCGAACTCGCCCCGTTAATCGACCGTTAATCTCCCGCTGATCCTCCGTTAATCGCAGCCCGGTACACTGC
CCACAGTGAAGGGAAGACGG

Downstream 100 bases:

>100_bases
CCATGCAGGAACGGACGACGCGACTGAGTCGACGGCAATTGATCGCGCGCCTGGCCACACTGGGCGCCACGGTTCCGGTA
GCGAGCGCGCTCATCGCAGC

Product: phosphate regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MVTVSSRSTTRPEGTPTQQRILIVEDDPTLAQILSYSLEQRGYSVWTAQEGRHAIMLARTIRPDLIILDLMLPGIDGRDV
CRLIRKWSSAPILVLTARDSEDDIVALFQEGADDYVVKPFRTRELFARIDALLRRSAETTAGNVLTAGTLVIFRDEHRVV
YRGREVHLAPREFALLTALVERAGRVCTRQELLDLVWGQDVVDLRNVDVHIHRIREALGGEPDGSNLIRTVHGIGYRFVP
ELAAMDETNGGGS

Sequences:

>Translated_253_residues
MVTVSSRSTTRPEGTPTQQRILIVEDDPTLAQILSYSLEQRGYSVWTAQEGRHAIMLARTIRPDLIILDLMLPGIDGRDV
CRLIRKWSSAPILVLTARDSEDDIVALFQEGADDYVVKPFRTRELFARIDALLRRSAETTAGNVLTAGTLVIFRDEHRVV
YRGREVHLAPREFALLTALVERAGRVCTRQELLDLVWGQDVVDLRNVDVHIHRIREALGGEPDGSNLIRTVHGIGYRFVP
ELAAMDETNGGGS
>Mature_253_residues
MVTVSSRSTTRPEGTPTQQRILIVEDDPTLAQILSYSLEQRGYSVWTAQEGRHAIMLARTIRPDLIILDLMLPGIDGRDV
CRLIRKWSSAPILVLTARDSEDDIVALFQEGADDYVVKPFRTRELFARIDALLRRSAETTAGNVLTAGTLVIFRDEHRVV
YRGREVHLAPREFALLTALVERAGRVCTRQELLDLVWGQDVVDLRNVDVHIHRIREALGGEPDGSNLIRTVHGIGYRFVP
ELAAMDETNGGGS

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=41.1764705882353, Blast_Score=153, Evalue=9e-39,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=39.1111111111111, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=38.5964912280702, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=39.5454545454545, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=38.3928571428571, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=35.4430379746835, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=36.1990950226244, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=38.2882882882883, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=35.1111111111111, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=36.2445414847162, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=33.1914893617021, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=32.5892857142857, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=31.858407079646, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=32.1888412017167, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788905, Length=121, Percent_Identity=35.5371900826446, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=27.9279279279279, Blast_Score=61, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=109, Percent_Identity=29.3577981651376, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28306; Mature: 28306

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTVSSRSTTRPEGTPTQQRILIVEDDPTLAQILSYSLEQRGYSVWTAQEGRHAIMLART
CEEECCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCEEEEEEEC
IRPDLIILDLMLPGIDGRDVCRLIRKWSSAPILVLTARDSEDDIVALFQEGADDYVVKPF
CCCCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHEECCCCCCEEECCH
RTRELFARIDALLRRSAETTAGNVLTAGTLVIFRDEHRVVYRGREVHLAPREFALLTALV
HHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCEEEEECCEEEECHHHHHHHHHHH
ERAGRVCTRQELLDLVWGQDVVDLRNVDVHIHRIREALGGEPDGSNLIRTVHGIGYRFVP
HHHCCHHHHHHHHHHHCCCCCEEHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHH
ELAAMDETNGGGS
HHHHCCCCCCCCC
>Mature Secondary Structure
MVTVSSRSTTRPEGTPTQQRILIVEDDPTLAQILSYSLEQRGYSVWTAQEGRHAIMLART
CEEECCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCEEEEEEEC
IRPDLIILDLMLPGIDGRDVCRLIRKWSSAPILVLTARDSEDDIVALFQEGADDYVVKPF
CCCCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHEECCCCCCEEECCH
RTRELFARIDALLRRSAETTAGNVLTAGTLVIFRDEHRVVYRGREVHLAPREFALLTALV
HHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCEEEEECCEEEECHHHHHHHHHHH
ERAGRVCTRQELLDLVWGQDVVDLRNVDVHIHRIREALGGEPDGSNLIRTVHGIGYRFVP
HHHCCHHHHHHHHHHHCCCCCEEHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHH
ELAAMDETNGGGS
HHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]