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The map label for this gene is ychM [H]

Identifier: 22126170

GI number: 22126170

Start: 2521432

End: 2523129

Strand: Direct

Name: ychM [H]

Synonym: y2285

Alternate gene names: 22126170

Gene position: 2521432-2523129 (Clockwise)

Preceding gene: 22126169

Following gene: 22126177

Centisome position: 54.8

GC content: 51.94

Gene sequence:

>1698_bases
ATGAAAACGCACGGAATTAACGGCATTAGGCCGTTCAGCGCAATTATTGACGCTTGCTGGCGAGAAACTTATACACTTCA
ACGACTTTTCAAAGACATAATTGCCGGTGTCACCGTCGGTATTATTGCCATCCCGTTGGCTATGGCATTGGCGATTGCCA
GTGGTGTGCCACCGCAATACGGCTTGTATACTTCGGCTATCGCCGGGATCGTGATCGCGGTCAGCGGTGGTTCCCGCTAC
AGCGTATCCGGCCCTACCGCAGCCTTTGTGGTCATTTTGTATCCGGTGTCACAACAGTTTGGTCTAGCCGGCTTACTCTT
GGCGACAATATTATCCGGTCTATTTCTGCTCTGTATGGGGTTTGCCCGGCTTGGGCGGTTGATCGAATATATACCGTTAT
CAGTGACCCTCGGCTTCACTTCAGGAATTGCCATCACCATTGCAACCATGCAGGTGAAAGATTTCTTCGGGTTACACCTG
GTCGCCGTGCCAGAAAATTATGTTGGAAAAGTCACCGCCCTCGCACAGGCCATGCCAACGATTAATGTGAGTGATACGTT
AATTGCGACGGTTACCTTGCTGGTATTAATCCTTTGGCCACGGCTGAAACTAAAGTTACCGGGTCACTTACCTGCATTAG
TCGCGGGTACTGCAGTCATGGGGGTGCTCTCACTGTTTGATCAACAGGTTGCGACTATCGGCTCACGCTTTGGTTATCTC
TTGGCTGATGGGACTCAGGGCCAAGGTATTCCGCCTATTCTGCCGCAGTTTGTGCTGCCCTGGCAGTTACCTGCCGCAAA
TGGTCAAGAGTTTGTGCTGAACTGGGCGACACTTTCTGCACTGCTGCCCGCCGCCTTTTCAATGGCGATGTTAGGGGCGA
TAGAGTCCTTGCTGTGCGCAGTCGTCCTTGATGGTATGACTGGGCAGAAGCATCATTCAAACAGTGAATTGGTCGGTCAA
GGGCTAGGCAACATTGTCGCCCCCTTCTTTGGTGGGATTACCGCAACGGCAGCCATCGCCCGTTCTGCTGCTAACGTCCG
CGCGGGTGCCACCTCGCCGGTATCCGCGATTATCCACGCGGTGCTGGTGCTACTGGCGTTACTGGTACTGGCACCGATGC
TGTCGTACCTGCCATTAGCCGCAATGGCTTCCCTGCTGTTGATTGTCGCCTGGAACATGAGTGAAGCCCATAAGGTTATT
GACCTGCTGCGCCGTGCGCCTAAGGACGACATCATCATTATGCTGCTGTGTATGAGCCTCACCGTATTGTTCGACATGGT
GATCGCGATAACGGTTGGGATTGTGTTGGCATCATTGTTGTTTATGCGACGTATTGCGCAAATGACACGCCTGAGTGAGA
TACCTGCGGCGGTTAATGATAAGACATTGGTATTGCGAGTAAACGGCCCGTTGTTCTTCGATGCCGCTGAACGGATATTC
AGTGAGTTGCTCACCCGTTGCGATAATTATGACACTATTATCCTGCAATGGGATGCTGTGCCCGTTCTCGATGCCGGTGG
CTTGAATGCTTTCCTGCGCTTTACTGAAGCGTTGACAGAGCAGCAACTGCTGGTTATCACAGATATTCCTTTCCAGCCAC
TGAAGACGCTGGCCAGAGCCAGGGTGAAGCCAATTTCAGGCAAGTTGAATTTCTATGCTTCTTTACCGGAAGCACTGGCG
GCACTACAGAATAACTAG

Upstream 100 bases:

>100_bases
TCATTGTTAAATTGGCGTATCGTTGTTATATGCTACTCGAGACGGACCTCTATTGGCCCGCCATTTATTTTGTCTTTTCC
TTATTTGGTTTGAACCTTAG

Downstream 100 bases:

>100_bases
GTGTTTTGATTATCAAAAAAGGCAGCTTAGTTACCTACGCTGCGTGAGGTTATTGACAAAGTGCCCGCGACGGAGAGAAC
AGGCAGATCGTAAAGACGCC

Product: putative sulfate transporter YchM

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MKTHGINGIRPFSAIIDACWRETYTLQRLFKDIIAGVTVGIIAIPLAMALAIASGVPPQYGLYTSAIAGIVIAVSGGSRY
SVSGPTAAFVVILYPVSQQFGLAGLLLATILSGLFLLCMGFARLGRLIEYIPLSVTLGFTSGIAITIATMQVKDFFGLHL
VAVPENYVGKVTALAQAMPTINVSDTLIATVTLLVLILWPRLKLKLPGHLPALVAGTAVMGVLSLFDQQVATIGSRFGYL
LADGTQGQGIPPILPQFVLPWQLPAANGQEFVLNWATLSALLPAAFSMAMLGAIESLLCAVVLDGMTGQKHHSNSELVGQ
GLGNIVAPFFGGITATAAIARSAANVRAGATSPVSAIIHAVLVLLALLVLAPMLSYLPLAAMASLLLIVAWNMSEAHKVI
DLLRRAPKDDIIIMLLCMSLTVLFDMVIAITVGIVLASLLFMRRIAQMTRLSEIPAAVNDKTLVLRVNGPLFFDAAERIF
SELLTRCDNYDTIILQWDAVPVLDAGGLNAFLRFTEALTEQQLLVITDIPFQPLKTLARARVKPISGKLNFYASLPEALA
ALQNN

Sequences:

>Translated_565_residues
MKTHGINGIRPFSAIIDACWRETYTLQRLFKDIIAGVTVGIIAIPLAMALAIASGVPPQYGLYTSAIAGIVIAVSGGSRY
SVSGPTAAFVVILYPVSQQFGLAGLLLATILSGLFLLCMGFARLGRLIEYIPLSVTLGFTSGIAITIATMQVKDFFGLHL
VAVPENYVGKVTALAQAMPTINVSDTLIATVTLLVLILWPRLKLKLPGHLPALVAGTAVMGVLSLFDQQVATIGSRFGYL
LADGTQGQGIPPILPQFVLPWQLPAANGQEFVLNWATLSALLPAAFSMAMLGAIESLLCAVVLDGMTGQKHHSNSELVGQ
GLGNIVAPFFGGITATAAIARSAANVRAGATSPVSAIIHAVLVLLALLVLAPMLSYLPLAAMASLLLIVAWNMSEAHKVI
DLLRRAPKDDIIIMLLCMSLTVLFDMVIAITVGIVLASLLFMRRIAQMTRLSEIPAAVNDKTLVLRVNGPLFFDAAERIF
SELLTRCDNYDTIILQWDAVPVLDAGGLNAFLRFTEALTEQQLLVITDIPFQPLKTLARARVKPISGKLNFYASLPEALA
ALQNN
>Mature_565_residues
MKTHGINGIRPFSAIIDACWRETYTLQRLFKDIIAGVTVGIIAIPLAMALAIASGVPPQYGLYTSAIAGIVIAVSGGSRY
SVSGPTAAFVVILYPVSQQFGLAGLLLATILSGLFLLCMGFARLGRLIEYIPLSVTLGFTSGIAITIATMQVKDFFGLHL
VAVPENYVGKVTALAQAMPTINVSDTLIATVTLLVLILWPRLKLKLPGHLPALVAGTAVMGVLSLFDQQVATIGSRFGYL
LADGTQGQGIPPILPQFVLPWQLPAANGQEFVLNWATLSALLPAAFSMAMLGAIESLLCAVVLDGMTGQKHHSNSELVGQ
GLGNIVAPFFGGITATAAIARSAANVRAGATSPVSAIIHAVLVLLALLVLAPMLSYLPLAAMASLLLIVAWNMSEAHKVI
DLLRRAPKDDIIIMLLCMSLTVLFDMVIAITVGIVLASLLFMRRIAQMTRLSEIPAAVNDKTLVLRVNGPLFFDAAERIF
SELLTRCDNYDTIILQWDAVPVLDAGGLNAFLRFTEALTEQQLLVITDIPFQPLKTLARARVKPISGKLNFYASLPEALA
ALQNN

Specific function: Possible sulfate transporter [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI262206105, Length=489, Percent_Identity=28.6298568507157, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI262206075, Length=489, Percent_Identity=28.6298568507157, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI262206069, Length=489, Percent_Identity=28.6298568507157, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI262206063, Length=489, Percent_Identity=28.6298568507157, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI4557535, Length=472, Percent_Identity=24.5762711864407, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI94721259, Length=495, Percent_Identity=23.8383838383838, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI94721257, Length=495, Percent_Identity=23.8383838383838, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI94721253, Length=495, Percent_Identity=23.8383838383838, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI94721255, Length=495, Percent_Identity=23.8383838383838, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI20336282, Length=510, Percent_Identity=22.5490196078431, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI16306483, Length=510, Percent_Identity=22.5490196078431, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI4505697, Length=440, Percent_Identity=24.7727272727273, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI39752683, Length=527, Percent_Identity=20.6831119544592, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI45827800, Length=527, Percent_Identity=20.1138519924099, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI45827802, Length=475, Percent_Identity=20.8421052631579, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI269784651, Length=455, Percent_Identity=21.978021978022, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI100913030, Length=543, Percent_Identity=23.7569060773481, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI47131207, Length=520, Percent_Identity=24.6153846153846, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI20336272, Length=520, Percent_Identity=24.6153846153846, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI87081859, Length=554, Percent_Identity=71.1191335740072, Blast_Score=735, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17551690, Length=620, Percent_Identity=20.9677419354839, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193203292, Length=533, Percent_Identity=21.3883677298311, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI86564196, Length=561, Percent_Identity=22.8163992869875, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17566848, Length=166, Percent_Identity=31.3253012048193, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562578, Length=441, Percent_Identity=23.8095238095238, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323121, Length=495, Percent_Identity=23.030303030303, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6325260, Length=434, Percent_Identity=25.1152073732719, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319771, Length=193, Percent_Identity=28.4974093264249, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI85815873, Length=432, Percent_Identity=28.4722222222222, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI19922482, Length=427, Percent_Identity=26.2295081967213, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24663084, Length=489, Percent_Identity=28.2208588957055, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21357695, Length=489, Percent_Identity=28.2208588957055, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24651449, Length=450, Percent_Identity=25.7777777777778, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24649801, Length=440, Percent_Identity=25.6818181818182, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI21358633, Length=529, Percent_Identity=25.7088846880907, Blast_Score=112, Evalue=9e-25,
Organism=Drosophila melanogaster, GI21358229, Length=485, Percent_Identity=26.5979381443299, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI21355087, Length=146, Percent_Identity=34.2465753424658, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647160, Length=146, Percent_Identity=34.2465753424658, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24666186, Length=296, Percent_Identity=26.0135135135135, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018045
- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 60114; Mature: 60114

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS50801 STAS ; PS01130 SLC26A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTHGINGIRPFSAIIDACWRETYTLQRLFKDIIAGVTVGIIAIPLAMALAIASGVPPQY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GLYTSAIAGIVIAVSGGSRYSVSGPTAAFVVILYPVSQQFGLAGLLLATILSGLFLLCMG
CHHHHHHHCEEEEECCCCEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
FARLGRLIEYIPLSVTLGFTSGIAITIATMQVKDFFGLHLVAVPENYVGKVTALAQAMPT
HHHHHHHHHHHHHEEEECCCCCEEEEEEEEEHHHHHCEEEEECCCHHHHHHHHHHHHCCC
INVSDTLIATVTLLVLILWPRLKLKLPGHLPALVAGTAVMGVLSLFDQQVATIGSRFGYL
CCCCHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
LADGTQGQGIPPILPQFVLPWQLPAANGQEFVLNWATLSALLPAAFSMAMLGAIESLLCA
EECCCCCCCCCCCCHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVLDGMTGQKHHSNSELVGQGLGNIVAPFFGGITATAAIARSAANVRAGATSPVSAIIHA
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VLVLLALLVLAPMLSYLPLAAMASLLLIVAWNMSEAHKVIDLLRRAPKDDIIIMLLCMSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
TVLFDMVIAITVGIVLASLLFMRRIAQMTRLSEIPAAVNDKTLVLRVNGPLFFDAAERIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEHHHHHHHH
SELLTRCDNYDTIILQWDAVPVLDAGGLNAFLRFTEALTEQQLLVITDIPFQPLKTLARA
HHHHHHCCCCCEEEEEECCCCEECCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHH
RVKPISGKLNFYASLPEALAALQNN
HCCCCCCCCCEEHHHHHHHHHHCCC
>Mature Secondary Structure
MKTHGINGIRPFSAIIDACWRETYTLQRLFKDIIAGVTVGIIAIPLAMALAIASGVPPQY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GLYTSAIAGIVIAVSGGSRYSVSGPTAAFVVILYPVSQQFGLAGLLLATILSGLFLLCMG
CHHHHHHHCEEEEECCCCEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
FARLGRLIEYIPLSVTLGFTSGIAITIATMQVKDFFGLHLVAVPENYVGKVTALAQAMPT
HHHHHHHHHHHHHEEEECCCCCEEEEEEEEEHHHHHCEEEEECCCHHHHHHHHHHHHCCC
INVSDTLIATVTLLVLILWPRLKLKLPGHLPALVAGTAVMGVLSLFDQQVATIGSRFGYL
CCCCHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
LADGTQGQGIPPILPQFVLPWQLPAANGQEFVLNWATLSALLPAAFSMAMLGAIESLLCA
EECCCCCCCCCCCCHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVLDGMTGQKHHSNSELVGQGLGNIVAPFFGGITATAAIARSAANVRAGATSPVSAIIHA
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VLVLLALLVLAPMLSYLPLAAMASLLLIVAWNMSEAHKVIDLLRRAPKDDIIIMLLCMSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
TVLFDMVIAITVGIVLASLLFMRRIAQMTRLSEIPAAVNDKTLVLRVNGPLFFDAAERIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEHHHHHHHH
SELLTRCDNYDTIILQWDAVPVLDAGGLNAFLRFTEALTEQQLLVITDIPFQPLKTLARA
HHHHHHCCCCCEEEEEECCCCEECCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHH
RVKPISGKLNFYASLPEALAALQNN
HCCCCCCCCCEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]