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The map label for this gene is atpH

Identifier: 221633214

GI number: 221633214

Start: 1217845

End: 1218387

Strand: Reverse

Name: atpH

Synonym: trd_1231

Alternate gene names: 221633214

Gene position: 1218387-1217845 (Counterclockwise)

Preceding gene: 221633215

Following gene: 221633213

Centisome position: 60.83

GC content: 64.09

Gene sequence:

>543_bases
GTGGCGGTCGCAGGAGTCGCCAAGCGGTACGCCCAGGCTGCGTTCGCCGTCGCCAAGGAGCACGGCCAGCTGGACTTTTG
GGAGCAGCGATTAACTGATTTGGAGGCCCTGGCGCGAGACAGCGCGGTCGAGGAGTTCATCCAGAATCCAGCGATCCCAC
TGGAGGCCAAGGTCCAAGTGATCGATCGGCTTTTCCCCGGTGACGAGAACCGGTACGTGCGAAATCTCCTCGTGCTGCTC
CTGGAGCGGGGACGCTGGCACCAGCTGCGCGATGTCGTCGTGGCTTTCCGCGAGCTTCTGCGGGAGCATCGCGGGGTGAT
CGATGTCGAGCTGGTCACGGCGGTGCCACTGGAACCGAGCGAGGTGGAGCGACTCCGTCGCGAACTCGCGCAGCGACTGA
GTCGTCCGGTCGAGTTGCGCACGACGGTCGATCCCGAACTTCTCGGTGGTGTGGTGCTCAAGATCGGGGACGAAGTCTTC
GATGCCAGTGTGCGCACGCAGTTGACGAATCTCCGGCGGCAACTCGTCGGAGCAGCAGCCTGA

Upstream 100 bases:

>100_bases
CCCGTATCATTCGCCAGGAACTGGATCGCGATCGGCACCTGGCCTTGATCGAACAGGCGCTGGCTGAACTCGATGGCGCG
CGGCGGTAGGGGGTGCGAGC

Downstream 100 bases:

>100_bases
GCGCGTGAGGGAGGCAACATGTCAGTGCGTCCGACCGAAATCACGGAGATCCTCAAGCAACAGATCGAGCAATACGGTAG
TCGGATGGTCGTGACCAATG

Product: ATP synthase F1 subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MAVAGVAKRYAQAAFAVAKEHGQLDFWEQRLTDLEALARDSAVEEFIQNPAIPLEAKVQVIDRLFPGDENRYVRNLLVLL
LERGRWHQLRDVVVAFRELLREHRGVIDVELVTAVPLEPSEVERLRRELAQRLSRPVELRTTVDPELLGGVVLKIGDEVF
DASVRTQLTNLRRQLVGAAA

Sequences:

>Translated_180_residues
MAVAGVAKRYAQAAFAVAKEHGQLDFWEQRLTDLEALARDSAVEEFIQNPAIPLEAKVQVIDRLFPGDENRYVRNLLVLL
LERGRWHQLRDVVVAFRELLREHRGVIDVELVTAVPLEPSEVERLRRELAQRLSRPVELRTTVDPELLGGVVLKIGDEVF
DASVRTQLTNLRRQLVGAAA
>Mature_179_residues
AVAGVAKRYAQAAFAVAKEHGQLDFWEQRLTDLEALARDSAVEEFIQNPAIPLEAKVQVIDRLFPGDENRYVRNLLVLLL
ERGRWHQLRDVVVAFRELLREHRGVIDVELVTAVPLEPSEVERLRRELAQRLSRPVELRTTVDPELLGGVVLKIGDEVFD
ASVRTQLTNLRRQLVGAAA

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=176, Percent_Identity=28.9772727272727, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI1790173, Length=169, Percent_Identity=29.585798816568, Blast_Score=76, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71984710, Length=180, Percent_Identity=27.7777777777778, Blast_Score=79, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71984717, Length=180, Percent_Identity=27.7777777777778, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320504, Length=178, Percent_Identity=28.6516853932584, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24647054, Length=172, Percent_Identity=34.3023255813954, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24647056, Length=96, Percent_Identity=37.5, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_THERP (B9L1H2)

Other databases:

- EMBL:   CP001275
- RefSeq:   YP_002522439.1
- GeneID:   7355241
- GenomeReviews:   CP001275_GR
- KEGG:   tro:trd_1231
- OMA:   FIAICGE
- ProtClustDB:   CLSK2807913
- HAMAP:   MF_01416
- InterPro:   IPR000711
- InterPro:   IPR020781
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 20378; Mature: 20247

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVAGVAKRYAQAAFAVAKEHGQLDFWEQRLTDLEALARDSAVEEFIQNPAIPLEAKVQV
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IDRLFPGDENRYVRNLLVLLLERGRWHQLRDVVVAFRELLREHRGVIDVELVTAVPLEPS
HHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEHEECCCCHH
EVERLRRELAQRLSRPVELRTTVDPELLGGVVLKIGDEVFDASVRTQLTNLRRQLVGAAA
HHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVAGVAKRYAQAAFAVAKEHGQLDFWEQRLTDLEALARDSAVEEFIQNPAIPLEAKVQV
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IDRLFPGDENRYVRNLLVLLLERGRWHQLRDVVVAFRELLREHRGVIDVELVTAVPLEPS
HHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEHEECCCCHH
EVERLRRELAQRLSRPVELRTTVDPELLGGVVLKIGDEVFDASVRTQLTNLRRQLVGAAA
HHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA