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The map label for this gene is uhpB [H]

Identifier: 22127902

GI number: 22127902

Start: 4468779

End: 4469579

Strand: Reverse

Name: uhpB [H]

Synonym: y4032

Alternate gene names: 22127902

Gene position: 4469579-4468779 (Counterclockwise)

Preceding gene: 22127903

Following gene: 22127901

Centisome position: 97.15

GC content: 49.69

Gene sequence:

>801_bases
ATGATACAGCGCTTGGTGATGCTGCTGGCGTTATTCTTTATTTATTTTACTGCGGCTTTCTGCCTGTGGGCTATAGGGAC
ACAATTAGCTGATCGGGCTTTACAGTCGCTGCTGTTGTTCCCATTTGGTCTGCGTATGGGGATTTTATTACAAAGTCCAC
GTGCTTACTGGCCTGGCATTTTACTGGGTGATGTCCTGTTGTGGTGGCTATTAGCCGATCAATTCGATGATTTATATCAG
TTGTGGGTCGCCTTGCCGCTGTTGTTATTGACCACCTTATTGGCCCTTTTTGCCTCCCCGTGGTTATTGCGCCATCAGCA
AAATGAGAGCGAATGGCAATGGCCGTTAATGCAGGGGGGCGTTATCACGGTTGCCGCGCTAATACAGGCGTTGGGGTGGC
AGATAGCCAGTGGGCAGGGCGCAATGGCGCTCTTATTAGGGTTGGTTGGTGGCTTTACCATCGCGCCTACCTGCCTGCTG
CTGTGGCACTATCTGGCACGTCAAATCTGGTTACCGCTTGAACCTGGGTTGATACATAAACCGGTTAACCTGCGGTTGCG
GCATATCCTGTGGTATCTACTGCTATTTGCCATCAGTATCTGGTTACAGTACCAAGTGACTGAAACAGATTTACGCTTAT
TTGTACCGTTCTGTTTGGCGATCCCCATCGTGTTTATGGCATATCGCTATGGCTGGCAGGGGGCGTTGGCGGCCACGTTA
CTCAATGGTGTAGTGCTCTTGATTAATACACCTGAACCCCTTGAATCTCATCGTGGCTTGCTACTTTCACTGTTGGTGTA
A

Upstream 100 bases:

>100_bases
TCGGGCTATCGCCAAAAACGGTCCATGTCCACCGGGCTAATTTATTTGCCAAGCTAGGCATCAGCAATAATGTTGAGCTG
GCTAAGAAAGTACTGAATCT

Downstream 100 bases:

>100_bases
CGAACGGTGCAATAGTGATCCACACCCAACGCCTGAAATCAGATCCAGGGGGTAATCTGCTCTCCTGATTCAGGAGAGTT
TATGGTCACTTTTGAGACAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MIQRLVMLLALFFIYFTAAFCLWAIGTQLADRALQSLLLFPFGLRMGILLQSPRAYWPGILLGDVLLWWLLADQFDDLYQ
LWVALPLLLLTTLLALFASPWLLRHQQNESEWQWPLMQGGVITVAALIQALGWQIASGQGAMALLLGLVGGFTIAPTCLL
LWHYLARQIWLPLEPGLIHKPVNLRLRHILWYLLLFAISIWLQYQVTETDLRLFVPFCLAIPIVFMAYRYGWQGALAATL
LNGVVLLINTPEPLESHRGLLLSLLV

Sequences:

>Translated_266_residues
MIQRLVMLLALFFIYFTAAFCLWAIGTQLADRALQSLLLFPFGLRMGILLQSPRAYWPGILLGDVLLWWLLADQFDDLYQ
LWVALPLLLLTTLLALFASPWLLRHQQNESEWQWPLMQGGVITVAALIQALGWQIASGQGAMALLLGLVGGFTIAPTCLL
LWHYLARQIWLPLEPGLIHKPVNLRLRHILWYLLLFAISIWLQYQVTETDLRLFVPFCLAIPIVFMAYRYGWQGALAATL
LNGVVLLINTPEPLESHRGLLLSLLV
>Mature_266_residues
MIQRLVMLLALFFIYFTAAFCLWAIGTQLADRALQSLLLFPFGLRMGILLQSPRAYWPGILLGDVLLWWLLADQFDDLYQ
LWVALPLLLLTTLLALFASPWLLRHQQNESEWQWPLMQGGVITVAALIQALGWQIASGQGAMALLLGLVGGFTIAPTCLL
LWHYLARQIWLPLEPGLIHKPVNLRLRHILWYLLLFAISIWLQYQVTETDLRLFVPFCLAIPIVFMAYRYGWQGALAATL
LNGVVLLINTPEPLESHRGLLLSLLV

Specific function: Member of the two-component regulatory system uhpB/uhpA involved in the regulation of the uptake of hexose phosphates. UhpB functions as a membrane-associated protein kinase that phosphorylates uhpA in response to environmental signals [H]

COG id: COG3851

COG function: function code T; Signal transduction histidine kinase, glucose-6-phosphate specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=251, Percent_Identity=46.6135458167331, Blast_Score=169, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR007895
- InterPro:   IPR011712
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3; PF05231 MASE1 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 30226; Mature: 30226

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQRLVMLLALFFIYFTAAFCLWAIGTQLADRALQSLLLFPFGLRMGILLQSPRAYWPGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
LLGDVLLWWLLADQFDDLYQLWVALPLLLLTTLLALFASPWLLRHQQNESEWQWPLMQGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHCC
VITVAALIQALGWQIASGQGAMALLLGLVGGFTIAPTCLLLWHYLARQIWLPLEPGLIHK
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCEEC
PVNLRLRHILWYLLLFAISIWLQYQVTETDLRLFVPFCLAIPIVFMAYRYGWQGALAATL
CHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LNGVVLLINTPEPLESHRGLLLSLLV
HCCEEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIQRLVMLLALFFIYFTAAFCLWAIGTQLADRALQSLLLFPFGLRMGILLQSPRAYWPGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
LLGDVLLWWLLADQFDDLYQLWVALPLLLLTTLLALFASPWLLRHQQNESEWQWPLMQGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHCC
VITVAALIQALGWQIASGQGAMALLLGLVGGFTIAPTCLLLWHYLARQIWLPLEPGLIHK
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCEEC
PVNLRLRHILWYLLLFAISIWLQYQVTETDLRLFVPFCLAIPIVFMAYRYGWQGALAATL
CHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LNGVVLLINTPEPLESHRGLLLSLLV
HCCEEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3301805; 1569007; 7686882; 9278503 [H]