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The map label for this gene is ycgM [C]

Identifier: 221230375

GI number: 221230375

Start: 2035016

End: 2035744

Strand: Reverse

Name: ycgM [C]

Synonym: MLBr_01689

Alternate gene names: 221230375

Gene position: 2035744-2035016 (Counterclockwise)

Preceding gene: 221230376

Following gene: 221230374

Centisome position: 62.29

GC content: 57.75

Gene sequence:

>729_bases
ATGTTTGCCCGTGAGCTCGCTGAGTACCCATTCGGCGAGTTAACCTTCACTGGCCGTTCGTGGCCATTAGCCGATGTCCG
GCTACTGGCTCCGATGCTGGCCAGCAAGGTGGTCTGTATCGGTAAGAACTACGCCGATCATATCGTCGAGATGGGTGGCC
AAACGGGACTAGCTTCGGCAGATCCGGTGATATTCCTCAAGCCCAATACCGCGATCATCGGGCCAAATGTTCCGATTCGA
CTGCCTGCCAACGCATCACCTGTGCATTTCGAGGGCGAGTTGGCACTCGTGGTGGGCCGGTCGTGCAAGGACGTCCCGGC
AGTCCAGGCCGTCGACTGCATTCTCGGCTATACCATCGGCAACGACATGTCGGCTCGCGATCAACAACGCGCGGATGGTC
AATGGACCCGCGCGAAAGGACATGATACCTTCTGCCCAGTAGGGCCGTGGATCGTCACCGACCTCGGTCCCCTAGACCCA
GCCGATCTTGAACTGCGAACCGCAGTCAACGGCGAAGTTAAACAACACAGCCGCACCTCCCTGATGATTCACGGCATCGG
TGCCATCATGGAGTGGATCTCGGCGGTAATGACATTGCTGCCCGGTGATCTCATACTCACCGGGACACCGGCAGGTGTTG
GTCCCGTCGAAGACGGTGACATCGTTTCTATCACTGTCGAAGGCATCGGAACTCTTACCAATCCCGTAGTCCGCAAAGGA
AAGTCGTGA

Upstream 100 bases:

>100_bases
TCGTTACGCTAGTCTCAAGTAAATGCGTCTTGGTCGAATATCTAGTCCAGATGGCGTCGCGTTCGTCAGCATCGAAGGTG
AGCCTGACGATCCCGATGGG

Downstream 100 bases:

>100_bases
CTGCAGTAACCTCTGATGGTACCCCGCAAGCAGCAAAAGTCAGGGTACGATTCTGCCCATCGCCCACTGGTGTTCCGCAC
GTCGGGATGGTTCGCACGGC

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MFARELAEYPFGELTFTGRSWPLADVRLLAPMLASKVVCIGKNYADHIVEMGGQTGLASADPVIFLKPNTAIIGPNVPIR
LPANASPVHFEGELALVVGRSCKDVPAVQAVDCILGYTIGNDMSARDQQRADGQWTRAKGHDTFCPVGPWIVTDLGPLDP
ADLELRTAVNGEVKQHSRTSLMIHGIGAIMEWISAVMTLLPGDLILTGTPAGVGPVEDGDIVSITVEGIGTLTNPVVRKG
KS

Sequences:

>Translated_242_residues
MFARELAEYPFGELTFTGRSWPLADVRLLAPMLASKVVCIGKNYADHIVEMGGQTGLASADPVIFLKPNTAIIGPNVPIR
LPANASPVHFEGELALVVGRSCKDVPAVQAVDCILGYTIGNDMSARDQQRADGQWTRAKGHDTFCPVGPWIVTDLGPLDP
ADLELRTAVNGEVKQHSRTSLMIHGIGAIMEWISAVMTLLPGDLILTGTPAGVGPVEDGDIVSITVEGIGTLTNPVVRKG
KS
>Mature_242_residues
MFARELAEYPFGELTFTGRSWPLADVRLLAPMLASKVVCIGKNYADHIVEMGGQTGLASADPVIFLKPNTAIIGPNVPIR
LPANASPVHFEGELALVVGRSCKDVPAVQAVDCILGYTIGNDMSARDQQRADGQWTRAKGHDTFCPVGPWIVTDLGPLDP
ADLELRTAVNGEVKQHSRTSLMIHGIGAIMEWISAVMTLLPGDLILTGTPAGVGPVEDGDIVSITVEGIGTLTNPVVRKG
KS

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI40786394, Length=226, Percent_Identity=40.7079646017699, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI156231349, Length=226, Percent_Identity=41.1504424778761, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI13654274, Length=206, Percent_Identity=40.7766990291262, Blast_Score=155, Evalue=3e-38,
Organism=Homo sapiens, GI215422413, Length=202, Percent_Identity=40.5940594059406, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI66348062, Length=197, Percent_Identity=41.6243654822335, Blast_Score=152, Evalue=2e-37,
Organism=Escherichia coli, GI1787428, Length=198, Percent_Identity=38.3838383838384, Blast_Score=142, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17557057, Length=197, Percent_Identity=37.0558375634518, Blast_Score=133, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6324161, Length=224, Percent_Identity=34.375, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28572127, Length=223, Percent_Identity=38.5650224215247, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28571789, Length=203, Percent_Identity=33.9901477832512, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24663695, Length=223, Percent_Identity=33.1838565022422, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 25674; Mature: 25674

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFARELAEYPFGELTFTGRSWPLADVRLLAPMLASKVVCIGKNYADHIVEMGGQTGLASA
CCHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCEEEECCCHHHHHHHCCCCCCCCCC
DPVIFLKPNTAIIGPNVPIRLPANASPVHFEGELALVVGRSCKDVPAVQAVDCILGYTIG
CCEEEECCCCEEECCCCCEEECCCCCCEEECCCEEEEECCCCCCCCHHHHHHHHHHEECC
NDMSARDQQRADGQWTRAKGHDTFCPVGPWIVTDLGPLDPADLELRTAVNGEVKQHSRTS
CCCCCCHHHHCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCCHHHCCCCE
LMIHGIGAIMEWISAVMTLLPGDLILTGTPAGVGPVEDGDIVSITVEGIGTLTNPVVRKG
EEEECHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHCC
KS
CC
>Mature Secondary Structure
MFARELAEYPFGELTFTGRSWPLADVRLLAPMLASKVVCIGKNYADHIVEMGGQTGLASA
CCHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCEEEECCCHHHHHHHCCCCCCCCCC
DPVIFLKPNTAIIGPNVPIRLPANASPVHFEGELALVVGRSCKDVPAVQAVDCILGYTIG
CCEEEECCCCEEECCCCCEEECCCCCCEEECCCEEEEECCCCCCCCHHHHHHHHHHEECC
NDMSARDQQRADGQWTRAKGHDTFCPVGPWIVTDLGPLDPADLELRTAVNGEVKQHSRTS
CCCCCCHHHHCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCCHHHCCCCE
LMIHGIGAIMEWISAVMTLLPGDLILTGTPAGVGPVEDGDIVSITVEGIGTLTNPVVRKG
EEEECHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHCC
KS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]