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The map label for this gene is soxB [H]

Identifier: 221632158

GI number: 221632158

Start: 129807

End: 130970

Strand: Reverse

Name: soxB [H]

Synonym: trd_0123

Alternate gene names: 221632158

Gene position: 130970-129807 (Counterclockwise)

Preceding gene: 221632159

Following gene: 221632157

Centisome position: 6.54

GC content: 62.37

Gene sequence:

>1164_bases
ATGAGTAGCGACGACGTCGTGATCGTCGGCGGTGGAAATCTCGGTCTCTGGACCGCCTACCACCTGGCCCAGCGAGGGGT
ACGTCGGATCCTGGTCTGCGAACGGTATTGGGCCGGGTACGGCGCCACTGTGCGCTCGGCTGGGATCATGCGGCAGCAAG
GCGGTTCAGAAACCGCCGTGAAACTCGGGAAATGGTCGCGCGAGCTGTACCGAAAGCTGGGCCAGGAACTCGGGCTGGAC
AGTGGCTTCCGTGAAGTCGGCTACTACGTCGTCGCCTCTAGTCCCATGGAAAAAGCGGTGTTCCAGCGCCTGGTAGAACT
GCGAACTGCTCACGGCGTTCCGAACGAATGGTTGGATCCAGAGGATCTCGCTCGGCGCCTGCCCTATGTCGACTGGAGCC
GATTCGCCGGTGCGACTTACACGCCCAACGATGGCTATGTCGAGCCAGCGATCATCGTTCGCAACATCGTCATGGCCGTG
CGTGCAGCCGGCGTCGAGCTGCTCGAGCAGTGCGAGGTCCAGGGGATCGAGCCGCTCACCAGTGGTTATCGAGTCGAGAC
GTCGCGAGGCGTATTCGAGACGGAACGGGTGATCGATGCTGGCGGCCCACGCGGTGCCCGGCGGATCGCCGAGTTCGTGG
GGATCGATGTACCGGTGGCTGCTTCCCGGCACATGGTGATCTCCTTCCCGGAGCGACCGCCCGACATGCCGGCGAACTTT
CCGATGATGTTCGTTCTGGCTGCTGGCTTTTACCTACGCCCGGACGAGCAGGGAGTGCTCTTGGGGTTTTCGAATCCCTT
GGAGCAACCGGACCCGAGCGATCGCTACCTTCTGGAATTCGACTGGGACTATTTCGAGAAGCTCAAGCCGGAGTGGGAAG
CGACCATCCCCAGCTTGGCAGGGAAGGCGATCGGTCGAGCTTGGACCGGATCGATCGATTACACACCGGATCAGCTTCCC
ATCATCGACGAGCCGCGCTTCGGCTTCTACGTGCTCGCCGCGGGTGGACATGGGATCATGTGGGGGCCGGCTCTCGGCAT
GAAGATGGCGGAATTGGTCACGGAGGAGCGCTTGAGCGATCTCGACCCGGAGGAAGTGCGCTTGCGGCGCTTTACGGAAG
GTCGGATGGCCACCGACGCCATTCATCTCCCCTTCCCGCACTGA

Upstream 100 bases:

>100_bases
CATTCTTCCGCTGTGTCGAACGGACCCTGCTCAGCGAACAGCCGGTCGAGACGCACGAGTGAACGAGAGTGCCTCGCGCA
GCAGGGAAAGGAGCGAGCAC

Downstream 100 bases:

>100_bases
GCGCCCGGTCGACTCTCCCCAAACCGACCGTCAGCGGGGGGCAGCGTGGTCCATCACGCTGTCCCCCGCTCGATTGGTCG
AGGTGCTTCCGAGAACCGGT

Product: putative oxidoreductase protein

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSSDDVVIVGGGNLGLWTAYHLAQRGVRRILVCERYWAGYGATVRSAGIMRQQGGSETAVKLGKWSRELYRKLGQELGLD
SGFREVGYYVVASSPMEKAVFQRLVELRTAHGVPNEWLDPEDLARRLPYVDWSRFAGATYTPNDGYVEPAIIVRNIVMAV
RAAGVELLEQCEVQGIEPLTSGYRVETSRGVFETERVIDAGGPRGARRIAEFVGIDVPVAASRHMVISFPERPPDMPANF
PMMFVLAAGFYLRPDEQGVLLGFSNPLEQPDPSDRYLLEFDWDYFEKLKPEWEATIPSLAGKAIGRAWTGSIDYTPDQLP
IIDEPRFGFYVLAAGGHGIMWGPALGMKMAELVTEERLSDLDPEEVRLRRFTEGRMATDAIHLPFPH

Sequences:

>Translated_387_residues
MSSDDVVIVGGGNLGLWTAYHLAQRGVRRILVCERYWAGYGATVRSAGIMRQQGGSETAVKLGKWSRELYRKLGQELGLD
SGFREVGYYVVASSPMEKAVFQRLVELRTAHGVPNEWLDPEDLARRLPYVDWSRFAGATYTPNDGYVEPAIIVRNIVMAV
RAAGVELLEQCEVQGIEPLTSGYRVETSRGVFETERVIDAGGPRGARRIAEFVGIDVPVAASRHMVISFPERPPDMPANF
PMMFVLAAGFYLRPDEQGVLLGFSNPLEQPDPSDRYLLEFDWDYFEKLKPEWEATIPSLAGKAIGRAWTGSIDYTPDQLP
IIDEPRFGFYVLAAGGHGIMWGPALGMKMAELVTEERLSDLDPEEVRLRRFTEGRMATDAIHLPFPH
>Mature_386_residues
SSDDVVIVGGGNLGLWTAYHLAQRGVRRILVCERYWAGYGATVRSAGIMRQQGGSETAVKLGKWSRELYRKLGQELGLDS
GFREVGYYVVASSPMEKAVFQRLVELRTAHGVPNEWLDPEDLARRLPYVDWSRFAGATYTPNDGYVEPAIIVRNIVMAVR
AAGVELLEQCEVQGIEPLTSGYRVETSRGVFETERVIDAGGPRGARRIAEFVGIDVPVAASRHMVISFPERPPDMPANFP
MMFVLAAGFYLRPDEQGVLLGFSNPLEQPDPSDRYLLEFDWDYFEKLKPEWEATIPSLAGKAIGRAWTGSIDYTPDQLPI
IDEPRFGFYVLAAGGHGIMWGPALGMKMAELVTEERLSDLDPEEVRLRRFTEGRMATDAIHLPFPH

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=385, Percent_Identity=28.8311688311688, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI21361378, Length=385, Percent_Identity=28.8311688311688, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI24797151, Length=383, Percent_Identity=25.3263707571802, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI194306651, Length=381, Percent_Identity=25.4593175853018, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI32563613, Length=404, Percent_Identity=25.2475247524752, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71994045, Length=374, Percent_Identity=21.9251336898396, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994052, Length=381, Percent_Identity=21.7847769028871, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI20130091, Length=382, Percent_Identity=29.3193717277487, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571104, Length=373, Percent_Identity=26.8096514745308, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI20129729, Length=389, Percent_Identity=25.4498714652956, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 43199; Mature: 43068

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDDVVIVGGGNLGLWTAYHLAQRGVRRILVCERYWAGYGATVRSAGIMRQQGGSETAV
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHCCCCHHHH
KLGKWSRELYRKLGQELGLDSGFREVGYYVVASSPMEKAVFQRLVELRTAHGVPNEWLDP
HHHHHHHHHHHHHHHHCCCCCCCHHHCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCH
EDLARRLPYVDWSRFAGATYTPNDGYVEPAIIVRNIVMAVRAAGVELLEQCEVQGIEPLT
HHHHHHCCCCCHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHC
SGYRVETSRGVFETERVIDAGGPRGARRIAEFVGIDVPVAASRHMVISFPERPPDMPANF
CCEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCC
PMMFVLAAGFYLRPDEQGVLLGFSNPLEQPDPSDRYLLEFDWDYFEKLKPEWEATIPSLA
HHHHHHHCCCEECCCCCEEEEECCCCCCCCCCCCCEEEEECHHHHHHCCCCHHHHHHHHH
GKAIGRAWTGSIDYTPDQLPIIDEPRFGFYVLAAGGHGIMWGPALGMKMAELVTEERLSD
HHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHC
LDPEEVRLRRFTEGRMATDAIHLPFPH
CCHHHHHHHHHHCCCEEECEEECCCCC
>Mature Secondary Structure 
SSDDVVIVGGGNLGLWTAYHLAQRGVRRILVCERYWAGYGATVRSAGIMRQQGGSETAV
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHCCCCHHHH
KLGKWSRELYRKLGQELGLDSGFREVGYYVVASSPMEKAVFQRLVELRTAHGVPNEWLDP
HHHHHHHHHHHHHHHHCCCCCCCHHHCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCH
EDLARRLPYVDWSRFAGATYTPNDGYVEPAIIVRNIVMAVRAAGVELLEQCEVQGIEPLT
HHHHHHCCCCCHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHC
SGYRVETSRGVFETERVIDAGGPRGARRIAEFVGIDVPVAASRHMVISFPERPPDMPANF
CCEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCC
PMMFVLAAGFYLRPDEQGVLLGFSNPLEQPDPSDRYLLEFDWDYFEKLKPEWEATIPSLA
HHHHHHHCCCEECCCCCEEEEECCCCCCCCCCCCCEEEEECHHHHHHCCCCHHHHHHHHH
GKAIGRAWTGSIDYTPDQLPIIDEPRFGFYVLAAGGHGIMWGPALGMKMAELVTEERLSD
HHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHC
LDPEEVRLRRFTEGRMATDAIHLPFPH
CCHHHHHHHHHHCCCEEECEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7543100; 1939012; 3202887; 7692961 [H]