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The map label for this gene is cytR [H]

Identifier: 22127311

GI number: 22127311

Start: 3823480

End: 3824499

Strand: Reverse

Name: cytR [H]

Synonym: y3436

Alternate gene names: 22127311

Gene position: 3824499-3823480 (Counterclockwise)

Preceding gene: 22127314

Following gene: 22127310

Centisome position: 83.13

GC content: 45.39

Gene sequence:

>1020_bases
ATGAATAAAAAAACGAAAGTGACTATGAGCCACATTGCGGCCAAAGCGGGAGTATCACAATCAACAGTTTCATTGGTGCT
AAACGGCTCTTACAGCATCAAACTGGCAGATGACACCAGAGAAAAAGTCCTGCGTATTGCTCAGGAGATGGGCTATGTCC
ATAAAGCCGTGGAACGGCCCATTGCCAGAGATAAAATAGCATTAATTATTAATGGGCTAATAAACCATGATCCTTTCATT
GAAGCGATCAGTGCTGTTCAACAGGCAGCCTGGCAACACAACAAGTTATTGGCGATTTTTGATCAGGAAAATGAACCAGA
GCACTGCGCAGCACTTGAAGAGGAAATCTGTCGAGGAGGTTATCAGGGGGTAATTTACGCCTCTTGCATGACTAGCCAGT
TAGCGCCGATGTTTCGTAATCTGTCCATCCCAATGGTAATGCTGAATGGTTATTGCCCTGAGTTACCTGATGTTCCCTGT
ATTTTACCCGCAGATAAAATTGGCGCTTATAAGGCTACCAGCCATTTATTGCAACAGGGATATAAACGGATTGCCATTCT
GGCTGGCGAACTGTGGATGGATGCCGCCAACGACCGTATTAGTGGCTACCGGCAGGCACTCATCAACCATGATATTTGCC
CTGATGAAGGTTATATCCAGGTGACAAACTGGTCATTGAAGGAAGCGTATAAAAAAACACTGGAATTGCTGGCACTCACT
GCCAGACCAGAAGCCATTTTCTGCAGTAGTGACTATATAGCACTCGGGTGTTATCAGGCGATTTTGTCACAAGGGTTGCG
CATTCCCGATGATATCGCCGTCGTGGGCTATGATAATCAAAGTATTTCTTCCGAACTGTCGCCAGAATTAAGCTCAGTAA
ACTTACCTTACGGTGAAATGGGCGAAATGGCGCTGCATACCTTACTCAACATCACGCAGCAGCAACCCTTGCTGTCATTG
AAAATGAAGGTAGAAGGCGAGTTGGTTATCCGACAGTCTTCAATAAGACCAGAGAAATAG

Upstream 100 bases:

>100_bases
AATGAGTGAGATATCAGCCCGGCAGCCCCTGATGAACAGTCCTGCTAGCTAAAATCTGTTAGTATAAAAAAAGATGAAAT
ATAGCCAGTATGAGTAAAAT

Downstream 100 bases:

>100_bases
CCTACCCCGCGCCAGCCTCCATTTAATTGGGCACGGCTCCTAATTGAGAATAACGCCTCCTCTCAATTGAGAACAATGCC
CACGTTCAATTAAGAACAGC

Product: transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MNKKTKVTMSHIAAKAGVSQSTVSLVLNGSYSIKLADDTREKVLRIAQEMGYVHKAVERPIARDKIALIINGLINHDPFI
EAISAVQQAAWQHNKLLAIFDQENEPEHCAALEEEICRGGYQGVIYASCMTSQLAPMFRNLSIPMVMLNGYCPELPDVPC
ILPADKIGAYKATSHLLQQGYKRIAILAGELWMDAANDRISGYRQALINHDICPDEGYIQVTNWSLKEAYKKTLELLALT
ARPEAIFCSSDYIALGCYQAILSQGLRIPDDIAVVGYDNQSISSELSPELSSVNLPYGEMGEMALHTLLNITQQQPLLSL
KMKVEGELVIRQSSIRPEK

Sequences:

>Translated_339_residues
MNKKTKVTMSHIAAKAGVSQSTVSLVLNGSYSIKLADDTREKVLRIAQEMGYVHKAVERPIARDKIALIINGLINHDPFI
EAISAVQQAAWQHNKLLAIFDQENEPEHCAALEEEICRGGYQGVIYASCMTSQLAPMFRNLSIPMVMLNGYCPELPDVPC
ILPADKIGAYKATSHLLQQGYKRIAILAGELWMDAANDRISGYRQALINHDICPDEGYIQVTNWSLKEAYKKTLELLALT
ARPEAIFCSSDYIALGCYQAILSQGLRIPDDIAVVGYDNQSISSELSPELSSVNLPYGEMGEMALHTLLNITQQQPLLSL
KMKVEGELVIRQSSIRPEK
>Mature_339_residues
MNKKTKVTMSHIAAKAGVSQSTVSLVLNGSYSIKLADDTREKVLRIAQEMGYVHKAVERPIARDKIALIINGLINHDPFI
EAISAVQQAAWQHNKLLAIFDQENEPEHCAALEEEICRGGYQGVIYASCMTSQLAPMFRNLSIPMVMLNGYCPELPDVPC
ILPADKIGAYKATSHLLQQGYKRIAILAGELWMDAANDRISGYRQALINHDICPDEGYIQVTNWSLKEAYKKTLELLALT
ARPEAIFCSSDYIALGCYQAILSQGLRIPDDIAVVGYDNQSISSELSPELSSVNLPYGEMGEMALHTLLNITQQQPLLSL
KMKVEGELVIRQSSIRPEK

Specific function: Transcriptional repressor for the ribose rbsDACBK operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=344, Percent_Identity=31.1046511627907, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1790194, Length=333, Percent_Identity=28.2282282282282, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787948, Length=335, Percent_Identity=25.9701492537313, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789202, Length=336, Percent_Identity=27.9761904761905, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787580, Length=318, Percent_Identity=27.0440251572327, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1788474, Length=305, Percent_Identity=29.8360655737705, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789068, Length=347, Percent_Identity=25.6484149855908, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786540, Length=348, Percent_Identity=27.0114942528736, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1787906, Length=289, Percent_Identity=27.681660899654, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI48994940, Length=325, Percent_Identity=23.3846153846154, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790715, Length=317, Percent_Identity=21.7665615141956, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37534; Mature: 37534

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKTKVTMSHIAAKAGVSQSTVSLVLNGSYSIKLADDTREKVLRIAQEMGYVHKAVERP
CCCCCEEHHHHHHHHCCCCCCEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHCC
IARDKIALIINGLINHDPFIEAISAVQQAAWQHNKLLAIFDQENEPEHCAALEEEICRGG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCC
YQGVIYASCMTSQLAPMFRNLSIPMVMLNGYCPELPDVPCILPADKIGAYKATSHLLQQG
CCCEEEHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEECCHHHCCHHHHHHHHHHHH
YKRIAILAGELWMDAANDRISGYRQALINHDICPDEGYIQVTNWSLKEAYKKTLELLALT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHC
ARPEAIFCSSDYIALGCYQAILSQGLRIPDDIAVVGYDNQSISSELSPELSSVNLPYGEM
CCCCEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHCCCCHHCCCCCCCHH
GEMALHTLLNITQQQPLLSLKMKVEGELVIRQSSIRPEK
HHHHHHHHHHHHHCCCCEEEEEEECCEEEEEECCCCCCC
>Mature Secondary Structure
MNKKTKVTMSHIAAKAGVSQSTVSLVLNGSYSIKLADDTREKVLRIAQEMGYVHKAVERP
CCCCCEEHHHHHHHHCCCCCCEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHCC
IARDKIALIINGLINHDPFIEAISAVQQAAWQHNKLLAIFDQENEPEHCAALEEEICRGG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCC
YQGVIYASCMTSQLAPMFRNLSIPMVMLNGYCPELPDVPCILPADKIGAYKATSHLLQQG
CCCEEEHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEECCHHHCCHHHHHHHHHHHH
YKRIAILAGELWMDAANDRISGYRQALINHDICPDEGYIQVTNWSLKEAYKKTLELLALT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHC
ARPEAIFCSSDYIALGCYQAILSQGLRIPDDIAVVGYDNQSISSELSPELSSVNLPYGEM
CCCCEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHCCCCHHCCCCCCCHH
GEMALHTLLNITQQQPLLSLKMKVEGELVIRQSSIRPEK
HHHHHHHHHHHHHCCCCEEEEEEECCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]