Click here to switch to the map view.

The map label for this gene is ccmC [H]

Identifier: 221633200

GI number: 221633200

Start: 1205498

End: 1206217

Strand: Reverse

Name: ccmC [H]

Synonym: trd_1217

Alternate gene names: 221633200

Gene position: 1206217-1205498 (Counterclockwise)

Preceding gene: 221633201

Following gene: 221633199

Centisome position: 60.22

GC content: 58.75

Gene sequence:

>720_bases
ATGGCGACAGTCACGAACACAGTCAGGCGACCAGCGACCACTGCATGGTTGTCGGTTCTCGCGGCGCTTTCCTTCTTGTC
GGTCGCCCTATCGGTCGTGCTGATCTTCCTGTATGCGCCGCGTGACGTCGATCAGGGCGAGGTGCAACGCTTGTTCTACC
TCCATCTGCCAGCTGCCTGGTTGGCCTATCTCTCCTTTTTCATCATCTTCGTCAGCAGCATCTTGTACCTGGTACGGGGG
CATGCCCGTTGGGATCGGCTGGCTCGCTCTGCGGCAGAACTCGGCTTCATTTTCACCACGCTCGTGTTGTTGACCGGTTC
GATCTGGGGGCGACCGATTTGGGGCACATGGTGGACGTGGGATGCGCGACTCACGACGACCCTGATCCTGTGGTTCATCT
ACCTCGGCTATTTCCTTTTGCGCGCGTATGTTGCAGATCCGGAGCGGGGGGCACGGTATGCCGCTGTTCTGGGAATCGTC
GGCTTCGTCGATATTCCGATCATTCACATGTCGGTTCGCTGGTGGCGCACGTTGCATCCCCAACCGATCGTGGTGAGGAG
CGAGGGACCGGCCATGCCGCCGGAGATGCTGGTGACGATGATCGTCACATTGGTTGCCTTCTGCATTCTCTACGTGTTCT
TGCTCGCGGTGAAATACCGGATCGAAACGACGCGTGATGAAGTGATGGAGCTCCGCGGGACGCTCGAACAGTACGGCTGA

Upstream 100 bases:

>100_bases
GGGGGCTTCGCCGCATTGTTCTTCGCGCTCGGTGCACTGACCTTCGGGAGCGTGACCGAAGAGTGAACGAATCGGCTCGA
AAGGAGAAAGGAGAGTGAGC

Downstream 100 bases:

>100_bases
TCGAGAAAGGGAGGAAGCGGAACGATGGAAAATGTGTGGTACCTGTTCGCTGGTTTCTTCGTGACCTGGTTGATTCTCGG
CATCTACCTGTTCTCGTTGC

Product: heme exporter protein C

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmC [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MATVTNTVRRPATTAWLSVLAALSFLSVALSVVLIFLYAPRDVDQGEVQRLFYLHLPAAWLAYLSFFIIFVSSILYLVRG
HARWDRLARSAAELGFIFTTLVLLTGSIWGRPIWGTWWTWDARLTTTLILWFIYLGYFLLRAYVADPERGARYAAVLGIV
GFVDIPIIHMSVRWWRTLHPQPIVVRSEGPAMPPEMLVTMIVTLVAFCILYVFLLAVKYRIETTRDEVMELRGTLEQYG

Sequences:

>Translated_239_residues
MATVTNTVRRPATTAWLSVLAALSFLSVALSVVLIFLYAPRDVDQGEVQRLFYLHLPAAWLAYLSFFIIFVSSILYLVRG
HARWDRLARSAAELGFIFTTLVLLTGSIWGRPIWGTWWTWDARLTTTLILWFIYLGYFLLRAYVADPERGARYAAVLGIV
GFVDIPIIHMSVRWWRTLHPQPIVVRSEGPAMPPEMLVTMIVTLVAFCILYVFLLAVKYRIETTRDEVMELRGTLEQYG
>Mature_238_residues
ATVTNTVRRPATTAWLSVLAALSFLSVALSVVLIFLYAPRDVDQGEVQRLFYLHLPAAWLAYLSFFIIFVSSILYLVRGH
ARWDRLARSAAELGFIFTTLVLLTGSIWGRPIWGTWWTWDARLTTTLILWFIYLGYFLLRAYVADPERGARYAAVLGIVG
FVDIPIIHMSVRWWRTLHPQPIVVRSEGPAMPPEMLVTMIVTLVAFCILYVFLLAVKYRIETTRDEVMELRGTLEQYG

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=201, Percent_Identity=35.8208955223881, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 27378; Mature: 27247

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVTNTVRRPATTAWLSVLAALSFLSVALSVVLIFLYAPRDVDQGEVQRLFYLHLPAAW
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LAYLSFFIIFVSSILYLVRGHARWDRLARSAAELGFIFTTLVLLTGSIWGRPIWGTWWTW
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
DARLTTTLILWFIYLGYFLLRAYVADPERGARYAAVLGIVGFVDIPIIHMSVRWWRTLHP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QPIVVRSEGPAMPPEMLVTMIVTLVAFCILYVFLLAVKYRIETTRDEVMELRGTLEQYG
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATVTNTVRRPATTAWLSVLAALSFLSVALSVVLIFLYAPRDVDQGEVQRLFYLHLPAAW
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LAYLSFFIIFVSSILYLVRGHARWDRLARSAAELGFIFTTLVLLTGSIWGRPIWGTWWTW
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
DARLTTTLILWFIYLGYFLLRAYVADPERGARYAAVLGIVGFVDIPIIHMSVRWWRTLHP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QPIVVRSEGPAMPPEMLVTMIVTLVAFCILYVFLLAVKYRIETTRDEVMELRGTLEQYG
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]