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The map label for this gene is atpA

Identifier: 221633213

GI number: 221633213

Start: 1216294

End: 1217826

Strand: Reverse

Name: atpA

Synonym: trd_1230

Alternate gene names: 221633213

Gene position: 1217826-1216294 (Counterclockwise)

Preceding gene: 221633214

Following gene: 221633212

Centisome position: 60.8

GC content: 61.51

Gene sequence:

>1533_bases
ATGTCAGTGCGTCCGACCGAAATCACGGAGATCCTCAAGCAACAGATCGAGCAATACGGTAGTCGGATGGTCGTGACCAA
TGTCGGCTACGTGGTCCAAGTGGGTGACGGGATCGCGACTGTCCATGGCCTGCGTGATGTGATGGCCAGCGAGCTCGTCG
AGTTCGAGAACGGTGTGCTCGGCATCGCCTTCAACCTCCAAGAGGACTCGGTCGGTGTCATCATCCTCGGCGACTACACG
GGCATCGAGGAAGGTGACGAGGTGCGAGCGACCGGCCGCATCGCGTCGGTACCGGTCGGGCCAGCACTGGTCGGCCGGGT
GGTCAATGCGCTCGGTGAACCGATCGACGGGAAGGGGCCGATCAACACCGACAAGTTCCGCCCGATCGAGCGGATCGCTC
CCGGCGTGGTGATGCGTCAAGATGTGGACACAGCACTGCAGACCGGCATCAAGGCCATCGACTCGATGATCCCGATTGGC
CGGGGGCAGCGCGAGCTGATCATCGGTGACCGGCAGACGGGGAAGACAGCGATCGCCATCGATACCATCATCAATCAGAA
GGGGAAAGGTGTCATCTGCATCTACGTGGCGATCGGTCAGAAGCGTGCGCAAGTCGCACAGACTGTGGCGACGCTCGAGC
GGTACGGCGCGATGGAGCATACGATCGTCGTGGCTGCGACCGCATCGGATCCGGCAGCACTACAGTACATCGCCCCGTAC
GCCGGTTGTGCGATGGGCGAAGAGATCATGGAAAGCGGTGGCCATGCCCTGATCGTCTACGATGACCTGTCCAAGCATGC
CTGGGCGTATCGGCAGGTTTCCCTGCTGATGCGGCGGCCACCGGGCCGAGAAGCGTATCCTGGCGATATCTTCTACCTCC
ATTCGCGCCTCCTCGAGCGTGCTGCGCGACTTCGAGACGATCTGGGGGGTGGAACACTGACCGCTCTGCCGATCGTCGAG
ACGCAAGCCAACGACGTCTCGGCCTACATTCCGACGAACGTCATCTCGATCACGGATGGTCAGATCTATCTGGAGCCGGA
TCTGTTCTATGCCGGTATCCGGCCCGCGATCAACGTGGGTCTCTCGGTTTCGCGCGTCGGTGGCGCAGCACAGATCCGCG
CGATGCGACAAGTGGCCGGGCGCTTGCGTCTGGAATTGGCGCAGTTCCGGGAACTCGCAGCGTTCGCGCAATTTGCGGCC
GAATTGGACCCAGCGACCAAGCGCCAGATCGATCGCGGTTTGCGCCTGACCGAGGTGCTCAAACAGCCGCAGTACGAACC
GATGCCGGTCGAGGAGCAGGTGGCGATCATCTGGGTCGCGACGAACGGCTACCTGGATGACGTACTGGTCGAGCATGTGC
GCGAGTTCGAGAAGCAGTATCTCGACTACCTGCGGACGAGTCATCCGCAGATTCTGCAGCGGATCGCCAGTGAGCGTGAG
CTCAAGGACGATCTGATTCAACAACTGCACGAGGTCACGCGAGCCTTCAAGCAGAGTATTTGGGCGCCGCCGCAGGAGCG
GGTGATCATCTGA

Upstream 100 bases:

>100_bases
GATCGGGGACGAAGTCTTCGATGCCAGTGTGCGCACGCAGTTGACGAATCTCCGGCGGCAACTCGTCGGAGCAGCAGCCT
GAGCGCGTGAGGGAGGCAAC

Downstream 100 bases:

>100_bases
CCAGCTGGAGGGGGCGAAGGCCGTGCCGCAAGCAGTAACGCCGCGCGAGATCAGGCGCCGGATCCGGAGCATCAAGAATA
CGGCGCAGATCACCCGCGCC

Product: ATP synthase F1 subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MSVRPTEITEILKQQIEQYGSRMVVTNVGYVVQVGDGIATVHGLRDVMASELVEFENGVLGIAFNLQEDSVGVIILGDYT
GIEEGDEVRATGRIASVPVGPALVGRVVNALGEPIDGKGPINTDKFRPIERIAPGVVMRQDVDTALQTGIKAIDSMIPIG
RGQRELIIGDRQTGKTAIAIDTIINQKGKGVICIYVAIGQKRAQVAQTVATLERYGAMEHTIVVAATASDPAALQYIAPY
AGCAMGEEIMESGGHALIVYDDLSKHAWAYRQVSLLMRRPPGREAYPGDIFYLHSRLLERAARLRDDLGGGTLTALPIVE
TQANDVSAYIPTNVISITDGQIYLEPDLFYAGIRPAINVGLSVSRVGGAAQIRAMRQVAGRLRLELAQFRELAAFAQFAA
ELDPATKRQIDRGLRLTEVLKQPQYEPMPVEEQVAIIWVATNGYLDDVLVEHVREFEKQYLDYLRTSHPQILQRIASERE
LKDDLIQQLHEVTRAFKQSIWAPPQERVII

Sequences:

>Translated_510_residues
MSVRPTEITEILKQQIEQYGSRMVVTNVGYVVQVGDGIATVHGLRDVMASELVEFENGVLGIAFNLQEDSVGVIILGDYT
GIEEGDEVRATGRIASVPVGPALVGRVVNALGEPIDGKGPINTDKFRPIERIAPGVVMRQDVDTALQTGIKAIDSMIPIG
RGQRELIIGDRQTGKTAIAIDTIINQKGKGVICIYVAIGQKRAQVAQTVATLERYGAMEHTIVVAATASDPAALQYIAPY
AGCAMGEEIMESGGHALIVYDDLSKHAWAYRQVSLLMRRPPGREAYPGDIFYLHSRLLERAARLRDDLGGGTLTALPIVE
TQANDVSAYIPTNVISITDGQIYLEPDLFYAGIRPAINVGLSVSRVGGAAQIRAMRQVAGRLRLELAQFRELAAFAQFAA
ELDPATKRQIDRGLRLTEVLKQPQYEPMPVEEQVAIIWVATNGYLDDVLVEHVREFEKQYLDYLRTSHPQILQRIASERE
LKDDLIQQLHEVTRAFKQSIWAPPQERVII
>Mature_509_residues
SVRPTEITEILKQQIEQYGSRMVVTNVGYVVQVGDGIATVHGLRDVMASELVEFENGVLGIAFNLQEDSVGVIILGDYTG
IEEGDEVRATGRIASVPVGPALVGRVVNALGEPIDGKGPINTDKFRPIERIAPGVVMRQDVDTALQTGIKAIDSMIPIGR
GQRELIIGDRQTGKTAIAIDTIINQKGKGVICIYVAIGQKRAQVAQTVATLERYGAMEHTIVVAATASDPAALQYIAPYA
GCAMGEEIMESGGHALIVYDDLSKHAWAYRQVSLLMRRPPGREAYPGDIFYLHSRLLERAARLRDDLGGGTLTALPIVET
QANDVSAYIPTNVISITDGQIYLEPDLFYAGIRPAINVGLSVSRVGGAAQIRAMRQVAGRLRLELAQFRELAAFAQFAAE
LDPATKRQIDRGLRLTEVLKQPQYEPMPVEEQVAIIWVATNGYLDDVLVEHVREFEKQYLDYLRTSHPQILQRIASEREL
KDDLIQQLHEVTRAFKQSIWAPPQERVII

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=498, Percent_Identity=59.0361445783133, Blast_Score=595, Evalue=1e-170,
Organism=Homo sapiens, GI4757810, Length=498, Percent_Identity=59.0361445783133, Blast_Score=595, Evalue=1e-170,
Organism=Homo sapiens, GI19913426, Length=302, Percent_Identity=30.4635761589404, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI19913428, Length=303, Percent_Identity=29.3729372937294, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI32189394, Length=316, Percent_Identity=25.3164556962025, Blast_Score=99, Evalue=8e-21,
Organism=Escherichia coli, GI1790172, Length=510, Percent_Identity=55.8823529411765, Blast_Score=577, Evalue=1e-166,
Organism=Escherichia coli, GI1788251, Length=399, Percent_Identity=26.3157894736842, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1790170, Length=347, Percent_Identity=25.0720461095101, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71988063, Length=499, Percent_Identity=58.7174348697395, Blast_Score=599, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI71988080, Length=499, Percent_Identity=58.7174348697395, Blast_Score=598, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI71988074, Length=499, Percent_Identity=54.9098196392786, Blast_Score=550, Evalue=1e-157,
Organism=Caenorhabditis elegans, GI17510931, Length=390, Percent_Identity=27.9487179487179, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17570191, Length=334, Percent_Identity=29.6407185628743, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=316, Percent_Identity=23.7341772151899, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=62, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71988068, Length=73, Percent_Identity=39.7260273972603, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=501, Percent_Identity=56.4870259481038, Blast_Score=586, Evalue=1e-168,
Organism=Saccharomyces cerevisiae, GI6319603, Length=306, Percent_Identity=29.4117647058824, Blast_Score=110, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6322581, Length=376, Percent_Identity=25.7978723404255, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24658560, Length=502, Percent_Identity=58.3665338645418, Blast_Score=591, Evalue=1e-169,
Organism=Drosophila melanogaster, GI281361666, Length=302, Percent_Identity=29.1390728476821, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24646341, Length=302, Percent_Identity=29.1390728476821, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17136796, Length=302, Percent_Identity=29.1390728476821, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24638766, Length=316, Percent_Identity=25.3164556962025, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI28574560, Length=428, Percent_Identity=24.7663551401869, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_THERP (B9L1H1)

Other databases:

- EMBL:   CP001275
- RefSeq:   YP_002522438.1
- GeneID:   7355528
- GenomeReviews:   CP001275_GR
- KEGG:   tro:trd_1230
- OMA:   EFEDKML
- ProtClustDB:   CLSK2807912
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 56052; Mature: 55921

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRPTEITEILKQQIEQYGSRMVVTNVGYVVQVGDGIATVHGLRDVMASELVEFENGVL
CCCCHHHHHHHHHHHHHHHCCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEE
GIAFNLQEDSVGVIILGDYTGIEEGDEVRATGRIASVPVGPALVGRVVNALGEPIDGKGP
EEEEEECCCCEEEEEEECCCCCCCCCCEEECCCEEECCCCHHHHHHHHHHHCCCCCCCCC
INTDKFRPIERIAPGVVMRQDVDTALQTGIKAIDSMIPIGRGQRELIIGDRQTGKTAIAI
CCCCCCCCHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEE
DTIINQKGKGVICIYVAIGQKRAQVAQTVATLERYGAMEHTIVVAATASDPAALQYIAPY
EHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHH
AGCAMGEEIMESGGHALIVYDDLSKHAWAYRQVSLLMRRPPGREAYPGDIFYLHSRLLER
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARLRDDLGGGTLTALPIVETQANDVSAYIPTNVISITDGQIYLEPDLFYAGIRPAINVG
HHHHHHHCCCCEEEEEEEEECCCCCEEEECCCCEEEEECCEEEECCCCEECCCCHHHHCC
LSVSRVGGAAQIRAMRQVAGRLRLELAQFRELAAFAQFAAELDPATKRQIDRGLRLTEVL
EEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHH
KQPQYEPMPVEEQVAIIWVATNGYLDDVLVEHVREFEKQYLDYLRTSHPQILQRIASERE
HCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LKDDLIQQLHEVTRAFKQSIWAPPQERVII
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SVRPTEITEILKQQIEQYGSRMVVTNVGYVVQVGDGIATVHGLRDVMASELVEFENGVL
CCCHHHHHHHHHHHHHHHCCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEE
GIAFNLQEDSVGVIILGDYTGIEEGDEVRATGRIASVPVGPALVGRVVNALGEPIDGKGP
EEEEEECCCCEEEEEEECCCCCCCCCCEEECCCEEECCCCHHHHHHHHHHHCCCCCCCCC
INTDKFRPIERIAPGVVMRQDVDTALQTGIKAIDSMIPIGRGQRELIIGDRQTGKTAIAI
CCCCCCCCHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEE
DTIINQKGKGVICIYVAIGQKRAQVAQTVATLERYGAMEHTIVVAATASDPAALQYIAPY
EHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHH
AGCAMGEEIMESGGHALIVYDDLSKHAWAYRQVSLLMRRPPGREAYPGDIFYLHSRLLER
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARLRDDLGGGTLTALPIVETQANDVSAYIPTNVISITDGQIYLEPDLFYAGIRPAINVG
HHHHHHHCCCCEEEEEEEEECCCCCEEEECCCCEEEEECCEEEECCCCEECCCCHHHHCC
LSVSRVGGAAQIRAMRQVAGRLRLELAQFRELAAFAQFAAELDPATKRQIDRGLRLTEVL
EEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHH
KQPQYEPMPVEEQVAIIWVATNGYLDDVLVEHVREFEKQYLDYLRTSHPQILQRIASERE
HCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LKDDLIQQLHEVTRAFKQSIWAPPQERVII
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA