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The map label for this gene is ftsY

Identifier: 221230334

GI number: 221230334

Start: 1953374

End: 1954666

Strand: Reverse

Name: ftsY

Synonym: MLBr_01628

Alternate gene names: 221230334

Gene position: 1954666-1953374 (Counterclockwise)

Preceding gene: 221230335

Following gene: 221230331

Centisome position: 59.81

GC content: 61.72

Gene sequence:

>1293_bases
GTGTCAGAAGGTTTGTGGATCGCCACCGCTGTCGCCGCCGTCCTGGTTGTCATCGCAGCCTTGATTCTGGGCTCGGTGCG
TTACCGTCGGCGGCGGATTAGCTTGATCTTTTCCTCTTTGAGCTCTGGGCCAAGTGCAAGCGACCGTTCCGGCAGCTACA
CTGCGTCGTCGGGTATCACATTCAGCCAAACCGCACTGCCCGTTCAGCCCGCGGACCGGATTGACACCGGAGAACTGCCG
GCGGTGGGCGATGACGCGACCGTGCCTCGTGACTCGCCGCGACACACGATCTCGGACGTATTGCTTCCCGAATCTGAGCT
CATTACGTCACCTGACGAGCCAGAGGCGGCGGTCCCGCACATTGATGCCATTGTTCCACCCGAAGGCCGATTGGATCGGC
TGCGCGGGCGACTCGCCAGGACACAAAATGCGTTCGGACGCAGCATCTTGGGCTTGATCGTCGGCGGCGATCTGGATGAG
GACTCCTGGCAGGAGCTCGAGGATACCTTGCTGGTCGCTGATCTGGGCCCCGTTGCCACTGAGTCGGTGATGTCTGCGTT
GCGCAGCAGGCTGCTCAACAGCAACGTGCATACCGAGAGTGACGCCCGTACCATGCTGCGTGACGTATTGATCAGTGAAC
TGCAACCCGATATGGACCGCTCGATTCGAGCTCTACCGCACGCTGACCATCCGGCAGTGCTGCTGATCGTCGGTGTCAAC
GGCACCGGCAAGACCACCACGGTCGGCAAGTTGGCGCGGGTTTTGGTAGCCGACGGCCGGCGCGTTGTCCTCGGCGCGGC
GGACACGTTTCGGGCAGCGGCCGCCGACCAACTGCAAACCTGGGCTTCTCGGGTGGGTGCAGAGCTGGTGCGTGGTGTCG
AAGGCGCTGACCCGGCATCAGTGGCGTTCGACGCCGTCGACAAAGGCATCGGTGCGGGCGCTGATGTTGTGGTCATCGAC
ACCGCCGGGCGATTGCATACCAAGGTGGGGCTGATGGACGAGCTCGACAAAATCAAGCGTGTGGTGACTCGACGCGCGGC
AGTTGACGAGGTGTTACTGGTACTTGATGCCACCATCGGTCAGAATGGGCTGACGCAAGTTCGGGTCTTCGCCGAGGTTG
TCGACATCACTGGTGCCGTGCTGACCAAGCTAGATGGAACGGCCAAGGGCGGCATTGTTTTTCGTATCCAACGTGAGCTT
GGAGTGCCGGTGAAGCTGGTCGGGCTGGGTGAAGGTCCCGACGACTTGGCGCCATTCGAACCCGCCGTTTTCGTCGATGC
CCTGTTGGAGTGA

Upstream 100 bases:

>100_bases
GGGGGTATCTCCAGCGGTGAGGGGGCGAACTGGGTAATCCAGTTTTAGTCCGGTCCGCCCTCACTGTTCGCCGGGTGTCA
CCCCCTGAAACAATGGCAAC

Downstream 100 bases:

>100_bases
AACTCTTCAGCCGCAGGCTACGTTAATCCCGTTAAACATGGCGGCCTCATCGCAGCAACAACCATTGCACATGGTTCTGG
ATCAGGTTGTTAGGCCAGTC

Product: putative SRP family of GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MSEGLWIATAVAAVLVVIAALILGSVRYRRRRISLIFSSLSSGPSASDRSGSYTASSGITFSQTALPVQPADRIDTGELP
AVGDDATVPRDSPRHTISDVLLPESELITSPDEPEAAVPHIDAIVPPEGRLDRLRGRLARTQNAFGRSILGLIVGGDLDE
DSWQELEDTLLVADLGPVATESVMSALRSRLLNSNVHTESDARTMLRDVLISELQPDMDRSIRALPHADHPAVLLIVGVN
GTGKTTTVGKLARVLVADGRRVVLGAADTFRAAAADQLQTWASRVGAELVRGVEGADPASVAFDAVDKGIGAGADVVVID
TAGRLHTKVGLMDELDKIKRVVTRRAAVDEVLLVLDATIGQNGLTQVRVFAEVVDITGAVLTKLDGTAKGGIVFRIQREL
GVPVKLVGLGEGPDDLAPFEPAVFVDALLE

Sequences:

>Translated_430_residues
MSEGLWIATAVAAVLVVIAALILGSVRYRRRRISLIFSSLSSGPSASDRSGSYTASSGITFSQTALPVQPADRIDTGELP
AVGDDATVPRDSPRHTISDVLLPESELITSPDEPEAAVPHIDAIVPPEGRLDRLRGRLARTQNAFGRSILGLIVGGDLDE
DSWQELEDTLLVADLGPVATESVMSALRSRLLNSNVHTESDARTMLRDVLISELQPDMDRSIRALPHADHPAVLLIVGVN
GTGKTTTVGKLARVLVADGRRVVLGAADTFRAAAADQLQTWASRVGAELVRGVEGADPASVAFDAVDKGIGAGADVVVID
TAGRLHTKVGLMDELDKIKRVVTRRAAVDEVLLVLDATIGQNGLTQVRVFAEVVDITGAVLTKLDGTAKGGIVFRIQREL
GVPVKLVGLGEGPDDLAPFEPAVFVDALLE
>Mature_429_residues
SEGLWIATAVAAVLVVIAALILGSVRYRRRRISLIFSSLSSGPSASDRSGSYTASSGITFSQTALPVQPADRIDTGELPA
VGDDATVPRDSPRHTISDVLLPESELITSPDEPEAAVPHIDAIVPPEGRLDRLRGRLARTQNAFGRSILGLIVGGDLDED
SWQELEDTLLVADLGPVATESVMSALRSRLLNSNVHTESDARTMLRDVLISELQPDMDRSIRALPHADHPAVLLIVGVNG
TGKTTTVGKLARVLVADGRRVVLGAADTFRAAAADQLQTWASRVGAELVRGVEGADPASVAFDAVDKGIGAGADVVVIDT
AGRLHTKVGLMDELDKIKRVVTRRAAVDEVLLVLDATIGQNGLTQVRVFAEVVDITGAVLTKLDGTAKGGIVFRIQRELG
VPVKLVGLGEGPDDLAPFEPAVFVDALLE

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the membrane

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family

Homologues:

Organism=Homo sapiens, GI4507215, Length=267, Percent_Identity=29.9625468164794, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI226371618, Length=230, Percent_Identity=32.1739130434783, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI23308697, Length=288, Percent_Identity=30.5555555555556, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI295424842, Length=288, Percent_Identity=30.5555555555556, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI89061728, Length=133, Percent_Identity=31.5789473684211, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789874, Length=311, Percent_Identity=41.4790996784566, Blast_Score=215, Evalue=6e-57,
Organism=Escherichia coli, GI1788963, Length=296, Percent_Identity=33.1081081081081, Blast_Score=137, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17539958, Length=231, Percent_Identity=33.3333333333333, Blast_Score=130, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI193206261, Length=272, Percent_Identity=31.9852941176471, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6325345, Length=268, Percent_Identity=30.9701492537313, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320498, Length=309, Percent_Identity=24.9190938511327, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17647949, Length=230, Percent_Identity=33.9130434782609, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24641198, Length=315, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSY_MYCLE (O33010)

Other databases:

- EMBL:   Z97369
- EMBL:   AL583922
- PIR:   F87112
- RefSeq:   NP_302120.1
- ProteinModelPortal:   O33010
- EnsemblBacteria:   EBMYCT00000028080
- GeneID:   910809
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML1628
- NMPDR:   fig|272631.1.peg.992
- Leproma:   ML1628
- GeneTree:   EBGT00050000014984
- HOGENOM:   HBG562580
- OMA:   YQQLKVE
- ProtClustDB:   PRK10416
- BioCyc:   MLEP272631:ML1628-MONOMER
- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- Gene3D:   G3DSA:1.20.120.140
- SMART:   SM00382
- SMART:   SM00962
- SMART:   SM00963
- TIGRFAMs:   TIGR00064

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; SSF47364 SRP54

EC number: NA

Molecular weight: Translated: 45355; Mature: 45224

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEGLWIATAVAAVLVVIAALILGSVRYRRRRISLIFSSLSSGPSASDRSGSYTASSGIT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCE
FSQTALPVQPADRIDTGELPAVGDDATVPRDSPRHTISDVLLPESELITSPDEPEAAVPH
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHCCCCCCCCCCCCC
IDAIVPPEGRLDRLRGRLARTQNAFGRSILGLIVGGDLDEDSWQELEDTLLVADLGPVAT
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHEEEEECCCCHHH
ESVMSALRSRLLNSNVHTESDARTMLRDVLISELQPDMDRSIRALPHADHPAVLLIVGVN
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEEEECC
GTGKTTTVGKLARVLVADGRRVVLGAADTFRAAAADQLQTWASRVGAELVRGVEGADPAS
CCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VAFDAVDKGIGAGADVVVIDTAGRLHTKVGLMDELDKIKRVVTRRAAVDEVLLVLDATIG
HHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QNGLTQVRVFAEVVDITGAVLTKLDGTAKGGIVFRIQRELGVPVKLVGLGEGPDDLAPFE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHCCCEEEEECCCCCCCCCCCC
PAVFVDALLE
HHHHHHHHCC
>Mature Secondary Structure 
SEGLWIATAVAAVLVVIAALILGSVRYRRRRISLIFSSLSSGPSASDRSGSYTASSGIT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCE
FSQTALPVQPADRIDTGELPAVGDDATVPRDSPRHTISDVLLPESELITSPDEPEAAVPH
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHCCCCCCCCCCCCC
IDAIVPPEGRLDRLRGRLARTQNAFGRSILGLIVGGDLDEDSWQELEDTLLVADLGPVAT
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHEEEEECCCCHHH
ESVMSALRSRLLNSNVHTESDARTMLRDVLISELQPDMDRSIRALPHADHPAVLLIVGVN
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEEEECC
GTGKTTTVGKLARVLVADGRRVVLGAADTFRAAAADQLQTWASRVGAELVRGVEGADPAS
CCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VAFDAVDKGIGAGADVVVIDTAGRLHTKVGLMDELDKIKRVVTRRAAVDEVLLVLDATIG
HHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QNGLTQVRVFAEVVDITGAVLTKLDGTAKGGIVFRIQRELGVPVKLVGLGEGPDDLAPFE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHCCCEEEEECCCCCCCCCCCC
PAVFVDALLE
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002