Click here to switch to the map view.

The map label for this gene is gpmA [H]

Identifier: 22126924

GI number: 22126924

Start: 3355653

End: 3356489

Strand: Direct

Name: gpmA [H]

Synonym: y3048

Alternate gene names: 22126924

Gene position: 3355653-3356489 (Clockwise)

Preceding gene: 22126923

Following gene: 22126926

Centisome position: 72.94

GC content: 47.19

Gene sequence:

>837_bases
GTGATTCGGCTGATTGAGCGCAGCCAACGCACATGCAGCTTGAAGTATGACGGGCATATACCAAACTTAATTGGAGTCAA
CGTTATGGCAGTAACTAAGCTAGTTTTGGTACGACACGGCGAAAGTCAATGGAACAACGAAAACCGCTTCACCGGTTGGT
ATGATGTTGATCTGTCTGAAAAAGGCCGTTCTGAAGCAAAGGCAGCGGGTAAGCTGTTAAAAGATGAAGGCTTCACTTTT
GATTTCGCCTACACCTCAGTATTAAAACGCGCTATCCACACCTTGTGGAACATTTTGGATGAATTAGATCAGGCATGGCT
GCCAACAGAAAAAACCTGGAAGCTTAACGAGCGTCACTACGGCGCACTGCAAGGCCTGAATAAATCTGAAACGGCTGAAA
AATACGGCGATGAGCAGGTTAAGCAATGGCGTCGTGGCTTTGCCATCACCCCTCCAGCACTGGAGAAAAGCGATGAGCGT
TTCCCAGGCCATGACCCACGTTATGCAAAATTGACTGATGCTGAGCTGCCAACCACAGAAAGCTTGGCGCTGACTATTGA
ACGCGTGATTCCCTACTGGAATGACGTTATCAAACCACGTATTGCCAGCGGTGAACGCGTAATTATTGCTGCTCACGGTA
ACTCTTTACGTGCATTGGTAAAATATCTGGATGATCTGGGCGAAGACGAAATTCTTGAGCTGAACATCCCAACTGGCGTG
CCATTAGTGTATGAGTTTGATGAGAACTTCAAGCCTATCAAACACTACTATCTGGGTAACGCTGATGAAATCGCCGCTAA
AGCTGCAGCGGTTGCTAACCAGGGTAAAGCGAAGTAA

Upstream 100 bases:

>100_bases
AATGATAATAATTATCATTGAATGTGTATTTATTACCCAAAATAATTCGAGTTGCAGGAAGGCGGCAAGCGAGAGAGTTC
CAATGAGCTTACTGGAGTAA

Downstream 100 bases:

>100_bases
TTAGCCCTGATTAACACAGTAAAAAAACCCCGTACATGAATAATGTCGGGGTTTTTTATTGACGGCTATGTGAATGCAGT
CAGCACTCCGTTACCAAAGC

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MIRLIERSQRTCSLKYDGHIPNLIGVNVMAVTKLVLVRHGESQWNNENRFTGWYDVDLSEKGRSEAKAAGKLLKDEGFTF
DFAYTSVLKRAIHTLWNILDELDQAWLPTEKTWKLNERHYGALQGLNKSETAEKYGDEQVKQWRRGFAITPPALEKSDER
FPGHDPRYAKLTDAELPTTESLALTIERVIPYWNDVIKPRIASGERVIIAAHGNSLRALVKYLDDLGEDEILELNIPTGV
PLVYEFDENFKPIKHYYLGNADEIAAKAAAVANQGKAK

Sequences:

>Translated_278_residues
MIRLIERSQRTCSLKYDGHIPNLIGVNVMAVTKLVLVRHGESQWNNENRFTGWYDVDLSEKGRSEAKAAGKLLKDEGFTF
DFAYTSVLKRAIHTLWNILDELDQAWLPTEKTWKLNERHYGALQGLNKSETAEKYGDEQVKQWRRGFAITPPALEKSDER
FPGHDPRYAKLTDAELPTTESLALTIERVIPYWNDVIKPRIASGERVIIAAHGNSLRALVKYLDDLGEDEILELNIPTGV
PLVYEFDENFKPIKHYYLGNADEIAAKAAAVANQGKAK
>Mature_278_residues
MIRLIERSQRTCSLKYDGHIPNLIGVNVMAVTKLVLVRHGESQWNNENRFTGWYDVDLSEKGRSEAKAAGKLLKDEGFTF
DFAYTSVLKRAIHTLWNILDELDQAWLPTEKTWKLNERHYGALQGLNKSETAEKYGDEQVKQWRRGFAITPPALEKSDER
FPGHDPRYAKLTDAELPTTESLALTIERVIPYWNDVIKPRIASGERVIIAAHGNSLRALVKYLDDLGEDEILELNIPTGV
PLVYEFDENFKPIKHYYLGNADEIAAKAAAVANQGKAK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=256, Percent_Identity=56.25, Blast_Score=295, Evalue=4e-80,
Organism=Homo sapiens, GI4505753, Length=253, Percent_Identity=56.5217391304348, Blast_Score=290, Evalue=7e-79,
Organism=Homo sapiens, GI71274132, Length=253, Percent_Identity=54.1501976284585, Blast_Score=277, Evalue=7e-75,
Organism=Homo sapiens, GI4502445, Length=256, Percent_Identity=46.484375, Blast_Score=251, Evalue=7e-67,
Organism=Homo sapiens, GI40353764, Length=256, Percent_Identity=46.484375, Blast_Score=251, Evalue=7e-67,
Organism=Homo sapiens, GI310129614, Length=165, Percent_Identity=56.969696969697, Blast_Score=190, Evalue=1e-48,
Organism=Escherichia coli, GI1786970, Length=250, Percent_Identity=88, Blast_Score=449, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6322697, Length=246, Percent_Identity=52.4390243902439, Blast_Score=246, Evalue=4e-66,
Organism=Saccharomyces cerevisiae, GI6324516, Length=302, Percent_Identity=31.4569536423841, Blast_Score=142, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6320183, Length=303, Percent_Identity=29.3729372937294, Blast_Score=126, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6324857, Length=129, Percent_Identity=31.7829457364341, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI85725270, Length=250, Percent_Identity=56.4, Blast_Score=275, Evalue=2e-74,
Organism=Drosophila melanogaster, GI85725272, Length=250, Percent_Identity=56.4, Blast_Score=275, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24650981, Length=250, Percent_Identity=56.4, Blast_Score=275, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24646216, Length=250, Percent_Identity=53.6, Blast_Score=275, Evalue=3e-74,
Organism=Drosophila melanogaster, GI28571817, Length=248, Percent_Identity=39.1129032258064, Blast_Score=180, Evalue=9e-46,
Organism=Drosophila melanogaster, GI28571815, Length=248, Percent_Identity=39.1129032258064, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24648979, Length=248, Percent_Identity=39.1129032258064, Blast_Score=180, Evalue=1e-45,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 31567; Mature: 31567

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLIERSQRTCSLKYDGHIPNLIGVNVMAVTKLVLVRHGESQWNNENRFTGWYDVDLSE
CCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEEEECCCCC
KGRSEAKAAGKLLKDEGFTFDFAYTSVLKRAIHTLWNILDELDQAWLPTEKTWKLNERHY
CCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHH
GALQGLNKSETAEKYGDEQVKQWRRGFAITPPALEKSDERFPGHDPRYAKLTDAELPTTE
HHHCCCCCHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCH
SLALTIERVIPYWNDVIKPRIASGERVIIAAHGNSLRALVKYLDDLGEDEILELNIPTGV
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCC
PLVYEFDENFKPIKHYYLGNADEIAAKAAAVANQGKAK
CEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIRLIERSQRTCSLKYDGHIPNLIGVNVMAVTKLVLVRHGESQWNNENRFTGWYDVDLSE
CCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEEEECCCCC
KGRSEAKAAGKLLKDEGFTFDFAYTSVLKRAIHTLWNILDELDQAWLPTEKTWKLNERHY
CCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHH
GALQGLNKSETAEKYGDEQVKQWRRGFAITPPALEKSDERFPGHDPRYAKLTDAELPTTE
HHHCCCCCHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCH
SLALTIERVIPYWNDVIKPRIASGERVIIAAHGNSLRALVKYLDDLGEDEILELNIPTGV
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCC
PLVYEFDENFKPIKHYYLGNADEIAAKAAAVANQGKAK
CEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA