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The map label for this gene is sucC [H]

Identifier: 221633777

GI number: 221633777

Start: 1808352

End: 1809524

Strand: Reverse

Name: sucC [H]

Synonym: trd_1804

Alternate gene names: 221633777

Gene position: 1809524-1808352 (Counterclockwise)

Preceding gene: 221633782

Following gene: 221633776

Centisome position: 90.34

GC content: 64.79

Gene sequence:

>1173_bases
ATGATCGGCGCGGTAGTCGAGTCGGAAGGCGGGGCGATGGATCTCCACGAATATCAAGCAGCAGAACTTTTTGCACGGTA
TGGGATTCCGGTCAACCGTGGGATCGTGGCCCGGACTCCAGAGGAAGCCAGCGCTGCAGCCGAACAGTTGGGCGGCCGGG
TCGTGGTGAAAGCGCAGGTCCACGCCGGAGGTCGCGGCAAAGCCGGTGGAATCCGCCTGGCCGATGATCCAGTCCAGGCC
GAGGCTGTTGCCCGGCAGATCCTCGGTATGGAGATTCGCGGGCGGATCGTCCGCAAAGTGCTGGTTGCGCCAGCAGTCGC
CTTCGAGCGGGAGTATTACCTGGGGGCTGTGCTCGATCGCGATAGTCGTCGCATCGTGGTGATGGCGAGCAGCGCGGGCG
GTGTCGATATCGAGGAAGTCGCCCGCGAACGCCCGACCGCGATCGTCCGCGAGCAGGCTGATCCCTTCCTCGGTTTCCTC
GACTTCCAGGCGCGGCGGCTCGCCTTCCGGCTCGGCATCGAACCGGACCTGGTGCGGGGTTTCGCGACGATCGCTCGGCA
ACTCTACCGCGCTTTCGTCGACAACGATGCTTCGCTGGCGGAGATCAATCCGCTGGTCCTCACACAGGATCGCTCCTGGC
TCGCCCTCGATACCAAGGTCGTGCTCGACGACAACGGATTGTTCCGGCATCCGGATCTGGCCGAACTCCGCGACCCCGAG
GAGGAAGACCCGCTGGAGCGGGAAGCCCGGCTGGCAGGGATCAGCTTCGTGCGCCTGAACGGGACCGTCGGGTGCATCGT
CAATGGAGCAGGGCTCTCCATGGCGACGATGGACGCCATCAAACTGTACGGTGGGGAGCCAGCGAATTTCCTGGACATCG
GTGGAGGAGCCTCGGCGCAGCGGGTGGCGGCGGCTTTGCGGATCGTCGTCGCTGATCCCAACGTCCGCGCCATTCTGGTC
AATATCTTCGGGGGCATCACGCGCGGCGATGTGGTGGCACAAGGGATTCTCGAGGCCCTGCGCCAAGTCGAGGTTCGCGT
GCCGATGGTGATCCGTCTCGTCGGAACGCGCCAGGAGGAGGGGCGTCGCCTGCTCGAGGAAGCTGGTTTCACGGTCGTGG
ACACGATGGAAGAAGCAGCGCAGCGAGCCGTGGCACTCGCGCAAGGTCAGTGA

Upstream 100 bases:

>100_bases
GCCATGACAGCCGAGCGAGGGAGTACGGATCGGCACCAGGGGGCGAGACCACCTTTTCAGTCATGGCGAACGCGCGCCGA
AAACGGTGACGCCACGTGGT

Downstream 100 bases:

>100_bases
GGCGGGGGCGGGAGATGGCGATCCTGGTCGACGAGTCGACGCGGTTGCTGGTGCAAGGAATCACCGGGAAGGAAGGCTCG
TTCCACACCGGGCAGATGAT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MIGAVVESEGGAMDLHEYQAAELFARYGIPVNRGIVARTPEEASAAAEQLGGRVVVKAQVHAGGRGKAGGIRLADDPVQA
EAVARQILGMEIRGRIVRKVLVAPAVAFEREYYLGAVLDRDSRRIVVMASSAGGVDIEEVARERPTAIVREQADPFLGFL
DFQARRLAFRLGIEPDLVRGFATIARQLYRAFVDNDASLAEINPLVLTQDRSWLALDTKVVLDDNGLFRHPDLAELRDPE
EEDPLEREARLAGISFVRLNGTVGCIVNGAGLSMATMDAIKLYGGEPANFLDIGGGASAQRVAAALRIVVADPNVRAILV
NIFGGITRGDVVAQGILEALRQVEVRVPMVIRLVGTRQEEGRRLLEEAGFTVVDTMEEAAQRAVALAQGQ

Sequences:

>Translated_390_residues
MIGAVVESEGGAMDLHEYQAAELFARYGIPVNRGIVARTPEEASAAAEQLGGRVVVKAQVHAGGRGKAGGIRLADDPVQA
EAVARQILGMEIRGRIVRKVLVAPAVAFEREYYLGAVLDRDSRRIVVMASSAGGVDIEEVARERPTAIVREQADPFLGFL
DFQARRLAFRLGIEPDLVRGFATIARQLYRAFVDNDASLAEINPLVLTQDRSWLALDTKVVLDDNGLFRHPDLAELRDPE
EEDPLEREARLAGISFVRLNGTVGCIVNGAGLSMATMDAIKLYGGEPANFLDIGGGASAQRVAAALRIVVADPNVRAILV
NIFGGITRGDVVAQGILEALRQVEVRVPMVIRLVGTRQEEGRRLLEEAGFTVVDTMEEAAQRAVALAQGQ
>Mature_390_residues
MIGAVVESEGGAMDLHEYQAAELFARYGIPVNRGIVARTPEEASAAAEQLGGRVVVKAQVHAGGRGKAGGIRLADDPVQA
EAVARQILGMEIRGRIVRKVLVAPAVAFEREYYLGAVLDRDSRRIVVMASSAGGVDIEEVARERPTAIVREQADPFLGFL
DFQARRLAFRLGIEPDLVRGFATIARQLYRAFVDNDASLAEINPLVLTQDRSWLALDTKVVLDDNGLFRHPDLAELRDPE
EEDPLEREARLAGISFVRLNGTVGCIVNGAGLSMATMDAIKLYGGEPANFLDIGGGASAQRVAAALRIVVADPNVRAILV
NIFGGITRGDVVAQGILEALRQVEVRVPMVIRLVGTRQEEGRRLLEEAGFTVVDTMEEAAQRAVALAQGQ

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=41.9847328244275, Blast_Score=319, Evalue=3e-87,
Organism=Homo sapiens, GI157779135, Length=380, Percent_Identity=40.7894736842105, Blast_Score=283, Evalue=3e-76,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=42.1487603305785, Blast_Score=274, Evalue=8e-74,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=47.9381443298969, Blast_Score=343, Evalue=9e-96,
Organism=Caenorhabditis elegans, GI17567829, Length=392, Percent_Identity=41.3265306122449, Blast_Score=296, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI17539378, Length=401, Percent_Identity=35.6608478802993, Blast_Score=254, Evalue=5e-68,
Organism=Saccharomyces cerevisiae, GI6321683, Length=397, Percent_Identity=41.0579345088161, Blast_Score=293, Evalue=3e-80,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=42.4936386768448, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=42.4936386768448, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=42.3857868020305, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=42.3857868020305, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI21356231, Length=391, Percent_Identity=37.5959079283887, Blast_Score=248, Evalue=7e-66,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42006; Mature: 42006

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGAVVESEGGAMDLHEYQAAELFARYGIPVNRGIVARTPEEASAAAEQLGGRVVVKAQV
CCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHCCCEEEEEEEE
HAGGRGKAGGIRLADDPVQAEAVARQILGMEIRGRIVRKVLVAPAVAFEREYYLGAVLDR
CCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEC
DSRRIVVMASSAGGVDIEEVARERPTAIVREQADPFLGFLDFQARRLAFRLGIEPDLVRG
CCCEEEEEECCCCCCCHHHHHHCCCHHHHHHCCCCCEEHHHHHHHHHHHCCCCCHHHHHH
FATIARQLYRAFVDNDASLAEINPLVLTQDRSWLALDTKVVLDDNGLFRHPDLAELRDPE
HHHHHHHHHHHHHCCCCCCEECCCEEEECCCCEEEEEEEEEECCCCCCCCCCHHHHCCCC
EEDPLEREARLAGISFVRLNGTVGCIVNGAGLSMATMDAIKLYGGEPANFLDIGGGASAQ
CCCCHHHHHHHHCEEEEEECCEEEEEEECCCCCHHHHHHHHHCCCCCCCEEECCCCCCHH
RVAAALRIVVADPNVRAILVNIFGGITRGDVVAQGILEALRQVEVRVPMVIRLVGTRQEE
HHHHEEEEEEECCCCEEEEEEHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
GRRLLEEAGFTVVDTMEEAAQRAVALAQGQ
HHHHHHHCCCEEEHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIGAVVESEGGAMDLHEYQAAELFARYGIPVNRGIVARTPEEASAAAEQLGGRVVVKAQV
CCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHCCCEEEEEEEE
HAGGRGKAGGIRLADDPVQAEAVARQILGMEIRGRIVRKVLVAPAVAFEREYYLGAVLDR
CCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEC
DSRRIVVMASSAGGVDIEEVARERPTAIVREQADPFLGFLDFQARRLAFRLGIEPDLVRG
CCCEEEEEECCCCCCCHHHHHHCCCHHHHHHCCCCCEEHHHHHHHHHHHCCCCCHHHHHH
FATIARQLYRAFVDNDASLAEINPLVLTQDRSWLALDTKVVLDDNGLFRHPDLAELRDPE
HHHHHHHHHHHHHCCCCCCEECCCEEEECCCCEEEEEEEEEECCCCCCCCCCHHHHCCCC
EEDPLEREARLAGISFVRLNGTVGCIVNGAGLSMATMDAIKLYGGEPANFLDIGGGASAQ
CCCCHHHHHHHHCEEEEEECCEEEEEEECCCCCHHHHHHHHHCCCCCCCEEECCCCCCHH
RVAAALRIVVADPNVRAILVNIFGGITRGDVVAQGILEALRQVEVRVPMVIRLVGTRQEE
HHHHEEEEEEECCCCEEEEEEHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
GRRLLEEAGFTVVDTMEEAAQRAVALAQGQ
HHHHHHHCCCEEEHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA