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The map label for this gene is msrR [H]

Identifier: 221633317

GI number: 221633317

Start: 1327230

End: 1328843

Strand: Reverse

Name: msrR [H]

Synonym: trd_1336

Alternate gene names: 221633317

Gene position: 1328843-1327230 (Counterclockwise)

Preceding gene: 221633319

Following gene: 221633310

Centisome position: 66.34

GC content: 68.09

Gene sequence:

>1614_bases
ATGCCGCTCAGTGATGCTGACCTGGAGCGTCGACCACCGCGAACGAGCGCTATCCGGGCATTGGCTGGCTGGCGCGCCGC
GATCGCGTTCATCACCTCGGTTCTCTGGCCGGGAGCAGGTCATTGGATCGCCGGGCGCCCGTGGCGCGGGCTCGCCCTCG
GCGTCCCGCCCGCGCTCGCGCTCGGTTTTCTGCTCTGGCAGGCGAGCCAGCTTCCCGGTTGGGGAGTCACCTGGTTGCTG
CGCCCGAGCGTTCTGCGCGGCTTGATGATCGGGAACATCGTTCTGGGCAGCTACCGGGCTGTCGCACTGCTCGACCTCGT
GCGCATCGCCCTCGCTGGGCGGAGTCGAAGCTGTGCGGGGAAACGCGGACCGTACTTGGTCCTCGCAGCGCTGCTCGTGG
GGTCGGTGGTCACGCCGCACGCTGCGGTCGGCTTGGTGCTCACCCGCTGGTCACGCTTCCTCGATACGACGTTCCCCGCT
GCAGCCGAAAGCTCGATCCAGCCTTTACCCATCGATGCGTTGCCAGCTGGTCCGCGGAACTCGACGCTCGCCCCGGCACG
AGCGACCTCGGTGGTGTCCACGCTGAGTCCGGTTTCCAGTCGTACGGTGCTGCTACCGCCAGTCCGCGAGCTACCCCCGG
CGCAGCGGATCGCGTCCACACCGCGAGCGGAGGCTTCTCCAACGGTACCGGTTCTGCAGCGGGCTGCCGCCGCGATCGAA
CCTGCCCTCGCCGATAGTCGGATCGTCGTGCTCCTGGTCGGTACGGATGCCGGGCCGGGGCGATGGAGCGCTCGCGCTGA
CACGATCGTCATCGCTGCCCTCGATGTGGAGTCCGGGCGCGGCGGGCTGTTCGGGGTGCCTCGCAATCTGGTCGGACTCC
CCATTCCGCGAGAACTGGCGGACCTGTATCCGGACGGCTCTTGGCCAGGATTGGCCAACGCGCTGTATACGCTCGGGTTG
CAGCGAGCCGAGCGGTTCCCGAACGCCGTCGATCCGGGCGCGGCTGCACTCGCGCGCTCCCTGGAGCAGCTGATCGGCAT
GCCGATCGACTACAGTGTGGTGGTGGACATGGGTGGCTTCGTGCGCGTGGTGGACGCGCTGGGAGGCGTGACCATCGACG
TCCCACAGCCGGTCTCGACGTGGCTGTCGCCACCCCTGCCCGGTGAAGACTGGGTGTACTACGAGATCCCGGCCGGCCGG
CAGCATCTCGATGGACATGAAGCGCTCGCCTACGCACGCTCGCGCACGGGGACGAGCGACTACGACCGGATGCAACGCCA
GCGCTGCTTGCTCGGCGCGCTCTGGCGCCAAGCAGACTGGCCGACGGTGCTGTTTCGGTTACCGCAGCTGCTCGCCGCGG
TCGAAGGGGCTGTGCGCACCGATATTCCCCGCGAGGCATTGCCCCAGCTCGTCCAGATGGCACTCGGTGTACGCGCCGAG
GCGATCGTGACGCTCGGCTTCACTCCTCCACGGTATGTCGCTGGTTGGGCACCCGGTGGGTACCCGATTCCGGACCGTGA
CCGGATTCGAGATGCGATCGAGGACGCGCTCGCTGGGTCGGGCGAACCGGAACCGGAGACGCGTCTGGCGAGTAGCTGTT
CCTGGTCACCCTGA

Upstream 100 bases:

>100_bases
AAACCGGCATCGAGCACCGGCGAATACCGTGTGGGGCGTCACCGTCCTCGGTGCGGTATCATCGGACAATCCAGCGTGAC
TGCCCGAGCGGGGTGTCGGC

Downstream 100 bases:

>100_bases
TGGCGCCCCCCGGCGCGTGCTGTGTCGTCGGATGACGAGGAGGCCGGCCAGGCCTGCGAGCAGGAGCGAGAGACCGAGCA
GTACAGAGGGGCCTTCGCTG

Product: cell envelope-related transcriptional attenuator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 536

Protein sequence:

>537_residues
MPLSDADLERRPPRTSAIRALAGWRAAIAFITSVLWPGAGHWIAGRPWRGLALGVPPALALGFLLWQASQLPGWGVTWLL
RPSVLRGLMIGNIVLGSYRAVALLDLVRIALAGRSRSCAGKRGPYLVLAALLVGSVVTPHAAVGLVLTRWSRFLDTTFPA
AAESSIQPLPIDALPAGPRNSTLAPARATSVVSTLSPVSSRTVLLPPVRELPPAQRIASTPRAEASPTVPVLQRAAAAIE
PALADSRIVVLLVGTDAGPGRWSARADTIVIAALDVESGRGGLFGVPRNLVGLPIPRELADLYPDGSWPGLANALYTLGL
QRAERFPNAVDPGAAALARSLEQLIGMPIDYSVVVDMGGFVRVVDALGGVTIDVPQPVSTWLSPPLPGEDWVYYEIPAGR
QHLDGHEALAYARSRTGTSDYDRMQRQRCLLGALWRQADWPTVLFRLPQLLAAVEGAVRTDIPREALPQLVQMALGVRAE
AIVTLGFTPPRYVAGWAPGGYPIPDRDRIRDAIEDALAGSGEPEPETRLASSCSWSP

Sequences:

>Translated_537_residues
MPLSDADLERRPPRTSAIRALAGWRAAIAFITSVLWPGAGHWIAGRPWRGLALGVPPALALGFLLWQASQLPGWGVTWLL
RPSVLRGLMIGNIVLGSYRAVALLDLVRIALAGRSRSCAGKRGPYLVLAALLVGSVVTPHAAVGLVLTRWSRFLDTTFPA
AAESSIQPLPIDALPAGPRNSTLAPARATSVVSTLSPVSSRTVLLPPVRELPPAQRIASTPRAEASPTVPVLQRAAAAIE
PALADSRIVVLLVGTDAGPGRWSARADTIVIAALDVESGRGGLFGVPRNLVGLPIPRELADLYPDGSWPGLANALYTLGL
QRAERFPNAVDPGAAALARSLEQLIGMPIDYSVVVDMGGFVRVVDALGGVTIDVPQPVSTWLSPPLPGEDWVYYEIPAGR
QHLDGHEALAYARSRTGTSDYDRMQRQRCLLGALWRQADWPTVLFRLPQLLAAVEGAVRTDIPREALPQLVQMALGVRAE
AIVTLGFTPPRYVAGWAPGGYPIPDRDRIRDAIEDALAGSGEPEPETRLASSCSWSP
>Mature_536_residues
PLSDADLERRPPRTSAIRALAGWRAAIAFITSVLWPGAGHWIAGRPWRGLALGVPPALALGFLLWQASQLPGWGVTWLLR
PSVLRGLMIGNIVLGSYRAVALLDLVRIALAGRSRSCAGKRGPYLVLAALLVGSVVTPHAAVGLVLTRWSRFLDTTFPAA
AESSIQPLPIDALPAGPRNSTLAPARATSVVSTLSPVSSRTVLLPPVRELPPAQRIASTPRAEASPTVPVLQRAAAAIEP
ALADSRIVVLLVGTDAGPGRWSARADTIVIAALDVESGRGGLFGVPRNLVGLPIPRELADLYPDGSWPGLANALYTLGLQ
RAERFPNAVDPGAAALARSLEQLIGMPIDYSVVVDMGGFVRVVDALGGVTIDVPQPVSTWLSPPLPGEDWVYYEIPAGRQ
HLDGHEALAYARSRTGTSDYDRMQRQRCLLGALWRQADWPTVLFRLPQLLAAVEGAVRTDIPREALPQLVQMALGVRAEA
IVTLGFTPPRYVAGWAPGGYPIPDRDRIRDAIEDALAGSGEPEPETRLASSCSWSP

Specific function: Involved in sarA attenuation. Affects resistance to oxacillin and teicoplanin, as well as the synthesis of virulence factors [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 57188; Mature: 57056

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSDADLERRPPRTSAIRALAGWRAAIAFITSVLWPGAGHWIAGRPWRGLALGVPPALA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCHHHH
LGFLLWQASQLPGWGVTWLLRPSVLRGLMIGNIVLGSYRAVALLDLVRIALAGRSRSCAG
HHHHHHHHCCCCCCCHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KRGPYLVLAALLVGSVVTPHAAVGLVLTRWSRFLDTTFPAAAESSIQPLPIDALPAGPRN
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCC
STLAPARATSVVSTLSPVSSRTVLLPPVRELPPAQRIASTPRAEASPTVPVLQRAAAAIE
CCCCCHHHHHHHHHHCCCCCCEEECCCHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHH
PALADSRIVVLLVGTDAGPGRWSARADTIVIAALDVESGRGGLFGVPRNLVGLPIPRELA
HHCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHCCCCCCHHHH
DLYPDGSWPGLANALYTLGLQRAERFPNAVDPGAAALARSLEQLIGMPIDYSVVVDMGGF
HHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHH
VRVVDALGGVTIDVPQPVSTWLSPPLPGEDWVYYEIPAGRQHLDGHEALAYARSRTGTSD
HHHHHHHCCEEEECCCCHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCHH
YDRMQRQRCLLGALWRQADWPTVLFRLPQLLAAVEGAVRTDIPREALPQLVQMALGVRAE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEE
AIVTLGFTPPRYVAGWAPGGYPIPDRDRIRDAIEDALAGSGEPEPETRLASSCSWSP
EEEEECCCCCHHEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
PLSDADLERRPPRTSAIRALAGWRAAIAFITSVLWPGAGHWIAGRPWRGLALGVPPALA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCHHHH
LGFLLWQASQLPGWGVTWLLRPSVLRGLMIGNIVLGSYRAVALLDLVRIALAGRSRSCAG
HHHHHHHHCCCCCCCHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KRGPYLVLAALLVGSVVTPHAAVGLVLTRWSRFLDTTFPAAAESSIQPLPIDALPAGPRN
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCC
STLAPARATSVVSTLSPVSSRTVLLPPVRELPPAQRIASTPRAEASPTVPVLQRAAAAIE
CCCCCHHHHHHHHHHCCCCCCEEECCCHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHH
PALADSRIVVLLVGTDAGPGRWSARADTIVIAALDVESGRGGLFGVPRNLVGLPIPRELA
HHCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHCCCCCCHHHH
DLYPDGSWPGLANALYTLGLQRAERFPNAVDPGAAALARSLEQLIGMPIDYSVVVDMGGF
HHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHH
VRVVDALGGVTIDVPQPVSTWLSPPLPGEDWVYYEIPAGRQHLDGHEALAYARSRTGTSD
HHHHHHHCCEEEECCCCHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCHH
YDRMQRQRCLLGALWRQADWPTVLFRLPQLLAAVEGAVRTDIPREALPQLVQMALGVRAE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEE
AIVTLGFTPPRYVAGWAPGGYPIPDRDRIRDAIEDALAGSGEPEPETRLASSCSWSP
EEEEECCCCCHHEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12878519 [H]