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The map label for this gene is 221633052

Identifier: 221633052

GI number: 221633052

Start: 1042859

End: 1043824

Strand: Reverse

Name: 221633052

Synonym: trd_1068

Alternate gene names: NA

Gene position: 1043824-1042859 (Counterclockwise)

Preceding gene: 221633053

Following gene: 221633048

Centisome position: 52.11

GC content: 62.42

Gene sequence:

>966_bases
GTGGACTGGGGTCCAATCATCGATGGGCACAGCGATTTTGTCCTCTCTCTCCTCGAGACCGGTCGAGACTTTCTCGTCGA
AAGTCACGAAGGGCACGTCGATCTGCCGCGTGCCCAACGCGGGCGCCTGGGTGCGATGCTGAGCGCTGTCTTCGTTCGCA
ACGAGTATCTACCGGCGCAAGCGCTGGCCAGAACGATGCGCGGCGTGGATCGCCTACGGGCGACCGTCGCTCGCTCTCGC
GGTGCGATGGAAATCGTGACCGACGTCGACCAACTCGAGCGGTGCTTGGATCGGGGCGTTTTCGGCGCGATTCTGCACTT
CGAGGGTGCAGAGGCGATCGATGCCGAGTTCGCGGTTCTCCGACTGAGCTACGACCTTGGCTTGCGTTCGCTCGGGCTCA
CCTGGAGTCGTCCGAACATATTCGCCGAGGGTGTCGGTCCGGAGAATCGCGGAGGTGGGCTCACCAAGCTGGGGCGCGAG
TTGGTCTGTGCGTGTAACGAGATGGGGATCCTGATCGATGTCTCGCATCTCAACGATGCTGGCTTCTGGGACGTGCTGGA
AGAATCGACGCGACCGGTGGTCGCAAGTCACAGCAATTGTCGCGCGCTTTGTGCTGTGGAACGCAATCTGACCGATGACC
AAATCCGAGCCCTCGCTGAGAAAGACGGCCTCGTGGGGATCAACTTCCACGTGGGCTTCATCCGCGAAGGAGCCGAGCGA
CCCAGCGATGTGACGCTGGACGATGTGATCGCGCATATCGACCACATCGTTCAGCTCGTCGGGGTCGATCACGTCGGGTT
CGGCTCGGATTTCGATGGTGCCACGATGCCCGCTGAACTCGCGGATGCCGCCCAGCTGCCTCGACTGGTCGAGGCGCTGG
CACGACACGGCTACGACGAGCAGGCGCTCCGCAAAATCTCTCGCGACAACTGGCTGCGCGTGTTCCGCGCCGTGTGGCGA
TCGTAG

Upstream 100 bases:

>100_bases
GCTGGGCTGCATGTCACAGCGTCCAAGCCGAAGATGCTGGAGGGTGCTCGGGCTGGTGAAGCACAGGTGGTCGGCCGAGC
GATGCCGTGAGGAGGTTCTC

Downstream 100 bases:

>100_bases
CGCCATCAGTCGCCGCTTATCAGACGTCCGTCACGAGTTCGAGCGACTTTTCCGCGACCAAGCGCTGAACCATCGTGATG
AAGCGCTCGATCGACATCGA

Product: renal dipeptidase family protein

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MDWGPIIDGHSDFVLSLLETGRDFLVESHEGHVDLPRAQRGRLGAMLSAVFVRNEYLPAQALARTMRGVDRLRATVARSR
GAMEIVTDVDQLERCLDRGVFGAILHFEGAEAIDAEFAVLRLSYDLGLRSLGLTWSRPNIFAEGVGPENRGGGLTKLGRE
LVCACNEMGILIDVSHLNDAGFWDVLEESTRPVVASHSNCRALCAVERNLTDDQIRALAEKDGLVGINFHVGFIREGAER
PSDVTLDDVIAHIDHIVQLVGVDHVGFGSDFDGATMPAELADAAQLPRLVEALARHGYDEQALRKISRDNWLRVFRAVWR
S

Sequences:

>Translated_321_residues
MDWGPIIDGHSDFVLSLLETGRDFLVESHEGHVDLPRAQRGRLGAMLSAVFVRNEYLPAQALARTMRGVDRLRATVARSR
GAMEIVTDVDQLERCLDRGVFGAILHFEGAEAIDAEFAVLRLSYDLGLRSLGLTWSRPNIFAEGVGPENRGGGLTKLGRE
LVCACNEMGILIDVSHLNDAGFWDVLEESTRPVVASHSNCRALCAVERNLTDDQIRALAEKDGLVGINFHVGFIREGAER
PSDVTLDDVIAHIDHIVQLVGVDHVGFGSDFDGATMPAELADAAQLPRLVEALARHGYDEQALRKISRDNWLRVFRAVWR
S
>Mature_321_residues
MDWGPIIDGHSDFVLSLLETGRDFLVESHEGHVDLPRAQRGRLGAMLSAVFVRNEYLPAQALARTMRGVDRLRATVARSR
GAMEIVTDVDQLERCLDRGVFGAILHFEGAEAIDAEFAVLRLSYDLGLRSLGLTWSRPNIFAEGVGPENRGGGLTKLGRE
LVCACNEMGILIDVSHLNDAGFWDVLEESTRPVVASHSNCRALCAVERNLTDDQIRALAEKDGLVGINFHVGFIREGAER
PSDVTLDDVIAHIDHIVQLVGVDHVGFGSDFDGATMPAELADAAQLPRLVEALARHGYDEQALRKISRDNWLRVFRAVWR
S

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI189458885, Length=328, Percent_Identity=30.4878048780488, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI4758190, Length=328, Percent_Identity=30.4878048780488, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI11641269, Length=325, Percent_Identity=32.3076923076923, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI193211608, Length=326, Percent_Identity=29.4478527607362, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI193211610, Length=326, Percent_Identity=29.7546012269939, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI221475880, Length=340, Percent_Identity=30.2941176470588, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI281362638, Length=336, Percent_Identity=29.7619047619048, Blast_Score=154, Evalue=8e-38,
Organism=Drosophila melanogaster, GI281362636, Length=336, Percent_Identity=29.7619047619048, Blast_Score=154, Evalue=8e-38,
Organism=Drosophila melanogaster, GI161083233, Length=334, Percent_Identity=29.3413173652695, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI21356391, Length=304, Percent_Identity=26.6447368421053, Blast_Score=85, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 35357; Mature: 35357

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWGPIIDGHSDFVLSLLETGRDFLVESHEGHVDLPRAQRGRLGAMLSAVFVRNEYLPAQ
CCCCCCCCCCHHHHHHHHHCCHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHH
ALARTMRGVDRLRATVARSRGAMEIVTDVDQLERCLDRGVFGAILHFEGAEAIDAEFAVL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHEEHEEECCCCHHCHHHEEE
RLSYDLGLRSLGLTWSRPNIFAEGVGPENRGGGLTKLGRELVCACNEMGILIDVSHLNDA
EEEHHHCHHHCCCEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
GFWDVLEESTRPVVASHSNCRALCAVERNLTDDQIRALAEKDGLVGINFHVGFIREGAER
CHHHHHHHCCCCEEECCCCCCEEEEHHCCCCHHHHHHHHHCCCEEEEEEEEHHHHHCCCC
PSDVTLDDVIAHIDHIVQLVGVDHVGFGSDFDGATMPAELADAAQLPRLVEALARHGYDE
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
QALRKISRDNWLRVFRAVWRS
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDWGPIIDGHSDFVLSLLETGRDFLVESHEGHVDLPRAQRGRLGAMLSAVFVRNEYLPAQ
CCCCCCCCCCHHHHHHHHHCCHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHH
ALARTMRGVDRLRATVARSRGAMEIVTDVDQLERCLDRGVFGAILHFEGAEAIDAEFAVL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHEEHEEECCCCHHCHHHEEE
RLSYDLGLRSLGLTWSRPNIFAEGVGPENRGGGLTKLGRELVCACNEMGILIDVSHLNDA
EEEHHHCHHHCCCEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
GFWDVLEESTRPVVASHSNCRALCAVERNLTDDQIRALAEKDGLVGINFHVGFIREGAER
CHHHHHHHCCCCEEECCCCCCEEEEHHCCCCHHHHHHHHHCCCEEEEEEEEHHHHHCCCC
PSDVTLDDVIAHIDHIVQLVGVDHVGFGSDFDGATMPAELADAAQLPRLVEALARHGYDE
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
QALRKISRDNWLRVFRAVWRS
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]