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The map label for this gene is ctaC [H]

Identifier: 221632721

GI number: 221632721

Start: 701829

End: 702995

Strand: Reverse

Name: ctaC [H]

Synonym: trd_0709

Alternate gene names: 221632721

Gene position: 702995-701829 (Counterclockwise)

Preceding gene: 221632722

Following gene: 221632720

Centisome position: 35.1

GC content: 60.15

Gene sequence:

>1167_bases
ATGGTCGTGGAGAGTCGCCTGGAAAGGCGGCGCATCGGAGCGAGGTGCTGCGGGGAAGGGGCAAAACGCGTGAAGCGAAT
TGCTAAACGACCCAGTACTCGGTCGGTTCTCGTCATGCTGCTGTTGGCGCTCACGGTAGTGCTCACCAGCGGCTGTGGTG
TCATCGGCGGCAAGATCGCCTCGACATCGGATCCAGCTGGTGACCAAGCACGCCTGATCTGGGATCTCTTCATCACGCCC
GTCTGGTGGTTGGTCATCTTCGTCTTCGTCCTCGTCACGGGCTGGATTCTCATCAACATCGTCCGTTTCCGACGTCAGCC
TGGCGACACGCGTATTCCACCGCAAGTACACGGCAATCAACGCCTCGAGATCGCCTGGACACTCATCCCGGCGATCATTC
TGGCCCTGATCGCTGTGCCCTCTACCCGGCTGATCTTCGAACTAAATCGTGACCCTGGTCCTGGCAGCAACGCGCTCCGT
GCCCAGGTGATCGGCCACCAATGGTGGTGGGAGTTCCGCTACCCCGAGTACGGCATCGTGACCGCCGGTGACCTCCATCT
CGTTGTCGGTCGTCCCGTCGTTCTCACAATCACCTCTCACGATGTGATCCATTCCTTCTGGCCGCCGCGCCTGGCGGGCA
AGGTGGACGCCGTGCCTGGCCGAGCGCACACGATGGTCTTCACGCCCGAAGAGACTGGTGTTTTTTATGGCCAGTGTGCC
GAGTTGTGCGGCGCGCAACATGCGCACATGCAGTTCCGCGTCGTCGTCCAAACTCAGGAAGAGTTCGATGCCTGGGTCGC
AAAGCTCCGCCGCCCCATCCCCGAGCCGCCGGCCGGCAGCCTGGCTGCAACAGGCCAGCAGTTGTTTGCAGGGAAGGCGG
GATGCGCCGGATGTCACCAGGTTTCGCCAACCTATGATCCTGTGACGCCGATAAACAAAACACTGGCCGTTGGACCGAAT
CTCGCGTATATCGGTGAACGTCATGTCCTGGCGGCCTTCACCGACAATACGCCGGAGGAGCTGCATCGCTGGATTGCGTC
TACCTGCGATGTCAAGCCCTACTCCATCATGTGCGAGAAGTGGTGGCGGATCCGAGCCGAGCAGAACACATTGTTGACGA
CAGAAGAGGTTGATGCCATAGTGGCATACATGCTGTCACTTCAGTGA

Upstream 100 bases:

>100_bases
GTGCGCTTGCCACCGCGGTTCCACATCGCATACTCGTTGCAACACGACATACTGCGCATGAAGAACCCGAATCGTGACAG
CAATCACGATCCAGGGTAGA

Downstream 100 bases:

>100_bases
ACCCGCAGGACTTCATACGGTAGGGGGTAGGCGGCATGGACAGCAGGGATAGAATGTCGAGAGAAAGCAATTGGGGCTCC
GGAGAGACGACGCTCCGAGC

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MVVESRLERRRIGARCCGEGAKRVKRIAKRPSTRSVLVMLLLALTVVLTSGCGVIGGKIASTSDPAGDQARLIWDLFITP
VWWLVIFVFVLVTGWILINIVRFRRQPGDTRIPPQVHGNQRLEIAWTLIPAIILALIAVPSTRLIFELNRDPGPGSNALR
AQVIGHQWWWEFRYPEYGIVTAGDLHLVVGRPVVLTITSHDVIHSFWPPRLAGKVDAVPGRAHTMVFTPEETGVFYGQCA
ELCGAQHAHMQFRVVVQTQEEFDAWVAKLRRPIPEPPAGSLAATGQQLFAGKAGCAGCHQVSPTYDPVTPINKTLAVGPN
LAYIGERHVLAAFTDNTPEELHRWIASTCDVKPYSIMCEKWWRIRAEQNTLLTTEEVDAIVAYMLSLQ

Sequences:

>Translated_388_residues
MVVESRLERRRIGARCCGEGAKRVKRIAKRPSTRSVLVMLLLALTVVLTSGCGVIGGKIASTSDPAGDQARLIWDLFITP
VWWLVIFVFVLVTGWILINIVRFRRQPGDTRIPPQVHGNQRLEIAWTLIPAIILALIAVPSTRLIFELNRDPGPGSNALR
AQVIGHQWWWEFRYPEYGIVTAGDLHLVVGRPVVLTITSHDVIHSFWPPRLAGKVDAVPGRAHTMVFTPEETGVFYGQCA
ELCGAQHAHMQFRVVVQTQEEFDAWVAKLRRPIPEPPAGSLAATGQQLFAGKAGCAGCHQVSPTYDPVTPINKTLAVGPN
LAYIGERHVLAAFTDNTPEELHRWIASTCDVKPYSIMCEKWWRIRAEQNTLLTTEEVDAIVAYMLSLQ
>Mature_388_residues
MVVESRLERRRIGARCCGEGAKRVKRIAKRPSTRSVLVMLLLALTVVLTSGCGVIGGKIASTSDPAGDQARLIWDLFITP
VWWLVIFVFVLVTGWILINIVRFRRQPGDTRIPPQVHGNQRLEIAWTLIPAIILALIAVPSTRLIFELNRDPGPGSNALR
AQVIGHQWWWEFRYPEYGIVTAGDLHLVVGRPVVLTITSHDVIHSFWPPRLAGKVDAVPGRAHTMVFTPEETGVFYGQCA
ELCGAQHAHMQFRVVVQTQEEFDAWVAKLRRPIPEPPAGSLAATGQQLFAGKAGCAGCHQVSPTYDPVTPINKTLAVGPN
LAYIGERHVLAAFTDNTPEELHRWIASTCDVKPYSIMCEKWWRIRAEQNTLLTTEEVDAIVAYMLSLQ

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=156, Percent_Identity=38.4615384615385, Blast_Score=116, Evalue=3e-26,
Organism=Escherichia coli, GI1786635, Length=249, Percent_Identity=26.5060240963855, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6226540, Length=214, Percent_Identity=28.9719626168224, Blast_Score=101, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM; PF00034 Cytochrom_C [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 43141; Mature: 43141

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVESRLERRRIGARCCGEGAKRVKRIAKRPSTRSVLVMLLLALTVVLTSGCGVIGGKIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
STSDPAGDQARLIWDLFITPVWWLVIFVFVLVTGWILINIVRFRRQPGDTRIPPQVHGNQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
RLEIAWTLIPAIILALIAVPSTRLIFELNRDPGPGSNALRAQVIGHQWWWEFRYPEYGIV
EEEEHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCEEEEEEECCCCCEE
TAGDLHLVVGRPVVLTITSHDVIHSFWPPRLAGKVDAVPGRAHTMVFTPEETGVFYGQCA
ECCCEEEEECCCEEEEEECHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHH
ELCGAQHAHMQFRVVVQTQEEFDAWVAKLRRPIPEPPAGSLAATGQQLFAGKAGCAGCHQ
HHCCCCCCCEEEEEEEECHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHCCCCCCCCCCC
VSPTYDPVTPINKTLAVGPNLAYIGERHVLAAFTDNTPEELHRWIASTCDVKPYSIMCEK
CCCCCCCCCCCCCEEEECCCEEEECCCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHH
WWRIRAEQNTLLTTEEVDAIVAYMLSLQ
HHHHCCCCCCEECHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVVESRLERRRIGARCCGEGAKRVKRIAKRPSTRSVLVMLLLALTVVLTSGCGVIGGKIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
STSDPAGDQARLIWDLFITPVWWLVIFVFVLVTGWILINIVRFRRQPGDTRIPPQVHGNQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
RLEIAWTLIPAIILALIAVPSTRLIFELNRDPGPGSNALRAQVIGHQWWWEFRYPEYGIV
EEEEHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCEEEEEEECCCCCEE
TAGDLHLVVGRPVVLTITSHDVIHSFWPPRLAGKVDAVPGRAHTMVFTPEETGVFYGQCA
ECCCEEEEECCCEEEEEECHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHH
ELCGAQHAHMQFRVVVQTQEEFDAWVAKLRRPIPEPPAGSLAATGQQLFAGKAGCAGCHQ
HHCCCCCCCEEEEEEEECHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHCCCCCCCCCCC
VSPTYDPVTPINKTLAVGPNLAYIGERHVLAAFTDNTPEELHRWIASTCDVKPYSIMCEK
CCCCCCCCCCCCCEEEECCCEEEECCCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHH
WWRIRAEQNTLLTTEEVDAIVAYMLSLQ
HHHHCCCCCCEECHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7678007 [H]