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The map label for this gene is secY [H]

Identifier: 221230457

GI number: 221230457

Start: 2220681

End: 2221997

Strand: Reverse

Name: secY [H]

Synonym: MLBr_01833

Alternate gene names: 221230457

Gene position: 2221997-2220681 (Counterclockwise)

Preceding gene: 221230458

Following gene: 221230456

Centisome position: 67.99

GC content: 56.34

Gene sequence:

>1317_bases
GTGCTCTCGGCTTTCATCTCGTCGCTGCGGACAGTCGATTTAAGGCGGAAGATCCTTTTCACGCTGGGCATCCTCGTGCT
CTATCGCGTCAGTGCGGCACTGCCCTCTCCGGGCGTCAACTACCGGCACGTGCAGCAATGCATTCAAGAGGCCACCGCCG
GCGAAGCCGGGGAAATTTACTCGCTGATTAACTTGTTCTCCGGTGGTGCGCTGCTAAAGCTCACGGTAGGGGTGATGCCC
TATATCACCGCCAGTATCATTGTGCAGTTGCTGACCGTGGTGATCCCGCGCTTTGAAGAATTACGCAAAGAGGGTCAAGC
AGGCCAAGCGAAAATGACCCAATACACCCGCTATCTGGCTATCGCACTAGCCGTCCTGCAAGCCACCAGCATCGTGGCGC
TGGCGGCCAACGGTGGACTGCTGCAGGGTTGCCAGGAGGACATCATCTCCGACCAGAGCATCTTCAGTCTGGTCGTCATC
GTGCTGGTGATGACGGGCGGTGCGGCGCTGGTGATGTGGATGGGTGAGTTGATCACCGAACGTGGTATCGGCAATGGCAT
GTCGTTATTGATCTTCGTCGGTATCGCTGCCCGCATTCCCGCCGAGGGCAAACAGATCCTAGATAGCCGGGGTGGGGTCA
TCTTTGCCGCTGTTTGCCTGGCCGCACTGGTCATCATCGTTGGCGTGGTCTTCGTTGAGCAGGGCCAGCGCCGAATCCCG
GTGCAATACGCTAAGCGCATGGTGGGTCGGCGGATGTATGGCGGGACCTCAACATACCTGCCGCTCAAGGTCAATCAGGC
CGGCGTTATTCCGGTAATCTTCGCGTCGTCGTTAATCTACATTCCACATCTGATCACCCAGCTGGTCCGCAGCGGCAGCG
GTGGTGTGGGCAAGAGCTGGTGGGACAAATTCGTCGGCACCTACCTATCGGATCCGGCCGATCCCGTTTATATCAACATA
TACTTCGGGCTTATCATCTTCTTCACCTACTTCTATGTATCGGTAACATTCAATCCCGACGAACGTGCCGACGAGATGAA
GAAGTTCGGTGGTTTCATTCCTGGCATTCGACCGGGACGGCCGACGGCGGACTATTTGCGTTATGTGCTAAGCCGAATTA
CGTTGCCGGGATCGATCTATCTTGGAGCGATCGCGGTGTTGCCCAATCTATTCCTGCAGATCGGCAATGGCGGCGAGGTC
CAGAATTTACCGTTCGGGGGAACCGCTGTGTTGATCATGATCGGTGTTGGCTTGGATACGGTCAAGCAGATCGAGAGTCA
GCTGATGCAACGCAACTATGAAGGGTTCCTGAAGTGA

Upstream 100 bases:

>100_bases
GTATGATGCGCGAGACGCAGGATAACCCCCGGAAATCGATGCCAGCCGGACCAGCCTGGTTGGCATGTCGCGAAAAGAGT
TTGGCTGCGCAGGAGGAAGA

Downstream 100 bases:

>100_bases
GAGTTGTTTTGCTGGGACCGCCGGGGGCAGGCAAGGGCACGCAAGCCCAAAGGCTCGCCGAGAAGCTTGGTATCCCGCAG
ATCTCCACCGGTGAATTGTT

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MLSAFISSLRTVDLRRKILFTLGILVLYRVSAALPSPGVNYRHVQQCIQEATAGEAGEIYSLINLFSGGALLKLTVGVMP
YITASIIVQLLTVVIPRFEELRKEGQAGQAKMTQYTRYLAIALAVLQATSIVALAANGGLLQGCQEDIISDQSIFSLVVI
VLVMTGGAALVMWMGELITERGIGNGMSLLIFVGIAARIPAEGKQILDSRGGVIFAAVCLAALVIIVGVVFVEQGQRRIP
VQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLITQLVRSGSGGVGKSWWDKFVGTYLSDPADPVYINI
YFGLIIFFTYFYVSVTFNPDERADEMKKFGGFIPGIRPGRPTADYLRYVLSRITLPGSIYLGAIAVLPNLFLQIGNGGEV
QNLPFGGTAVLIMIGVGLDTVKQIESQLMQRNYEGFLK

Sequences:

>Translated_438_residues
MLSAFISSLRTVDLRRKILFTLGILVLYRVSAALPSPGVNYRHVQQCIQEATAGEAGEIYSLINLFSGGALLKLTVGVMP
YITASIIVQLLTVVIPRFEELRKEGQAGQAKMTQYTRYLAIALAVLQATSIVALAANGGLLQGCQEDIISDQSIFSLVVI
VLVMTGGAALVMWMGELITERGIGNGMSLLIFVGIAARIPAEGKQILDSRGGVIFAAVCLAALVIIVGVVFVEQGQRRIP
VQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLITQLVRSGSGGVGKSWWDKFVGTYLSDPADPVYINI
YFGLIIFFTYFYVSVTFNPDERADEMKKFGGFIPGIRPGRPTADYLRYVLSRITLPGSIYLGAIAVLPNLFLQIGNGGEV
QNLPFGGTAVLIMIGVGLDTVKQIESQLMQRNYEGFLK
>Mature_438_residues
MLSAFISSLRTVDLRRKILFTLGILVLYRVSAALPSPGVNYRHVQQCIQEATAGEAGEIYSLINLFSGGALLKLTVGVMP
YITASIIVQLLTVVIPRFEELRKEGQAGQAKMTQYTRYLAIALAVLQATSIVALAANGGLLQGCQEDIISDQSIFSLVVI
VLVMTGGAALVMWMGELITERGIGNGMSLLIFVGIAARIPAEGKQILDSRGGVIFAAVCLAALVIIVGVVFVEQGQRRIP
VQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLITQLVRSGSGGVGKSWWDKFVGTYLSDPADPVYINI
YFGLIIFFTYFYVSVTFNPDERADEMKKFGGFIPGIRPGRPTADYLRYVLSRITLPGSIYLGAIAVLPNLFLQIGNGGEV
QNLPFGGTAVLIMIGVGLDTVKQIESQLMQRNYEGFLK

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=437, Percent_Identity=41.6475972540046, Blast_Score=287, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 47519; Mature: 47519

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSAFISSLRTVDLRRKILFTLGILVLYRVSAALPSPGVNYRHVQQCIQEATAGEAGEIY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHH
SLINLFSGGALLKLTVGVMPYITASIIVQLLTVVIPRFEELRKEGQAGQAKMTQYTRYLA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
IALAVLQATSIVALAANGGLLQGCQEDIISDQSIFSLVVIVLVMTGGAALVMWMGELITE
HHHHHHHHHHHEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RGIGNGMSLLIFVGIAARIPAEGKQILDSRGGVIFAAVCLAALVIIVGVVFVEQGQRRIP
CCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLITQLVRSGSGGVGKSW
HHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
WDKFVGTYLSDPADPVYINIYFGLIIFFTYFYVSVTFNPDERADEMKKFGGFIPGIRPGR
HHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCCCCCCCCCC
PTADYLRYVLSRITLPGSIYLGAIAVLPNLFLQIGNGGEVQNLPFGGTAVLIMIGVGLDT
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEEHEECCCHHH
VKQIESQLMQRNYEGFLK
HHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MLSAFISSLRTVDLRRKILFTLGILVLYRVSAALPSPGVNYRHVQQCIQEATAGEAGEIY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHH
SLINLFSGGALLKLTVGVMPYITASIIVQLLTVVIPRFEELRKEGQAGQAKMTQYTRYLA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
IALAVLQATSIVALAANGGLLQGCQEDIISDQSIFSLVVIVLVMTGGAALVMWMGELITE
HHHHHHHHHHHEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RGIGNGMSLLIFVGIAARIPAEGKQILDSRGGVIFAAVCLAALVIIVGVVFVEQGQRRIP
CCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLITQLVRSGSGGVGKSW
HHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
WDKFVGTYLSDPADPVYINIYFGLIIFFTYFYVSVTFNPDERADEMKKFGGFIPGIRPGR
HHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCCCCCCCCCC
PTADYLRYVLSRITLPGSIYLGAIAVLPNLFLQIGNGGEVQNLPFGGTAVLIMIGVGLDT
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEEHEECCCHHH
VKQIESQLMQRNYEGFLK
HHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9350347; 12788972 [H]