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The map label for this gene is gpsA [H]

Identifier: 221230367

GI number: 221230367

Start: 2023012

End: 2024067

Strand: Reverse

Name: gpsA [H]

Synonym: MLBr_01679

Alternate gene names: 221230367

Gene position: 2024067-2023012 (Counterclockwise)

Preceding gene: 221230371

Following gene: 221230366

Centisome position: 61.93

GC content: 63.92

Gene sequence:

>1056_bases
GTGGAGATGGCCGGCATAGTGGTCCGTTCAGAGAGTGCTGTCGCGGTGATGGGCGCTGGTGCATGGGGCACTGCACTGGC
CAAGGTGCTTATCGATGCCGGCGGACCGGAGGCCGGAGTCGTATTGTGGGCTCGGCGACCGGATGTCGCTGAGCGGATCA
ATACCACCCGATGTAACCGCGCCTATCTACCGGGAACACTGCTTCCGCCAGGTATCCGCGCTACCGCCGATCCAGCAGAT
GCGCTGCGCGGTGCGTCGACGGTGCTATTGGGGGTGCCGGCGCAGCGGATGCGGGCCAACCTCGAGCGGTGGGGTGGTTT
GGTGGCCGACGGCGCGACCCTGGTGAGTCTGGCAAAAGGCATCGAGCTGGGCACGCTGATGCGGATGAGTCAGGTCATTG
TCTCGGTAACTGGCGTGGACCCGGCGCAGGTCGCGGTGCTTTCGGGACCCAACCTGGCTAGCGAGATTGCTCAATGCCAG
CCCGCAGCCACCGTCATCGCGTGCAGCGACTTGGGCCGAGCCGTCGCTTTGCAGCGCATGCTAAGCAGTGGCTACTTTCG
GCCGTACACCAACAGCGATGTCGTCGGCACCGAGATCGGCGGGGTATGCAAGAACGTCATAGCGCTGGCGTGCGGGATGG
CTGCGGGTGTCGGGTTCGGCGAAAACACCGCGGCGACGATCATTACTCGGGGCCTGGCGGAGATCATCCGGCTGGGGATG
GCGCTAGGCGCCCAGGTTACTACGTTGGCCGGTCTGGCGGGGGTAGGTGATTTGGTGGCCACCTGCACATCGCCGCATTC
GCGTAACCGGTCACTCGGCGAACGCTTGGGCCGGGGCGAGATCATGCAGTCGATCTTGCACGGTATGGATGGTTCCGATG
GCGGAGACGGCTACGTCGTCGAGGGTGTGACGTCGTGCGCGTCGGTACTCGCGCTAGCGTCCAGTTATGACGTCGAGATG
CCGCTAACTGACGCCGTCCACCGAGTTTGTCACAAGGGACTCTCGGTCGAGAAGGCGATGGCTCTGCTGTTGGGCCGCAG
TACTAAGTCTGAGTAA

Upstream 100 bases:

>100_bases
CAGCGCCACGTTAGCGCGTGATCGTGACTAGCGTGACGATAGCCCGTGTTGGTCTGTGCCGTACCTGCTGCAGATGCCGC
TTTAAACAACTACGGGGGTG

Downstream 100 bases:

>100_bases
CCACGCCGGAATGTGACGGGGCCCGCCCAGGTGGACCGTGAGTAGCCTAGAAGGCCTAGTTCAGAGTTTTAGCTGCTCTT
GGAGCTGCTTGACCGGTAGC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MEMAGIVVRSESAVAVMGAGAWGTALAKVLIDAGGPEAGVVLWARRPDVAERINTTRCNRAYLPGTLLPPGIRATADPAD
ALRGASTVLLGVPAQRMRANLERWGGLVADGATLVSLAKGIELGTLMRMSQVIVSVTGVDPAQVAVLSGPNLASEIAQCQ
PAATVIACSDLGRAVALQRMLSSGYFRPYTNSDVVGTEIGGVCKNVIALACGMAAGVGFGENTAATIITRGLAEIIRLGM
ALGAQVTTLAGLAGVGDLVATCTSPHSRNRSLGERLGRGEIMQSILHGMDGSDGGDGYVVEGVTSCASVLALASSYDVEM
PLTDAVHRVCHKGLSVEKAMALLLGRSTKSE

Sequences:

>Translated_351_residues
MEMAGIVVRSESAVAVMGAGAWGTALAKVLIDAGGPEAGVVLWARRPDVAERINTTRCNRAYLPGTLLPPGIRATADPAD
ALRGASTVLLGVPAQRMRANLERWGGLVADGATLVSLAKGIELGTLMRMSQVIVSVTGVDPAQVAVLSGPNLASEIAQCQ
PAATVIACSDLGRAVALQRMLSSGYFRPYTNSDVVGTEIGGVCKNVIALACGMAAGVGFGENTAATIITRGLAEIIRLGM
ALGAQVTTLAGLAGVGDLVATCTSPHSRNRSLGERLGRGEIMQSILHGMDGSDGGDGYVVEGVTSCASVLALASSYDVEM
PLTDAVHRVCHKGLSVEKAMALLLGRSTKSE
>Mature_351_residues
MEMAGIVVRSESAVAVMGAGAWGTALAKVLIDAGGPEAGVVLWARRPDVAERINTTRCNRAYLPGTLLPPGIRATADPAD
ALRGASTVLLGVPAQRMRANLERWGGLVADGATLVSLAKGIELGTLMRMSQVIVSVTGVDPAQVAVLSGPNLASEIAQCQ
PAATVIACSDLGRAVALQRMLSSGYFRPYTNSDVVGTEIGGVCKNVIALACGMAAGVGFGENTAATIITRGLAEIIRLGM
ALGAQVTTLAGLAGVGDLVATCTSPHSRNRSLGERLGRGEIMQSILHGMDGSDGGDGYVVEGVTSCASVLALASSYDVEM
PLTDAVHRVCHKGLSVEKAMALLLGRSTKSE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=343, Percent_Identity=31.7784256559767, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI24307999, Length=347, Percent_Identity=27.6657060518732, Blast_Score=119, Evalue=5e-27,
Organism=Escherichia coli, GI1790037, Length=344, Percent_Identity=39.5348837209302, Blast_Score=216, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI32564399, Length=350, Percent_Identity=27.1428571428571, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32564403, Length=359, Percent_Identity=26.7409470752089, Blast_Score=120, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI193210136, Length=355, Percent_Identity=26.7605633802817, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17507425, Length=344, Percent_Identity=28.4883720930233, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI193210134, Length=343, Percent_Identity=25.6559766763848, Blast_Score=91, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324513, Length=361, Percent_Identity=29.0858725761773, Blast_Score=134, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6320181, Length=357, Percent_Identity=29.9719887955182, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI17136202, Length=342, Percent_Identity=28.3625730994152, Blast_Score=120, Evalue=9e-28,
Organism=Drosophila melanogaster, GI17136200, Length=342, Percent_Identity=28.3625730994152, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17136204, Length=342, Percent_Identity=28.3625730994152, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI22026922, Length=347, Percent_Identity=26.8011527377522, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI45551945, Length=332, Percent_Identity=25.9036144578313, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281362270, Length=261, Percent_Identity=27.5862068965517, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24648969, Length=293, Percent_Identity=25.938566552901, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 35879; Mature: 35879

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMAGIVVRSESAVAVMGAGAWGTALAKVLIDAGGPEAGVVLWARRPDVAERINTTRCNR
CCCCCEEEECCCEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHCCCCCCC
AYLPGTLLPPGIRATADPADALRGASTVLLGVPAQRMRANLERWGGLVADGATLVSLAKG
CCCCCCCCCCCCCCCCCHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHC
IELGTLMRMSQVIVSVTGVDPAQVAVLSGPNLASEIAQCQPAATVIACSDLGRAVALQRM
CHHHHHHHHHHHHHHHCCCCHHHEEEECCCCHHHHHHHCCCCHHEEEHHHHHHHHHHHHH
LSSGYFRPYTNSDVVGTEIGGVCKNVIALACGMAAGVGFGENTAATIITRGLAEIIRLGM
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
ALGAQVTTLAGLAGVGDLVATCTSPHSRNRSLGERLGRGEIMQSILHGMDGSDGGDGYVV
HHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEE
EGVTSCASVLALASSYDVEMPLTDAVHRVCHKGLSVEKAMALLLGRSTKSE
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEMAGIVVRSESAVAVMGAGAWGTALAKVLIDAGGPEAGVVLWARRPDVAERINTTRCNR
CCCCCEEEECCCEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHCCCCCCC
AYLPGTLLPPGIRATADPADALRGASTVLLGVPAQRMRANLERWGGLVADGATLVSLAKG
CCCCCCCCCCCCCCCCCHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHC
IELGTLMRMSQVIVSVTGVDPAQVAVLSGPNLASEIAQCQPAATVIACSDLGRAVALQRM
CHHHHHHHHHHHHHHHCCCCHHHEEEECCCCHHHHHHHCCCCHHEEEHHHHHHHHHHHHH
LSSGYFRPYTNSDVVGTEIGGVCKNVIALACGMAAGVGFGENTAATIITRGLAEIIRLGM
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
ALGAQVTTLAGLAGVGDLVATCTSPHSRNRSLGERLGRGEIMQSILHGMDGSDGGDGYVV
HHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEE
EGVTSCASVLALASSYDVEMPLTDAVHRVCHKGLSVEKAMALLLGRSTKSE
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]