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The map label for this gene is asd [H]

Identifier: 221230724

GI number: 221230724

Start: 2751549

End: 2752604

Strand: Reverse

Name: asd [H]

Synonym: MLBr_02322

Alternate gene names: 221230724

Gene position: 2752604-2751549 (Counterclockwise)

Preceding gene: 221230725

Following gene: 221230723

Centisome position: 84.23

GC content: 62.03

Gene sequence:

>1056_bases
ATGGCTACCAGAGGTTTGGCAATCGGGGTAGTGGGTGCCACTGGCCAAGTCGGCCACGTGATGCGCACACTGCTCGAACA
GCGCGATTTCCGGGCCGATTCCGTGCGTTTTTTTGCCTCAGCTCGGTCGCAGGGTCGTAAGTTGGCCTTCCGCGGTCAGA
AAATCGAGGTGGAAGACGCTGAGACGGCCGACCCCACCGGTCTAGACATCGCGTTGTTCTCTGCCGGTGCATCCATGTCT
CGGGTGCAGGCGCCGCGCTTCGCCGCCGCTGGAGTGACGGTAATCGACAATTCGTCGGCGTGGCGCAGGGATGCGCAAGT
GCCGCTGGTGGTGTCCGAGGTGAACTACAACAGGGATGTCCGGGACGCTTTTCCGCTGCCCAAGGGCATCATTGCTAACC
CCAACTGCACCACCATGGTCTCGATGCCGGTGCTCAAGGTGCTGCACGACGAAGCTCAGTTGTTGCGCATGGTGGTGTCG
TCGTATCAAGCGGTCTCTGGCAGTGGTCTGGCTGGGGTAGCCGAGCTGGCCGCTCAGGTGCGTGCGGTTATCGACGTTGC
TGAGCAACTAATACACGACGGTGGTGTCGTGCAATTCCCCGCGCCCAGCAAGTATGTAGCGCCGATAGCCTTCAACGTGG
TGCCCCTGGCCGGATCGCTGGTGGACGACGACTCAGGAGAGACGGATGAGGACCAGAAGCTGCGCTTTGAGAGCTGCAAG
ATTCTGGGCATTCCCGACCTATTGGTTAGCGGTACCTGTGTTCGGGTTCCGGTGTTCACTGGGCATTCGCTGTCGATCAA
TGCCGAATTCGCCCGGCCACTGTCGCCGCAACGAGCCCGCGACCTGCTGGGCGGTGCTCCGGGCGTGAAGCTGGTCGATG
TGCCGACGCCGTTGGCCTCCGCTGGTGTCGACGAATCACTGGTCGGCCGCATCCGGCGCGACCCGGGGGTACCCGACGGG
CGTGGCTTGGCACTGTTCGTCTCTGGTGATAATTTGCGCAAAGGCGCGGCGCTCAATGCGATCCAGATCGCCGAGTTGCT
AGCCACGCAGCTATGA

Upstream 100 bases:

>100_bases
GCCGCGATACCGAACTAGACAAGGCCGTCTTTGCGTTGCATGAGGCGTTTGGACTCGGTGGCGAGGACGAGGTGACGGTG
TACGCGGGGACGGGGAGGTA

Downstream 100 bases:

>100_bases
TCCACGGGTGAGTTTTGCCCGGCTCGTGGAGTGCTCGTGGTATGCCGCTTTGTGTTTGTTTGTCGCACAGGCTTTTTCGG
TTGCTTCTTGGATAGCGCAT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MATRGLAIGVVGATGQVGHVMRTLLEQRDFRADSVRFFASARSQGRKLAFRGQKIEVEDAETADPTGLDIALFSAGASMS
RVQAPRFAAAGVTVIDNSSAWRRDAQVPLVVSEVNYNRDVRDAFPLPKGIIANPNCTTMVSMPVLKVLHDEAQLLRMVVS
SYQAVSGSGLAGVAELAAQVRAVIDVAEQLIHDGGVVQFPAPSKYVAPIAFNVVPLAGSLVDDDSGETDEDQKLRFESCK
ILGIPDLLVSGTCVRVPVFTGHSLSINAEFARPLSPQRARDLLGGAPGVKLVDVPTPLASAGVDESLVGRIRRDPGVPDG
RGLALFVSGDNLRKGAALNAIQIAELLATQL

Sequences:

>Translated_351_residues
MATRGLAIGVVGATGQVGHVMRTLLEQRDFRADSVRFFASARSQGRKLAFRGQKIEVEDAETADPTGLDIALFSAGASMS
RVQAPRFAAAGVTVIDNSSAWRRDAQVPLVVSEVNYNRDVRDAFPLPKGIIANPNCTTMVSMPVLKVLHDEAQLLRMVVS
SYQAVSGSGLAGVAELAAQVRAVIDVAEQLIHDGGVVQFPAPSKYVAPIAFNVVPLAGSLVDDDSGETDEDQKLRFESCK
ILGIPDLLVSGTCVRVPVFTGHSLSINAEFARPLSPQRARDLLGGAPGVKLVDVPTPLASAGVDESLVGRIRRDPGVPDG
RGLALFVSGDNLRKGAALNAIQIAELLATQL
>Mature_350_residues
ATRGLAIGVVGATGQVGHVMRTLLEQRDFRADSVRFFASARSQGRKLAFRGQKIEVEDAETADPTGLDIALFSAGASMSR
VQAPRFAAAGVTVIDNSSAWRRDAQVPLVVSEVNYNRDVRDAFPLPKGIIANPNCTTMVSMPVLKVLHDEAQLLRMVVSS
YQAVSGSGLAGVAELAAQVRAVIDVAEQLIHDGGVVQFPAPSKYVAPIAFNVVPLAGSLVDDDSGETDEDQKLRFESCKI
LGIPDLLVSGTCVRVPVFTGHSLSINAEFARPLSPQRARDLLGGAPGVKLVDVPTPLASAGVDESLVGRIRRDPGVPDGR
GLALFVSGDNLRKGAALNAIQIAELLATQL

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=354, Percent_Identity=31.3559322033898, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789841, Length=365, Percent_Identity=27.1232876712329, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37038; Mature: 36907

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRGLAIGVVGATGQVGHVMRTLLEQRDFRADSVRFFASARSQGRKLAFRGQKIEVEDA
CCCCCEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCEEEECCC
ETADPTGLDIALFSAGASMSRVQAPRFAAAGVTVIDNSSAWRRDAQVPLVVSEVNYNRDV
CCCCCCCCEEEEEECCCCHHHHCCCCEECCCEEEEECCCHHCCCCCCCEEEEECCCCCCH
RDAFPLPKGIIANPNCTTMVSMPVLKVLHDEAQLLRMVVSSYQAVSGSGLAGVAELAAQV
HHHCCCCCCEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
RAVIDVAEQLIHDGGVVQFPAPSKYVAPIAFNVVPLAGSLVDDDSGETDEDQKLRFESCK
HHHHHHHHHHHHCCCEEECCCCCCEECEEEEEEEECCCCEECCCCCCCCHHHHEEHHCEE
ILGIPDLLVSGTCVRVPVFTGHSLSINAEFARPLSPQRARDLLGGAPGVKLVDVPTPLAS
EECCCHHHHCCCEEEEEEEECCEEEEEHHHCCCCCHHHHHHHHCCCCCCEEEECCCCHHH
AGVDESLVGRIRRDPGVPDGRGLALFVSGDNLRKGAALNAIQIAELLATQL
CCCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ATRGLAIGVVGATGQVGHVMRTLLEQRDFRADSVRFFASARSQGRKLAFRGQKIEVEDA
CCCCEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCEEEECCC
ETADPTGLDIALFSAGASMSRVQAPRFAAAGVTVIDNSSAWRRDAQVPLVVSEVNYNRDV
CCCCCCCCEEEEEECCCCHHHHCCCCEECCCEEEEECCCHHCCCCCCCEEEEECCCCCCH
RDAFPLPKGIIANPNCTTMVSMPVLKVLHDEAQLLRMVVSSYQAVSGSGLAGVAELAAQV
HHHCCCCCCEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
RAVIDVAEQLIHDGGVVQFPAPSKYVAPIAFNVVPLAGSLVDDDSGETDEDQKLRFESCK
HHHHHHHHHHHHCCCEEECCCCCCEECEEEEEEEECCCCEECCCCCCCCHHHHEEHHCEE
ILGIPDLLVSGTCVRVPVFTGHSLSINAEFARPLSPQRARDLLGGAPGVKLVDVPTPLAS
EECCCHHHHCCCEEEEEEEECCEEEEEHHHCCCCCHHHHHHHHCCCCCCEEEECCCCHHH
AGVDESLVGRIRRDPGVPDGRGLALFVSGDNLRKGAALNAIQIAELLATQL
CCCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7910936; 12788972 [H]