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The map label for this gene is nagZ [H]

Identifier: 22125668

GI number: 22125668

Start: 1954756

End: 1955793

Strand: Direct

Name: nagZ [H]

Synonym: y1775

Alternate gene names: 22125668

Gene position: 1954756-1955793 (Clockwise)

Preceding gene: 22125667

Following gene: 22125670

Centisome position: 42.49

GC content: 52.22

Gene sequence:

>1038_bases
GTGACCGTGGGTCCCGTGATGTTAGATGTTGCCAGCTATGAGCTGGATGCTGAAGAGCGTGAGATTTTAAAACACCCACT
GGTGGGAGGGTTGATCTTATTCAGCCGTAATTTTCATGATGCGGAGCAGTTACGCGAATTAGTACGCCAAATCCGTGCAG
CATCGCATGAACGTTTGGTGGTCGCAGTGGATCAGGAAGGGGGGCGGGTCCAACGCTTTCGTGACGGTTTTACCCGCCTG
CCAGCGGCTCAGTATTTCGCGGCTATCAATGATGCCGCTACTGCGGCTCAACTGGCGCAAGAGGCGGGGTGGTTGATGGC
AGCAGAAATGATGGCGATGGATATCGATATCAGTTTTGCTCCAGTACTGGATATTGGCCATGTCAGCGCCGCAATTGGTG
AGCGTTCATTCCACAGTGATCCACAACAGGCGCGGATAATGGCGGAGTGTTTCATCCGTGGGATGCACAGTGCAGGGATG
AAAACCACGGGCAAGCATTTTCCAGGGCACGGCGCAGTAACCGCAGATTCACATAAAGAGACGCCACATGATAATCGGCC
ACTGGCAGAAATCCGTACTCATGATATGGTTATATTTCGTGAATTGATCCAGCGGAAATTACTGGATGCGATTATGCCTG
CTCACGTGATTTATACCGAAGCCGATGCACGGCCTGCCAGCGGTTCTGCCTATTGGTTACAAGAGATATTGCGCCAAGAG
CTAGGGTTCGAGGGCATCATTTTCTCTGATGATCTCTCGATGGAAGGGGCTGCGATCATGGGCAGTTACGCCGAGCGCGG
CCAGGCATCGTTGGATGCCGGTTGCGATATGATTTTGGTGTGTAATAACCGTCAGGGGGCCGTGAGTGTGCTGGATAATC
TGTCTCCGATCAAAGCCGACCAACTGACCCGTTTGTACCATTCAGGGCAATTTGACCGCCAGACATTGATGGCTTCATCC
CGTTGGCAACAGGCGAATAAAGCATTAACGGCACTCAGCGAACGTTGGGATGCACATAAACAAACGTTGGGGCAATAG

Upstream 100 bases:

>100_bases
GCGCCGTTGCGCCAACGTTTTAATTTGTCTTTTTAAGCCCTGCGGCACCAAGCCCGCCGCTTCAAGCACGAAGGGTCGTT
ATCAATCTGAATAAAGTGAG

Downstream 100 bases:

>100_bases
GAGTAGCGCCGGGTACGCTTCGGTATTATTACTCGCCTCATAAGGGCCAAGAGCTCCCTCTTTTCTGTGGGGGCTTTGAT
CAGTAACGCACACTGCCGCG

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MTVGPVMLDVASYELDAEEREILKHPLVGGLILFSRNFHDAEQLRELVRQIRAASHERLVVAVDQEGGRVQRFRDGFTRL
PAAQYFAAINDAATAAQLAQEAGWLMAAEMMAMDIDISFAPVLDIGHVSAAIGERSFHSDPQQARIMAECFIRGMHSAGM
KTTGKHFPGHGAVTADSHKETPHDNRPLAEIRTHDMVIFRELIQRKLLDAIMPAHVIYTEADARPASGSAYWLQEILRQE
LGFEGIIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRQGAVSVLDNLSPIKADQLTRLYHSGQFDRQTLMASS
RWQQANKALTALSERWDAHKQTLGQ

Sequences:

>Translated_345_residues
MTVGPVMLDVASYELDAEEREILKHPLVGGLILFSRNFHDAEQLRELVRQIRAASHERLVVAVDQEGGRVQRFRDGFTRL
PAAQYFAAINDAATAAQLAQEAGWLMAAEMMAMDIDISFAPVLDIGHVSAAIGERSFHSDPQQARIMAECFIRGMHSAGM
KTTGKHFPGHGAVTADSHKETPHDNRPLAEIRTHDMVIFRELIQRKLLDAIMPAHVIYTEADARPASGSAYWLQEILRQE
LGFEGIIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRQGAVSVLDNLSPIKADQLTRLYHSGQFDRQTLMASS
RWQQANKALTALSERWDAHKQTLGQ
>Mature_344_residues
TVGPVMLDVASYELDAEEREILKHPLVGGLILFSRNFHDAEQLRELVRQIRAASHERLVVAVDQEGGRVQRFRDGFTRLP
AAQYFAAINDAATAAQLAQEAGWLMAAEMMAMDIDISFAPVLDIGHVSAAIGERSFHSDPQQARIMAECFIRGMHSAGMK
TTGKHFPGHGAVTADSHKETPHDNRPLAEIRTHDMVIFRELIQRKLLDAIMPAHVIYTEADARPASGSAYWLQEILRQEL
GFEGIIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRQGAVSVLDNLSPIKADQLTRLYHSGQFDRQTLMASSR
WQQANKALTALSERWDAHKQTLGQ

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides [H]

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787350, Length=338, Percent_Identity=76.3313609467456, Blast_Score=541, Evalue=1e-155,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022956
- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853 [H]

Pfam domain/function: PF00933 Glyco_hydro_3 [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 38180; Mature: 38049

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00775 GLYCOSYL_HYDROL_F3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVGPVMLDVASYELDAEEREILKHPLVGGLILFSRNFHDAEQLRELVRQIRAASHERLV
CCCCHHHHHHHHCCCCHHHHHHHHCCCHHHHEEEECCCCCHHHHHHHHHHHHHCCCCEEE
VAVDQEGGRVQRFRDGFTRLPAAQYFAAINDAATAAQLAQEAGWLMAAEMMAMDIDISFA
EEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCC
PVLDIGHVSAAIGERSFHSDPQQARIMAECFIRGMHSAGMKTTGKHFPGHGAVTADSHKE
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCC
TPHDNRPLAEIRTHDMVIFRELIQRKLLDAIMPAHVIYTEADARPASGSAYWLQEILRQE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCCHHHHHHHHHHH
LGFEGIIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRQGAVSVLDNLSPIKAD
CCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHCCCCCCHH
QLTRLYHSGQFDRQTLMASSRWQQANKALTALSERWDAHKQTLGQ
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVGPVMLDVASYELDAEEREILKHPLVGGLILFSRNFHDAEQLRELVRQIRAASHERLV
CCCHHHHHHHHCCCCHHHHHHHHCCCHHHHEEEECCCCCHHHHHHHHHHHHHCCCCEEE
VAVDQEGGRVQRFRDGFTRLPAAQYFAAINDAATAAQLAQEAGWLMAAEMMAMDIDISFA
EEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCC
PVLDIGHVSAAIGERSFHSDPQQARIMAECFIRGMHSAGMKTTGKHFPGHGAVTADSHKE
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCC
TPHDNRPLAEIRTHDMVIFRELIQRKLLDAIMPAHVIYTEADARPASGSAYWLQEILRQE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCCHHHHHHHHHHH
LGFEGIIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRQGAVSVLDNLSPIKAD
CCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHCCCCCCHH
QLTRLYHSGQFDRQTLMASSRWQQANKALTALSERWDAHKQTLGQ
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA