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The map label for this gene is fucA [H]

Identifier: 221633775

GI number: 221633775

Start: 1806792

End: 1807439

Strand: Reverse

Name: fucA [H]

Synonym: trd_1802

Alternate gene names: 221633775

Gene position: 1807439-1806792 (Counterclockwise)

Preceding gene: 221633776

Following gene: 221633774

Centisome position: 90.24

GC content: 63.58

Gene sequence:

>648_bases
ATGCCAGTCGAGCTCGTCCCACATCAGAGTCTCATCGCACTCGGTCGGCTGGCGGGGAGTCGCGGGTACCTGTGGGGGAC
TGGCGGTAACCTGAGCCTGCGGCGCAGCGAGTCGCACTTCCTCATCACCATGCGAGGAACCGCCCTCGACCAACTCGACT
CGCAAGATTTCGTTCTCGCCCCGCTCCAGGGCGAACGGGACGAGCCGCCGGAGGCCTCCACCGAGATTCAGCTGCACCGA
CGCATCTACCAGGCACGTCCCGATGTGCGCTGCGTGATCCATCTTTCTCCGTTCTACACGACGCTCGTCGCGTGCACCGA
CCTGGAACTCCCGACCGATATCGTTCCTGAAACAGCGTTGTACCTCGGTGAAATCGCTCGGGTACCCTACATTCAGCCTG
GCACTGACGAGTTGGCTCGGGCTGTCGCCGAGGCGCTCGGCAAAGAGCGCTCGGTCGTCATCATGGCGAATCACGGCGTG
GTCACCGTCGGCGAGTCTCCGCTCGATGCATTCCGGCGAGTCGAGGTGCTCGAGTTTCTCTGCCGCATGGTGGTGACAGC
CCGGAGCGCTGGACTGGAATTGCATCGGATCGGTCCCGACGCTGTCGCGAGCCTCCGCCGATCCTATGGCGTCAAGGCAC
GAGGGTAA

Upstream 100 bases:

>100_bases
GAGGCAGCTGGCGTGCACGTCGCGGAGCGACCGGCTGAGATAGCCGACTTGATGCGCGAGATCCTCGCGAACACGTGACG
ATGACAGACAGGAGAGGCGA

Downstream 100 bases:

>100_bases
GCCGTTCGCGTGTCAACTCGCCGGGCACGCTCCGGGCTGGTAGGCAGAAAGCTTGCCTGATCGCCTGGACAAAACAGCGA
TCGGTTGCGCTCTACCGCCA

Product: Class II Aldolase and Adducin N-terminal domain-containing protein

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MPVELVPHQSLIALGRLAGSRGYLWGTGGNLSLRRSESHFLITMRGTALDQLDSQDFVLAPLQGERDEPPEASTEIQLHR
RIYQARPDVRCVIHLSPFYTTLVACTDLELPTDIVPETALYLGEIARVPYIQPGTDELARAVAEALGKERSVVIMANHGV
VTVGESPLDAFRRVEVLEFLCRMVVTARSAGLELHRIGPDAVASLRRSYGVKARG

Sequences:

>Translated_215_residues
MPVELVPHQSLIALGRLAGSRGYLWGTGGNLSLRRSESHFLITMRGTALDQLDSQDFVLAPLQGERDEPPEASTEIQLHR
RIYQARPDVRCVIHLSPFYTTLVACTDLELPTDIVPETALYLGEIARVPYIQPGTDELARAVAEALGKERSVVIMANHGV
VTVGESPLDAFRRVEVLEFLCRMVVTARSAGLELHRIGPDAVASLRRSYGVKARG
>Mature_214_residues
PVELVPHQSLIALGRLAGSRGYLWGTGGNLSLRRSESHFLITMRGTALDQLDSQDFVLAPLQGERDEPPEASTEIQLHRR
IYQARPDVRCVIHLSPFYTTLVACTDLELPTDIVPETALYLGEIARVPYIQPGTDELARAVAEALGKERSVVIMANHGVV
TVGESPLDAFRRVEVLEFLCRMVVTARSAGLELHRIGPDAVASLRRSYGVKARG

Specific function: Catalyzes the reversible aldol cleavage of L-fuculose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde [H]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Homo sapiens, GI29826325, Length=217, Percent_Identity=34.5622119815668, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI29826323, Length=217, Percent_Identity=34.5622119815668, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI29826321, Length=217, Percent_Identity=34.1013824884793, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI89276787, Length=167, Percent_Identity=29.940119760479, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI297307160, Length=190, Percent_Identity=28.9473684210526, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI29826319, Length=217, Percent_Identity=34.1013824884793, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI9257190, Length=202, Percent_Identity=28.7128712871287, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI297307158, Length=167, Percent_Identity=29.940119760479, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI9257192, Length=167, Percent_Identity=29.940119760479, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI9943848, Length=189, Percent_Identity=27.5132275132275, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI9951927, Length=189, Percent_Identity=27.5132275132275, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI62912453, Length=189, Percent_Identity=27.5132275132275, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1789094, Length=178, Percent_Identity=30.3370786516854, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI1789164, Length=161, Percent_Identity=29.1925465838509, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 23623; Mature: 23492

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVELVPHQSLIALGRLAGSRGYLWGTGGNLSLRRSESHFLITMRGTALDQLDSQDFVLA
CCCCCCCCHHHHHHHHHCCCCCEEEECCCCEEEEECCCEEEEEECCCHHHHCCCCCEEEE
PLQGERDEPPEASTEIQLHRRIYQARPDVRCVIHLSPFYTTLVACTDLELPTDIVPETAL
CCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHCCCCCCCCCCCHHHH
YLGEIARVPYIQPGTDELARAVAEALGKERSVVIMANHGVVTVGESPLDAFRRVEVLEFL
HHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHH
CRMVVTARSAGLELHRIGPDAVASLRRSYGVKARG
HHHHHHHHHCCEEEEECCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PVELVPHQSLIALGRLAGSRGYLWGTGGNLSLRRSESHFLITMRGTALDQLDSQDFVLA
CCCCCCCHHHHHHHHHCCCCCEEEECCCCEEEEECCCEEEEEECCCHHHHCCCCCEEEE
PLQGERDEPPEASTEIQLHRRIYQARPDVRCVIHLSPFYTTLVACTDLELPTDIVPETAL
CCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHCCCCCCCCCCCHHHH
YLGEIARVPYIQPGTDELARAVAEALGKERSVVIMANHGVVTVGESPLDAFRRVEVLEFL
HHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHH
CRMVVTARSAGLELHRIGPDAVASLRRSYGVKARG
HHHHHHHHHCCEEEEECCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA