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The map label for this gene is clpB [H]

Identifier: 221633020

GI number: 221633020

Start: 1001854

End: 1004307

Strand: Reverse

Name: clpB [H]

Synonym: trd_1035

Alternate gene names: 221633020

Gene position: 1004307-1001854 (Counterclockwise)

Preceding gene: 221633021

Following gene: 221633019

Centisome position: 50.14

GC content: 61.86

Gene sequence:

>2454_bases
ATGGCGGACAAGTTCGAGAAGTTCACGGAACGAGCCCGGAAAGTGCTCGCGCTGGCCCAAGAGGAAGCGCGACGCTTCAA
TCACAACTACATCGGCACCGAGCACCTGCTCCTCGGTCTCGTGCGCGAGGGGGAAGGTGTGGCGGCACGCGTGCTCCAGA
GCATGGGCGTGCAGCTGCCCAAGGTGCGTAGTGCCGTCGAGTTCATCATCGGGCGAGGGGAAAGCACGGTCGTCGGTGAG
ATCGGGCTGACCCCGCGCGCTCGCAAGGTGATCGAGTATGCCGTGGATGAAGCGCGCCGACTCGGGCACCACTACATCGG
AACGGAGCATCTGTTGCTCGGGCTCGTTCGCGAGGGTGAGGGTATCGCTGCGGGCGTGCTGGAGAGCCTCGGCGTGAACC
TGGAAAAGGTTCGCCAGCAGGTCCTACAGGTGCTCGCCCAAGGGACCGCCTACCAGCAGCGTGCGCAGCAGACCAAGACG
CCGTACCTCGATGCGCTCGGGTTCGACCTCACCGAGGCAGCTCGGCTCGGGAAGCTCGATCCAGTCATCGGTCGGCACAA
CGAAATCGAACGAGTGATGCAGATCCTCTCGCGCCGGACGAAGAACAACCCAGCCTTGATCGGTGAGCCAGGGGTCGGTA
AGACCGCGATCGTGGAGGGGCTGGCGCAGCGGATCGTTGCCGGTGACGTGCCGGAGCCACTGCAGGGCAAGCGCCTGGTC
GCCCTGGATATCGGTGCCTTGGTCGCTGGAACCAAGTATCGAGGCGAGTTCGAAGAGCGGCTGAAGAAGATCGTCGCGGA
GGTCAAGGAGTCTGGGACGATCCTGTTCATCGACGAACTCCACACGTTGGTCGGTGCCGGGGCGGCCGAGGGAGCAGTCG
ATGCGGCGAACATCTTGAAGCCCGCCTTGTCGCGCGGTGAGGTGCAAACGATCGGTGCCACGACGCTCGACGAGTATCGG
AAGTACATCGAGCGAGATGCAGCATTGGAGCGGCGATTCCAACCCGTCATCGTGAACGAGCCGACTGTCGAGGAAACGAT
CGAGATCCTGAAGGGGATCCGTGAGCGGTACGAGGAGCATCACAAGCTCAAGATTTCGGATGAGGCGCTTCACGCGGCCG
CTGTGTTGGCAGCACGTTACGTGACCGATCGGTTCTTGCCTGACAAGGCGATCGACCTGGTCGATGAGGCTGCATCGCGT
GTCCGGATGTACCGTTCTGCCTCACCACCGTCGCTCAAGGAGGCTCGTCGCGGGCTGGAGTCGCTGCGGCGCGAACTGGA
TGCCGCGGTGGCCAGCCAGGAGTTCGAGTTGGCTGCCGAGTTGCGCGAGCGCGAGCGACAGTTGGTGCATCGTATCCACG
AGCTGGAGCAGCATTGGCGCGAAGAACAAGGCCAGGAAGAGCCGATCGTCACGGAAGAGGATATTGCCCAGGTCGTCTCG
ATGTGGACGGGTATTCCGCTCACCCGTTTGCACACCGAGGAAAGCGAGCGCCTACTCCATATGGAGGAAGCGCTGCATGA
GCGTGTGATCGGGCAGGACGAAGCGATTTCGACGCTCGCTCGTGCTGTGCGCCGTGCTCGTGCGGGACTCAAGGACCCGC
GTCGACCGATCGGGACCTTCATCTTCCTCGGACCGACGGGAGTGGGGAAGACGCTGTTGGCGCGTGCGCTCGCTGAGTTC
ATGTTCGGTAGTGAGGATGCGCTGATCAAGATCGACATGAGCGAATTCATGGAGCGGCACACGGTGTCGCGTCTGGTGGG
GGCGCCGCCCGGCTACATCGGGTACGAGGAAGGTGGACAGCTGACGGAAGCCGTGCGCCGCAAGCCGTACTCGGTGATCC
TGCTCGACGAGATCGAGAAAGCGCATCCGGAAGCGTTCAACATCCTCCTCCAGATCATGGAGGATGGGAACCTGACGGAT
GCGAAAGGCCGGCGTGTCGACTTCCGGAACACCATCTTGATCATGACGTCGAACATCGGGGCGGAACTGATCCAGCGCGA
AGGTAGCCTCGGCTTTGCAGTGGCTGACGATCCGACCAAGAAGATGCAAGCTGATTACACTGCGATGAAGGACAAAGTCC
TCTCGCAGCTCAAGCAGACCTTCCGGCCGGAGTTCCTGAACCGAATCGATGCGGTCATCGTCTTCCATCCGCTGACGCCA
GAACACGTCCGACAGATCGTCGATCTGGAACTCAAGCGGATCCGCAAGCAGCTGGCGGAGCAACAGATCGGTCTCGAAGT
CACCGATGCGGCGAAGGATCTTTTGGCGAAGCGCGGCTACGACCGGCAGTTCGGAGCCCGTCCATTGCGGCGGATCATCC
AGAACTTGATCGAGGATCCGTTGGCGGAAGCGATCCTCGCTGGTCGGTTCAAGCCGGGGAGCACGGTCGTCATCAATGTC
CGCGACGACTTGCTCACCATCGAACCGGCAGAGGCACTGAGCACAGTCTCTTAA

Upstream 100 bases:

>100_bases
GGTGAGACGCAGGAATCGACGAGCCGCGGAGCTTTCGCGCACCGGCTTTCTTGCCGACATCCCATGAGAGAGTACGGGCA
TTCGCCCGGGAGTGTGTGCT

Downstream 100 bases:

>100_bases
CGGAGACGGTTTTCTCAGCGAGACACGGCACTGGTTCCGGCCAGTGCCGTGTTCGTTTATACTTCCCACTCGAACGGGTG
TTCTTGGTGCGAGAGGAGGA

Product: ClpC ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 817; Mature: 816

Protein sequence:

>817_residues
MADKFEKFTERARKVLALAQEEARRFNHNYIGTEHLLLGLVREGEGVAARVLQSMGVQLPKVRSAVEFIIGRGESTVVGE
IGLTPRARKVIEYAVDEARRLGHHYIGTEHLLLGLVREGEGIAAGVLESLGVNLEKVRQQVLQVLAQGTAYQQRAQQTKT
PYLDALGFDLTEAARLGKLDPVIGRHNEIERVMQILSRRTKNNPALIGEPGVGKTAIVEGLAQRIVAGDVPEPLQGKRLV
ALDIGALVAGTKYRGEFEERLKKIVAEVKESGTILFIDELHTLVGAGAAEGAVDAANILKPALSRGEVQTIGATTLDEYR
KYIERDAALERRFQPVIVNEPTVEETIEILKGIRERYEEHHKLKISDEALHAAAVLAARYVTDRFLPDKAIDLVDEAASR
VRMYRSASPPSLKEARRGLESLRRELDAAVASQEFELAAELRERERQLVHRIHELEQHWREEQGQEEPIVTEEDIAQVVS
MWTGIPLTRLHTEESERLLHMEEALHERVIGQDEAISTLARAVRRARAGLKDPRRPIGTFIFLGPTGVGKTLLARALAEF
MFGSEDALIKIDMSEFMERHTVSRLVGAPPGYIGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEAFNILLQIMEDGNLTD
AKGRRVDFRNTILIMTSNIGAELIQREGSLGFAVADDPTKKMQADYTAMKDKVLSQLKQTFRPEFLNRIDAVIVFHPLTP
EHVRQIVDLELKRIRKQLAEQQIGLEVTDAAKDLLAKRGYDRQFGARPLRRIIQNLIEDPLAEAILAGRFKPGSTVVINV
RDDLLTIEPAEALSTVS

Sequences:

>Translated_817_residues
MADKFEKFTERARKVLALAQEEARRFNHNYIGTEHLLLGLVREGEGVAARVLQSMGVQLPKVRSAVEFIIGRGESTVVGE
IGLTPRARKVIEYAVDEARRLGHHYIGTEHLLLGLVREGEGIAAGVLESLGVNLEKVRQQVLQVLAQGTAYQQRAQQTKT
PYLDALGFDLTEAARLGKLDPVIGRHNEIERVMQILSRRTKNNPALIGEPGVGKTAIVEGLAQRIVAGDVPEPLQGKRLV
ALDIGALVAGTKYRGEFEERLKKIVAEVKESGTILFIDELHTLVGAGAAEGAVDAANILKPALSRGEVQTIGATTLDEYR
KYIERDAALERRFQPVIVNEPTVEETIEILKGIRERYEEHHKLKISDEALHAAAVLAARYVTDRFLPDKAIDLVDEAASR
VRMYRSASPPSLKEARRGLESLRRELDAAVASQEFELAAELRERERQLVHRIHELEQHWREEQGQEEPIVTEEDIAQVVS
MWTGIPLTRLHTEESERLLHMEEALHERVIGQDEAISTLARAVRRARAGLKDPRRPIGTFIFLGPTGVGKTLLARALAEF
MFGSEDALIKIDMSEFMERHTVSRLVGAPPGYIGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEAFNILLQIMEDGNLTD
AKGRRVDFRNTILIMTSNIGAELIQREGSLGFAVADDPTKKMQADYTAMKDKVLSQLKQTFRPEFLNRIDAVIVFHPLTP
EHVRQIVDLELKRIRKQLAEQQIGLEVTDAAKDLLAKRGYDRQFGARPLRRIIQNLIEDPLAEAILAGRFKPGSTVVINV
RDDLLTIEPAEALSTVS
>Mature_816_residues
ADKFEKFTERARKVLALAQEEARRFNHNYIGTEHLLLGLVREGEGVAARVLQSMGVQLPKVRSAVEFIIGRGESTVVGEI
GLTPRARKVIEYAVDEARRLGHHYIGTEHLLLGLVREGEGIAAGVLESLGVNLEKVRQQVLQVLAQGTAYQQRAQQTKTP
YLDALGFDLTEAARLGKLDPVIGRHNEIERVMQILSRRTKNNPALIGEPGVGKTAIVEGLAQRIVAGDVPEPLQGKRLVA
LDIGALVAGTKYRGEFEERLKKIVAEVKESGTILFIDELHTLVGAGAAEGAVDAANILKPALSRGEVQTIGATTLDEYRK
YIERDAALERRFQPVIVNEPTVEETIEILKGIRERYEEHHKLKISDEALHAAAVLAARYVTDRFLPDKAIDLVDEAASRV
RMYRSASPPSLKEARRGLESLRRELDAAVASQEFELAAELRERERQLVHRIHELEQHWREEQGQEEPIVTEEDIAQVVSM
WTGIPLTRLHTEESERLLHMEEALHERVIGQDEAISTLARAVRRARAGLKDPRRPIGTFIFLGPTGVGKTLLARALAEFM
FGSEDALIKIDMSEFMERHTVSRLVGAPPGYIGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEAFNILLQIMEDGNLTDA
KGRRVDFRNTILIMTSNIGAELIQREGSLGFAVADDPTKKMQADYTAMKDKVLSQLKQTFRPEFLNRIDAVIVFHPLTPE
HVRQIVDLELKRIRKQLAEQQIGLEVTDAAKDLLAKRGYDRQFGARPLRRIIQNLIEDPLAEAILAGRFKPGSTVVINVR
DDLLTIEPAEALSTVS

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=322, Percent_Identity=35.0931677018634, Blast_Score=197, Evalue=4e-50,
Organism=Escherichia coli, GI1788943, Length=870, Percent_Identity=46.551724137931, Blast_Score=746, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=408, Percent_Identity=39.7058823529412, Blast_Score=289, Evalue=5e-79,
Organism=Saccharomyces cerevisiae, GI6320464, Length=727, Percent_Identity=44.5667125171939, Blast_Score=571, Evalue=1e-163,
Organism=Saccharomyces cerevisiae, GI6323002, Length=877, Percent_Identity=38.8825541619156, Blast_Score=569, Evalue=1e-163,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 91176; Mature: 91045

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKFEKFTERARKVLALAQEEARRFNHNYIGTEHLLLGLVREGEGVAARVLQSMGVQLP
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCH
KVRSAVEFIIGRGESTVVGEIGLTPRARKVIEYAVDEARRLGHHYIGTEHLLLGLVREGE
HHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
GIAAGVLESLGVNLEKVRQQVLQVLAQGTAYQQRAQQTKTPYLDALGFDLTEAARLGKLD
CHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHCCCHHHHHHCCCCC
PVIGRHNEIERVMQILSRRTKNNPALIGEPGVGKTAIVEGLAQRIVAGDVPEPLQGKRLV
CCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEE
ALDIGALVAGTKYRGEFEERLKKIVAEVKESGTILFIDELHTLVGAGAAEGAVDAANILK
EEEHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCCCCHHHHHHHH
PALSRGEVQTIGATTLDEYRKYIERDAALERRFQPVIVNEPTVEETIEILKGIRERYEEH
HHHCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHH
HKLKISDEALHAAAVLAARYVTDRFLPDKAIDLVDEAASRVRMYRSASPPSLKEARRGLE
CCEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SLRRELDAAVASQEFELAAELRERERQLVHRIHELEQHWREEQGQEEPIVTEEDIAQVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
MWTGIPLTRLHTEESERLLHMEEALHERVIGQDEAISTLARAVRRARAGLKDPRRPIGTF
HHCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCE
IFLGPTGVGKTLLARALAEFMFGSEDALIKIDMSEFMERHTVSRLVGAPPGYIGYEEGGQ
EEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCH
LTEAVRRKPYSVILLDEIEKAHPEAFNILLQIMEDGNLTDAKGRRVDFRNTILIMTSNIG
HHHHHHCCCCEEEEEHHHHHHCHHHHHHHHHHHHCCCCCCCCCCEEECCCEEEEEECCHH
AELIQREGSLGFAVADDPTKKMQADYTAMKDKVLSQLKQTFRPEFLNRIDAVIVFHPLTP
HHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCEEEEEECCCH
EHVRQIVDLELKRIRKQLAEQQIGLEVTDAAKDLLAKRGYDRQFGARPLRRIIQNLIEDP
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
LAEAILAGRFKPGSTVVINVRDDLLTIEPAEALSTVS
HHHHHHHCCCCCCCEEEEEECCCEEEECCHHHHHCCC
>Mature Secondary Structure 
ADKFEKFTERARKVLALAQEEARRFNHNYIGTEHLLLGLVREGEGVAARVLQSMGVQLP
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCH
KVRSAVEFIIGRGESTVVGEIGLTPRARKVIEYAVDEARRLGHHYIGTEHLLLGLVREGE
HHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
GIAAGVLESLGVNLEKVRQQVLQVLAQGTAYQQRAQQTKTPYLDALGFDLTEAARLGKLD
CHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHCCCHHHHHHCCCCC
PVIGRHNEIERVMQILSRRTKNNPALIGEPGVGKTAIVEGLAQRIVAGDVPEPLQGKRLV
CCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEE
ALDIGALVAGTKYRGEFEERLKKIVAEVKESGTILFIDELHTLVGAGAAEGAVDAANILK
EEEHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCCCCHHHHHHHH
PALSRGEVQTIGATTLDEYRKYIERDAALERRFQPVIVNEPTVEETIEILKGIRERYEEH
HHHCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHH
HKLKISDEALHAAAVLAARYVTDRFLPDKAIDLVDEAASRVRMYRSASPPSLKEARRGLE
CCEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SLRRELDAAVASQEFELAAELRERERQLVHRIHELEQHWREEQGQEEPIVTEEDIAQVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
MWTGIPLTRLHTEESERLLHMEEALHERVIGQDEAISTLARAVRRARAGLKDPRRPIGTF
HHCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCE
IFLGPTGVGKTLLARALAEFMFGSEDALIKIDMSEFMERHTVSRLVGAPPGYIGYEEGGQ
EEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCH
LTEAVRRKPYSVILLDEIEKAHPEAFNILLQIMEDGNLTDAKGRRVDFRNTILIMTSNIG
HHHHHHCCCCEEEEEHHHHHHCHHHHHHHHHHHHCCCCCCCCCCEEECCCEEEEEECCHH
AELIQREGSLGFAVADDPTKKMQADYTAMKDKVLSQLKQTFRPEFLNRIDAVIVFHPLTP
HHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCEEEEEECCCH
EHVRQIVDLELKRIRKQLAEQQIGLEVTDAAKDLLAKRGYDRQFGARPLRRIIQNLIEDP
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
LAEAILAGRFKPGSTVVINVRDDLLTIEPAEALSTVS
HHHHHHHCCCCCCCEEEEEECCCEEEECCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]