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The map label for this gene is engD [H]

Identifier: 221230518

GI number: 221230518

Start: 2322124

End: 2323194

Strand: Reverse

Name: engD [H]

Synonym: MLBr_01936

Alternate gene names: 221230518

Gene position: 2323194-2322124 (Counterclockwise)

Preceding gene: 221230520

Following gene: 221230515

Centisome position: 71.09

GC content: 59.85

Gene sequence:

>1071_bases
GTGAGCCTGAGTTTGGGAATCGTGGGTCTACCCAACGTCGGCAAGTCGACATTGTTCAACGCGTTGACCAGGAGCAATGT
GGTGGTTGCCAACTATCCGTTTGCAACGATCGAACCGAATGAGGGCGTCGTCTCCCTGCCTGATCCGCGGCTGGCCAAAC
TAGCCGAGTTGTTCGGATCGGAGCGTATCCTGCCGGCCCAGGTGACCTTCGTTGACATTGCCGGCCTGGTAAAGGGTGCG
TCCGAGGGGGCCGGGCTTGGTAACAAGTTTCTGGCCCATATCCGCGAATGCGACGCAATCTGCCAAGTGGTTCGGGTGTT
CTCCGGCGACGACATCACACATGTCACAGGACGCGTGGATCCCCAGTCTGATATCGGGATTATCGATACTGAATTGATCC
TGGCTGACCTGGACACCCTTGAGCGGGCTCTGCCGCGGCTGGAGAAAGAAGCTCGCAACCACAAGGAACGCAAACCCATC
TACGCCGCGGCAATCAACGCACAACAGGTGTTAAACGTCGGGACGACGTTATTCGCCGCCGGTGTAGACGGATCTGCGCT
GCGGGAGCTGAATCTGCTGACCAACAAACCGTTCCTCTACGTTTTCAATGCTGACGAGGCAGTGCTGACCGCTGCCGCAT
GGGTAGCTGAGCTGCGCCAGCTCGTCGCGCCCGCGGATGCGGTGTTCTTGGACGCCGCCATCGAGGCCGAGCTGGCTGAA
TTGGATGACGAGTCGGCCGCTGAGCTACTCGAGTCAATCGGGCAGACCGAGCGGGGGCTCGATGCCCTGGCTCGCGCCGG
TTTCCGCACGCTGGCGCTGCAGACTTTTCTGACGGTGGGACCAAAGGAGGTGCGGGCATGGACCATCCATCAGGGCGATA
CCGCGTCGAAGGCAGCCGGGGTGATTCACACCGACTTCGAGAAGCGTTTCATTAAAGCCGAGATCGTGTCGTATGACGAC
CTGATCGCTACCGGGTCAATGTCGGCAGCAAAGGCGGCAGGTAAGGTCCGAACGGAAGGCAAGGACTACGTGATGGCCGA
CGGCGATGTGGTGGAGTTCCGGCACGGATAA

Upstream 100 bases:

>100_bases
TTATTTAGTATTGACCTCTGGCGTGCCATGTATTCATTCGGGCGTTCCATCCCAGCCGGGGACCGACCATTGTTGAGCTG
AACTCTAGACTTGGTTCCCT

Downstream 100 bases:

>100_bases
ACGTCAAAAAATTTAGTCCGAAGGAACTAACTGGGATTTACCTAGACCGCCATCTCTATCTACTACTTATAACGTAGTAG
ATTTAAACCTGGAAAGGAAA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MSLSLGIVGLPNVGKSTLFNALTRSNVVVANYPFATIEPNEGVVSLPDPRLAKLAELFGSERILPAQVTFVDIAGLVKGA
SEGAGLGNKFLAHIRECDAICQVVRVFSGDDITHVTGRVDPQSDIGIIDTELILADLDTLERALPRLEKEARNHKERKPI
YAAAINAQQVLNVGTTLFAAGVDGSALRELNLLTNKPFLYVFNADEAVLTAAAWVAELRQLVAPADAVFLDAAIEAELAE
LDDESAAELLESIGQTERGLDALARAGFRTLALQTFLTVGPKEVRAWTIHQGDTASKAAGVIHTDFEKRFIKAEIVSYDD
LIATGSMSAAKAAGKVRTEGKDYVMADGDVVEFRHG

Sequences:

>Translated_356_residues
MSLSLGIVGLPNVGKSTLFNALTRSNVVVANYPFATIEPNEGVVSLPDPRLAKLAELFGSERILPAQVTFVDIAGLVKGA
SEGAGLGNKFLAHIRECDAICQVVRVFSGDDITHVTGRVDPQSDIGIIDTELILADLDTLERALPRLEKEARNHKERKPI
YAAAINAQQVLNVGTTLFAAGVDGSALRELNLLTNKPFLYVFNADEAVLTAAAWVAELRQLVAPADAVFLDAAIEAELAE
LDDESAAELLESIGQTERGLDALARAGFRTLALQTFLTVGPKEVRAWTIHQGDTASKAAGVIHTDFEKRFIKAEIVSYDD
LIATGSMSAAKAAGKVRTEGKDYVMADGDVVEFRHG
>Mature_355_residues
SLSLGIVGLPNVGKSTLFNALTRSNVVVANYPFATIEPNEGVVSLPDPRLAKLAELFGSERILPAQVTFVDIAGLVKGAS
EGAGLGNKFLAHIRECDAICQVVRVFSGDDITHVTGRVDPQSDIGIIDTELILADLDTLERALPRLEKEARNHKERKPIY
AAAINAQQVLNVGTTLFAAGVDGSALRELNLLTNKPFLYVFNADEAVLTAAAWVAELRQLVAPADAVFLDAAIEAELAEL
DDESAAELLESIGQTERGLDALARAGFRTLALQTFLTVGPKEVRAWTIHQGDTASKAAGVIHTDFEKRFIKAEIVSYDDL
IATGSMSAAKAAGKVRTEGKDYVMADGDVVEFRHG

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=366, Percent_Identity=42.6229508196721, Blast_Score=276, Evalue=2e-74,
Organism=Homo sapiens, GI58761502, Length=169, Percent_Identity=40.8284023668639, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI24308117, Length=110, Percent_Identity=33.6363636363636, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1787454, Length=359, Percent_Identity=50.1392757660167, Blast_Score=348, Evalue=4e-97,
Organism=Escherichia coli, GI1789574, Length=144, Percent_Identity=35.4166666666667, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17509631, Length=364, Percent_Identity=39.8351648351648, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17508313, Length=104, Percent_Identity=35.5769230769231, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319499, Length=382, Percent_Identity=40.8376963350785, Blast_Score=241, Evalue=1e-64,
Organism=Saccharomyces cerevisiae, GI6321773, Length=390, Percent_Identity=36.1538461538462, Blast_Score=217, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6321649, Length=177, Percent_Identity=33.8983050847458, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640873, Length=365, Percent_Identity=41.3698630136986, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24640877, Length=365, Percent_Identity=41.3698630136986, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24640875, Length=365, Percent_Identity=41.3698630136986, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24640879, Length=323, Percent_Identity=39.0092879256966, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24585318, Length=151, Percent_Identity=31.1258278145695, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20129375, Length=110, Percent_Identity=36.3636363636364, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 38079; Mature: 37947

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSLGIVGLPNVGKSTLFNALTRSNVVVANYPFATIEPNEGVVSLPDPRLAKLAELFGS
CCEEEEEEECCCCCHHHHHHHHHHCCEEEEECCEEEECCCCCEEECCCHHHHHHHHHHCC
ERILPAQVTFVDIAGLVKGASEGAGLGNKFLAHIRECDAICQVVRVFSGDDITHVTGRVD
CCCCEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PQSDIGIIDTELILADLDTLERALPRLEKEARNHKERKPIYAAAINAQQVLNVGTTLFAA
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCHHEEEE
GVDGSALRELNLLTNKPFLYVFNADEAVLTAAAWVAELRQLVAPADAVFLDAAIEAELAE
CCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LDDESAAELLESIGQTERGLDALARAGFRTLALQTFLTVGPKEVRAWTIHQGDTASKAAG
CCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHEEEEEECCCCHHHHCC
VIHTDFEKRFIKAEIVSYDDLIATGSMSAAKAAGKVRTEGKDYVMADGDVVEFRHG
CEECHHHHHHHHHHHHCHHHHHCCCCCHHHHHCCCCCCCCCCEEEECCCEEEECCC
>Mature Secondary Structure 
SLSLGIVGLPNVGKSTLFNALTRSNVVVANYPFATIEPNEGVVSLPDPRLAKLAELFGS
CEEEEEEECCCCCHHHHHHHHHHCCEEEEECCEEEECCCCCEEECCCHHHHHHHHHHCC
ERILPAQVTFVDIAGLVKGASEGAGLGNKFLAHIRECDAICQVVRVFSGDDITHVTGRVD
CCCCEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PQSDIGIIDTELILADLDTLERALPRLEKEARNHKERKPIYAAAINAQQVLNVGTTLFAA
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCHHEEEE
GVDGSALRELNLLTNKPFLYVFNADEAVLTAAAWVAELRQLVAPADAVFLDAAIEAELAE
CCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LDDESAAELLESIGQTERGLDALARAGFRTLALQTFLTVGPKEVRAWTIHQGDTASKAAG
CCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHEEEEEECCCCHHHHCC
VIHTDFEKRFIKAEIVSYDDLIATGSMSAAKAAGKVRTEGKDYVMADGDVVEFRHG
CEECHHHHHHHHHHHHCHHHHHCCCCCHHHHHCCCCCCCCCCEEEECCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA