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The map label for this gene is soxA [H]

Identifier: 221633747

GI number: 221633747

Start: 1776387

End: 1777526

Strand: Reverse

Name: soxA [H]

Synonym: trd_1773

Alternate gene names: 221633747

Gene position: 1777526-1776387 (Counterclockwise)

Preceding gene: 221633748

Following gene: 221633744

Centisome position: 88.74

GC content: 64.47

Gene sequence:

>1140_bases
ATGCGGGAAGAGCGGGCGACAGTCATCGTGGTCGGTCTGGGCATCATGGGGTCGGCGACGGCCTGGGCGCTCGCGCGGCG
AGGCGTGCGCGTCGTGGGGCTGGAACAGTATGCGCCCTTTCACGCGCTGGGCTCGTCGCACGGGAAAACGCGGATCATCC
GCGAGGCCTACTTCGAGTCGCCGGAGTACGTGCCGCTGGTCCAGCGCGCTTATGAGCTGTGGGACGAGCTCGGCGAGCGA
ACTGGACGGAGGCTTTTGCGGGTGACCGGTGGTGTGAGTATCGGGCGGCTGGATAGCCCGTTCATCGTCGGGGCGCGCGA
GAGCGCGCAGCGGCACGGGCTGGCGCACGAACTGCTGGACGCGCAGGAAGCCCGAAAACGCTTTCCCGTGCTGGCGCTGC
CGGACGACTTCGTCGCGCTCGTCGAAGGGCGAGCGGGGATCCTCTTCGCGGAAGAGTGCTGGCGAGCCTTCTGTGAGGAT
GCGGTGCGGCATGGGGCGGAGCTGCGCTTCGGTGTGCGTGTGCACGGGTTTGCGCCGGACGGGGAAGGGATGACGGTGGA
GACCGAGAGCGGTCGACTGCGCGCGGATCGCGTGGTGGTGACTGCCGGACCGTGGTCAACGACATTGCTGGCTGATTTGG
GATTGCCGCTCGAGGTGCGGCGGGTGCTCGTCGTCCACGTCCAGCCTGACGATCCGACTCGGTTCCGACCAGAGGTGCTG
CCGATTTTCATCATGGACGTTCCAGAAGGTGAGTATTATGGTTTCCCCTTCTTGCCGGATCAGGGGGTGAAGTTCGGTCG
CCACGACGATGGCGAGGTGTGCACGCCGGAATCAGTGCGGAGGACGGTGACCGACGATGAGGTGCGCTGGATGACTGGAG
TCCTCCAACGGTATCTTCCCGGAGCCGCTCGCGAGGTCCTGATGACGGTGACCTGCCTGTATACGATGACCCCAGACAGT
CATTTCATGATCGACCGACATCCCGAGTGGCCACAGGTGGTCTTCGCTGCTGGTTTTTCCGGACACGGGTTCAAGTTCGC
GTCGGTGATGGGGGAGGCACTGGCTGATCTCGCACTGGAAGGCGCCAGTCGGTTACCGATCGGCTTTTTGAGCTTCCGCC
GATTGGCGAAGACTCAGTAA

Upstream 100 bases:

>100_bases
TTTCTCTCTTGGGCTGATATCCCGGGAGAGCGAGGAACACGGGAGACACACGTGCGACAATGGTGGAGATGAGCGATCGG
AGCGTGGAGGAAGAGAAGCG

Downstream 100 bases:

>100_bases
AAACGAGACCGTGTCCGGTGATAGGGAGGAGCGTCGGGCGGAAGGTTTTGGCCGAGTTGCCACAGTGCCCAGTCGACGCG
CCACGGAGCAGCGGGAAGGC

Product: sarcosine oxidase

Products: NA

Alternate protein names: MSOX [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MREERATVIVVGLGIMGSATAWALARRGVRVVGLEQYAPFHALGSSHGKTRIIREAYFESPEYVPLVQRAYELWDELGER
TGRRLLRVTGGVSIGRLDSPFIVGARESAQRHGLAHELLDAQEARKRFPVLALPDDFVALVEGRAGILFAEECWRAFCED
AVRHGAELRFGVRVHGFAPDGEGMTVETESGRLRADRVVVTAGPWSTTLLADLGLPLEVRRVLVVHVQPDDPTRFRPEVL
PIFIMDVPEGEYYGFPFLPDQGVKFGRHDDGEVCTPESVRRTVTDDEVRWMTGVLQRYLPGAAREVLMTVTCLYTMTPDS
HFMIDRHPEWPQVVFAAGFSGHGFKFASVMGEALADLALEGASRLPIGFLSFRRLAKTQ

Sequences:

>Translated_379_residues
MREERATVIVVGLGIMGSATAWALARRGVRVVGLEQYAPFHALGSSHGKTRIIREAYFESPEYVPLVQRAYELWDELGER
TGRRLLRVTGGVSIGRLDSPFIVGARESAQRHGLAHELLDAQEARKRFPVLALPDDFVALVEGRAGILFAEECWRAFCED
AVRHGAELRFGVRVHGFAPDGEGMTVETESGRLRADRVVVTAGPWSTTLLADLGLPLEVRRVLVVHVQPDDPTRFRPEVL
PIFIMDVPEGEYYGFPFLPDQGVKFGRHDDGEVCTPESVRRTVTDDEVRWMTGVLQRYLPGAAREVLMTVTCLYTMTPDS
HFMIDRHPEWPQVVFAAGFSGHGFKFASVMGEALADLALEGASRLPIGFLSFRRLAKTQ
>Mature_379_residues
MREERATVIVVGLGIMGSATAWALARRGVRVVGLEQYAPFHALGSSHGKTRIIREAYFESPEYVPLVQRAYELWDELGER
TGRRLLRVTGGVSIGRLDSPFIVGARESAQRHGLAHELLDAQEARKRFPVLALPDDFVALVEGRAGILFAEECWRAFCED
AVRHGAELRFGVRVHGFAPDGEGMTVETESGRLRADRVVVTAGPWSTTLLADLGLPLEVRRVLVVHVQPDDPTRFRPEVL
PIFIMDVPEGEYYGFPFLPDQGVKFGRHDDGEVCTPESVRRTVTDDEVRWMTGVLQRYLPGAAREVLMTVTCLYTMTPDS
HFMIDRHPEWPQVVFAAGFSGHGFKFASVMGEALADLALEGASRLPIGFLSFRRLAKTQ

Specific function: Catalyzes the oxidative demethylation of sarcosine [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MSOX/MTOX family. MSOX subfamily [H]

Homologues:

Organism=Homo sapiens, GI60499001, Length=365, Percent_Identity=34.5205479452055, Blast_Score=200, Evalue=2e-51,
Organism=Escherichia coli, GI1787298, Length=368, Percent_Identity=34.5108695652174, Blast_Score=194, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI115535191, Length=381, Percent_Identity=28.8713910761155, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI25147318, Length=390, Percent_Identity=27.9487179487179, Blast_Score=138, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002204
- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 42185; Mature: 42185

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREERATVIVVGLGIMGSATAWALARRGVRVVGLEQYAPFHALGSSHGKTRIIREAYFES
CCCCCEEEEEEECCCCCCHHHHHHHHCCEEEEEHHHCCCHHHHCCCCCCHHHHHHHHHCC
PEYVPLVQRAYELWDELGERTGRRLLRVTGGVSIGRLDSPFIVGARESAQRHGLAHELLD
CCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCEECCCCCCEEEECHHHHHHCCHHHHHHH
AQEARKRFPVLALPDDFVALVEGRAGILFAEECWRAFCEDAVRHGAELRFGVRVHGFAPD
HHHHHHHCCEEECCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEEEEECCC
GEGMTVETESGRLRADRVVVTAGPWSTTLLADLGLPLEVRRVLVVHVQPDDPTRFRPEVL
CCCEEEECCCCCEEECEEEEEECCCCHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCEE
PIFIMDVPEGEYYGFPFLPDQGVKFGRHDDGEVCTPESVRRTVTDDEVRWMTGVLQRYLP
EEEEEECCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCC
GAAREVLMTVTCLYTMTPDSHFMIDRHPEWPQVVFAAGFSGHGFKFASVMGEALADLALE
HHHHHHHHHHHHEEEECCCCCEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHC
GASRLPIGFLSFRRLAKTQ
CCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MREERATVIVVGLGIMGSATAWALARRGVRVVGLEQYAPFHALGSSHGKTRIIREAYFES
CCCCCEEEEEEECCCCCCHHHHHHHHCCEEEEEHHHCCCHHHHCCCCCCHHHHHHHHHCC
PEYVPLVQRAYELWDELGERTGRRLLRVTGGVSIGRLDSPFIVGARESAQRHGLAHELLD
CCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCEECCCCCCEEEECHHHHHHCCHHHHHHH
AQEARKRFPVLALPDDFVALVEGRAGILFAEECWRAFCEDAVRHGAELRFGVRVHGFAPD
HHHHHHHCCEEECCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEEEEECCC
GEGMTVETESGRLRADRVVVTAGPWSTTLLADLGLPLEVRRVLVVHVQPDDPTRFRPEVL
CCCEEEECCCCCEEECEEEEEECCCCHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCEE
PIFIMDVPEGEYYGFPFLPDQGVKFGRHDDGEVCTPESVRRTVTDDEVRWMTGVLQRYLP
EEEEEECCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCC
GAAREVLMTVTCLYTMTPDSHFMIDRHPEWPQVVFAAGFSGHGFKFASVMGEALADLALE
HHHHHHHHHHHHEEEECCCCCEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHC
GASRLPIGFLSFRRLAKTQ
CCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]