Click here to switch to the map view.

The map label for this gene is ctaD [H]

Identifier: 221632720

GI number: 221632720

Start: 699774

End: 701693

Strand: Reverse

Name: ctaD [H]

Synonym: trd_0708

Alternate gene names: 221632720

Gene position: 701693-699774 (Counterclockwise)

Preceding gene: 221632721

Following gene: 221632719

Centisome position: 35.03

GC content: 58.96

Gene sequence:

>1920_bases
ATGGCTGAAGCGGCGATCAGACTCGAACAGGCAGGATACCGGCGCTCCGCGCTGGTCGAGTGGTTGACCACCGTCGACCA
CAAGAAAATCGGCATTCTGTACTACTGGACATCGATCATCTACCTTCTTCTCGCTGGCTTTCTGGCTCTCCTGATGCGTA
TCCAGCTAGCCCAACCGAACATGAACTTTCTTGGGCCGAAAACCTACAATGAAGTCATGACCATGCACGGGACGATGATG
ATTTTCGCGGTCGCCATGCCGTTGAACGCGGCGTTCTTCAATATCGCCGTGCCACTCATGATCGGTGCTCGTGATGTGGC
CTTCCCCCGTTTGAACGCGTTCTCCTATTGGTCCTTCCTTTTCGGCTCGCTCCTCCTCTGGTCCAGCTTCCTTTTCGGAC
ACGTGCCGGATGCTGGGTGGACCGGTTACGCAAATCTTTCGAGCAGCCGACTGTACTCGGCCGGACCCGGACTCGACTTC
TGGAACCTCAGTCTCCAGGTGCTCGGTATCAGCTCGATCGCTGGTGCGCTCAACTTCTTCGTCACCATCGTCAACATGCG
GGCCCCTGGTATGTCGCTCATGCGCATGCCGGTCTACGTCTGGATGGTTCTCATCACAGCGATTCTGATTCTTCTTGCCT
TCCCGTCGCTGACCGTCGGCCTCTTCATGATCATGTTCGACCGCTACTTCAGTACCAATTTCTTCAACCCCGTCCACGGT
GGTGATCCCGTCATTTGGCAGCACTTGTTCTGGATTTTCGGTCATCCCGAGGTGTACATCCTGGTTCTGCCGCCGATGGG
CATCATCTCCGAGATTTTGCCGACGTTCTCCCGTAAGCCGCTCTTCGGTGCACCCTTCGTGATCTTCGCTGGTATGGCGA
TCGCGTTCTTGAGTTTCTTCGTCTGGGCCCATCATATGTTCACCGTCGGCCTCGGCCCGGTACCCAACGCGCTCTTCGCC
GCCTCGACTATGCTGATCGGGATCCCGACCGGGGTGAAGGTGTTCAACTGGCTCGCCACCATGTGGGGCGGCTCGATCGA
TTTCAAGACACCGATGAAGTTCGCGACCGCCGCCGTTTGGCTCCTCATGGTCGGTGGGGTCACCGGCGTGATGCACGCGA
CCGTCCCCCTCGACTACCAGCAGCATGACTCCTACTTCATCGTTGCTCACTTCCACTACATCATCTTCGGCGTGATCGTG
AACGCCCTGTTGGCTGGAACGTACTACTGGTTCCCCAAGATGTACGGGCGCTTGCTCGATGAGCGGCTCGGCACGCTGCA
CTTCTGGTTGACCTTCATCGGCATGAATCTGACGTTCTTCCCCATGCACTTCGTCGGCCTGGATGGTATGCCGCGCCGGT
ACTTCACCTATTCGGCCGAGACCGGTTGGGGTACCTGGAACCTAGTAGTCACTATCGGTGCCTTCATCCTCGGACTCGCC
CAGGTCGTGCTGCTCGTCAACGTCTACAAGACGATGCGTCAACCCGCGACGGCCCCGGCCGACCCGTGGGATGGTCGCAC
GCTCGAGTGGACCATTCCCTCGCCACCCCCGGCGTACAACTTCGCGGTCATTCCCACCGTCCGAGGACGTGATGCCTACT
GGATCGAAAAGTATGGCGACGGACATCACACGCCAGTCGTGAGCGATGTGACGCAACGACGTGAGACTCGGCTCGAACAA
CGTGACAATCCGGGTCACGGGCTCCCCGCTGGCGTGCATCTGCCCAAGCCGTCATGGTGGCCGATGATCGTGTCGGCTGG
ACTGACCGCGATGGCCGCTGGCATGATCATGCACGGCACGGAGACACTAGGGCCGCTTGGATTCCCGATCGTCGGACTCG
GCACGCTCATCGTCTTCTTCGGTCTGCTCGGCTGGCACTTCGAGCCAGCGATCGAACACGAGGAGGCACACGTCTCGTGA

Upstream 100 bases:

>100_bases
ATGGACAGCAGGGATAGAATGTCGAGAGAAAGCAATTGGGGCTCCGGAGAGACGACGCTCCGAGCACGTTCGGACCAGCA
CCAAGCGTGGGAGGGCACCG

Downstream 100 bases:

>100_bases
GGAGGGCGTCCTGGGGCGGGTTTTCACCCGCCCCAGAGACTCGGTTCGTGCAGGTCGTTGGAGAGAAGGGATCGCGAGGT
GGGTCACTCGGTCACGGCGC

Product: quinol oxidase polypeptide I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 639; Mature: 638

Protein sequence:

>639_residues
MAEAAIRLEQAGYRRSALVEWLTTVDHKKIGILYYWTSIIYLLLAGFLALLMRIQLAQPNMNFLGPKTYNEVMTMHGTMM
IFAVAMPLNAAFFNIAVPLMIGARDVAFPRLNAFSYWSFLFGSLLLWSSFLFGHVPDAGWTGYANLSSSRLYSAGPGLDF
WNLSLQVLGISSIAGALNFFVTIVNMRAPGMSLMRMPVYVWMVLITAILILLAFPSLTVGLFMIMFDRYFSTNFFNPVHG
GDPVIWQHLFWIFGHPEVYILVLPPMGIISEILPTFSRKPLFGAPFVIFAGMAIAFLSFFVWAHHMFTVGLGPVPNALFA
ASTMLIGIPTGVKVFNWLATMWGGSIDFKTPMKFATAAVWLLMVGGVTGVMHATVPLDYQQHDSYFIVAHFHYIIFGVIV
NALLAGTYYWFPKMYGRLLDERLGTLHFWLTFIGMNLTFFPMHFVGLDGMPRRYFTYSAETGWGTWNLVVTIGAFILGLA
QVVLLVNVYKTMRQPATAPADPWDGRTLEWTIPSPPPAYNFAVIPTVRGRDAYWIEKYGDGHHTPVVSDVTQRRETRLEQ
RDNPGHGLPAGVHLPKPSWWPMIVSAGLTAMAAGMIMHGTETLGPLGFPIVGLGTLIVFFGLLGWHFEPAIEHEEAHVS

Sequences:

>Translated_639_residues
MAEAAIRLEQAGYRRSALVEWLTTVDHKKIGILYYWTSIIYLLLAGFLALLMRIQLAQPNMNFLGPKTYNEVMTMHGTMM
IFAVAMPLNAAFFNIAVPLMIGARDVAFPRLNAFSYWSFLFGSLLLWSSFLFGHVPDAGWTGYANLSSSRLYSAGPGLDF
WNLSLQVLGISSIAGALNFFVTIVNMRAPGMSLMRMPVYVWMVLITAILILLAFPSLTVGLFMIMFDRYFSTNFFNPVHG
GDPVIWQHLFWIFGHPEVYILVLPPMGIISEILPTFSRKPLFGAPFVIFAGMAIAFLSFFVWAHHMFTVGLGPVPNALFA
ASTMLIGIPTGVKVFNWLATMWGGSIDFKTPMKFATAAVWLLMVGGVTGVMHATVPLDYQQHDSYFIVAHFHYIIFGVIV
NALLAGTYYWFPKMYGRLLDERLGTLHFWLTFIGMNLTFFPMHFVGLDGMPRRYFTYSAETGWGTWNLVVTIGAFILGLA
QVVLLVNVYKTMRQPATAPADPWDGRTLEWTIPSPPPAYNFAVIPTVRGRDAYWIEKYGDGHHTPVVSDVTQRRETRLEQ
RDNPGHGLPAGVHLPKPSWWPMIVSAGLTAMAAGMIMHGTETLGPLGFPIVGLGTLIVFFGLLGWHFEPAIEHEEAHVS
>Mature_638_residues
AEAAIRLEQAGYRRSALVEWLTTVDHKKIGILYYWTSIIYLLLAGFLALLMRIQLAQPNMNFLGPKTYNEVMTMHGTMMI
FAVAMPLNAAFFNIAVPLMIGARDVAFPRLNAFSYWSFLFGSLLLWSSFLFGHVPDAGWTGYANLSSSRLYSAGPGLDFW
NLSLQVLGISSIAGALNFFVTIVNMRAPGMSLMRMPVYVWMVLITAILILLAFPSLTVGLFMIMFDRYFSTNFFNPVHGG
DPVIWQHLFWIFGHPEVYILVLPPMGIISEILPTFSRKPLFGAPFVIFAGMAIAFLSFFVWAHHMFTVGLGPVPNALFAA
STMLIGIPTGVKVFNWLATMWGGSIDFKTPMKFATAAVWLLMVGGVTGVMHATVPLDYQQHDSYFIVAHFHYIIFGVIVN
ALLAGTYYWFPKMYGRLLDERLGTLHFWLTFIGMNLTFFPMHFVGLDGMPRRYFTYSAETGWGTWNLVVTIGAFILGLAQ
VVLLVNVYKTMRQPATAPADPWDGRTLEWTIPSPPPAYNFAVIPTVRGRDAYWIEKYGDGHHTPVVSDVTQRRETRLEQR
DNPGHGLPAGVHLPKPSWWPMIVSAGLTAMAAGMIMHGTETLGPLGFPIVGLGTLIVFFGLLGWHFEPAIEHEEAHVS

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=505, Percent_Identity=43.3663366336634, Blast_Score=365, Evalue=1e-101,
Organism=Escherichia coli, GI1786634, Length=585, Percent_Identity=41.7094017094017, Blast_Score=429, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6226519, Length=476, Percent_Identity=43.0672268907563, Blast_Score=384, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6226524, Length=322, Percent_Identity=42.8571428571429, Blast_Score=258, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6226523, Length=246, Percent_Identity=39.0243902439024, Blast_Score=156, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 71398; Mature: 71267

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEAAIRLEQAGYRRSALVEWLTTVDHKKIGILYYWTSIIYLLLAGFLALLMRIQLAQPN
CCCHHHHHHHCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MNFLGPKTYNEVMTMHGTMMIFAVAMPLNAAFFNIAVPLMIGARDVAFPRLNAFSYWSFL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
FGSLLLWSSFLFGHVPDAGWTGYANLSSSRLYSAGPGLDFWNLSLQVLGISSIAGALNFF
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCEEECEEEEEEHHHHHHHHHHH
VTIVNMRAPGMSLMRMPVYVWMVLITAILILLAFPSLTVGLFMIMFDRYFSTNFFNPVHG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GDPVIWQHLFWIFGHPEVYILVLPPMGIISEILPTFSRKPLFGAPFVIFAGMAIAFLSFF
CCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
VWAHHMFTVGLGPVPNALFAASTMLIGIPTGVKVFNWLATMWGGSIDFKTPMKFATAAVW
HHHHHHHHCCCCCCCHHHHHHHHHEEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LLMVGGVTGVMHATVPLDYQQHDSYFIVAHFHYIIFGVIVNALLAGTYYWFPKMYGRLLD
HHHHHCHHHHEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERLGTLHFWLTFIGMNLTFFPMHFVGLDGMPRRYFTYSAETGWGTWNLVVTIGAFILGLA
HHHHHHHHHHHHHHCCHHEEHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
QVVLLVNVYKTMRQPATAPADPWDGRTLEWTIPSPPPAYNFAVIPTVRGRDAYWIEKYGD
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCEEEEECCC
GHHTPVVSDVTQRRETRLEQRDNPGHGLPAGVHLPKPSWWPMIVSAGLTAMAAGMIMHGT
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
ETLGPLGFPIVGLGTLIVFFGLLGWHFEPAIEHEEAHVS
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AEAAIRLEQAGYRRSALVEWLTTVDHKKIGILYYWTSIIYLLLAGFLALLMRIQLAQPN
CCHHHHHHHCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCC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CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1964459; 2844737; 1652469 [H]