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The map label for this gene is cmtR [H]

Identifier: 221633507

GI number: 221633507

Start: 1509550

End: 1509921

Strand: Reverse

Name: cmtR [H]

Synonym: trd_1529

Alternate gene names: 221633507

Gene position: 1509921-1509550 (Counterclockwise)

Preceding gene: 221633509

Following gene: 221633506

Centisome position: 75.38

GC content: 65.59

Gene sequence:

>372_bases
ATGGTCGACCGGCGACAGTTGGAAATCAAGGCCAAACTCTTTCGCGGATTCGCTGATCCGAGCCGTCTGGCCATCCTCGA
AGTCCTCCGGTCGGCACCGGCGACGGTGGGAGAAATCGCTGCCTCGACGGGTCAGGGACTCTCCAACGTCTCCAATCATC
TTCGCTGCTTGCGTGACTGCGGACTGGTCGTGCGCCAGCGAGACGGGCAGCGGGTCCGCTACAGCTTGAGCGACCAGCGC
GTGGCGGCGCTCCTGGAACTGGCGGAACGGGTGCTCGCGGAGAGCGCCACCGGAGTCGCTTCCTGCCCGCGTTACGATCG
GGTCGAAGAGCATCCGGAGGTTGGCGATGGCCGAGTCGGTGCGCTCCGCTGA

Upstream 100 bases:

>100_bases
CAGCGTGACACACGTGGTGACTCGTCGCGTCGCTGGTTGCCTCGCGCTGGGGCGGTCGGGTATGCTGAGGTTCAGTAATT
GCTGAAATGCTGGAGAGCAT

Downstream 100 bases:

>100_bases
CGAACAGCAGCGCTGGACGACCCTCATTCTCCCGGTGGCGGAGCTGGATTGCGCGGAGTGCGCGCAGCACGTCGAGCAGG
CGCTCCGGACGGTGCCGGGC

Product: putative ArsR-family regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MVDRRQLEIKAKLFRGFADPSRLAILEVLRSAPATVGEIAASTGQGLSNVSNHLRCLRDCGLVVRQRDGQRVRYSLSDQR
VAALLELAERVLAESATGVASCPRYDRVEEHPEVGDGRVGALR

Sequences:

>Translated_123_residues
MVDRRQLEIKAKLFRGFADPSRLAILEVLRSAPATVGEIAASTGQGLSNVSNHLRCLRDCGLVVRQRDGQRVRYSLSDQR
VAALLELAERVLAESATGVASCPRYDRVEEHPEVGDGRVGALR
>Mature_123_residues
MVDRRQLEIKAKLFRGFADPSRLAILEVLRSAPATVGEIAASTGQGLSNVSNHLRCLRDCGLVVRQRDGQRVRYSLSDQR
VAALLELAERVLAESATGVASCPRYDRVEEHPEVGDGRVGALR

Specific function: Metal-responsive transcriptional repressor for the cmt operon. Binding of cadmium or lead causes the repressor to dissociate from the DNA [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 13469; Mature: 13469

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDRRQLEIKAKLFRGFADPSRLAILEVLRSAPATVGEIAASTGQGLSNVSNHLRCLRDC
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
GLVVRQRDGQRVRYSLSDQRVAALLELAERVLAESATGVASCPRYDRVEEHPEVGDGRVG
HHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCC
ALR
CCC
>Mature Secondary Structure
MVDRRQLEIKAKLFRGFADPSRLAILEVLRSAPATVGEIAASTGQGLSNVSNHLRCLRDC
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
GLVVRQRDGQRVRYSLSDQRVAALLELAERVLAESATGVASCPRYDRVEEHPEVGDGRVG
HHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCC
ALR
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]