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The map label for this gene is ideR [H]

Identifier: 221229963

GI number: 221229963

Start: 1183521

End: 1184213

Strand: Reverse

Name: ideR [H]

Synonym: MLBr_01013

Alternate gene names: 221229963

Gene position: 1184213-1183521 (Counterclockwise)

Preceding gene: 221229964

Following gene: 221229962

Centisome position: 36.24

GC content: 60.03

Gene sequence:

>693_bases
ATGAATGACCTGGTTGATACCACCGAGATGTACCTGCGGACCATTTACGACCTCGAGGAAGAGGGTGTCACACCGCTGCG
CGCCCGTATCGCCGAGCGGCTCGAGCAGAGCGGGCCTACAGTGAGCCAAACTGTGTCCCGGATGGAACGGGACGGATTAC
TCCGGGTGGCTGGCAACCGTCATCTAGAGCTCACGACCAAAGGCCGCGCGATGGCCATCGCGGTGATGCGTAAGCACCGT
CTCGCGGAACGACTGCTGGTCGATGTCATCGGGTTGCCGTGGGAAGAGGTTCACGCCGAAGCATGTCGGTGGGAACACGT
AATGAGTGAGGATGTTGAGCGCCGGCTGATTAAAGTACTAAACAACCCGACGACATCACCGTTCGGCAACCCGATTCCAG
GTCTGCTAGACCTCGGTGCTGGACCGGATGCCAGCGCCGCCAACGCCAAACTTGTCCGGTTGACTGAGTTGCCGTCCGGG
TCACCGGTGGCAGTGGTCGTCCGCCAGCTCACCGAACATGTCCAGGACGATATCGATCTGATCACGCGGCTCAAAGACAC
CGGCGTCGTGCCCAACGCACGTGTGACGGTGGAGACAAGCCCAGCGGGCAACGTGATCATCATTATCCCCGGTCACGAAA
ACGTCACTCTGCCGCATGAGATGGCGCACGCGGTCAAAGTCGAGAAGGTCTGA

Upstream 100 bases:

>100_bases
TTATGCCCGCCGCCCCGTGGCGGGCATACTGCTGCCGCGAAGCTCGGCAAACCATCGGCGCAGCTGGCCAAGTAGACTCG
CCAGTAATGGAGGGTGCTGA

Downstream 100 bases:

>100_bases
TTCATTCGTTCGGGCCGATGCGGCTCGAACGGCCGGACTGAGACCTAACCCGCCGCGCTGGCCAAATGTCCAGAGCGGCG
GTAGCCAAATACCGAGTCAT

Product: iron dependent repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MNDLVDTTEMYLRTIYDLEEEGVTPLRARIAERLEQSGPTVSQTVSRMERDGLLRVAGNRHLELTTKGRAMAIAVMRKHR
LAERLLVDVIGLPWEEVHAEACRWEHVMSEDVERRLIKVLNNPTTSPFGNPIPGLLDLGAGPDASAANAKLVRLTELPSG
SPVAVVVRQLTEHVQDDIDLITRLKDTGVVPNARVTVETSPAGNVIIIIPGHENVTLPHEMAHAVKVEKV

Sequences:

>Translated_230_residues
MNDLVDTTEMYLRTIYDLEEEGVTPLRARIAERLEQSGPTVSQTVSRMERDGLLRVAGNRHLELTTKGRAMAIAVMRKHR
LAERLLVDVIGLPWEEVHAEACRWEHVMSEDVERRLIKVLNNPTTSPFGNPIPGLLDLGAGPDASAANAKLVRLTELPSG
SPVAVVVRQLTEHVQDDIDLITRLKDTGVVPNARVTVETSPAGNVIIIIPGHENVTLPHEMAHAVKVEKV
>Mature_230_residues
MNDLVDTTEMYLRTIYDLEEEGVTPLRARIAERLEQSGPTVSQTVSRMERDGLLRVAGNRHLELTTKGRAMAIAVMRKHR
LAERLLVDVIGLPWEEVHAEACRWEHVMSEDVERRLIKVLNNPTTSPFGNPIPGLLDLGAGPDASAANAKLVRLTELPSG
SPVAVVVRQLTEHVQDDIDLITRLKDTGVVPNARVTVETSPAGNVIIIIPGHENVTLPHEMAHAVKVEKV

Specific function: Metal-dependent DNA-binding protein that controls transcription of many genes involved in iron metabolism [H]

COG id: COG1321

COG function: function code K; Mn-dependent transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH dtxR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007167
- InterPro:   IPR001367
- InterPro:   IPR022689
- InterPro:   IPR022687
- InterPro:   IPR008988
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02742 Fe_dep_repr_C; PF01325 Fe_dep_repress; PF04023 FeoA [H]

EC number: NA

Molecular weight: Translated: 25355; Mature: 25355

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50944 HTH_DTXR ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLVDTTEMYLRTIYDLEEEGVTPLRARIAERLEQSGPTVSQTVSRMERDGLLRVAGNR
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEECCCC
HLELTTKGRAMAIAVMRKHRLAERLLVDVIGLPWEEVHAEACRWEHVMSEDVERRLIKVL
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NNPTTSPFGNPIPGLLDLGAGPDASAANAKLVRLTELPSGSPVAVVVRQLTEHVQDDIDL
CCCCCCCCCCCCCCCEECCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
ITRLKDTGVVPNARVTVETSPAGNVIIIIPGHENVTLPHEMAHAVKVEKV
HHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MNDLVDTTEMYLRTIYDLEEEGVTPLRARIAERLEQSGPTVSQTVSRMERDGLLRVAGNR
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEECCCC
HLELTTKGRAMAIAVMRKHRLAERLLVDVIGLPWEEVHAEACRWEHVMSEDVERRLIKVL
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NNPTTSPFGNPIPGLLDLGAGPDASAANAKLVRLTELPSGSPVAVVVRQLTEHVQDDIDL
CCCCCCCCCCCCCCCEECCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
ITRLKDTGVVPNARVTVETSPAGNVIIIIPGHENVTLPHEMAHAVKVEKV
HHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]