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The map label for this gene is pknE [H]

Identifier: 221230360

GI number: 221230360

Start: 2010181

End: 2010975

Strand: Reverse

Name: pknE [H]

Synonym: MLBr_01667

Alternate gene names: 221230360

Gene position: 2010975-2010181 (Counterclockwise)

Preceding gene: 221230362

Following gene: 221230359

Centisome position: 61.53

GC content: 59.12

Gene sequence:

>795_bases
GTGAGGATCAGCGAACCTGTGGCCGATAACCGCAAACGTCTTCAGCGATTCGACCTAAAGTCGGTAGACGGCCGGTCTGG
CCGGGCTGTCGTGATCGCCGGCACTGTGATTGTCGCGATCTTCGCGGTTGTCGTCGTCTTCGCCGTCATGAAATCGCAGC
ATGCCAAGCAAGATGGCGCGGCCCCGCTGACCGGCTCGGGTGACACGGTGCGGGTGACTTCGAGCAAGTTAGTCACCCAG
CCCGGCACCCACGACCCCAAGGTCGTGATGTCTTTTTACGAGGACTTCCTGTGCCCGGGGTGCGGTGATTTCGAGCGGAA
TTTTGGGCCTACGGTGTCCAAGCTCATCGACATCGGTGCGATTGCGGCCGATTACTCCGTGGTGTCCATTCTTGACCACC
CACGTAACCATAACTATCCGTCACGGGCAGGTGCGGCGTCCTTGTGCGTAGCCGATGAATCCATGGATGCTTACCGTCGG
TTCCGTGCTGCGTTGTACAGTCGCAGCTTCCAACCCAGTGAACTTGCGAGCAGTTTCCCTGAGAATGCGAAGTTGATCGA
AATCGCGCGGGAAGCCGGCGTGGTTGGGAAGGTCCCGGACTGTATTAACAGCGGGAAGTACCTGGCCAAGGTCACCGCAG
AAGCAGCGCTCGCGAAGATCTCGGCAACCCCGACGATCAAGATCAACGGCGACGAATACGACCCGTTGACACCCGAAGCA
CTGGTGGCCAAGATTAAAGCAATCGTGGGCGCCGTCCCGGGCATCGACGTGGCTGTCACTGCTACGACAACGTAA

Upstream 100 bases:

>100_bases
GCACTGCGTGCTCACCTGAGCCGGGTATAGTTACCCAATTCACCGTCGCCGGTACTCTAGAGACGCCGTCGCCCGATCGT
GATCGGGCCAAATCGAGCAC

Downstream 100 bases:

>100_bases
CTTACGCGGTGTCAGCACAACCTGTCGAGCGTCCCGGCGACCTGAAACCGGCTCCGGCTAGCGTGTTGCCGATGCCGGTG
CCCACCGCATGGTGGGTGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MRISEPVADNRKRLQRFDLKSVDGRSGRAVVIAGTVIVAIFAVVVVFAVMKSQHAKQDGAAPLTGSGDTVRVTSSKLVTQ
PGTHDPKVVMSFYEDFLCPGCGDFERNFGPTVSKLIDIGAIAADYSVVSILDHPRNHNYPSRAGAASLCVADESMDAYRR
FRAALYSRSFQPSELASSFPENAKLIEIAREAGVVGKVPDCINSGKYLAKVTAEAALAKISATPTIKINGDEYDPLTPEA
LVAKIKAIVGAVPGIDVAVTATTT

Sequences:

>Translated_264_residues
MRISEPVADNRKRLQRFDLKSVDGRSGRAVVIAGTVIVAIFAVVVVFAVMKSQHAKQDGAAPLTGSGDTVRVTSSKLVTQ
PGTHDPKVVMSFYEDFLCPGCGDFERNFGPTVSKLIDIGAIAADYSVVSILDHPRNHNYPSRAGAASLCVADESMDAYRR
FRAALYSRSFQPSELASSFPENAKLIEIAREAGVVGKVPDCINSGKYLAKVTAEAALAKISATPTIKINGDEYDPLTPEA
LVAKIKAIVGAVPGIDVAVTATTT
>Mature_264_residues
MRISEPVADNRKRLQRFDLKSVDGRSGRAVVIAGTVIVAIFAVVVVFAVMKSQHAKQDGAAPLTGSGDTVRVTSSKLVTQ
PGTHDPKVVMSFYEDFLCPGCGDFERNFGPTVSKLIDIGAIAADYSVVSILDHPRNHNYPSRAGAASLCVADESMDAYRR
FRAALYSRSFQPSELASSFPENAKLIEIAREAGVVGKVPDCINSGKYLAKVTAEAALAKISATPTIKINGDEYDPLTPEA
LVAKIKAIVGAVPGIDVAVTATTT

Specific function: Unknown

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 28012; Mature: 28012

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRISEPVADNRKRLQRFDLKSVDGRSGRAVVIAGTVIVAIFAVVVVFAVMKSQHAKQDGA
CCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
APLTGSGDTVRVTSSKLVTQPGTHDPKVVMSFYEDFLCPGCGDFERNFGPTVSKLIDIGA
CCCCCCCCEEEEECCEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHH
IAADYSVVSILDHPRNHNYPSRAGAASLCVADESMDAYRRFRAALYSRSFQPSELASSFP
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHCC
ENAKLIEIAREAGVVGKVPDCINSGKYLAKVTAEAALAKISATPTIKINGDEYDPLTPEA
CCCHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHH
LVAKIKAIVGAVPGIDVAVTATTT
HHHHHHHHHHCCCCCCEEEEEECC
>Mature Secondary Structure
MRISEPVADNRKRLQRFDLKSVDGRSGRAVVIAGTVIVAIFAVVVVFAVMKSQHAKQDGA
CCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
APLTGSGDTVRVTSSKLVTQPGTHDPKVVMSFYEDFLCPGCGDFERNFGPTVSKLIDIGA
CCCCCCCCEEEEECCEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHH
IAADYSVVSILDHPRNHNYPSRAGAASLCVADESMDAYRRFRAALYSRSFQPSELASSFP
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHCC
ENAKLIEIAREAGVVGKVPDCINSGKYLAKVTAEAALAKISATPTIKINGDEYDPLTPEA
CCCHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHH
LVAKIKAIVGAVPGIDVAVTATTT
HHHHHHHHHHCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]