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The map label for this gene is obg

Identifier: 221633685

GI number: 221633685

Start: 1714851

End: 1716254

Strand: Reverse

Name: obg

Synonym: trd_1712

Alternate gene names: 221633685

Gene position: 1716254-1714851 (Counterclockwise)

Preceding gene: 221633686

Following gene: 221633683

Centisome position: 85.68

GC content: 65.03

Gene sequence:

>1404_bases
ATGTTCTACGACGAAGCCAAGATCTTCGTGAAGGCTGGAAACGGTGGGAACGGGGCGGTCAGTTTCCACCGGGAAAAGTA
CATACCGCGTGGTGGGCCCGATGGAGGCGATGGTGGGCGCGGGGGGAACGTGTATCTCCGCGTCGATCCCTCGCTCAACA
CGTTGCTCCCGTTCAGCTATCAGCGACAGTTCCGGGCCGAGGATGGACAGCCGGGTCAGGGAAACAACAAGAACGGTCGG
GACGGTGCGGATCTCTACATCGACGTTCCACCGGGAACCGTGGTGTACGACGAGGCCACTGGTGCGGTTCTCGGCGATCT
GCTCGAGCCGGGCGAGGTGTTGCTGGTCGCTCGTGGAGGGTTCGGTGGACGGGGCAATCAGCATTTCGCGACGCCGAGCC
GGCAGGCTCCGCGCTTCGCGGAAAAGGGAGAGCCCGGCGAGGAGCGCTGGCTGCGGCTGGAACTGAAGCTTTTGGCCGAT
GTCGGGCTGGTCGGTTTGCCCAACGCCGGCAAGTCAACGCTCTTGGCTGCAGTGAGCGCTGCTCGACCGAAGATCGCTGA
CTATCCCTTCACGACGCTGGAGCCAATGCTCGGCGTGGTGAGCGTGCCGGGTCGGGAGGGAGGAACGTTCGTCCTCGCCG
ATCTGCCAGGACTGATCGCTGGCGCCTCGCGTGGTGCTGGACTCGGCCATGAGTTCTTGCGCCATGTGGAGCGGACACGC
CTGCTCATCCATGTGCTGGACGGCTCCGGCGGACTCGAGGGGCGCGATCCACTGGAGGACTTTCACACGATCAATGCGGA
ACTCGCCGCCTATTCCGCATCGCTGGCTGGCAAGCCGCAGATCGTCGCGGTCAACAAGATGGATCTCCCCGAGGCACAGG
CCAACTGGCCGCGCATCGCGCGAGCACTGGACGAACTCGGTTACACGGCCTACCCGATCTCGGCGGCCACGGGACAAGGG
GTCGGCGAACTGATCCGCGCGACCTGGGAGCGCCTGCAGCAACTGCCTCGCCCCGAACGGGTCGCGCCGCCCCTGCGCAG
TCACCGGGTCTATACGCTCGATCGCTCGCAGGAGCGTTGGGAGGCGATCCGCTTGTCTCCTCACCACTTCGCGCTGCGAG
GTCCAAAGATCGAGCGACTCACGCTGATGACCGACTTTTCCAACCCGGAGGCAGCCGAACGGTACCAGCGGCTGCTGGCC
CGCTGGGGTATCTCCCGGCGGCTGCTCGCGCTCGGCATTCAGCCAGGCGATATCGTGCACGTGGCTGGACGCGAACTGGT
GTGGGAACCCGAGTTGGCGGAAGCTGAGCAGACTCGGCCGCGCCGGCGCTTGACCAAACGCGAGCGGCTCCTCAAGCGGG
CTGGCCTTTTGGAAGAACCGGAAGAAGAGATCGGCGAGCAGTGA

Upstream 100 bases:

>100_bases
CGCAGCGGGCGCGAGCACTCCGCGATTTCCTCGAGTAAGCTTGATCGTGTGTCAACGGAACGTTGCGAGCAGGTCTGCCG
AGCGGCAGGCCGGAGGGGTC

Downstream 100 bases:

>100_bases
CGTCCGCTCAACGGGAGACCGCGGTCGGTGTTTGGTCGCCCGTGATGCGTCGGACGTCGTAGACGTCCCTGACCGATTCC
AGCTTCTGGAGGATGCGGCT

Product: putative GTPase

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MFYDEAKIFVKAGNGGNGAVSFHREKYIPRGGPDGGDGGRGGNVYLRVDPSLNTLLPFSYQRQFRAEDGQPGQGNNKNGR
DGADLYIDVPPGTVVYDEATGAVLGDLLEPGEVLLVARGGFGGRGNQHFATPSRQAPRFAEKGEPGEERWLRLELKLLAD
VGLVGLPNAGKSTLLAAVSAARPKIADYPFTTLEPMLGVVSVPGREGGTFVLADLPGLIAGASRGAGLGHEFLRHVERTR
LLIHVLDGSGGLEGRDPLEDFHTINAELAAYSASLAGKPQIVAVNKMDLPEAQANWPRIARALDELGYTAYPISAATGQG
VGELIRATWERLQQLPRPERVAPPLRSHRVYTLDRSQERWEAIRLSPHHFALRGPKIERLTLMTDFSNPEAAERYQRLLA
RWGISRRLLALGIQPGDIVHVAGRELVWEPELAEAEQTRPRRRLTKRERLLKRAGLLEEPEEEIGEQ

Sequences:

>Translated_467_residues
MFYDEAKIFVKAGNGGNGAVSFHREKYIPRGGPDGGDGGRGGNVYLRVDPSLNTLLPFSYQRQFRAEDGQPGQGNNKNGR
DGADLYIDVPPGTVVYDEATGAVLGDLLEPGEVLLVARGGFGGRGNQHFATPSRQAPRFAEKGEPGEERWLRLELKLLAD
VGLVGLPNAGKSTLLAAVSAARPKIADYPFTTLEPMLGVVSVPGREGGTFVLADLPGLIAGASRGAGLGHEFLRHVERTR
LLIHVLDGSGGLEGRDPLEDFHTINAELAAYSASLAGKPQIVAVNKMDLPEAQANWPRIARALDELGYTAYPISAATGQG
VGELIRATWERLQQLPRPERVAPPLRSHRVYTLDRSQERWEAIRLSPHHFALRGPKIERLTLMTDFSNPEAAERYQRLLA
RWGISRRLLALGIQPGDIVHVAGRELVWEPELAEAEQTRPRRRLTKRERLLKRAGLLEEPEEEIGEQ
>Mature_467_residues
MFYDEAKIFVKAGNGGNGAVSFHREKYIPRGGPDGGDGGRGGNVYLRVDPSLNTLLPFSYQRQFRAEDGQPGQGNNKNGR
DGADLYIDVPPGTVVYDEATGAVLGDLLEPGEVLLVARGGFGGRGNQHFATPSRQAPRFAEKGEPGEERWLRLELKLLAD
VGLVGLPNAGKSTLLAAVSAARPKIADYPFTTLEPMLGVVSVPGREGGTFVLADLPGLIAGASRGAGLGHEFLRHVERTR
LLIHVLDGSGGLEGRDPLEDFHTINAELAAYSASLAGKPQIVAVNKMDLPEAQANWPRIARALDELGYTAYPISAATGQG
VGELIRATWERLQQLPRPERVAPPLRSHRVYTLDRSQERWEAIRLSPHHFALRGPKIERLTLMTDFSNPEAAERYQRLLA
RWGISRRLLALGIQPGDIVHVAGRELVWEPELAEAEQTRPRRRLTKRERLLKRAGLLEEPEEEIGEQ

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=324, Percent_Identity=43.8271604938272, Blast_Score=202, Evalue=5e-52,
Organism=Homo sapiens, GI111955139, Length=306, Percent_Identity=38.2352941176471, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI111955063, Length=267, Percent_Identity=37.0786516853933, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI4557537, Length=123, Percent_Identity=32.520325203252, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4758796, Length=130, Percent_Identity=34.6153846153846, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1789574, Length=328, Percent_Identity=52.4390243902439, Blast_Score=278, Evalue=4e-76,
Organism=Escherichia coli, GI1787454, Length=129, Percent_Identity=37.2093023255814, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790615, Length=208, Percent_Identity=33.6538461538462, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=298, Percent_Identity=40.6040268456376, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=387, Percent_Identity=29.9741602067183, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=32.3741007194245, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71981008, Length=121, Percent_Identity=36.3636363636364, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=194, Percent_Identity=39.6907216494845, Blast_Score=136, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6321612, Length=101, Percent_Identity=38.6138613861386, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319281, Length=132, Percent_Identity=34.0909090909091, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI20129375, Length=342, Percent_Identity=40.3508771929825, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24585318, Length=313, Percent_Identity=38.3386581469649, Blast_Score=168, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_THERP (B9L101)

Other databases:

- EMBL:   CP001275
- RefSeq:   YP_002522911.1
- GeneID:   7355443
- GenomeReviews:   CP001275_GR
- KEGG:   tro:trd_1712
- OMA:   IVHVLDC
- ProtClustDB:   CLSK2808140
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 51108; Mature: 51108

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYDEAKIFVKAGNGGNGAVSFHREKYIPRGGPDGGDGGRGGNVYLRVDPSLNTLLPFSY
CCCCCEEEEEEECCCCCCCEEEHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHH
QRQFRAEDGQPGQGNNKNGRDGADLYIDVPPGTVVYDEATGAVLGDLLEPGEVLLVARGG
HHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCHHHHHHHCCCCCEEEEEECC
FGGRGNQHFATPSRQAPRFAEKGEPGEERWLRLELKLLADVGLVGLPNAGKSTLLAAVSA
CCCCCCCCCCCCCCCCCCHHHCCCCCHHHEEEHEEHHHHCCCEEECCCCCHHHHHHHHHH
ARPKIADYPFTTLEPMLGVVSVPGREGGTFVLADLPGLIAGASRGAGLGHEFLRHVERTR
CCCCCCCCCCHHHHHHHHEEECCCCCCCEEEEECCCCHHHCCCCCCCCHHHHHHHHHHHE
LLIHVLDGSGGLEGRDPLEDFHTINAELAAYSASLAGKPQIVAVNKMDLPEAQANWPRIA
EEEEEECCCCCCCCCCCHHHHHHHCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHH
RALDELGYTAYPISAATGQGVGELIRATWERLQQLPRPERVAPPLRSHRVYTLDRSQERW
HHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHCCEEEEECCCHHHH
EAIRLSPHHFALRGPKIERLTLMTDFSNPEAAERYQRLLARWGISRRLLALGIQPGDIVH
HHHCCCCCEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEE
VAGRELVWEPELAEAEQTRPRRRLTKRERLLKRAGLLEEPEEEIGEQ
ECCCCEEECCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHCCC
>Mature Secondary Structure
MFYDEAKIFVKAGNGGNGAVSFHREKYIPRGGPDGGDGGRGGNVYLRVDPSLNTLLPFSY
CCCCCEEEEEEECCCCCCCEEEHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHH
QRQFRAEDGQPGQGNNKNGRDGADLYIDVPPGTVVYDEATGAVLGDLLEPGEVLLVARGG
HHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCHHHHHHHCCCCCEEEEEECC
FGGRGNQHFATPSRQAPRFAEKGEPGEERWLRLELKLLADVGLVGLPNAGKSTLLAAVSA
CCCCCCCCCCCCCCCCCCHHHCCCCCHHHEEEHEEHHHHCCCEEECCCCCHHHHHHHHHH
ARPKIADYPFTTLEPMLGVVSVPGREGGTFVLADLPGLIAGASRGAGLGHEFLRHVERTR
CCCCCCCCCCHHHHHHHHEEECCCCCCCEEEEECCCCHHHCCCCCCCCHHHHHHHHHHHE
LLIHVLDGSGGLEGRDPLEDFHTINAELAAYSASLAGKPQIVAVNKMDLPEAQANWPRIA
EEEEEECCCCCCCCCCCHHHHHHHCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHH
RALDELGYTAYPISAATGQGVGELIRATWERLQQLPRPERVAPPLRSHRVYTLDRSQERW
HHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHCCEEEEECCCHHHH
EAIRLSPHHFALRGPKIERLTLMTDFSNPEAAERYQRLLARWGISRRLLALGIQPGDIVH
HHHCCCCCEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEE
VAGRELVWEPELAEAEQTRPRRRLTKRERLLKRAGLLEEPEEEIGEQ
ECCCCEEECCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA