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The map label for this gene is mhpF [C]

Identifier: 221633373

GI number: 221633373

Start: 1382460

End: 1383554

Strand: Reverse

Name: mhpF [C]

Synonym: trd_1393

Alternate gene names: 221633373

Gene position: 1383554-1382460 (Counterclockwise)

Preceding gene: 221633374

Following gene: 221633372

Centisome position: 69.07

GC content: 63.56

Gene sequence:

>1095_bases
TTGTGCGGCCGCGCCGATCCGCGACGAGAGCGGTCACGTCATCGCGGCGATGAGTCTCTCGGTGCCGGCCTACCGCTTCT
ATCCGAACCGACAGCGGCTCACCACCGCGATCGTCGATGCTGCGCGACGGGTTTCGGAAGAACTCGGGTACTATCAGGAG
GATTGGGCATGGGAGAACGGCAAGCGGTCAAGGTCGCGATCCTCGGTACCGGGAATATCGGTACCGACCTGATGTACAAG
CTCTTGCGGAATCCGGGCCACATGGAATTGGCCATGTTCGCCGGGATCGATCCGCAGTCGGAGGGGATCGCCCGCGCCAA
GAAACTAGGTATCCCGACGAGCTACGAGGGGATCAAGGCGGTCCTGGATGACCCCGAGATCCGGATCGTGTTCGATGCCA
CCAGCGCCAAAGCGCACGTTCGTCACGCCAAGATGCTGCGCGAGGCTGGCAAGATCGCGATCGATCTGACGCCAGCTGCC
CGCGGTCCGTACGTCGTGCCGCCGGTCAACCTCGGCGCACACCTGGACAAGGACAACGTCAACCTGATCACTTGCGGCGG
GCAGGCGACCATCCCGCTCGTCTTTGCTGTCAGTCGCGTCGTACCGGTGCGCTACGCCGAGATCGTCTCGACCGTCGCCA
GCAAGTCGGCGGGACCAGGAACGCGGCAGAACATCGACGAGTTCACGTTCACGACCGCCCATGGGCTCGAGGCGATCGGG
GGAGCTGAGCAGGGGAAGGCGATCATCATTCTCAACCCGGCTGAGCCGCCGATCATCATGCGCAATACCGTGTACGTCAT
TCCCGCGAACGAGGAGTTCGACCAGGCGGCGATCGTGGCGTCGGTCGACCAGATGGTCGCCGAAGTGCAGCAATACGTCC
CCGGGTATCGCCTCAAGGACGCGCCGGTCTTCGACCGGCGGCGCACACCGTGGGGCGAACGAACAATTATCGCCATGTTG
CTCGAGGTCGAGGGGGCCGGTGATTTCTTGCCGCCCTATTCCGGCAATCTCGACATCATGACGGCAGCGGCCTGGCGGGT
GGGTGAGTTGTTCGCCCAGCATTTGCTGGGTATCCGGCAGGAGGTGGCGGCATGA

Upstream 100 bases:

>100_bases
CGAACACGATCAAGTCGGTCGAGCAGCTGCGCGAAGAACTGGAACGGGTCCGCCAGCAGGGGTTCGCCTATGACCAGGAA
GAGGTGATGGTTGGGCTCTG

Downstream 100 bases:

>100_bases
AGACGCTCACGCCACCGCGCGTGACCGACACGACGCTGCGGGACGGTTCCCATGCCATGCGGCACCAGTTCACGCGGGAG
CAAGTGCGGGCCATCGTGGC

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating] [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MCGRADPRRERSRHRGDESLGAGLPLLSEPTAAHHRDRRCCATGFGRTRVLSGGLGMGERQAVKVAILGTGNIGTDLMYK
LLRNPGHMELAMFAGIDPQSEGIARAKKLGIPTSYEGIKAVLDDPEIRIVFDATSAKAHVRHAKMLREAGKIAIDLTPAA
RGPYVVPPVNLGAHLDKDNVNLITCGGQATIPLVFAVSRVVPVRYAEIVSTVASKSAGPGTRQNIDEFTFTTAHGLEAIG
GAEQGKAIIILNPAEPPIIMRNTVYVIPANEEFDQAAIVASVDQMVAEVQQYVPGYRLKDAPVFDRRRTPWGERTIIAML
LEVEGAGDFLPPYSGNLDIMTAAAWRVGELFAQHLLGIRQEVAA

Sequences:

>Translated_364_residues
MCGRADPRRERSRHRGDESLGAGLPLLSEPTAAHHRDRRCCATGFGRTRVLSGGLGMGERQAVKVAILGTGNIGTDLMYK
LLRNPGHMELAMFAGIDPQSEGIARAKKLGIPTSYEGIKAVLDDPEIRIVFDATSAKAHVRHAKMLREAGKIAIDLTPAA
RGPYVVPPVNLGAHLDKDNVNLITCGGQATIPLVFAVSRVVPVRYAEIVSTVASKSAGPGTRQNIDEFTFTTAHGLEAIG
GAEQGKAIIILNPAEPPIIMRNTVYVIPANEEFDQAAIVASVDQMVAEVQQYVPGYRLKDAPVFDRRRTPWGERTIIAML
LEVEGAGDFLPPYSGNLDIMTAAAWRVGELFAQHLLGIRQEVAA
>Mature_364_residues
MCGRADPRRERSRHRGDESLGAGLPLLSEPTAAHHRDRRCCATGFGRTRVLSGGLGMGERQAVKVAILGTGNIGTDLMYK
LLRNPGHMELAMFAGIDPQSEGIARAKKLGIPTSYEGIKAVLDDPEIRIVFDATSAKAHVRHAKMLREAGKIAIDLTPAA
RGPYVVPPVNLGAHLDKDNVNLITCGGQATIPLVFAVSRVVPVRYAEIVSTVASKSAGPGTRQNIDEFTFTTAHGLEAIG
GAEQGKAIIILNPAEPPIIMRNTVYVIPANEEFDQAAIVASVDQMVAEVQQYVPGYRLKDAPVFDRRRTPWGERTIIAML
LEVEGAGDFLPPYSGNLDIMTAAAWRVGELFAQHLLGIRQEVAA

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds [H]

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786547, Length=314, Percent_Identity=55.4140127388535, Blast_Score=322, Evalue=2e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534 [H]

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh [H]

EC number: =1.2.1.10 [H]

Molecular weight: Translated: 39196; Mature: 39196

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGRADPRRERSRHRGDESLGAGLPLLSEPTAAHHRDRRCCATGFGRTRVLSGGLGMGER
CCCCCCCHHHHHHHCCCHHHCCCCCCCCCCCHHHHCCCHHHHCCCCCCEEEECCCCCCCC
QAVKVAILGTGNIGTDLMYKLLRNPGHMELAMFAGIDPQSEGIARAKKLGIPTSYEGIKA
CEEEEEEEECCCCCHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHH
VLDDPEIRIVFDATSAKAHVRHAKMLREAGKIAIDLTPAARGPYVVPPVNLGAHLDKDNV
HCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCCCCEECCCCE
NLITCGGQATIPLVFAVSRVVPVRYAEIVSTVASKSAGPGTRQNIDEFTFTTAHGLEAIG
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEEEHHHCHHHHC
GAEQGKAIIILNPAEPPIIMRNTVYVIPANEEFDQAAIVASVDQMVAEVQQYVPGYRLKD
CCCCCCEEEEECCCCCCEEEECEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEECC
APVFDRRRTPWGERTIIAMLLEVEGAGDFLPPYSGNLDIMTAAAWRVGELFAQHLLGIRQ
CCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
EVAA
HHCC
>Mature Secondary Structure
MCGRADPRRERSRHRGDESLGAGLPLLSEPTAAHHRDRRCCATGFGRTRVLSGGLGMGER
CCCCCCCHHHHHHHCCCHHHCCCCCCCCCCCHHHHCCCHHHHCCCCCCEEEECCCCCCCC
QAVKVAILGTGNIGTDLMYKLLRNPGHMELAMFAGIDPQSEGIARAKKLGIPTSYEGIKA
CEEEEEEEECCCCCHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHH
VLDDPEIRIVFDATSAKAHVRHAKMLREAGKIAIDLTPAARGPYVVPPVNLGAHLDKDNV
HCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCCCCEECCCCE
NLITCGGQATIPLVFAVSRVVPVRYAEIVSTVASKSAGPGTRQNIDEFTFTTAHGLEAIG
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEEEHHHCHHHHC
GAEQGKAIIILNPAEPPIIMRNTVYVIPANEEFDQAAIVASVDQMVAEVQQYVPGYRLKD
CCCCCCEEEEECCCCCCEEEECEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEECC
APVFDRRRTPWGERTIIAMLLEVEGAGDFLPPYSGNLDIMTAAAWRVGELFAQHLLGIRQ
CCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
EVAA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA