| Definition | Mycobacterium leprae Br4923 chromosome, complete genome. |
|---|---|
| Accession | NC_011896 |
| Length | 3,268,071 |
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The map label for this gene is rng [H]
Identifier: 221230247
GI number: 221230247
Start: 1764970
End: 1767744
Strand: Reverse
Name: rng [H]
Synonym: MLBr_01468
Alternate gene names: 221230247
Gene position: 1767744-1764970 (Counterclockwise)
Preceding gene: 221230248
Following gene: 221230246
Centisome position: 54.09
GC content: 61.23
Gene sequence:
>2775_bases GTGATAGACGGTGCACCCCCGTTAGAGCCATCAAAAGAGCCGACGCAGCATATGGAACTGCCGGACCGCTTGAGAGTCCA TTCGCTAGCACGAACGTTGGGAACCACCAGCAGACGAGTGTTGGACGTGCTGAGCGCTCTCGACGGCCGGATCCGTAGCG CACATTCCAGTGTCGACCGCGTCGACGCGGTCCGGGTCCGTGATCTGCTGGCCAGCCAACCCAACTCACCTCATGAACTC ACTGCCGTACCTGATAACCCTGTCGCGCTCGAAGAGCGCGACTCTCGGCTGGTGCTAGAAACCACAGTAGAGCGGCCGCA CTACATGCCGTTGTTCGTTGCGCCACAGCCGATAGAGGTCGATGATGACTCCTGCGCTGACGATGATGTGGAATCCGGTG ACGACTCCGACGTTGGCGACGACGAAGAGCAACCCGATCGACCGGCGAACCGTCGTCGGCGTCGTGGCCGTCGGGGTCGT GGTCGGGGCCGCGGTGAGCAGGGTGGATCCGACGTCCAGAGCGACGATGTCGACGGCGCGGTCGACTCAACCGAGTCTGA GGACTTCGATGGCCAAGATTTCGACGAGTCCGAAGACACCGAAATCGGTTACGACGAGAGTGGGTCCTCTGAAGCCGGCA ACCGCCGCCGCCGTCGGCGCCGACGTCGTAAGTCGGGGGTAGGTGAAGACGAGGGGTGCGCGCCCGACGATCCGCCGAAC ACGGTTGTGCACGAACGGACACCCCGTGCGGCTGGTCGGTCTGCTAGTTTTGACAACGGCGTCAACGGCACGGGCAGCGC CGATATCAAGGGTATCGACGGTTCGACTCGACTGGAGGCCAAGCGGCAACGCCGCCGAGACGGGCGCGACGCCGGGCGGC GCCGTTCATCAGTGTTGAGCGAGGCCGAATTCCTGGCTCGGCGCGAGTCCGTCGAGCGGGTCATGGTGGTGCGCGATCGG ATCCGCACTGAGCCGCCCCACCCTGGCGCTCGATACACCCAGATCGCGGTGCTCGAAGACGGCATCGTCGTCGAGCACTT CGTGACGTCGGCAGCATCTGCTTCCCTGGTCGGCAACATCTACCTCGGTATCGTGCAGAACGTGCTGCCGTCGATGGAGG CGGCCTTCGTTGACATCGGTCGCGGTCGCAACGGCGTGCTTTATGCCGGAGAAGTAAACTGGGAAGCGGCCGGATTGGGC GGGGCCGATCGCAAGATTGAACAGGCCCTCAAACCCGGCGACTATATCGTTGTCCAGGTCAACAAGGACCCGGTCGGGCA CAAAGGGGCGCGACTTACCACGCAAGTGTCTTTGGCCGGTCGTTACCTGGTTTACGTCCCAGGGGCGTCGTCGACCGGGA TCAGCCGTAAGCTGCCTGACACCGAACGCCAGCGCCTCAAGGAGATCCTGCGTGAGGTAGTGCCACCCGATGCGGGCGTG ATCATCCGCACTGCGTCAGAGGGCGTCAAAGAGGAAGACATCCGCAAGGATGTCACCCGCCTGCAGGAGCACTGGGAACA GATCGAAGCCAAGACAATCCAGACCAAGGAAAAGGCCGCTGGCGCTGCGGTGGCCCTTTATGAGGAACCGGATGTGTTGG TCAAAGTCATCCGCGACTTGTTCAATGACGACTTCTCGGGCCTCGTCGTCTCCGGCGACGAGGCATGGAATACCATCAAT GAGTATGTGAATTCTGTTGCTCCCGAACTTGTTTCGAAGTTGACAAAGTATGACCCGCCAATCGGTCCGGACGGGCAGCA CGGGCCAGATGTCTTCGCGGTACATCGCATCGACGAGCAATTGGCCAAGGCAATGGACCGGAAAGTGTGGCTGCCATCGG GCGGTACACTGGTGATTGACCGGACTGAGGCGATGACGGTGATCGACGTCAATACTGGCAAGTTCACCGGGTCTGGGGGT AACCTCGAGCAGACAGTCACCAAGAATAATCTTGAGGCAGCTGAGGAGATCGTGCGCCAGCTGCGGCTGCGTGATATTGG CGGCATCGTGGTCATCGACTTCATCGATATGGTGCTCGAGTCCAACCGCGACTTGGTGTTGCGTCGACTGACTGAGGTGC TTGCTCGCGACCGCACTCGTCACCAGGTGTCCGAGGTGACGTCTTTGGGGCTGGTGCAATTGACCCGCAAACGGTTGGGC ACCGGGCTGGTCGAGGCGTTCTCGACATCGTGTCCGAACTGCACAGGTCGCGGTATCCTGCTGCACACCGACCCAGCTAA TTCGACCCCGATGGTTGGACGCAAGTCCGAGTCAGGCGGTCGGCGAAGTAAGCGATCGAAAAAGAACCGATCGGACGAGA CCGCTGTGGTTAAAGTACCGGTGCATGCTCCGGGCGAGCATCCGATGTTTAAGGCGATGGCCGCGGGCTCGTCCTCGGTG GTTGTTGGTGGCGAGGACGAATCCAACGAGTCTGGTACAGAACTCACCGGGAAGATCGACGAGCCGCTCGAAGAGCAGGC TGTTGCTGGCCTAGATGATGTTGACCAGGAAGATTTCGACACCGACGAAGAAGACGACCTCGACGATGACGAGGAGCTCG ACGACGAGGAAGACCTTGGCGACGATGACGAGGAACTCGATTTAGACGACGATCTTGACGTTGACGAAGACGAGTCTGAC TCCGAGGCCGACCTCGACAGCGCTGACGTGCTTGACCGCTCCACTCTCCTGATCAGAAACAGATCAGGTTTTGCCCGTCC GCGACGGCGGCGCGCAGCGGGTCGTCCGGCCGGGCCGCCGATCCACGTGGACTGA
Upstream 100 bases:
>100_bases GTGAGGCCATCACAAGTCCGGGAGAAGTGACCCGGACACATAGCGAAGGCCTTCGTGTGGCCGCGTCGATCGGACGCGCC CGGGGGCTTGAGGAGAATAC
Downstream 100 bases:
>100_bases CCTTGCATCCGATCAAACAGCGGTCAGAGCCTGTTTGACCCTGTAGTCGCTGGTCAACTACCCTTGGGTAGTTGTCGGCA GGAAGGCGATTAAACCTAGC
Product: putative ribonuclease
Products: NA
Alternate protein names: RNase G; Cytoplasmic axial filament protein [H]
Number of amino acids: Translated: 924; Mature: 924
Protein sequence:
>924_residues MIDGAPPLEPSKEPTQHMELPDRLRVHSLARTLGTTSRRVLDVLSALDGRIRSAHSSVDRVDAVRVRDLLASQPNSPHEL TAVPDNPVALEERDSRLVLETTVERPHYMPLFVAPQPIEVDDDSCADDDVESGDDSDVGDDEEQPDRPANRRRRRGRRGR GRGRGEQGGSDVQSDDVDGAVDSTESEDFDGQDFDESEDTEIGYDESGSSEAGNRRRRRRRRRKSGVGEDEGCAPDDPPN TVVHERTPRAAGRSASFDNGVNGTGSADIKGIDGSTRLEAKRQRRRDGRDAGRRRSSVLSEAEFLARRESVERVMVVRDR IRTEPPHPGARYTQIAVLEDGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYAGEVNWEAAGLG GADRKIEQALKPGDYIVVQVNKDPVGHKGARLTTQVSLAGRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPPDAGV IIRTASEGVKEEDIRKDVTRLQEHWEQIEAKTIQTKEKAAGAAVALYEEPDVLVKVIRDLFNDDFSGLVVSGDEAWNTIN EYVNSVAPELVSKLTKYDPPIGPDGQHGPDVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVIDVNTGKFTGSGG NLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRRLTEVLARDRTRHQVSEVTSLGLVQLTRKRLG TGLVEAFSTSCPNCTGRGILLHTDPANSTPMVGRKSESGGRRSKRSKKNRSDETAVVKVPVHAPGEHPMFKAMAAGSSSV VVGGEDESNESGTELTGKIDEPLEEQAVAGLDDVDQEDFDTDEEDDLDDDEELDDEEDLGDDDEELDLDDDLDVDEDESD SEADLDSADVLDRSTLLIRNRSGFARPRRRRAAGRPAGPPIHVD
Sequences:
>Translated_924_residues MIDGAPPLEPSKEPTQHMELPDRLRVHSLARTLGTTSRRVLDVLSALDGRIRSAHSSVDRVDAVRVRDLLASQPNSPHEL TAVPDNPVALEERDSRLVLETTVERPHYMPLFVAPQPIEVDDDSCADDDVESGDDSDVGDDEEQPDRPANRRRRRGRRGR GRGRGEQGGSDVQSDDVDGAVDSTESEDFDGQDFDESEDTEIGYDESGSSEAGNRRRRRRRRRKSGVGEDEGCAPDDPPN TVVHERTPRAAGRSASFDNGVNGTGSADIKGIDGSTRLEAKRQRRRDGRDAGRRRSSVLSEAEFLARRESVERVMVVRDR IRTEPPHPGARYTQIAVLEDGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYAGEVNWEAAGLG GADRKIEQALKPGDYIVVQVNKDPVGHKGARLTTQVSLAGRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPPDAGV IIRTASEGVKEEDIRKDVTRLQEHWEQIEAKTIQTKEKAAGAAVALYEEPDVLVKVIRDLFNDDFSGLVVSGDEAWNTIN EYVNSVAPELVSKLTKYDPPIGPDGQHGPDVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVIDVNTGKFTGSGG NLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRRLTEVLARDRTRHQVSEVTSLGLVQLTRKRLG TGLVEAFSTSCPNCTGRGILLHTDPANSTPMVGRKSESGGRRSKRSKKNRSDETAVVKVPVHAPGEHPMFKAMAAGSSSV VVGGEDESNESGTELTGKIDEPLEEQAVAGLDDVDQEDFDTDEEDDLDDDEELDDEEDLGDDDEELDLDDDLDVDEDESD SEADLDSADVLDRSTLLIRNRSGFARPRRRRAAGRPAGPPIHVD >Mature_924_residues MIDGAPPLEPSKEPTQHMELPDRLRVHSLARTLGTTSRRVLDVLSALDGRIRSAHSSVDRVDAVRVRDLLASQPNSPHEL TAVPDNPVALEERDSRLVLETTVERPHYMPLFVAPQPIEVDDDSCADDDVESGDDSDVGDDEEQPDRPANRRRRRGRRGR GRGRGEQGGSDVQSDDVDGAVDSTESEDFDGQDFDESEDTEIGYDESGSSEAGNRRRRRRRRRKSGVGEDEGCAPDDPPN TVVHERTPRAAGRSASFDNGVNGTGSADIKGIDGSTRLEAKRQRRRDGRDAGRRRSSVLSEAEFLARRESVERVMVVRDR IRTEPPHPGARYTQIAVLEDGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYAGEVNWEAAGLG GADRKIEQALKPGDYIVVQVNKDPVGHKGARLTTQVSLAGRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPPDAGV IIRTASEGVKEEDIRKDVTRLQEHWEQIEAKTIQTKEKAAGAAVALYEEPDVLVKVIRDLFNDDFSGLVVSGDEAWNTIN EYVNSVAPELVSKLTKYDPPIGPDGQHGPDVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVIDVNTGKFTGSGG NLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRRLTEVLARDRTRHQVSEVTSLGLVQLTRKRLG TGLVEAFSTSCPNCTGRGILLHTDPANSTPMVGRKSESGGRRSKRSKKNRSDETAVVKVPVHAPGEHPMFKAMAAGSSSV VVGGEDESNESGTELTGKIDEPLEEQAVAGLDDVDQEDFDTDEEDDLDDDEELDDEEDLGDDDEELDLDDDLDVDEDESD SEADLDSADVLDRSTLLIRNRSGFARPRRRRAAGRPAGPPIHVD
Specific function: Involved in the processing of the 5'-end of 16S rRNA. Could be involved in chromosome segregation and cell division. It may be one of the components of the cytoplasmic axial filaments bundles or merely regulate the formation of this structure [H]
COG id: COG1530
COG function: function code J; Ribonucleases G and E
Gene ontology:
Cell location: Cytoplasm, cytoskeleton [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 S1 motif domain [H]
Homologues:
Organism=Escherichia coli, GI87082235, Length=415, Percent_Identity=38.3132530120482, Blast_Score=257, Evalue=3e-69, Organism=Escherichia coli, GI1787325, Length=389, Percent_Identity=37.0179948586118, Blast_Score=249, Evalue=5e-67,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012340 - InterPro: IPR016027 - InterPro: IPR003029 - InterPro: IPR019307 - InterPro: IPR022967 - InterPro: IPR004659 [H]
Pfam domain/function: PF10150 RNase_E_G; PF00575 S1 [H]
EC number: 3.1.4.- [C]
Molecular weight: Translated: 101260; Mature: 101260
Theoretical pI: Translated: 4.52; Mature: 4.52
Prosite motif: PS50126 S1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 1.6 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 1.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIDGAPPLEPSKEPTQHMELPDRLRVHSLARTLGTTSRRVLDVLSALDGRIRSAHSSVDR CCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH VDAVRVRDLLASQPNSPHELTAVPDNPVALEERDSRLVLETTVERPHYMPLFVAPQPIEV HHHHHHHHHHHCCCCCCCEEEECCCCCCEECCCCCEEEEEECCCCCCCCEEEECCCCCCC DDDSCADDDVESGDDSDVGDDEEQPDRPANRRRRRGRRGRGRGRGEQGGSDVQSDDVDGA CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC VDSTESEDFDGQDFDESEDTEIGYDESGSSEAGNRRRRRRRRRKSGVGEDEGCAPDDPPN CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC TVVHERTPRAAGRSASFDNGVNGTGSADIKGIDGSTRLEAKRQRRRDGRDAGRRRSSVLS CCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHH EAEFLARRESVERVMVVRDRIRTEPPHPGARYTQIAVLEDGIVVEHFVTSAASASLVGNI HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH YLGIVQNVLPSMEAAFVDIGRGRNGVLYAGEVNWEAAGLGGADRKIEQALKPGDYIVVQV HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEECCCCCHHHHHHHHCCCCCEEEEEE NKDPVGHKGARLTTQVSLAGRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPPDAGV CCCCCCCCCCEEEEEEEECCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCE IIRTASEGVKEEDIRKDVTRLQEHWEQIEAKTIQTKEKAAGAAVALYEEPDVLVKVIRDL EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHH FNDDFSGLVVSGDEAWNTINEYVNSVAPELVSKLTKYDPPIGPDGQHGPDVFAVHRIDEQ HCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHH LAKAMDRKVWLPSGGTLVIDRTEAMTVIDVNTGKFTGSGGNLEQTVTKNNLEAAEEIVRQ HHHHHCCEEECCCCCEEEEECCCEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHH LRLRDIGGIVVIDFIDMVLESNRDLVLRRLTEVLARDRTRHQVSEVTSLGLVQLTRKRLG HHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH TGLVEAFSTSCPNCTGRGILLHTDPANSTPMVGRKSESGGRRSKRSKKNRSDETAVVKVP HHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEE VHAPGEHPMFKAMAAGSSSVVVGGEDESNESGTELTGKIDEPLEEQAVAGLDDVDQEDFD CCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCEECCCCCCCHHHHHHCCCCCCCCCCCC TDEEDDLDDDEELDDEEDLGDDDEELDLDDDLDVDEDESDSEADLDSADVLDRSTLLIRN CCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEC RSGFARPRRRRAAGRPAGPPIHVD CCCCCCHHHHHHCCCCCCCCCCCC >Mature Secondary Structure MIDGAPPLEPSKEPTQHMELPDRLRVHSLARTLGTTSRRVLDVLSALDGRIRSAHSSVDR CCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH VDAVRVRDLLASQPNSPHELTAVPDNPVALEERDSRLVLETTVERPHYMPLFVAPQPIEV HHHHHHHHHHHCCCCCCCEEEECCCCCCEECCCCCEEEEEECCCCCCCCEEEECCCCCCC DDDSCADDDVESGDDSDVGDDEEQPDRPANRRRRRGRRGRGRGRGEQGGSDVQSDDVDGA CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC VDSTESEDFDGQDFDESEDTEIGYDESGSSEAGNRRRRRRRRRKSGVGEDEGCAPDDPPN CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC TVVHERTPRAAGRSASFDNGVNGTGSADIKGIDGSTRLEAKRQRRRDGRDAGRRRSSVLS CCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHH EAEFLARRESVERVMVVRDRIRTEPPHPGARYTQIAVLEDGIVVEHFVTSAASASLVGNI HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH YLGIVQNVLPSMEAAFVDIGRGRNGVLYAGEVNWEAAGLGGADRKIEQALKPGDYIVVQV HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEECCCCCHHHHHHHHCCCCCEEEEEE NKDPVGHKGARLTTQVSLAGRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPPDAGV CCCCCCCCCCEEEEEEEECCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCE IIRTASEGVKEEDIRKDVTRLQEHWEQIEAKTIQTKEKAAGAAVALYEEPDVLVKVIRDL EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHH FNDDFSGLVVSGDEAWNTINEYVNSVAPELVSKLTKYDPPIGPDGQHGPDVFAVHRIDEQ HCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHH LAKAMDRKVWLPSGGTLVIDRTEAMTVIDVNTGKFTGSGGNLEQTVTKNNLEAAEEIVRQ HHHHHCCEEECCCCCEEEEECCCEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHH LRLRDIGGIVVIDFIDMVLESNRDLVLRRLTEVLARDRTRHQVSEVTSLGLVQLTRKRLG HHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH TGLVEAFSTSCPNCTGRGILLHTDPANSTPMVGRKSESGGRRSKRSKKNRSDETAVVKVP HHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEE VHAPGEHPMFKAMAAGSSSVVVGGEDESNESGTELTGKIDEPLEEQAVAGLDDVDQEDFD CCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCEECCCCCCCHHHHHHCCCCCCCCCCCC TDEEDDLDDDEELDDEEDLGDDDEELDLDDDLDVDEDESDSEADLDSADVLDRSTLLIRN CCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEC RSGFARPRRRRAAGRPAGPPIHVD CCCCCCHHHHHHCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]