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The map label for this gene is 221230754

Identifier: 221230754

GI number: 221230754

Start: 2846260

End: 2846724

Strand: Direct

Name: 221230754

Synonym: MLBr_02377

Alternate gene names: NA

Gene position: 2846260-2846724 (Clockwise)

Preceding gene: 221230741

Following gene: 221230755

Centisome position: 87.09

GC content: 52.9

Gene sequence:

>465_bases
ATGTCCAAACGCCAACGGGGTAAGGGGATTTCAATTTTCAAGCTGTTGTCACGAATTTGGATTCCACTTGTCATCCTTGT
GGTGCTCGTGGTTGGGGGATTCGTAGTGTACCGTGTCCACAGTTATTTCGCCTCCGAGAAACGCGAATCCTACGCAGATA
GCAACCTGGGAAGCAGCAAGCCGTTCAACCCCAAGCAGATTGTTTACGAGGTCTTCGGCCCACCCGGAACGGTTGCAGAT
ATCAGCTATTTCGATGCTAATTCCGACCCCCAGCGAATCGATGGGGCACAATTGCCATGGTCGTTACTTATGACCACGAC
CTTGGCCGCAGTGATGGGAAACCTCGTGGCTCAGGGCAATACTGATAGTATCGGCTGCCGGATCATCGTGGACGGCGTAG
TCAAAGCTGAGCGAGTTTCCAACGAAGTCAACGCCTACACCTACTGCCTGGTGAAGTCCGCGTGA

Upstream 100 bases:

>100_bases
AACCGACCATCACAAAGGTGTGGCGATCTGAGCTTGTGGTCCGGGTAGTCCGGCACCACGATCTGAAGTTGAACTTGGTC
GAGCGGACATCGGGCCGTCA

Downstream 100 bases:

>100_bases
CGGTCAAATGCGCGAACGACCTGGACACCCACACCAAGCCACCGTTCGTCGCAAGGATGATCCACAGATTTGCGGTACCG
ATCATCTTGGTATGGTTAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MSKRQRGKGISIFKLLSRIWIPLVILVVLVVGGFVVYRVHSYFASEKRESYADSNLGSSKPFNPKQIVYEVFGPPGTVAD
ISYFDANSDPQRIDGAQLPWSLLMTTTLAAVMGNLVAQGNTDSIGCRIIVDGVVKAERVSNEVNAYTYCLVKSA

Sequences:

>Translated_154_residues
MSKRQRGKGISIFKLLSRIWIPLVILVVLVVGGFVVYRVHSYFASEKRESYADSNLGSSKPFNPKQIVYEVFGPPGTVAD
ISYFDANSDPQRIDGAQLPWSLLMTTTLAAVMGNLVAQGNTDSIGCRIIVDGVVKAERVSNEVNAYTYCLVKSA
>Mature_153_residues
SKRQRGKGISIFKLLSRIWIPLVILVVLVVGGFVVYRVHSYFASEKRESYADSNLGSSKPFNPKQIVYEVFGPPGTVADI
SYFDANSDPQRIDGAQLPWSLLMTTTLAAVMGNLVAQGNTDSIGCRIIVDGVVKAERVSNEVNAYTYCLVKSA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpS family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MMPS4_MYCLE (P54880)

Other databases:

- EMBL:   U15183
- EMBL:   AL583925
- PIR:   E87206
- RefSeq:   NP_302540.1
- EnsemblBacteria:   EBMYCT00000028556
- GeneID:   908627
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML2377
- NMPDR:   fig|272631.1.peg.1412
- Leproma:   ML2377
- GeneTree:   EBGT00050000015314
- HOGENOM:   HBG566824
- OMA:   TAVGSIM
- ProtClustDB:   CLSK2299981
- BioCyc:   MLEP272631:ML2377-MONOMER
- InterPro:   IPR008693

Pfam domain/function: PF05423 Mycobact_memb

EC number: NA

Molecular weight: Translated: 16864; Mature: 16732

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x4524c450)-; HASH(0x452b533c)-;

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRQRGKGISIFKLLSRIWIPLVILVVLVVGGFVVYRVHSYFASEKRESYADSNLGSSK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PFNPKQIVYEVFGPPGTVADISYFDANSDPQRIDGAQLPWSLLMTTTLAAVMGNLVAQGN
CCCHHHHHEECCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
TDSIGCRIIVDGVVKAERVSNEVNAYTYCLVKSA
CCCCCEEEEEHHHHHHHHHHHHHCCEEEEEEECH
>Mature Secondary Structure 
SKRQRGKGISIFKLLSRIWIPLVILVVLVVGGFVVYRVHSYFASEKRESYADSNLGSSK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PFNPKQIVYEVFGPPGTVADISYFDANSDPQRIDGAQLPWSLLMTTTLAAVMGNLVAQGN
CCCHHHHHEECCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
TDSIGCRIIVDGVVKAERVSNEVNAYTYCLVKSA
CCCCCEEEEEHHHHHHHHHHHHHCCEEEEEEECH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11234002