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The map label for this gene is fadE5 [C]

Identifier: 221230853

GI number: 221230853

Start: 3055097

End: 3056932

Strand: Direct

Name: fadE5 [C]

Synonym: MLBr_02563

Alternate gene names: 221230853

Gene position: 3055097-3056932 (Clockwise)

Preceding gene: 221230852

Following gene: 221230855

Centisome position: 93.48

GC content: 60.4

Gene sequence:

>1836_bases
GTGAGTCACTACAAAAGCAACGTTCGCGACCAGGTTTTTAACCTCTTTGAGGTGTTGGGCGTGGACAAGGCTTTCGGTAC
AGACGAGTTCAGCAATCTGGACGCCGACACCGCCTACGAAATGTTGACCGAGGTCAGCCGTCTGGCCGAGGGACCCGTCG
CCGCGTCGTTCGCTGAAGGCGACCGCAACCCACCAGTATTCCACCCCGAAACTCACTCGATCACACTGCCGGAGTCGTTC
AAGAAATCCTGCAGGGCGGTGGCCGAAGCCGGTTGGAGCAAGGCCGGCATCGACGAGGCACTCGGTGGCACGCCGATGCC
CAAGGCGCTGTTATGGGCACTGCACGAGCATCTGATGGGCGCCAACCCGGCGGTGTGGATTTATGCTGGCGGTGCCGGCT
TCGCTAACATCCTCTACCACCTCGGCACCGAGAAACAGAAGAAGTGGGCGGTGTGGGCTGCCGAGCGCAATTGGGGTTCG
ACCATGGTGCTCACCGAGCCAGATGCCGGTTCGGATGTGGGTGCCGGCCGGACCAAGGCCGTTCATCAGGAAGACGATTC
CTGGCACATTGATGGGGTCAAGCGATTCATCACCTCGGGTGACTCCGACGACCTATTCGAGAACATCTTCCACCTCGTGC
TGGCCCGCCCCGAGGGCGCCGGGCCTGGCACCAAGGGGCTGTCACTATTCTTCGTGCCCAAGTTCCTGTTCGACTTCGAA
ACCGGTGAGCTCGGCGAACGCAACGGGGTCTTCGTCACCAACGTCGAGCACAAGATGGGCCTCAAGGTGTCTGCCACTTG
TGAGCTGTCCTTTGGCCAGCACGGCGTGCCCGCTAAGGGCTGGCTGGTCGGCGATGTGCACGATGGCATAGCGCAGATGT
TTGAGGTCATCGAGCAGGCACGCATGATGGTCGGCACCAAGGCGATTGCTACCCTGTCGACCGGCTATCTGAACGCGCTG
GAATACGCAAAGTCCCGCGTGCAGGGCGCCGACCTGACCCAAATGACCGACAAGACCGCACCGCGGGTAACCATCACGCA
TCACCCTGATGTGCGCCGGTCGCTAATGACTCAAAAGGCCTACGCCGAAGGTCTGCGAGCGCTGTACCTCTACACAGCCA
CGTTCCAGGATGCAGCAGTGGCCGAAGCGGTGCACGGCGTGGACGCCAAGCTGGCGGTCAAGATCAACGACCTGATGCTG
CCGTTAGTCAAAGGGGTGGGCTCCGAGCAGGCCTACGCGAAACTCACTGAGAGCCTGCAGACCCTCGGTGGTTCGGGCTT
CCTCCAAGACTACCCGATTGAGCAATACATCCGCGACGCGAAAATTGACTCGCTGTACGAAGGCACCACCGCCATCCAGG
CGCAGGACTTTTTCTTCCGCAAGATCGTCCGCGACAAGGGCGTGGCACTGTCCTATGTGTCGGGACAAATCCAGCAATTC
GTCGACAGCGAGACTGGTAACGGTCGGCTGAAAAGCGAACGCGAACTGCTGGCCAAGGCCCTAACCGACATCCAGGGGAT
GGAAGCCTCACTGACCGGCTATCTGATGGCAGCTCAGCAAGACGTCACCAGCTTGTACAAGGTGGGTCTGGGGTCGGTGC
GCTTCCTAATGAGCGTCGGTGACCTGATCATCGGCTGGTTGCTGCAGCGCCAGGCCGCGGTGGCGGTGCAGGCACTCGAT
GCCGGCGCTAGCAGCGCTGAGCGTTCCTTCTACGAAGGCAAAGTCGCGGTGTCGTCATTCTTCGCGAAAAACTTCTTGCC
ACTGTTGACCAGCACTCGCGAAGTGCTTGAGGTGCTGGACAACGACATCATGGAGCTTGACGAAGCCGCCTTCTAG

Upstream 100 bases:

>100_bases
ACTATATTGACTGATAATATATTTTATTCGGTGTTACTGGTGGGTAACTTAGTCCGAAGTACCCAACCTCTTGATGGTTT
TCTCGACTAGGAGGACCGTA

Downstream 100 bases:

>100_bases
TAGTCGATGACAAGCGGAACTGCAAGGTCCCCCGCTTCAACGTTGAAGCGGGGGACCTTAAGTCCGGTAGTCGCTAAATA
TTAATCCAGTAGTTACCGTA

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; BCAD; SCAD [H]

Number of amino acids: Translated: 611; Mature: 610

Protein sequence:

>611_residues
MSHYKSNVRDQVFNLFEVLGVDKAFGTDEFSNLDADTAYEMLTEVSRLAEGPVAASFAEGDRNPPVFHPETHSITLPESF
KKSCRAVAEAGWSKAGIDEALGGTPMPKALLWALHEHLMGANPAVWIYAGGAGFANILYHLGTEKQKKWAVWAAERNWGS
TMVLTEPDAGSDVGAGRTKAVHQEDDSWHIDGVKRFITSGDSDDLFENIFHLVLARPEGAGPGTKGLSLFFVPKFLFDFE
TGELGERNGVFVTNVEHKMGLKVSATCELSFGQHGVPAKGWLVGDVHDGIAQMFEVIEQARMMVGTKAIATLSTGYLNAL
EYAKSRVQGADLTQMTDKTAPRVTITHHPDVRRSLMTQKAYAEGLRALYLYTATFQDAAVAEAVHGVDAKLAVKINDLML
PLVKGVGSEQAYAKLTESLQTLGGSGFLQDYPIEQYIRDAKIDSLYEGTTAIQAQDFFFRKIVRDKGVALSYVSGQIQQF
VDSETGNGRLKSERELLAKALTDIQGMEASLTGYLMAAQQDVTSLYKVGLGSVRFLMSVGDLIIGWLLQRQAAVAVQALD
AGASSAERSFYEGKVAVSSFFAKNFLPLLTSTREVLEVLDNDIMELDEAAF

Sequences:

>Translated_611_residues
MSHYKSNVRDQVFNLFEVLGVDKAFGTDEFSNLDADTAYEMLTEVSRLAEGPVAASFAEGDRNPPVFHPETHSITLPESF
KKSCRAVAEAGWSKAGIDEALGGTPMPKALLWALHEHLMGANPAVWIYAGGAGFANILYHLGTEKQKKWAVWAAERNWGS
TMVLTEPDAGSDVGAGRTKAVHQEDDSWHIDGVKRFITSGDSDDLFENIFHLVLARPEGAGPGTKGLSLFFVPKFLFDFE
TGELGERNGVFVTNVEHKMGLKVSATCELSFGQHGVPAKGWLVGDVHDGIAQMFEVIEQARMMVGTKAIATLSTGYLNAL
EYAKSRVQGADLTQMTDKTAPRVTITHHPDVRRSLMTQKAYAEGLRALYLYTATFQDAAVAEAVHGVDAKLAVKINDLML
PLVKGVGSEQAYAKLTESLQTLGGSGFLQDYPIEQYIRDAKIDSLYEGTTAIQAQDFFFRKIVRDKGVALSYVSGQIQQF
VDSETGNGRLKSERELLAKALTDIQGMEASLTGYLMAAQQDVTSLYKVGLGSVRFLMSVGDLIIGWLLQRQAAVAVQALD
AGASSAERSFYEGKVAVSSFFAKNFLPLLTSTREVLEVLDNDIMELDEAAF
>Mature_610_residues
SHYKSNVRDQVFNLFEVLGVDKAFGTDEFSNLDADTAYEMLTEVSRLAEGPVAASFAEGDRNPPVFHPETHSITLPESFK
KSCRAVAEAGWSKAGIDEALGGTPMPKALLWALHEHLMGANPAVWIYAGGAGFANILYHLGTEKQKKWAVWAAERNWGST
MVLTEPDAGSDVGAGRTKAVHQEDDSWHIDGVKRFITSGDSDDLFENIFHLVLARPEGAGPGTKGLSLFFVPKFLFDFET
GELGERNGVFVTNVEHKMGLKVSATCELSFGQHGVPAKGWLVGDVHDGIAQMFEVIEQARMMVGTKAIATLSTGYLNALE
YAKSRVQGADLTQMTDKTAPRVTITHHPDVRRSLMTQKAYAEGLRALYLYTATFQDAAVAEAVHGVDAKLAVKINDLMLP
LVKGVGSEQAYAKLTESLQTLGGSGFLQDYPIEQYIRDAKIDSLYEGTTAIQAQDFFFRKIVRDKGVALSYVSGQIQQFV
DSETGNGRLKSERELLAKALTDIQGMEASLTGYLMAAQQDVTSLYKVGLGSVRFLMSVGDLIIGWLLQRQAAVAVQALDA
GASSAERSFYEGKVAVSSFFAKNFLPLLTSTREVLEVLDNDIMELDEAAF

Specific function: Has an optimum specificity for 4-carbon length fatty acyl-CoAs [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=316, Percent_Identity=28.4810126582279, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI4557233, Length=318, Percent_Identity=27.6729559748428, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI4557231, Length=310, Percent_Identity=27.4193548387097, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI187960098, Length=310, Percent_Identity=27.4193548387097, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI4501857, Length=393, Percent_Identity=24.9363867684478, Blast_Score=84, Evalue=5e-16,
Organism=Escherichia coli, GI87082384, Length=326, Percent_Identity=28.8343558282209, Blast_Score=96, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI86563383, Length=383, Percent_Identity=26.1096605744125, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI86563381, Length=383, Percent_Identity=26.1096605744125, Blast_Score=83, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17569725, Length=318, Percent_Identity=29.874213836478, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17534899, Length=316, Percent_Identity=29.746835443038, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=367, Percent_Identity=24.7956403269755, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24666513, Length=392, Percent_Identity=25.5102040816327, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24660351, Length=327, Percent_Identity=26.605504587156, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24646207, Length=413, Percent_Identity=24.455205811138, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21356377, Length=421, Percent_Identity=26.603325415677, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 66600; Mature: 66469

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHYKSNVRDQVFNLFEVLGVDKAFGTDEFSNLDADTAYEMLTEVSRLAEGPVAASFAEG
CCCHHHHHHHHHHHHHHHHCCCHHCCCCHHCCCCHHHHHHHHHHHHHHHCCCCEEEHHCC
DRNPPVFHPETHSITLPESFKKSCRAVAEAGWSKAGIDEALGGTPMPKALLWALHEHLMG
CCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCC
ANPAVWIYAGGAGFANILYHLGTEKQKKWAVWAAERNWGSTMVLTEPDAGSDVGAGRTKA
CCCEEEEEECCCHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCC
VHQEDDSWHIDGVKRFITSGDSDDLFENIFHLVLARPEGAGPGTKGLSLFFVPKFLFDFE
CCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEHEEHHHHHHCCC
TGELGERNGVFVTNVEHKMGLKVSATCELSFGQHGVPAKGWLVGDVHDGIAQMFEVIEQA
CCCCCCCCCEEEEECHHHHCCEEEEEEEECCCCCCCCCCCCEEECHHHHHHHHHHHHHHH
RMMVGTKAIATLSTGYLNALEYAKSRVQGADLTQMTDKTAPRVTITHHPDVRRSLMTQKA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHH
YAEGLRALYLYTATFQDAAVAEAVHGVDAKLAVKINDLMLPLVKGVGSEQAYAKLTESLQ
HHHHHHEEEEEEECCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHH
TLGGSGFLQDYPIEQYIRDAKIDSLYEGTTAIQAQDFFFRKIVRDKGVALSYVSGQIQQF
HCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHCCCEEEHHHHHHHHH
VDSETGNGRLKSERELLAKALTDIQGMEASLTGYLMAAQQDVTSLYKVGLGSVRFLMSVG
HCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DLIIGWLLQRQAAVAVQALDAGASSAERSFYEGKVAVSSFFAKNFLPLLTSTREVLEVLD
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NDIMELDEAAF
HHHHHHHHCCC
>Mature Secondary Structure 
SHYKSNVRDQVFNLFEVLGVDKAFGTDEFSNLDADTAYEMLTEVSRLAEGPVAASFAEG
CCHHHHHHHHHHHHHHHHCCCHHCCCCHHCCCCHHHHHHHHHHHHHHHCCCCEEEHHCC
DRNPPVFHPETHSITLPESFKKSCRAVAEAGWSKAGIDEALGGTPMPKALLWALHEHLMG
CCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCC
ANPAVWIYAGGAGFANILYHLGTEKQKKWAVWAAERNWGSTMVLTEPDAGSDVGAGRTKA
CCCEEEEEECCCHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCC
VHQEDDSWHIDGVKRFITSGDSDDLFENIFHLVLARPEGAGPGTKGLSLFFVPKFLFDFE
CCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEHEEHHHHHHCCC
TGELGERNGVFVTNVEHKMGLKVSATCELSFGQHGVPAKGWLVGDVHDGIAQMFEVIEQA
CCCCCCCCCEEEEECHHHHCCEEEEEEEECCCCCCCCCCCCEEECHHHHHHHHHHHHHHH
RMMVGTKAIATLSTGYLNALEYAKSRVQGADLTQMTDKTAPRVTITHHPDVRRSLMTQKA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHH
YAEGLRALYLYTATFQDAAVAEAVHGVDAKLAVKINDLMLPLVKGVGSEQAYAKLTESLQ
HHHHHHEEEEEEECCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHH
TLGGSGFLQDYPIEQYIRDAKIDSLYEGTTAIQAQDFFFRKIVRDKGVALSYVSGQIQQF
HCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHCCCEEEHHHHHHHHH
VDSETGNGRLKSERELLAKALTDIQGMEASLTGYLMAAQQDVTSLYKVGLGSVRFLMSVG
HCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DLIIGWLLQRQAAVAVQALDAGASSAERSFYEGKVAVSSFFAKNFLPLLTSTREVLEVLD
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NDIMELDEAAF
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8399220; 7857927 [H]