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The map label for this gene is ccmF [H]

Identifier: 221633205

GI number: 221633205

Start: 1208569

End: 1210554

Strand: Reverse

Name: ccmF [H]

Synonym: trd_1222

Alternate gene names: 221633205

Gene position: 1210554-1208569 (Counterclockwise)

Preceding gene: 221633206

Following gene: 221633204

Centisome position: 60.44

GC content: 62.29

Gene sequence:

>1986_bases
GTGGCACAGCTGGGTTCGGGAGCGCTGGTCCTCGCTCTCCTCTTGGCAGTGTACGGTCTCGGAGCGAGCTTCATCGGGGT
GCGACGGCGCGTGCCGGAACTCCTGGCGAGCGCCTACCGAGCGACCTACGGCGTGGCTTTCCTGATTCTCGTCGCCCTCA
TCGTCTTGGTCATTTCGTTCGTGCGACACGATTTTCGTCTCGCTTACGTGGCAGCGCGTTCCAGCCGCGACATGCCGATC
CAGTATGTCATTTCAGCGTTCTACGGGGGACAGGAGGGTAGCCTCCTCTATTGGGCCGCAGTCGCGAGCGGCTTGGGGGC
ACTCGCGCTGTATCTCCACCGCCGTTCCGATCGTGCACTGCTTCCGTACATGACGATGACCCTTTTGGCCATCGTCACGT
TTTTCCTCCTTGTCCTGACGATCGTCGCCAGTCCCTTCCGGCTGCTTCCGGTCACCCCACCCGATGGGGCGGGACTCAAC
CCGCTGCTCCGCGATCCAGGAATGATGGCGCACCCGCCGTTCCTGCTGGCAGGGTATGCGAGTTTCACCGTGCCCTTCGC
TTTCGGCATGGCGGCACTGGTGACCGGACGGCTCGGCAGCGATTGGCTGCAGGCCATTCGGCGCTGGACGCTCCTGGCCT
GGGCGCTCCTCGGCATGGGTCTCTTGATCGGGGCGTGGTGGGCCTACCATGTGCTCGGTTGGGGAGGCTACTGGGGGTGG
GATCCGGTCGAGAATCTGGCCCTGTTGCCGTGGTTGACGGCAACAGCGTTCTTGCACTCGGTGATCGTTCAAGAGCGGCG
GGGGATGCTCAAGGTCTGGAACCTCGCCTTGCTCTTGGCGACGTTCGCGTTGTGCATCTTCGGTACGTTTATCGTGCGCA
GCGGCATGCTGTCGTCCGTCCACGCTTTTGCCGTCTCGACGATCGGTCACTGGTTCTTGGCGTATTTGGCTCTCGTCCTC
GTCGTGGGGATCGGATTGCTGCTCTATCGGCTACCGGGGTTGCAGAGCGAGCGGCACATCGAGTCGGTGACGTCGCGCGA
GGGCGGCTTCCTCGTGAACAATTTGCTGCTGACCGCGATGGCCTTCGCGGTGTTTTGGGGAACGACTTTCCCATTGTTCA
GCGAGCTGTTCTGGGAAACTCGCATTACGGTCGGGCCGCCCTTCTATAACCGCGTCGTCGGGCCTCTGCTTCTCGTTTTG
CTCGCATTGATGGGGCTGGGACCGCTCCTGGCCTGGCGACGGACGGAACTTCCTTTGTTGCTCCGCAATCTGCGCTGGCC
GCTCCTCGCTGCGGGAGTCGCCGCCGGATTCGGTGTCATTCTGCTCGACCGCTGGTGGGCCGTGGCCGCCTACGCCGTCA
CAGTGTTCGCCTTTGCCGCCACGATCCAGGAGTACTGGCGAGGTGTTCGAGCACGACGCCGCAATGTCCGCGAGGCTCTC
CCGGTAGCTGCGTGGGAGCTACTGCGTCGGAACAACCGTCGCTACGGTGGGTATCTGGTTCATCTGGCGATTCTTCTGAT
GGCGGTCGGTATCATTGCCTCCAATGCCTTCCAGCTGGAGCGCCAATTCGTTTTGCGCCCTGGTGAGCAGGGTTCCATCG
GACCGTACACGATCGTCTACCGCGGCCTGGACGATCGGCGGACAGCAGACGCGGAAGTCGTCGCTGCCAAAGTCGATGTC
TATCGTGGCGAGCGCTACGCCGCGACAGTCGAAAGTTATCGATTCTTTTATCGCAACTACGAGGATCAACCGACTGCCCG
CATGGGAATCACACTTGTGGGCCTCGATGACGTGTACGTGGTACTCGACCGCTGGCAGGATGACGGAACTGCGAGCATCC
GGGTTTATGTGAATCCGCTGGTGATCTGGATCTGGGTCGGTGGAGCAGTATTCGTCCTTGGTACGCTTACGCTGTTCTGG
CCGCAGCCGGTTCCCGCGCCGGCTCGCCTGCCGCGTACCGTTCCGGGTATGGCACGCGAGGCATAG

Upstream 100 bases:

>100_bases
AACGGGCAACCCGTGCAGGCAGACAGCGTCCTAACGCAGTGCCCGTCTCGTTTCGAGGCAGCTCCGACTGCCTCCTCGAG
TTGAGAACGGAGGCTTTCTC

Downstream 100 bases:

>100_bases
CATGACTGCGCGAGGGTGGCGAGCACGAGTTCGAAGGTGGCGAGTGACTCGGCTGGGTGCACGGGTGAGTCAGCTCGTTC
CGGGGTTCGTCATCGTGGTT

Product: cytochrome C-type biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 660

Protein sequence:

>661_residues
MAQLGSGALVLALLLAVYGLGASFIGVRRRVPELLASAYRATYGVAFLILVALIVLVISFVRHDFRLAYVAARSSRDMPI
QYVISAFYGGQEGSLLYWAAVASGLGALALYLHRRSDRALLPYMTMTLLAIVTFFLLVLTIVASPFRLLPVTPPDGAGLN
PLLRDPGMMAHPPFLLAGYASFTVPFAFGMAALVTGRLGSDWLQAIRRWTLLAWALLGMGLLIGAWWAYHVLGWGGYWGW
DPVENLALLPWLTATAFLHSVIVQERRGMLKVWNLALLLATFALCIFGTFIVRSGMLSSVHAFAVSTIGHWFLAYLALVL
VVGIGLLLYRLPGLQSERHIESVTSREGGFLVNNLLLTAMAFAVFWGTTFPLFSELFWETRITVGPPFYNRVVGPLLLVL
LALMGLGPLLAWRRTELPLLLRNLRWPLLAAGVAAGFGVILLDRWWAVAAYAVTVFAFAATIQEYWRGVRARRRNVREAL
PVAAWELLRRNNRRYGGYLVHLAILLMAVGIIASNAFQLERQFVLRPGEQGSIGPYTIVYRGLDDRRTADAEVVAAKVDV
YRGERYAATVESYRFFYRNYEDQPTARMGITLVGLDDVYVVLDRWQDDGTASIRVYVNPLVIWIWVGGAVFVLGTLTLFW
PQPVPAPARLPRTVPGMAREA

Sequences:

>Translated_661_residues
MAQLGSGALVLALLLAVYGLGASFIGVRRRVPELLASAYRATYGVAFLILVALIVLVISFVRHDFRLAYVAARSSRDMPI
QYVISAFYGGQEGSLLYWAAVASGLGALALYLHRRSDRALLPYMTMTLLAIVTFFLLVLTIVASPFRLLPVTPPDGAGLN
PLLRDPGMMAHPPFLLAGYASFTVPFAFGMAALVTGRLGSDWLQAIRRWTLLAWALLGMGLLIGAWWAYHVLGWGGYWGW
DPVENLALLPWLTATAFLHSVIVQERRGMLKVWNLALLLATFALCIFGTFIVRSGMLSSVHAFAVSTIGHWFLAYLALVL
VVGIGLLLYRLPGLQSERHIESVTSREGGFLVNNLLLTAMAFAVFWGTTFPLFSELFWETRITVGPPFYNRVVGPLLLVL
LALMGLGPLLAWRRTELPLLLRNLRWPLLAAGVAAGFGVILLDRWWAVAAYAVTVFAFAATIQEYWRGVRARRRNVREAL
PVAAWELLRRNNRRYGGYLVHLAILLMAVGIIASNAFQLERQFVLRPGEQGSIGPYTIVYRGLDDRRTADAEVVAAKVDV
YRGERYAATVESYRFFYRNYEDQPTARMGITLVGLDDVYVVLDRWQDDGTASIRVYVNPLVIWIWVGGAVFVLGTLTLFW
PQPVPAPARLPRTVPGMAREA
>Mature_660_residues
AQLGSGALVLALLLAVYGLGASFIGVRRRVPELLASAYRATYGVAFLILVALIVLVISFVRHDFRLAYVAARSSRDMPIQ
YVISAFYGGQEGSLLYWAAVASGLGALALYLHRRSDRALLPYMTMTLLAIVTFFLLVLTIVASPFRLLPVTPPDGAGLNP
LLRDPGMMAHPPFLLAGYASFTVPFAFGMAALVTGRLGSDWLQAIRRWTLLAWALLGMGLLIGAWWAYHVLGWGGYWGWD
PVENLALLPWLTATAFLHSVIVQERRGMLKVWNLALLLATFALCIFGTFIVRSGMLSSVHAFAVSTIGHWFLAYLALVLV
VGIGLLLYRLPGLQSERHIESVTSREGGFLVNNLLLTAMAFAVFWGTTFPLFSELFWETRITVGPPFYNRVVGPLLLVLL
ALMGLGPLLAWRRTELPLLLRNLRWPLLAAGVAAGFGVILLDRWWAVAAYAVTVFAFAATIQEYWRGVRARRRNVREALP
VAAWELLRRNNRRYGGYLVHLAILLMAVGIIASNAFQLERQFVLRPGEQGSIGPYTIVYRGLDDRRTADAEVVAAKVDVY
RGERYAATVESYRFFYRNYEDQPTARMGITLVGLDDVYVVLDRWQDDGTASIRVYVNPLVIWIWVGGAVFVLGTLTLFWP
QPVPAPARLPRTVPGMAREA

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=656, Percent_Identity=34.7560975609756, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI1790511, Length=414, Percent_Identity=35.7487922705314, Blast_Score=207, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 73351; Mature: 73219

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLGSGALVLALLLAVYGLGASFIGVRRRVPELLASAYRATYGVAFLILVALIVLVISF
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRHDFRLAYVAARSSRDMPIQYVISAFYGGQEGSLLYWAAVASGLGALALYLHRRSDRAL
HHHHHHHHEEEECCCCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCH
LPYMTMTLLAIVTFFLLVLTIVASPFRLLPVTPPDGAGLNPLLRDPGMMAHPPFLLAGYA
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHCCCCCCCCCCHHHHHHH
SFTVPFAFGMAALVTGRLGSDWLQAIRRWTLLAWALLGMGLLIGAWWAYHVLGWGGYWGW
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DPVENLALLPWLTATAFLHSVIVQERRGMLKVWNLALLLATFALCIFGTFIVRSGMLSSV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAFAVSTIGHWFLAYLALVLVVGIGLLLYRLPGLQSERHIESVTSREGGFLVNNLLLTAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHH
AFAVFWGTTFPLFSELFWETRITVGPPFYNRVVGPLLLVLLALMGLGPLLAWRRTELPLL
HHHHHHCCHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHH
LRNLRWPLLAAGVAAGFGVILLDRWWAVAAYAVTVFAFAATIQEYWRGVRARRRNVREAL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PVAAWELLRRNNRRYGGYLVHLAILLMAVGIIASNAFQLERQFVLRPGEQGSIGPYTIVY
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEE
RGLDDRRTADAEVVAAKVDVYRGERYAATVESYRFFYRNYEDQPTARMGITLVGLDDVYV
ECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHCEEEEECCHHEE
VLDRWQDDGTASIRVYVNPLVIWIWVGGAVFVLGTLTLFWPQPVPAPARLPRTVPGMARE
EEECCCCCCCEEEEEEECCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
A
C
>Mature Secondary Structure 
AQLGSGALVLALLLAVYGLGASFIGVRRRVPELLASAYRATYGVAFLILVALIVLVISF
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRHDFRLAYVAARSSRDMPIQYVISAFYGGQEGSLLYWAAVASGLGALALYLHRRSDRAL
HHHHHHHHEEEECCCCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCH
LPYMTMTLLAIVTFFLLVLTIVASPFRLLPVTPPDGAGLNPLLRDPGMMAHPPFLLAGYA
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHCCCCCCCCCCHHHHHHH
SFTVPFAFGMAALVTGRLGSDWLQAIRRWTLLAWALLGMGLLIGAWWAYHVLGWGGYWGW
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DPVENLALLPWLTATAFLHSVIVQERRGMLKVWNLALLLATFALCIFGTFIVRSGMLSSV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAFAVSTIGHWFLAYLALVLVVGIGLLLYRLPGLQSERHIESVTSREGGFLVNNLLLTAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHH
AFAVFWGTTFPLFSELFWETRITVGPPFYNRVVGPLLLVLLALMGLGPLLAWRRTELPLL
HHHHHHCCHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHH
LRNLRWPLLAAGVAAGFGVILLDRWWAVAAYAVTVFAFAATIQEYWRGVRARRRNVREAL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PVAAWELLRRNNRRYGGYLVHLAILLMAVGIIASNAFQLERQFVLRPGEQGSIGPYTIVY
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEE
RGLDDRRTADAEVVAAKVDVYRGERYAATVESYRFFYRNYEDQPTARMGITLVGLDDVYV
ECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHCEEEEECCHHEE
VLDRWQDDGTASIRVYVNPLVIWIWVGGAVFVLGTLTLFWPQPVPAPARLPRTVPGMARE
EEECCCCCCCEEEEEEECCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]