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The map label for this gene is trxB [C]

Identifier: 221230451

GI number: 221230451

Start: 2201448

End: 2201840

Strand: Reverse

Name: trxB [C]

Synonym: MLBr_01818

Alternate gene names: 221230451

Gene position: 2201840-2201448 (Counterclockwise)

Preceding gene: 221230452

Following gene: 221230450

Centisome position: 67.37

GC content: 54.96

Gene sequence:

>393_bases
ATGGTCCGGGAACATGGCGTCGGTGTGCGACGTTGGACTAGACGTGACCTTATTGCTGAACAGTTAAACGAAACCATCAA
CGTCAACAACATGGTGCTTGTCGCCTTTTGGGCGTCCTGGTGCGGACCAGATCGATTGTTTGTGCCGACGTTTCACGCGT
CGTCGAATAAGCACTCTGATGTCGTGCACTTAAACGTAGACACCAAAGCCGAAAGGCAACTGGCATTAGCAGCTCAGATC
AGGTCCATCCCCACGTTGGTGGCCTTCAAGAAGGGCAAGCCGCTGTTGAGTCAGGCTGGGGATCTGACGCCGGCGGTGCC
GGGGTATTTGGTGCAACAAATCAAGGCCTTCGACGTCTCCGACGATGGGGTCGTGCCAGACGAACAGGTCTAA

Upstream 100 bases:

>100_bases
ACGGCCGGCCACGAAGGATCGACAGTGCTCAGCGGCATGTGTTTGCCCATCAACCGGTCGTGGCGGGCCGCGGCGTCCAC
CAGTGTGCTGAGGCCGGTGA

Downstream 100 bases:

>100_bases
TCAGAATGTGCGTGGGCGGCGTTGGCACGGATCGACCGTGTACAGTGGGAGGCGCTTTGCGCGTTAATTTTCAACGGTGC
CTTTTGTACTTGTTGATTAC

Product: thioredoxin

Products: NA

Alternate protein names: Thiol-Disulfide Isomerase; Thioredoxin TrxA; Thiredoxine; Thioredoxin TrxB; Thioredoxin Domain-Containing Protein; Thioredoxin Domain Protein; Thioredoxin TRXA; Thioredoxin-Disulfide Reductase; Thiol-Disulfide Isomerase And Thioredoxins

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MVREHGVGVRRWTRRDLIAEQLNETINVNNMVLVAFWASWCGPDRLFVPTFHASSNKHSDVVHLNVDTKAERQLALAAQI
RSIPTLVAFKKGKPLLSQAGDLTPAVPGYLVQQIKAFDVSDDGVVPDEQV

Sequences:

>Translated_130_residues
MVREHGVGVRRWTRRDLIAEQLNETINVNNMVLVAFWASWCGPDRLFVPTFHASSNKHSDVVHLNVDTKAERQLALAAQI
RSIPTLVAFKKGKPLLSQAGDLTPAVPGYLVQQIKAFDVSDDGVVPDEQV
>Mature_130_residues
MVREHGVGVRRWTRRDLIAEQLNETINVNNMVLVAFWASWCGPDRLFVPTFHASSNKHSDVVHLNVDTKAERQLALAAQI
RSIPTLVAFKKGKPLLSQAGDLTPAVPGYLVQQIKAFDVSDDGVVPDEQV

Specific function: Efficient Electron Donor For The Essential Enzyme Ribonucleotide Reductase. Is Also Able To Reduce The Interchain Disulfide Bridges Of Insulin. [C]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788936, Length=76, Percent_Identity=40.7894736842105, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 14429; Mature: 14429

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVREHGVGVRRWTRRDLIAEQLNETINVNNMVLVAFWASWCGPDRLFVPTFHASSNKHSD
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHCCCCCEEEEEECCCCCCCCC
VVHLNVDTKAERQLALAAQIRSIPTLVAFKKGKPLLSQAGDLTPAVPGYLVQQIKAFDVS
EEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHCCCCCCCCHHHHHHHHHHCCCC
DDGVVPDEQV
CCCCCCCCCC
>Mature Secondary Structure
MVREHGVGVRRWTRRDLIAEQLNETINVNNMVLVAFWASWCGPDRLFVPTFHASSNKHSD
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHCCCCCEEEEEECCCCCCCCC
VVHLNVDTKAERQLALAAQIRSIPTLVAFKKGKPLLSQAGDLTPAVPGYLVQQIKAFDVS
EEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHCCCCCCCCHHHHHHHHHHCCCC
DDGVVPDEQV
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA