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The map label for this gene is dapB

Identifier: 221232268

GI number: 221232268

Start: 1481177

End: 1481944

Strand: Reverse

Name: dapB

Synonym: SPN23F_15220

Alternate gene names: 221232268

Gene position: 1481944-1481177 (Counterclockwise)

Preceding gene: 221232269

Following gene: 221232267

Centisome position: 66.71

GC content: 45.83

Gene sequence:

>768_bases
ATGAGTATTCGAGTAATTATTGCCGGTTTTAAGGGAAAGATGGGCCAGGCTGCTTGTCAGATGGTATTGACTGATCCAGA
CTTGGACTTGGTGGCAGTTTTGGATCCTTTTGAGTCTGAGTCAGAATGGCAGGGTATTCCTGTTTTCAAGGATAAGGCTG
ATTTAGCTGGTTTTGAAGCGGATGTCTGGGTAGATTTTACTACTCCAGCTGTTGCCTACGAAAATACACGTTTTGCTCTT
GAAAATGGCTTTGCTCCAGTAGTTGGAACGACTGGTTTCACGAGTGAAGAAATTGCAGAGCTAAAAGAATTTTCTCGTGC
CCAAGACTTGGGTGGCCTGATTGCCCCTAACTTTGCCTTGGGTGCTGTCTTACTCATGCAATTTGCGACGCAGGCTGCCA
AATATTTCCCAAATGTGGAGATTATTGAGCTCCATCATGACAAGAAAAAGGATGCTCCGAGTGGAACAGCCATTAAAACA
GCTGAGTTGATGGCAGAGGTTCGAGAGTCCATTCAGCAAGGTGCAGCAGATGAGGAAGAGCTGATTGCTGGTGCTCGTGG
TGCTGACTTTGATGGTATGCGCATCCACTCAGTTCGTTTGCCAGGCTTGGTAGCTCATCAGGAAGTCATCTTTGGCAATC
AGGGAGAAGGGTTGACCCTCCGTCATGACTCCTATGATCGCATCTCCTTCATGACAGGAGTCAATTTGGGAATTAAAGAA
GTTGTCAAGCGTCATGAGCTTGTCTATGGATTAGAACACTTATTATGA

Upstream 100 bases:

>100_bases
GTGAAAAAGATAGTTCTTCCAAGAAGTAGACACTTCTTGATTGGAATTCCTATTTTCACTTTGTGTTCTTACGGACTTTG
TATCTTAGACAGGAGTAGAG

Downstream 100 bases:

>100_bases
GATTAATGCAAATGCCTTCTGAATTTCAGAAGGCTTTACCAGTATTAGAAAAAATTAAAGAAGCAGGCTTTGAGGCTTAT
TTTGTTGGGGGCTCTGTTCG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQGIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFAL
ENGFAPVVGTTGFTSEEIAELKEFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGLTLRHDSYDRISFMTGVNLGIKE
VVKRHELVYGLEHLL

Sequences:

>Translated_255_residues
MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQGIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFAL
ENGFAPVVGTTGFTSEEIAELKEFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGLTLRHDSYDRISFMTGVNLGIKE
VVKRHELVYGLEHLL
>Mature_254_residues
SIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQGIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALE
NGFAPVVGTTGFTSEEIAELKEFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKTA
ELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGLTLRHDSYDRISFMTGVNLGIKEV
VKRHELVYGLEHLL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=253, Percent_Identity=30.0395256916996, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_STRP2 (Q04JJ1)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_816847.1
- ProteinModelPortal:   Q04JJ1
- SMR:   Q04JJ1
- STRING:   Q04JJ1
- EnsemblBacteria:   EBSTRT00000019313
- GeneID:   4442704
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1387
- eggNOG:   COG0289
- GeneTree:   EBGT00050000029374
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27837; Mature: 27706

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQGIPVFKDKADLAGFEA
CEEEEEEECCCCCCCHHHEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCE
DVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELKEFSRAQDLGGLIAPNFAL
EEEEEECCCEEEECCCEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHH
GAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKTAELMAEVRESIQQGAADEEE
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHH
LIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGLTLRHDSYDRISFMTGVNLGIKE
HHHCCCCCCCCCEEEEEEECCCEEECHHEEECCCCCCEEEECCCCCCEEEECCCCCCHHH
VVKRHELVYGLEHLL
HHHHHHHHHHHHHHC
>Mature Secondary Structure 
SIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQGIPVFKDKADLAGFEA
EEEEEEECCCCCCCHHHEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCE
DVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELKEFSRAQDLGGLIAPNFAL
EEEEEECCCEEEECCCEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHH
GAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKTAELMAEVRESIQQGAADEEE
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHH
LIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGLTLRHDSYDRISFMTGVNLGIKE
HHHCCCCCCCCCEEEEEEECCCEEECHHEEECCCCCCEEEECCCCCCEEEECCCCCCHHH
VVKRHELVYGLEHLL
HHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA