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The map label for this gene is yycG [H]

Identifier: 221633575

GI number: 221633575

Start: 1591041

End: 1592306

Strand: Reverse

Name: yycG [H]

Synonym: trd_1599

Alternate gene names: 221633575

Gene position: 1592306-1591041 (Counterclockwise)

Preceding gene: 221633576

Following gene: 221633574

Centisome position: 79.5

GC content: 70.77

Gene sequence:

>1266_bases
ATGCTCACGCTCTTCCTCGCCACCGCTCTCGCCTTCGTTGCCGGTGCGCTCGTCGCGCTGTTCTGGCAGCGTCACCGGTT
CGGCGCCGAGCTGCGCCGGATGCTCGCCCAGCTCCGCCGCGAGCATCCGACGATCGGCCCGCTCCAGCGACCGCTCCTCG
ACGCGCGGTCACTGGACGCGTTCCGGTTCCTGCTCGACGATGCGCTCCGCTTCCTGGAGCGCGAGCTGGAACAGGCCTCG
GCCCGGCAGAGCCAGCTGGCTGCCCTCTTCGATCACCTGAGCGATGGTGTCGTCCTCGTCGATCCGGATGGGCAGGTGGT
GAGCCTGAACCGTGCTGCTCGCGAACTCCTCCCCGGCGGCCGGAGCGAGGCGCTGGGTCGTCCGTACGCGGAAGTCCTGC
GCGACTACGAGCTCAACGAGCTGGTCGCCCGCGCGTTGGCTGGCGCGGCGCCGACGACCGGGCGCTTCGTCGAACTCGGT
CGACCGCGCCGGAGCATCCAGGCCCAGGTCTCTGTCCTCCAGGGTGCCGATCGCCCGCTGGTGACGCTCGTCCTGCGGGA
CATCACCGAGCTGCGCCGCACGGAAACGATCCGCCGCGACTTCGTCGCCAACGTCTCGCACGACCTGCGGACGCCACTGG
CGGCCCTGCAAGCCCTGGTGGAAACGCTCCTGGACGGCGCGCTGGCTGATCCGGCGGTCGCCGAGGACTTCTTGCGGCGC
ATCGCCGTCGAGGTGGAGCACATGACTCGCCTGGTGAACCAGCTCCTGGAACTGACCAAGGCCGAGAGCGGCCAGTTACA
GCTCGCTCGTGTCCCGACTGACCTTGCCGAGCTGGCCCGCGCGACGCTGCGCCGCTTCGAGCCGCGGGCCGCCAGCAAAG
GCATCGCGCTCACCGTGCAGGTCGCCCCGGAACTGCCCCCGGTCGCCTGCGATCCGGAGCGGATCGGCCAGGTGCTGGCC
AACCTCTTGGACAACGCGCTCAAGTTCACCCCGGCAGGAGGCCAGATCACGGTCGAGATCGCTGCCGCTTCCGGGGAGGC
CATCGTTCGCGTCCGCGACACCGGGCCAGGGATCCCCGCCGACGAGCTCGATCGCGTCTTCGAGCGCTTTTTCAAAGGTG
ACCGGGCGCGGAGCGGGGGCGGCAGCGGGCTCGGGCTGGCGATCGTCAAGCACCTCGTCCAGCTGCACGGCGGGCGAGTG
TGGGCGGAGAGCCCGCCGGGAGGCGGCGCGATCGTCGGCTTCGCGCTCCCGCTGGAACGGCGCTGA

Upstream 100 bases:

>100_bases
TGACCGCGCGCTCACCACAAGCGACACGCCGCTGATGGTCATCGCTCCGTCACGATTTCCGCTCGTGCGATCGGTACGCT
CCCATCGAGGGTAGCCAGCG

Downstream 100 bases:

>100_bases
TCGTAACACGATCGCCACACACGCCGGCTGCTGAGCGCGTATCGTTCCCGACGGAAACGAACGACGCACACCTCGCGCAG
CCCCGTACTCCTCCTCACGC

Product: histidine kinase PhoR1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MLTLFLATALAFVAGALVALFWQRHRFGAELRRMLAQLRREHPTIGPLQRPLLDARSLDAFRFLLDDALRFLERELEQAS
ARQSQLAALFDHLSDGVVLVDPDGQVVSLNRAARELLPGGRSEALGRPYAEVLRDYELNELVARALAGAAPTTGRFVELG
RPRRSIQAQVSVLQGADRPLVTLVLRDITELRRTETIRRDFVANVSHDLRTPLAALQALVETLLDGALADPAVAEDFLRR
IAVEVEHMTRLVNQLLELTKAESGQLQLARVPTDLAELARATLRRFEPRAASKGIALTVQVAPELPPVACDPERIGQVLA
NLLDNALKFTPAGGQITVEIAAASGEAIVRVRDTGPGIPADELDRVFERFFKGDRARSGGGSGLGLAIVKHLVQLHGGRV
WAESPPGGGAIVGFALPLERR

Sequences:

>Translated_421_residues
MLTLFLATALAFVAGALVALFWQRHRFGAELRRMLAQLRREHPTIGPLQRPLLDARSLDAFRFLLDDALRFLERELEQAS
ARQSQLAALFDHLSDGVVLVDPDGQVVSLNRAARELLPGGRSEALGRPYAEVLRDYELNELVARALAGAAPTTGRFVELG
RPRRSIQAQVSVLQGADRPLVTLVLRDITELRRTETIRRDFVANVSHDLRTPLAALQALVETLLDGALADPAVAEDFLRR
IAVEVEHMTRLVNQLLELTKAESGQLQLARVPTDLAELARATLRRFEPRAASKGIALTVQVAPELPPVACDPERIGQVLA
NLLDNALKFTPAGGQITVEIAAASGEAIVRVRDTGPGIPADELDRVFERFFKGDRARSGGGSGLGLAIVKHLVQLHGGRV
WAESPPGGGAIVGFALPLERR
>Mature_421_residues
MLTLFLATALAFVAGALVALFWQRHRFGAELRRMLAQLRREHPTIGPLQRPLLDARSLDAFRFLLDDALRFLERELEQAS
ARQSQLAALFDHLSDGVVLVDPDGQVVSLNRAARELLPGGRSEALGRPYAEVLRDYELNELVARALAGAAPTTGRFVELG
RPRRSIQAQVSVLQGADRPLVTLVLRDITELRRTETIRRDFVANVSHDLRTPLAALQALVETLLDGALADPAVAEDFLRR
IAVEVEHMTRLVNQLLELTKAESGQLQLARVPTDLAELARATLRRFEPRAASKGIALTVQVAPELPPVACDPERIGQVLA
NLLDNALKFTPAGGQITVEIAAASGEAIVRVRDTGPGIPADELDRVFERFFKGDRARSGGGSGLGLAIVKHLVQLHGGRV
WAESPPGGGAIVGFALPLERR

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=236, Percent_Identity=37.2881355932203, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786600, Length=333, Percent_Identity=33.3333333333333, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1788713, Length=364, Percent_Identity=28.8461538461538, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=33.4782608695652, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI48994928, Length=246, Percent_Identity=33.3333333333333, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788549, Length=352, Percent_Identity=26.1363636363636, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI145693157, Length=221, Percent_Identity=32.579185520362, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786912, Length=226, Percent_Identity=34.5132743362832, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=31.8965517241379, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1790861, Length=216, Percent_Identity=35.1851851851852, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790300, Length=352, Percent_Identity=28.9772727272727, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786783, Length=219, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1790346, Length=237, Percent_Identity=31.2236286919831, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081816, Length=280, Percent_Identity=30.7142857142857, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789808, Length=225, Percent_Identity=31.1111111111111, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789403, Length=215, Percent_Identity=31.6279069767442, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788279, Length=201, Percent_Identity=26.865671641791, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=27.3913043478261, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=29.1479820627803, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790551, Length=232, Percent_Identity=29.7413793103448, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787374, Length=268, Percent_Identity=25.3731343283582, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45816; Mature: 45816

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLFLATALAFVAGALVALFWQRHRFGAELRRMLAQLRREHPTIGPLQRPLLDARSLDA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
FRFLLDDALRFLERELEQASARQSQLAALFDHLSDGVVLVDPDGQVVSLNRAARELLPGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEHHHHHHHHCCCC
RSEALGRPYAEVLRDYELNELVARALAGAAPTTGRFVELGRPRRSIQAQVSVLQGADRPL
CCHHCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCHHCCCCCHHHHHHHHHHHHCCCCHH
VTLVLRDITELRRTETIRRDFVANVSHDLRTPLAALQALVETLLDGALADPAVAEDFLRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IAVEVEHMTRLVNQLLELTKAESGQLQLARVPTDLAELARATLRRFEPRAASKGIALTVQ
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEE
VAPELPPVACDPERIGQVLANLLDNALKFTPAGGQITVEIAAASGEAIVRVRDTGPGIPA
ECCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEECCCCEEEEEECCCCCCCH
DELDRVFERFFKGDRARSGGGSGLGLAIVKHLVQLHGGRVWAESPPGGGAIVGFALPLER
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCEEEEEECCCCC
R
C
>Mature Secondary Structure
MLTLFLATALAFVAGALVALFWQRHRFGAELRRMLAQLRREHPTIGPLQRPLLDARSLDA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
FRFLLDDALRFLERELEQASARQSQLAALFDHLSDGVVLVDPDGQVVSLNRAARELLPGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEHHHHHHHHCCCC
RSEALGRPYAEVLRDYELNELVARALAGAAPTTGRFVELGRPRRSIQAQVSVLQGADRPL
CCHHCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCHHCCCCCHHHHHHHHHHHHCCCCHH
VTLVLRDITELRRTETIRRDFVANVSHDLRTPLAALQALVETLLDGALADPAVAEDFLRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IAVEVEHMTRLVNQLLELTKAESGQLQLARVPTDLAELARATLRRFEPRAASKGIALTVQ
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEE
VAPELPPVACDPERIGQVLANLLDNALKFTPAGGQITVEIAAASGEAIVRVRDTGPGIPA
ECCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEECCCCEEEEEECCCCCCCH
DELDRVFERFFKGDRARSGGGSGLGLAIVKHLVQLHGGRVWAESPPGGGAIVGFALPLER
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCEEEEEECCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]