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The map label for this gene is lysK [H]

Identifier: 221633498

GI number: 221633498

Start: 1500324

End: 1501418

Strand: Reverse

Name: lysK [H]

Synonym: trd_1520

Alternate gene names: 221633498

Gene position: 1501418-1500324 (Counterclockwise)

Preceding gene: 221633499

Following gene: 221633497

Centisome position: 74.96

GC content: 66.76

Gene sequence:

>1095_bases
ATGACCACCGAACTCGCTGTCGAGGCGGCTGCATTTCTCGAAGCGTTCCTCCGGATCCCGAGTTTGTCGGGGCAGGAAGC
TGCTGCCGTCGAGTGGCTCTGCTCGCGCATGAGCCAGTTCGGCTATGCAGCAGGACCCGATGAGGCTGGGAACGCGGTCG
GTACCCGCGGAAGCGGGCCGCGCGAGTTGATGCTCCTGGGACATATCGATACCGTGCCCGGTCGCATACCGGTGCGCCAG
GTCGATGGCTTGCTCTACGGCCGCGGAGCAGTCGATGCCAAGGGACCGCTGGCCGCCTTCGTGCTGGCGGGGGCACGAGC
GCAGCTGCCGCCCGGCATCCGCTTGACGGTCGTCGGCGCGGTCGAGGAAGAGGTGATGAGTTCGCGGGGCGCCAACTGGC
TGGTCGAGCACCATTCCCGTCCCGATGCCGTCATCATCGGCGAGCCGAGTGGATGGGACGGTGTCGTCCTTGGTTACAAG
GGCTCGGTCGCGATCGAGTACCGCATCGTGCGACCGTCAGCGCATGCTGCTGGACCGAGCACGACCGCCGCGGAGGATGC
GGTGGCGTTCTGGAATGCACTGGTCGCCTGGTGCGAGGAGCAGAATACCGGGCGCACACGCGAGTTCGACCGGGTGACGC
CGACCCTCTTGAGCATCGTGACCAACGGGGATGGCCTGACCGAGCAGGCCTGGCTGCGTGCGAATCTCCGCTTGCCACCC
GGCTTTCCGCCCGAGAAGGCGGTCGCCGCGGCCCAGCGACTAGCTGGTGCCGGTGACGTCGTCACGACGGTCAATGCAGC
GGGATTTCGCGTCGAAAAGCGTTCGCCGCTCGTCTCCGCCTTTCTCTCGGCGATCCGCGAGGTCGGCGGCGAGCCGAAGC
TCAAGGTGAAGACGGGAACGTCGGACATGAACATCGTCGGGCCGGCGTGGGGGTGCCCGATCGTCGCCTATGGTCCTGGC
GACTCGCGGCTGGACCACACGCCGAACGAGCATATCGCGATCGAGGAGTTCCTGCGCGGGATCATGGTCCTAGAGCGGGT
GATCGAACGCGTGGCAGCCCAGATCGTGGGTGGGCGATGGGGGGACGAGTCGTGA

Upstream 100 bases:

>100_bases
TCCGCGATCTCGCCGAGCTGGGTGTGCCGGTCGCAGAGCGGATCGCCGCGTTTGTCCTGGAGCAAGTACGCGTGGGGCGC
TCGGAAGACGAGGGGCAGCG

Downstream 100 bases:

>100_bases
GTGCACCGCGGATCGGTGTCTTGCTCTCGCATGTCCGGGAAGAGGAGAAGCTGCTCCTGCGTGCGCTCAGCGAGCGGGGA
GCCGAGGTCGTGCGCCTCTA

Product: acetyl-lysine deacetylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MTTELAVEAAAFLEAFLRIPSLSGQEAAAVEWLCSRMSQFGYAAGPDEAGNAVGTRGSGPRELMLLGHIDTVPGRIPVRQ
VDGLLYGRGAVDAKGPLAAFVLAGARAQLPPGIRLTVVGAVEEEVMSSRGANWLVEHHSRPDAVIIGEPSGWDGVVLGYK
GSVAIEYRIVRPSAHAAGPSTTAAEDAVAFWNALVAWCEEQNTGRTREFDRVTPTLLSIVTNGDGLTEQAWLRANLRLPP
GFPPEKAVAAAQRLAGAGDVVTTVNAAGFRVEKRSPLVSAFLSAIREVGGEPKLKVKTGTSDMNIVGPAWGCPIVAYGPG
DSRLDHTPNEHIAIEEFLRGIMVLERVIERVAAQIVGGRWGDES

Sequences:

>Translated_364_residues
MTTELAVEAAAFLEAFLRIPSLSGQEAAAVEWLCSRMSQFGYAAGPDEAGNAVGTRGSGPRELMLLGHIDTVPGRIPVRQ
VDGLLYGRGAVDAKGPLAAFVLAGARAQLPPGIRLTVVGAVEEEVMSSRGANWLVEHHSRPDAVIIGEPSGWDGVVLGYK
GSVAIEYRIVRPSAHAAGPSTTAAEDAVAFWNALVAWCEEQNTGRTREFDRVTPTLLSIVTNGDGLTEQAWLRANLRLPP
GFPPEKAVAAAQRLAGAGDVVTTVNAAGFRVEKRSPLVSAFLSAIREVGGEPKLKVKTGTSDMNIVGPAWGCPIVAYGPG
DSRLDHTPNEHIAIEEFLRGIMVLERVIERVAAQIVGGRWGDES
>Mature_363_residues
TTELAVEAAAFLEAFLRIPSLSGQEAAAVEWLCSRMSQFGYAAGPDEAGNAVGTRGSGPRELMLLGHIDTVPGRIPVRQV
DGLLYGRGAVDAKGPLAAFVLAGARAQLPPGIRLTVVGAVEEEVMSSRGANWLVEHHSRPDAVIIGEPSGWDGVVLGYKG
SVAIEYRIVRPSAHAAGPSTTAAEDAVAFWNALVAWCEEQNTGRTREFDRVTPTLLSIVTNGDGLTEQAWLRANLRLPPG
FPPEKAVAAAQRLAGAGDVVTTVNAAGFRVEKRSPLVSAFLSAIREVGGEPKLKVKTGTSDMNIVGPAWGCPIVAYGPGD
SRLDHTPNEHIAIEEFLRGIMVLERVIERVAAQIVGGRWGDES

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fifth step. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. LysK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788816, Length=376, Percent_Identity=27.3936170212766, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789236, Length=367, Percent_Identity=25.0681198910082, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010175
- InterPro:   IPR002933 [H]

Pfam domain/function: PF01546 Peptidase_M20 [H]

EC number: 3.5.1.-

Molecular weight: Translated: 38525; Mature: 38394

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTELAVEAAAFLEAFLRIPSLSGQEAAAVEWLCSRMSQFGYAAGPDEAGNAVGTRGSGP
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
RELMLLGHIDTVPGRIPVRQVDGLLYGRGAVDAKGPLAAFVLAGARAQLPPGIRLTVVGA
CEEEEEECCCCCCCCCCHHHHCCEEECCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEEEH
VEEEVMSSRGANWLVEHHSRPDAVIIGEPSGWDGVVLGYKGSVAIEYRIVRPSAHAAGPS
HHHHHHHCCCCCEEEEECCCCCEEEEECCCCCCCEEEEECCCEEEEEEEECCCCCCCCCC
TTAAEDAVAFWNALVAWCEEQNTGRTREFDRVTPTLLSIVTNGDGLTEQAWLRANLRLPP
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEECCCCCCCCHHHEECCCCCC
GFPPEKAVAAAQRLAGAGDVVTTVNAAGFRVEKRSPLVSAFLSAIREVGGEPKLKVKTGT
CCCHHHHHHHHHHHCCCCCCEEEECCCCEEECCCCHHHHHHHHHHHHCCCCCEEEEEECC
SDMNIVGPAWGCPIVAYGPGDSRLDHTPNEHIAIEEFLRGIMVLERVIERVAAQIVGGRW
CCCEEECCCCCCCEEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
GDES
CCCC
>Mature Secondary Structure 
TTELAVEAAAFLEAFLRIPSLSGQEAAAVEWLCSRMSQFGYAAGPDEAGNAVGTRGSGP
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
RELMLLGHIDTVPGRIPVRQVDGLLYGRGAVDAKGPLAAFVLAGARAQLPPGIRLTVVGA
CEEEEEECCCCCCCCCCHHHHCCEEECCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEEEH
VEEEVMSSRGANWLVEHHSRPDAVIIGEPSGWDGVVLGYKGSVAIEYRIVRPSAHAAGPS
HHHHHHHCCCCCEEEEECCCCCEEEEECCCCCCCEEEEECCCEEEEEEEECCCCCCCCCC
TTAAEDAVAFWNALVAWCEEQNTGRTREFDRVTPTLLSIVTNGDGLTEQAWLRANLRLPP
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEECCCCCCCCHHHEECCCCCC
GFPPEKAVAAAQRLAGAGDVVTTVNAAGFRVEKRSPLVSAFLSAIREVGGEPKLKVKTGT
CCCHHHHHHHHHHHCCCCCCEEEECCCCEEECCCCHHHHHHHHHHHHCCCCCEEEEEECC
SDMNIVGPAWGCPIVAYGPGDSRLDHTPNEHIAIEEFLRGIMVLERVIERVAAQIVGGRW
CCCEEECCCCCCCEEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
GDES
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA