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The map label for this gene is sigC [H]

Identifier: 221230237

GI number: 221230237

Start: 1740837

End: 1741391

Strand: Direct

Name: sigC [H]

Synonym: MLBr_01448

Alternate gene names: 221230237

Gene position: 1740837-1741391 (Clockwise)

Preceding gene: 221230234

Following gene: 221230253

Centisome position: 53.27

GC content: 63.96

Gene sequence:

>555_bases
ATGATCGCGTCTAGCGGCGACGAGGCCGTTACTGACCTCGCCTTAGCAGCTGCACGCGGGAGCAAACGAGCACTGGAGGC
GTTTATCAAAGCCACCCAGCAAGATGTGTGGCGGTTCGTCGCCTACTTGTCGGATGTGGGCAATGCCGACGATTTGACTC
AGGAGACGTTCCTGCGAGCAATTGGAGCCATCGAGCGGTTTTCCGGACATTCCAGCGGCCGAACCTGGCTGCTGGCCATT
GCGCGCCGGGTGGTCGCCGACCACATCCGCCGGGCCCAAACACGACCCCGCACCACCTTCGACGGCTACCCCGAACGCAT
GCTCAACGCCGACCGCCACGCCCGCGGATTCGAAGACCTCGTTGAAGTGACAACAATGATCGCCAACCTTGCCACCGAAC
AACGCGAAGCCCTGTTGCTCACTCAGCTTCTCGGGCTGCCCTACGCCGATGCCGCCGCGGTGTGCGGTTGCCCGGTGGGG
ACCATTCGATCCCGGGTCGCCCGTGCCCGGGACGCGCTGTTGGCCGACACCGAGCATAACCACCTGACCGGGTAG

Upstream 100 bases:

>100_bases
CAACGCACCTGCTGCACGAAATCAATCAGTGCGGCCATCAATCAGTCTACGACAATTGGTCGTAGACTGATTGATGGCCG
CACATTTAAAGTGGATCCCT

Downstream 100 bases:

>100_bases
AAATTTAGCACACAGCAAGGCGATTTCCCAGGCAACGGCATTGCTGAGTGCAATGACGACCCAAAACGTCGCTCCGTGCC
TTATTACTCTTTGTCCTTGC

Product: RNA polymerase sigma factor SigC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MIASSGDEAVTDLALAAARGSKRALEAFIKATQQDVWRFVAYLSDVGNADDLTQETFLRAIGAIERFSGHSSGRTWLLAI
ARRVVADHIRRAQTRPRTTFDGYPERMLNADRHARGFEDLVEVTTMIANLATEQREALLLTQLLGLPYADAAAVCGCPVG
TIRSRVARARDALLADTEHNHLTG

Sequences:

>Translated_184_residues
MIASSGDEAVTDLALAAARGSKRALEAFIKATQQDVWRFVAYLSDVGNADDLTQETFLRAIGAIERFSGHSSGRTWLLAI
ARRVVADHIRRAQTRPRTTFDGYPERMLNADRHARGFEDLVEVTTMIANLATEQREALLLTQLLGLPYADAAAVCGCPVG
TIRSRVARARDALLADTEHNHLTG
>Mature_184_residues
MIASSGDEAVTDLALAAARGSKRALEAFIKATQQDVWRFVAYLSDVGNADDLTQETFLRAIGAIERFSGHSSGRTWLLAI
ARRVVADHIRRAQTRPRTTFDGYPERMLNADRHARGFEDLVEVTTMIANLATEQREALLLTQLLGLPYADAAAVCGCPVG
TIRSRVARARDALLADTEHNHLTG

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=179, Percent_Identity=30.1675977653631, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 20119; Mature: 20119

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIASSGDEAVTDLALAAARGSKRALEAFIKATQQDVWRFVAYLSDVGNADDLTQETFLRA
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
IGAIERFSGHSSGRTWLLAIARRVVADHIRRAQTRPRTTFDGYPERMLNADRHARGFEDL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHCCCHHHH
VEVTTMIANLATEQREALLLTQLLGLPYADAAAVCGCPVGTIRSRVARARDALLADTEHN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
HLTG
CCCC
>Mature Secondary Structure
MIASSGDEAVTDLALAAARGSKRALEAFIKATQQDVWRFVAYLSDVGNADDLTQETFLRA
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
IGAIERFSGHSSGRTWLLAIARRVVADHIRRAQTRPRTTFDGYPERMLNADRHARGFEDL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHCCCHHHH
VEVTTMIANLATEQREALLLTQLLGLPYADAAAVCGCPVGTIRSRVARARDALLADTEHN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
HLTG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]