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The map label for this gene is clpB [H]

Identifier: 22126578

GI number: 22126578

Start: 2981840

End: 2984479

Strand: Reverse

Name: clpB [H]

Synonym: y2699

Alternate gene names: 22126578

Gene position: 2984479-2981840 (Counterclockwise)

Preceding gene: 22126579

Following gene: 22126577

Centisome position: 64.87

GC content: 59.24

Gene sequence:

>2640_bases
ATGACAACGCATTCAGCACACTTATTACGTCGGTTAAATCCCTATTGCGCACAGGCACTGGCCGGTGCCGCCACCCTGTG
TCAGACCCGCGCCCATGCTGAGATCACTGTCGAACACTGGTTGTTAAAATTGCTGGAGCAGGGCGAAGGCGATATTACAG
TCATTGCCCGGCGTTATGAGTGGGACATGGACAGCCTGTGGCAGGGATTACTGTCCCATCTGGACACCTTGCCGCGCACG
GTACAGGGCAAACCTCAGTTGTCCGCCGCGTTACAGCAACTGATCAAAAACGCCTGGCTGGATGCCTCGTTGCAGGAAAA
TGCTGATGCGGTGCGCTCGGTTCATCTAATGGCAGCGCTGATTGCCACGCCGTCATTATTGGTCGCCGAGGCCGCCTGGC
CGTTGCTCAGCCTGAGCACCACTCAGCTACAGCGCCTGTTACCGCTGCTGGACAACCAGTCCGACGAACGCCCTGAGGTG
CAGCAGGCTGCGGCACTGGCCGACAGCCCGGTCAATCTGACCGATGAGGCCGCGACGGTTACCTCCGCCAGTGGTCAGCC
GCAACTGAATGACGCGCTGCAAGCGGCGCTGGATAAATTCACCCTCGACGTCACCGCCAAAGCCCGTGCCAACCAGATTG
ACCCGATTTTTGGCCGCGACAGCGAAATCCGCCAGATGATCGACATCCTGTCGCGCCGCCGTAAAAACAACCCGATTCTG
GTGGGTGAACCGGGTGTGGGGAAAACCGCGCTGGTTGAAGGGCTGGCACTGCGGATTGCCGACGGCAACGTACCGGACAG
CCTGAAAACCGTCAGTGTGCGCACACTGGATTTGGGTCTGTTACAGGCCGGGGCTGGGGTGAAAGGCGAATTCGAACAGC
GCCTGAAAAATGTTATCGAGGCGGTGCAACAATCCCCCAGCCCGGTGCTGCTGTTTATCGACGAAGCCCACACCATTATC
GGGGCCGGTAATCAGGCCGGTGGTGCCGATGCGGCCAACCTGCTGAAACCTGCACTGGCGCGTGGCGAACTGCGCACCAT
CGCCGCCACCTGGTCCGAATACAAACAGTATTTTGAACGCGATGCCGCACTGGAGCGCCGCTTCCAGATGGTCAAAGTGG
ACGAGCCGGATGATGACACCGCCTGCCTGATGCTGCGTGGCCTGAAAGAACGTTACGCCACCCATCACGGCGTGCATATT
CTGGACGCCGCTATCACCGCAGCGGTTACCCTGTCGCGCCGCTTTCTGACCGGTCGCCAACTGCCGGACAAAGCGGTGGA
TCTTCTCGACACCGCAGGTGCGCGCGTGCGCATGAGCATCGACACCTTGCCGACTGCGTTGATGGAGATTAACGCCGAAC
TGGCCGCACTGGCGATGGAGCAACAGGCCATCGAACAGGACTTGCTCCTGCTGCCGAATGTCAGTTCAACGCGCTTACCT
GAGATTGAGCAACGCCGCGCCGCGCTGGCGGTTGGGCAGCACACACTCGAACAGCAATATAAAGAAGAGAAGCGGTTGAC
CACCCTGATTATTGAGGCGCGTCAGGACATCGCCAACGCAGCACATCTGGTCGCGTTGCAGGAGGAACTCGTTCAGATTC
AGGGCAATGCGCCGCTGTTGTCGCTGGACGTTGATGTGCGCACTGTTGCGGCTGTGATCGCCGACTGGACCGGTGTGCCG
CTGGGCAGTTTACTCAAAGACGAACAAACCAACTTGCTGTCACTGGAAAATCGTCTGGGTGAGCGAGTGATTGGGCAGGA
TGCGGCATTAGGTGCGCTGGCGCAACGGCTGCGGGCCGCCAAAACCGGCCTGACATCAGAGAATGGCCCGCTGGGGGTGT
TCCTGCTGGTCGGGCCGAGTGGGATCGGCAAAACCGAAACCGCGTTGGCACTGGCCGACAGCCTGTTCGGCGGGGAAAAA
TCGCTGATCACCATCAACTTATCGGAGTATCAGGAAGCGCACACCGTCTCCCAGTTGAAAGGGTCGCCCCCGGGTTATGT
CGGTTACGGACAGGGCGGCGTATTAACCGAAGCGGTACGTAAACGGCCTTACAGCGTGGTGCTGCTGGATGAAGTGGAAA
AAGCCCATCGTGATGTGCTGAACCTGTTCTATCAGGTGTTTGACCGGGGGTTCATGCGCGACGGTGAAGGGCGCGAAATT
GATTTCCGCAACACGGTCATTGTGATGACCGCCAATCTGGGCAGTGATCATCTGATGCAGTTGCTGGATGAGCAACCGGA
CGCGCCGGACAGCACCCTGCATGAACTGCTGCGGCCGATCCTACGCGACCACTTCCAGCCCGCGCTGCTGGCCCGCTTCC
AGACCTTGATTTACCGCCCGCTTCAGGTGGATGCGCTCAAACGCATTGTGGCGATAAAACTGAATCAGGTGGCGCAACGC
CTGCACTGTCACTACGGCCTGAGCTGCCAGATTGAAGACAGCCTGACCGACACACTGGTCGCCGCCTGCCTGCTGCCGGA
CACCGGCGCACGCAACATCGACAGCCTGCTCAATCAGCAGATTTTACCGGTATTGAGCCAGCAGCTGTTAAGCCGCATGA
GCGAGCAACAGCGCACCACCTCGCTGACGCTGGGCTGGCATGAAGAAGATGGCATCACGCTGACATTTGAGGGCGAATAA

Upstream 100 bases:

>100_bases
ACCCTTTAATGACCTTATGGGCCTTGGTTTCCTTAGTAAAGGAAAGGCTACGGGCGGTAGCGTGTCCAAATAGGGTAAAT
GGCAAACAAGGAAGATCTTA

Downstream 100 bases:

>100_bases
AAATGAATACCTTTCTCCCGACTATTCGGTTTGACCATAGCCACCACAAACTGGTGGTCCGCGACAGCACCGCCGCCGTT
GATGTGCTGGGCTTTGAAGG

Product: heat shock protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 879; Mature: 878

Protein sequence:

>879_residues
MTTHSAHLLRRLNPYCAQALAGAATLCQTRAHAEITVEHWLLKLLEQGEGDITVIARRYEWDMDSLWQGLLSHLDTLPRT
VQGKPQLSAALQQLIKNAWLDASLQENADAVRSVHLMAALIATPSLLVAEAAWPLLSLSTTQLQRLLPLLDNQSDERPEV
QQAAALADSPVNLTDEAATVTSASGQPQLNDALQAALDKFTLDVTAKARANQIDPIFGRDSEIRQMIDILSRRRKNNPIL
VGEPGVGKTALVEGLALRIADGNVPDSLKTVSVRTLDLGLLQAGAGVKGEFEQRLKNVIEAVQQSPSPVLLFIDEAHTII
GAGNQAGGADAANLLKPALARGELRTIAATWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKERYATHHGVHI
LDAAITAAVTLSRRFLTGRQLPDKAVDLLDTAGARVRMSIDTLPTALMEINAELAALAMEQQAIEQDLLLLPNVSSTRLP
EIEQRRAALAVGQHTLEQQYKEEKRLTTLIIEARQDIANAAHLVALQEELVQIQGNAPLLSLDVDVRTVAAVIADWTGVP
LGSLLKDEQTNLLSLENRLGERVIGQDAALGALAQRLRAAKTGLTSENGPLGVFLLVGPSGIGKTETALALADSLFGGEK
SLITINLSEYQEAHTVSQLKGSPPGYVGYGQGGVLTEAVRKRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGREI
DFRNTVIVMTANLGSDHLMQLLDEQPDAPDSTLHELLRPILRDHFQPALLARFQTLIYRPLQVDALKRIVAIKLNQVAQR
LHCHYGLSCQIEDSLTDTLVAACLLPDTGARNIDSLLNQQILPVLSQQLLSRMSEQQRTTSLTLGWHEEDGITLTFEGE

Sequences:

>Translated_879_residues
MTTHSAHLLRRLNPYCAQALAGAATLCQTRAHAEITVEHWLLKLLEQGEGDITVIARRYEWDMDSLWQGLLSHLDTLPRT
VQGKPQLSAALQQLIKNAWLDASLQENADAVRSVHLMAALIATPSLLVAEAAWPLLSLSTTQLQRLLPLLDNQSDERPEV
QQAAALADSPVNLTDEAATVTSASGQPQLNDALQAALDKFTLDVTAKARANQIDPIFGRDSEIRQMIDILSRRRKNNPIL
VGEPGVGKTALVEGLALRIADGNVPDSLKTVSVRTLDLGLLQAGAGVKGEFEQRLKNVIEAVQQSPSPVLLFIDEAHTII
GAGNQAGGADAANLLKPALARGELRTIAATWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKERYATHHGVHI
LDAAITAAVTLSRRFLTGRQLPDKAVDLLDTAGARVRMSIDTLPTALMEINAELAALAMEQQAIEQDLLLLPNVSSTRLP
EIEQRRAALAVGQHTLEQQYKEEKRLTTLIIEARQDIANAAHLVALQEELVQIQGNAPLLSLDVDVRTVAAVIADWTGVP
LGSLLKDEQTNLLSLENRLGERVIGQDAALGALAQRLRAAKTGLTSENGPLGVFLLVGPSGIGKTETALALADSLFGGEK
SLITINLSEYQEAHTVSQLKGSPPGYVGYGQGGVLTEAVRKRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGREI
DFRNTVIVMTANLGSDHLMQLLDEQPDAPDSTLHELLRPILRDHFQPALLARFQTLIYRPLQVDALKRIVAIKLNQVAQR
LHCHYGLSCQIEDSLTDTLVAACLLPDTGARNIDSLLNQQILPVLSQQLLSRMSEQQRTTSLTLGWHEEDGITLTFEGE
>Mature_878_residues
TTHSAHLLRRLNPYCAQALAGAATLCQTRAHAEITVEHWLLKLLEQGEGDITVIARRYEWDMDSLWQGLLSHLDTLPRTV
QGKPQLSAALQQLIKNAWLDASLQENADAVRSVHLMAALIATPSLLVAEAAWPLLSLSTTQLQRLLPLLDNQSDERPEVQ
QAAALADSPVNLTDEAATVTSASGQPQLNDALQAALDKFTLDVTAKARANQIDPIFGRDSEIRQMIDILSRRRKNNPILV
GEPGVGKTALVEGLALRIADGNVPDSLKTVSVRTLDLGLLQAGAGVKGEFEQRLKNVIEAVQQSPSPVLLFIDEAHTIIG
AGNQAGGADAANLLKPALARGELRTIAATWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKERYATHHGVHIL
DAAITAAVTLSRRFLTGRQLPDKAVDLLDTAGARVRMSIDTLPTALMEINAELAALAMEQQAIEQDLLLLPNVSSTRLPE
IEQRRAALAVGQHTLEQQYKEEKRLTTLIIEARQDIANAAHLVALQEELVQIQGNAPLLSLDVDVRTVAAVIADWTGVPL
GSLLKDEQTNLLSLENRLGERVIGQDAALGALAQRLRAAKTGLTSENGPLGVFLLVGPSGIGKTETALALADSLFGGEKS
LITINLSEYQEAHTVSQLKGSPPGYVGYGQGGVLTEAVRKRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGREID
FRNTVIVMTANLGSDHLMQLLDEQPDAPDSTLHELLRPILRDHFQPALLARFQTLIYRPLQVDALKRIVAIKLNQVAQRL
HCHYGLSCQIEDSLTDTLVAACLLPDTGARNIDSLLNQQILPVLSQQLLSRMSEQQRTTSLTLGWHEEDGITLTFEGE

Specific function: Required for secretion of hcp1 probably by providing the energy source for its translocation [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=301, Percent_Identity=34.21926910299, Blast_Score=166, Evalue=9e-41,
Organism=Escherichia coli, GI1788943, Length=683, Percent_Identity=43.6310395314788, Blast_Score=546, Evalue=1e-156,
Organism=Escherichia coli, GI1787109, Length=270, Percent_Identity=44.4444444444444, Blast_Score=235, Evalue=8e-63,
Organism=Saccharomyces cerevisiae, GI6320464, Length=738, Percent_Identity=39.7018970189702, Blast_Score=464, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6323002, Length=707, Percent_Identity=37.3408769448373, Blast_Score=434, Evalue=1e-122,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR017729
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 96150; Mature: 96019

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00870 CLPAB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTHSAHLLRRLNPYCAQALAGAATLCQTRAHAEITVEHWLLKLLEQGEGDITVIARRYE
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCEEEEEEECC
WDMDSLWQGLLSHLDTLPRTVQGKPQLSAALQQLIKNAWLDASLQENADAVRSVHLMAAL
CCHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IATPSLLVAEAAWPLLSLSTTQLQRLLPLLDNQSDERPEVQQAAALADSPVNLTDEAATV
HHCCHHHHHHHHCHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHEE
TSASGQPQLNDALQAALDKFTLDVTAKARANQIDPIFGRDSEIRQMIDILSRRRKNNPIL
ECCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEE
VGEPGVGKTALVEGLALRIADGNVPDSLKTVSVRTLDLGLLQAGAGVKGEFEQRLKNVIE
EECCCCCHHHHHHHHEEEEECCCCCCCHHEEEEEEEHHHHHHCCCCCCHHHHHHHHHHHH
AVQQSPSPVLLFIDEAHTIIGAGNQAGGADAANLLKPALARGELRTIAATWSEYKQYFER
HHHCCCCCEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
DAALERRFQMVKVDEPDDDTACLMLRGLKERYATHHGVHILDAAITAAVTLSRRFLTGRQ
HHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
LPDKAVDLLDTAGARVRMSIDTLPTALMEINAELAALAMEQQAIEQDLLLLPNVSSTRLP
CCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCC
EIEQRRAALAVGQHTLEQQYKEEKRLTTLIIEARQDIANAAHLVALQEELVQIQGNAPLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
SLDVDVRTVAAVIADWTGVPLGSLLKDEQTNLLSLENRLGERVIGQDAALGALAQRLRAA
EECCHHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
KTGLTSENGPLGVFLLVGPSGIGKTETALALADSLFGGEKSLITINLSEYQEAHTVSQLK
HCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHC
GSPPGYVGYGQGGVLTEAVRKRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGREI
CCCCCEECCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
DFRNTVIVMTANLGSDHLMQLLDEQPDAPDSTLHELLRPILRDHFQPALLARFQTLIYRP
ECCCEEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
LQVDALKRIVAIKLNQVAQRLHCHYGLSCQIEDSLTDTLVAACLLPDTGARNIDSLLNQQ
CHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ILPVLSQQLLSRMSEQQRTTSLTLGWHEEDGITLTFEGE
HHHHHHHHHHHHHHHHHHHCEEEEEEECCCCEEEEECCC
>Mature Secondary Structure 
TTHSAHLLRRLNPYCAQALAGAATLCQTRAHAEITVEHWLLKLLEQGEGDITVIARRYE
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCEEEEEEECC
WDMDSLWQGLLSHLDTLPRTVQGKPQLSAALQQLIKNAWLDASLQENADAVRSVHLMAAL
CCHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IATPSLLVAEAAWPLLSLSTTQLQRLLPLLDNQSDERPEVQQAAALADSPVNLTDEAATV
HHCCHHHHHHHHCHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHEE
TSASGQPQLNDALQAALDKFTLDVTAKARANQIDPIFGRDSEIRQMIDILSRRRKNNPIL
ECCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEE
VGEPGVGKTALVEGLALRIADGNVPDSLKTVSVRTLDLGLLQAGAGVKGEFEQRLKNVIE
EECCCCCHHHHHHHHEEEEECCCCCCCHHEEEEEEEHHHHHHCCCCCCHHHHHHHHHHHH
AVQQSPSPVLLFIDEAHTIIGAGNQAGGADAANLLKPALARGELRTIAATWSEYKQYFER
HHHCCCCCEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
DAALERRFQMVKVDEPDDDTACLMLRGLKERYATHHGVHILDAAITAAVTLSRRFLTGRQ
HHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
LPDKAVDLLDTAGARVRMSIDTLPTALMEINAELAALAMEQQAIEQDLLLLPNVSSTRLP
CCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCC
EIEQRRAALAVGQHTLEQQYKEEKRLTTLIIEARQDIANAAHLVALQEELVQIQGNAPLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
SLDVDVRTVAAVIADWTGVPLGSLLKDEQTNLLSLENRLGERVIGQDAALGALAQRLRAA
EECCHHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
KTGLTSENGPLGVFLLVGPSGIGKTETALALADSLFGGEKSLITINLSEYQEAHTVSQLK
HCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHC
GSPPGYVGYGQGGVLTEAVRKRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGREI
CCCCCEECCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
DFRNTVIVMTANLGSDHLMQLLDEQPDAPDSTLHELLRPILRDHFQPALLARFQTLIYRP
ECCCEEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
LQVDALKRIVAIKLNQVAQRLHCHYGLSCQIEDSLTDTLVAACLLPDTGARNIDSLLNQQ
CHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ILPVLSQQLLSRMSEQQRTTSLTLGWHEEDGITLTFEGE
HHHHHHHHHHHHHHHHHHHCEEEEEEECCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]