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The map label for this gene is CYP107B1 [H]

Identifier: 221230605

GI number: 221230605

Start: 2481469

End: 2482773

Strand: Reverse

Name: CYP107B1 [H]

Synonym: MLBr_02088

Alternate gene names: 221230605

Gene position: 2482773-2481469 (Counterclockwise)

Preceding gene: 221230607

Following gene: 221230603

Centisome position: 75.97

GC content: 56.63

Gene sequence:

>1305_bases
ATGCGGACGTGCGTACCAACTCGTACATGCGTGTATGCATTTATCGAGTACCTGAGTCATAATCGACCGATGGGAACGAA
CCCGCCATCGCTTGTTGAGGCACAAATGCTGTTGCTACGCTTGATTGACCCGGGCACCCGGGCGGATCCGTTTCCGGTTT
ATCGCGCGTTAATTGACTACGGGCCGATGCAGCTACCGGGTATGCCGTTGACAGTGTTCTCGTCGTTTTCTGACTGCGAC
GAGGCATTGCGCCATCCGTTGTCGGCCAGCGATCGGCTCAAGGCGACACTAGCGCAGCAGGCCATTGCTGCTGGTGCAGA
ACCGCGACCGTTCTATGCCTCGTCGTTTATGTTTCTCGATCCACCAGATCATACCCGGTTACGCAAGCTTGTCAGCAAGG
CGTTCGCACCGAAAGTCGTTCAGGCGCTGGAAGGTGATATTGCTGCGCTGGTGGATTCCCTGCTGGATAAGGGTGCCGCG
GCTGGCCAGTTTGACGTCATTGCTGACCTAGCCTTTCCGCTTGCGGTGGCTGTGATTTGTCGGCTGCTGGGTGTGCCGTA
CGAAGACGCGCCGGAGTTCGGTCGCGTCTCAGCACTATTGGTGCAGTCAGTCGACCCGTTCATTACCATTACCGGTGAAC
CGCCGGAGGCCACTGAAGAGCGGCTGCGGGCTGGTGTGTGGTTGCGGGATTACTTGGAGCAGCTAGTTAAATGTCGACGC
GGTACACCCGGTGAGGATCTGATATCCAGGCTGATTGAGTTGGACGAGTCGGGTGATCAGCTGACCGAGGAAGAGATCAT
CGCAACGTGCGGTCTGTTGCTCGTTGCTGGTCATGAGACCACGGTGAATCTGATTGCCAATGCGGTCCTGGCGATGTTAC
GCAACCCGTCGCAGTGGAAAGCGCTAAGTAGCAACCCGCAGCGCGCGCCGCTGGTGGTTGAGGAGACGCTTCGTTATGAT
CCAGCAATCCATCTAATCGGTCGGGTAGCTGCTAAGGACATGACGATCGGTCAGACAACTTTAACCGAGGGTGATACAAT
GGTTTTGTTGCTTGCCGCCGCCAATCGCGATCCAGCGGTTTACTCACGCCCCGATGAATTTGACCCCGACCGTCCCAGCT
CACGACATTTGGCATTTGCCGTCGGCTCACATTTTTGCCTAGGAGCGGCATTGGCTCGGTTGGAAGCGACTGTCACATTA
TCTGCGATCAGTGCGCGTTTCCCACAGGTACAGCTGGCCGGTGAATTGGTCTATAAGCCAAATGTGGCAATGCGCGGAAT
GTCGGCACTGCCCGTACAGGTCTGA

Upstream 100 bases:

>100_bases
GCAGAGCAACACCGTTGAGCAGGGCTCTGAATCTGGCCCAAGACTGACGTCGTGGCTCGTAGCGATAAATAATTACGTGT
TCGGCTAGCCACCTTCAATC

Downstream 100 bases:

>100_bases
TGTGTTCGCTAGTGTTGTGTGTTGGTGATTGTTTTAACGTTTGATTTTGTTGAGGGGGTGTCTGCGGTCTGGGTTCAGGT
GAACGGTGTGGTGTGTTCGT

Product: putative cytochrome p450

Products: NA

Alternate protein names: Cytochrome P450CVIIB1 [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRADPFPVYRALIDYGPMQLPGMPLTVFSSFSDCD
EALRHPLSASDRLKATLAQQAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQALEGDIAALVDSLLDKGAA
AGQFDVIADLAFPLAVAVICRLLGVPYEDAPEFGRVSALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRR
GTPGEDLISRLIELDESGDQLTEEEIIATCGLLLVAGHETTVNLIANAVLAMLRNPSQWKALSSNPQRAPLVVEETLRYD
PAIHLIGRVAAKDMTIGQTTLTEGDTMVLLLAAANRDPAVYSRPDEFDPDRPSSRHLAFAVGSHFCLGAALARLEATVTL
SAISARFPQVQLAGELVYKPNVAMRGMSALPVQV

Sequences:

>Translated_434_residues
MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRADPFPVYRALIDYGPMQLPGMPLTVFSSFSDCD
EALRHPLSASDRLKATLAQQAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQALEGDIAALVDSLLDKGAA
AGQFDVIADLAFPLAVAVICRLLGVPYEDAPEFGRVSALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRR
GTPGEDLISRLIELDESGDQLTEEEIIATCGLLLVAGHETTVNLIANAVLAMLRNPSQWKALSSNPQRAPLVVEETLRYD
PAIHLIGRVAAKDMTIGQTTLTEGDTMVLLLAAANRDPAVYSRPDEFDPDRPSSRHLAFAVGSHFCLGAALARLEATVTL
SAISARFPQVQLAGELVYKPNVAMRGMSALPVQV
>Mature_434_residues
MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRADPFPVYRALIDYGPMQLPGMPLTVFSSFSDCD
EALRHPLSASDRLKATLAQQAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQALEGDIAALVDSLLDKGAA
AGQFDVIADLAFPLAVAVICRLLGVPYEDAPEFGRVSALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRR
GTPGEDLISRLIELDESGDQLTEEEIIATCGLLLVAGHETTVNLIANAVLAMLRNPSQWKALSSNPQRAPLVVEETLRYD
PAIHLIGRVAAKDMTIGQTTLTEGDTMVLLLAAANRDPAVYSRPDEFDPDRPSSRHLAFAVGSHFCLGAALARLEATVTL
SAISARFPQVQLAGELVYKPNVAMRGMSALPVQV

Specific function: Not known, probably involved in the catabolism of octane and guaiacol. It displays a weak activity in the O-dealkylation of 7-ethoxycoumarin [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Homo sapiens, GI4503195, Length=357, Percent_Identity=24.6498599439776, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI310125128, Length=218, Percent_Identity=29.8165137614679, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI14550409, Length=218, Percent_Identity=29.8165137614679, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI310125130, Length=218, Percent_Identity=29.8165137614679, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI190570174, Length=218, Percent_Identity=29.8165137614679, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI187960086, Length=203, Percent_Identity=25.1231527093596, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115532670, Length=397, Percent_Identity=24.1813602015113, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71982977, Length=394, Percent_Identity=24.6192893401015, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71982956, Length=394, Percent_Identity=23.8578680203046, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17552522, Length=193, Percent_Identity=27.4611398963731, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17540354, Length=220, Percent_Identity=24.5454545454545, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71990269, Length=268, Percent_Identity=23.5074626865672, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193206712, Length=268, Percent_Identity=23.134328358209, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI17933518, Length=277, Percent_Identity=23.4657039711191, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24642101, Length=173, Percent_Identity=28.9017341040462, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221330299, Length=224, Percent_Identity=22.3214285714286, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21355669, Length=213, Percent_Identity=23.4741784037559, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 47155; Mature: 47155

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRADPFPVYRALIDY
CCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHC
GPMQLPGMPLTVFSSFSDCDEALRHPLSASDRLKATLAQQAIAAGAEPRPFYASSFMFLD
CCCCCCCCCHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCEEEEC
PPDHTRLRKLVSKAFAPKVVQALEGDIAALVDSLLDKGAAAGQFDVIADLAFPLAVAVIC
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
RLLGVPYEDAPEFGRVSALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRR
HHHCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHC
GTPGEDLISRLIELDESGDQLTEEEIIATCGLLLVAGHETTVNLIANAVLAMLRNPSQWK
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCHHHH
ALSSNPQRAPLVVEETLRYDPAIHLIGRVAAKDMTIGQTTLTEGDTMVLLLAAANRDPAV
HHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCCEEEEEEEECCCCCCC
YSRPDEFDPDRPSSRHLAFAVGSHFCLGAALARLEATVTLSAISARFPQVQLAGELVYKP
CCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEECC
NVAMRGMSALPVQV
CHHHCCCCCCCCCC
>Mature Secondary Structure
MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRADPFPVYRALIDY
CCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHC
GPMQLPGMPLTVFSSFSDCDEALRHPLSASDRLKATLAQQAIAAGAEPRPFYASSFMFLD
CCCCCCCCCHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCEEEEC
PPDHTRLRKLVSKAFAPKVVQALEGDIAALVDSLLDKGAAAGQFDVIADLAFPLAVAVIC
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
RLLGVPYEDAPEFGRVSALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRR
HHHCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHC
GTPGEDLISRLIELDESGDQLTEEEIIATCGLLLVAGHETTVNLIANAVLAMLRNPSQWK
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCHHHH
ALSSNPQRAPLVVEETLRYDPAIHLIGRVAAKDMTIGQTTLTEGDTMVLLLAAANRDPAV
HHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCCEEEEEEEECCCCCCC
YSRPDEFDPDRPSSRHLAFAVGSHFCLGAALARLEATVTLSAISARFPQVQLAGELVYKP
CCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEECC
NVAMRGMSALPVQV
CHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732208 [H]