BacMap

Definition	Thermomicrobium roseum DSM 5159 chromosome, complete genome.
Accession	NC_011959
Length	2,003,006

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The map label for this gene is dnaJ [H]

Identifier: 221632680

GI number: 221632680

Start: 658260

End: 659285

Strand: Reverse

Name: dnaJ [H]

Synonym: trd_0663

Alternate gene names: 221632680

Gene position: 659285-658260 (Counterclockwise)

Preceding gene: 221632681

Following gene: 221632679

Centisome position: 32.91

GC content: 61.6

Gene sequence:

>1026_bases
ATGGAGTTCAAGGACTACTACAAGATTCTCGGCGTGCCGCGCGATGCGGATCAGGAGACGATCCGCAAGGCCTACTTGCG
TCTCGCGCGCAAGTACCACCCTGACGTCAACAAATCACCGGACGCCGAGGAGAAGTTCAAGGAAATCAACGAAGCGTACG
AGGTTCTTCGGGATCCGGAAAAGCGTGCTCGCTATGATCGCTTCGGAGCCGACTGGGAGCGCTATCAGCAAGCCGCTGGA
GCACAAGGAACCACGACCGACTTTGAGGAATGGTTCTTCGGCACTCGCGATCGAGCGCAGCGCGAGCGTCGTCGAACGAG
TGATTTCTCCGACTTCTTCGACCTTTTGTTCGGTGATCTCGGCGATTTCTTCGTGACGACTGGTGAGCGCATCCGGACAC
GCGCCCGGCCGGAGCGGGGACAGGATTACGAGCATCCGATCGAAGTCACGCTCCGCGAGGCCTATCGCGGCGCAACCCGC
CGCATCGATGTGAAGATCGACGAGCGTTGCCCGGCCTGCAATGGCACAGGACTGAACGGACGCGGCATCTGCCGTGTCTG
TGGCGGTAGCGGCTACGTGACTCGTACCAAGACGCTCGAAGTCAAGATCCCTGCTGGGGTACGCGATGGCTCGCGCATCC
GCATCGCCGGCCAGGGTGGACCGGGTGTAAACGGCGGACCACCGGGTGACCTCTATCTCCGGGTCCACCTGTTGCCGGAC
CCGCAGTTCGCACTCGAGGGCGACAATTTGCGAACCGAGGTGGAGGTGCCGCTCTACACGGCGATTCTCGGCGGAGAGGT
CACTGTTCCGACGCTCGACCGACCAGTCGTTCTACGCATTCCACCCGGTACACAAAACGGGCAGGTCTTCCGCTTGCGCG
GCAAGGGGATGCCGTCGCTGCGTACTGGTCAGCGCGGTGACCTCCTGGTCAAGGTCAAAGTGATCCTGCCGACTAATCTC
ACCGAGGAAGAGCGACGCCTCTTCGAGCGACTTCGCGAACTCCGTCAGGTTCGCACGCGCGCCTGA

Upstream 100 bases:

>100_bases
GGGCCCGATCCTGCACGACGCAAAGGGGCAGGACTTGCTACGGATCGACTCAACCTCTATACTCGAAGTCGGAACGTGGC
AGATTGGGTGACGGGCGACG

Downstream 100 bases:

>100_bases
TCGCCCTGGCGATGCTATAGTTCACCGGGCAGCATCGCCCGGAGCGACCGAGCTGACGAGGAGTCTACGCGATGCCAGTC
ACGATCGTTCTCGGCGGCCA

Product: chaperone protein dnaJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MEFKDYYKILGVPRDADQETIRKAYLRLARKYHPDVNKSPDAEEKFKEINEAYEVLRDPEKRARYDRFGADWERYQQAAG
AQGTTTDFEEWFFGTRDRAQRERRRTSDFSDFFDLLFGDLGDFFVTTGERIRTRARPERGQDYEHPIEVTLREAYRGATR
RIDVKIDERCPACNGTGLNGRGICRVCGGSGYVTRTKTLEVKIPAGVRDGSRIRIAGQGGPGVNGGPPGDLYLRVHLLPD
PQFALEGDNLRTEVEVPLYTAILGGEVTVPTLDRPVVLRIPPGTQNGQVFRLRGKGMPSLRTGQRGDLLVKVKVILPTNL
TEEERRLFERLRELRQVRTRA

Sequences:

>Translated_341_residues
MEFKDYYKILGVPRDADQETIRKAYLRLARKYHPDVNKSPDAEEKFKEINEAYEVLRDPEKRARYDRFGADWERYQQAAG
AQGTTTDFEEWFFGTRDRAQRERRRTSDFSDFFDLLFGDLGDFFVTTGERIRTRARPERGQDYEHPIEVTLREAYRGATR
RIDVKIDERCPACNGTGLNGRGICRVCGGSGYVTRTKTLEVKIPAGVRDGSRIRIAGQGGPGVNGGPPGDLYLRVHLLPD
PQFALEGDNLRTEVEVPLYTAILGGEVTVPTLDRPVVLRIPPGTQNGQVFRLRGKGMPSLRTGQRGDLLVKVKVILPTNL
TEEERRLFERLRELRQVRTRA
>Mature_341_residues
MEFKDYYKILGVPRDADQETIRKAYLRLARKYHPDVNKSPDAEEKFKEINEAYEVLRDPEKRARYDRFGADWERYQQAAG
AQGTTTDFEEWFFGTRDRAQRERRRTSDFSDFFDLLFGDLGDFFVTTGERIRTRARPERGQDYEHPIEVTLREAYRGATR
RIDVKIDERCPACNGTGLNGRGICRVCGGSGYVTRTKTLEVKIPAGVRDGSRIRIAGQGGPGVNGGPPGDLYLRVHLLPD
PQFALEGDNLRTEVEVPLYTAILGGEVTVPTLDRPVVLRIPPGTQNGQVFRLRGKGMPSLRTGQRGDLLVKVKVILPTNL
TEEERRLFERLRELRQVRTRA

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG0484

COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI205360838, Length=377, Percent_Identity=30.2387267904509, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI205360840, Length=377, Percent_Identity=30.2387267904509, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI201862587, Length=359, Percent_Identity=32.5905292479109, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI4504511, Length=379, Percent_Identity=30.6068601583113, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI201862518, Length=359, Percent_Identity=32.5905292479109, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI56549115, Length=359, Percent_Identity=32.5905292479109, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI6631085, Length=352, Percent_Identity=31.8181818181818, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI5031741, Length=364, Percent_Identity=30.7692307692308, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI7706495, Length=350, Percent_Identity=33.7142857142857, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI5453690, Length=356, Percent_Identity=30.0561797752809, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI194328760, Length=363, Percent_Identity=28.9256198347107, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI194328758, Length=363, Percent_Identity=28.9256198347107, Blast_Score=124, Evalue=9e-29,
Organism=Homo sapiens, GI39204547, Length=349, Percent_Identity=28.080229226361, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI9558755, Length=120, Percent_Identity=44.1666666666667, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI194306642, Length=119, Percent_Identity=42.8571428571429, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI194306640, Length=119, Percent_Identity=42.8571428571429, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI194328762, Length=324, Percent_Identity=25, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI56687498, Length=65, Percent_Identity=55.3846153846154, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI72534740, Length=101, Percent_Identity=40.5940594059406, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI47777312, Length=121, Percent_Identity=44.6280991735537, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI22749377, Length=66, Percent_Identity=53.030303030303, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI27151736, Length=136, Percent_Identity=40.4411764705882, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI88501736, Length=136, Percent_Identity=41.9117647058824, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4885495, Length=66, Percent_Identity=54.5454545454545, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI23503241, Length=71, Percent_Identity=53.5211267605634, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI21553335, Length=69, Percent_Identity=52.1739130434783, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI17388799, Length=66, Percent_Identity=54.5454545454545, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI45504382, Length=65, Percent_Identity=47.6923076923077, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI29126218, Length=65, Percent_Identity=50.7692307692308, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI24308127, Length=95, Percent_Identity=37.8947368421053, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI217035105, Length=73, Percent_Identity=43.8356164383562, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI68077168, Length=66, Percent_Identity=51.5151515151515, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI68077166, Length=66, Percent_Identity=51.5151515151515, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI21361912, Length=62, Percent_Identity=48.3870967741936, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1786197, Length=373, Percent_Identity=41.5549597855228, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1787235, Length=332, Percent_Identity=40.3614457831325, Blast_Score=213, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17553096, Length=369, Percent_Identity=29.5392953929539, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17553098, Length=379, Percent_Identity=29.023746701847, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17534355, Length=356, Percent_Identity=28.9325842696629, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17507263, Length=364, Percent_Identity=28.5714285714286, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI212645553, Length=349, Percent_Identity=28.080229226361, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17563890, Length=379, Percent_Identity=27.7044854881267, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI115532378, Length=67, Percent_Identity=56.7164179104478, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI115532476, Length=66, Percent_Identity=53.030303030303, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17538236, Length=83, Percent_Identity=44.578313253012, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86562985, Length=62, Percent_Identity=43.5483870967742, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17554644, Length=66, Percent_Identity=48.4848484848485, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324265, Length=378, Percent_Identity=31.7460317460317, Blast_Score=145, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6321094, Length=416, Percent_Identity=27.6442307692308, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6323870, Length=381, Percent_Identity=27.2965879265092, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6323119, Length=411, Percent_Identity=25.3041362530414, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6323813, Length=124, Percent_Identity=41.1290322580645, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6322388, Length=69, Percent_Identity=52.1739130434783, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324321, Length=68, Percent_Identity=47.0588235294118, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320888, Length=68, Percent_Identity=47.0588235294118, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI45552813, Length=372, Percent_Identity=29.0322580645161, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI45549272, Length=372, Percent_Identity=29.0322580645161, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI45552811, Length=372, Percent_Identity=29.0322580645161, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI85726398, Length=365, Percent_Identity=30.1369863013699, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI20129487, Length=352, Percent_Identity=31.25, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24584014, Length=352, Percent_Identity=31.25, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI18858081, Length=355, Percent_Identity=30.9859154929577, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI19920464, Length=338, Percent_Identity=28.698224852071, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24658562, Length=356, Percent_Identity=31.7415730337079, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24658555, Length=356, Percent_Identity=31.7415730337079, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI28574949, Length=352, Percent_Identity=28.9772727272727, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24646562, Length=365, Percent_Identity=29.8630136986301, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24646560, Length=365, Percent_Identity=29.8630136986301, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24646558, Length=365, Percent_Identity=29.8630136986301, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24646556, Length=365, Percent_Identity=29.8630136986301, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI21357547, Length=365, Percent_Identity=29.8630136986301, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24668492, Length=66, Percent_Identity=56.0606060606061, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17648033, Length=81, Percent_Identity=48.1481481481481, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24641698, Length=63, Percent_Identity=52.3809523809524, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24641696, Length=63, Percent_Identity=52.3809523809524, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24654066, Length=95, Percent_Identity=45.2631578947368, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24654070, Length=95, Percent_Identity=45.2631578947368, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24654068, Length=95, Percent_Identity=45.2631578947368, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24654072, Length=95, Percent_Identity=45.2631578947368, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24584630, Length=81, Percent_Identity=48.1481481481481, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21358273, Length=68, Percent_Identity=50, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24643995, Length=68, Percent_Identity=50, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17737735, Length=65, Percent_Identity=49.2307692307692, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574723, Length=65, Percent_Identity=49.2307692307692, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24668523, Length=65, Percent_Identity=49.2307692307692, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161077138, Length=66, Percent_Identity=53.030303030303, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 38906; Mature: 38906

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFKDYYKILGVPRDADQETIRKAYLRLARKYHPDVNKSPDAEEKFKEINEAYEVLRDPE
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCHH
KRARYDRFGADWERYQQAAGAQGTTTDFEEWFFGTRDRAQRERRRTSDFSDFFDLLFGDL
HHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHH
GDFFVTTGERIRTRARPERGQDYEHPIEVTLREAYRGATRRIDVKIDERCPACNGTGLNG
HHHEECCCHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCC
RGICRVCGGSGYVTRTKTLEVKIPAGVRDGSRIRIAGQGGPGVNGGPPGDLYLRVHLLPD
CCEEEEECCCCEEEEEEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCC
PQFALEGDNLRTEVEVPLYTAILGGEVTVPTLDRPVVLRIPPGTQNGQVFRLRGKGMPSL
CCEEECCCCCEEEEECCEEEEEECCCEEECCCCCCEEEEECCCCCCCCEEEEECCCCCCC
RTGQRGDLLVKVKVILPTNLTEEERRLFERLRELRQVRTRA
CCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEFKDYYKILGVPRDADQETIRKAYLRLARKYHPDVNKSPDAEEKFKEINEAYEVLRDPE
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCHH
KRARYDRFGADWERYQQAAGAQGTTTDFEEWFFGTRDRAQRERRRTSDFSDFFDLLFGDL
HHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHH
GDFFVTTGERIRTRARPERGQDYEHPIEVTLREAYRGATRRIDVKIDERCPACNGTGLNG
HHHEECCCHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCC
RGICRVCGGSGYVTRTKTLEVKIPAGVRDGSRIRIAGQGGPGVNGGPPGDLYLRVHLLPD
CCEEEEECCCCEEEEEEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCC
PQFALEGDNLRTEVEVPLYTAILGGEVTVPTLDRPVVLRIPPGTQNGQVFRLRGKGMPSL
CCEEECCCCCEEEEECCEEEEEECCCEEECCCCCCEEEEECCCCCCCCEEEEECCCCCCC
RTGQRGDLLVKVKVILPTNLTEEERRLFERLRELRQVRTRA
CCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]