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The map label for this gene is ctaC

Identifier: 221229875

GI number: 221229875

Start: 1039825

End: 1040886

Strand: Direct

Name: ctaC

Synonym: MLBr_00875

Alternate gene names: 221229875

Gene position: 1039825-1040886 (Clockwise)

Preceding gene: 221229873

Following gene: 221229876

Centisome position: 31.82

GC content: 56.87

Gene sequence:

>1062_bases
GTGACAGCTCGCGAGTTAGTCTGTTCGCAACGTGTCGGTCAGGGTCTCTCTCGTCGTCTTCGGCCGCTGGTGCTGGCCGT
GACACTGGGTGTGCTGGTGGTCACCCTGAGCGGATGCAGCTGGTCGGACGCGTTGGCCATTGGCTGGCCGGAAGGCATCA
CCCCGGAGGCCCACCTCAACCGACAGCTGTGGATCGGTGCGGTGGTCGCCTCCCTGGTCGTCGGTGTCATTGTGTGGGGT
CTCATTTTCTGGTCGACCATCTTCCACCGGAAGAAAACAACCGACACCGAGTTGCCGCGTCAATTCGGCTACAACATGCC
GCTGGAGTTGGTGCTGACCGTGACGCCATTCCTCATCATTTCTATGCTGTTCTATTTCACTGTGATAGTGCAGGATAAGA
TGCTGTACCTCGCCAAGGATCCCGAAGTTGTCATTGATGTTACGGCCTTTCAGTGGAACTGGAAGTTCGGCTATCAGCGG
GTCGATTTCAAAGACGGCACCTTGACCTACGACGGGGTCGATCCGGCCCGCAAAAAGGCCATGGTCTCCAAGCCAGAGGG
CAAGGACTCCCATGGTGAGGAGCTCGTCGGGGCGGTGCGTGGGCTCAATACCGAGGACCGGGCCTACCTGAACTTCGACA
AGGTTGAAACTTTGGGCACTACTACTGAAATTCCGGTGCTTGTGCTGCCCGCTGGCAAGCGCATCGAGTTCCAATTGAAC
TCCGCCGACGTGGTTCACTCGTTTTGGGTGCCGAAATTTTTGTTCAAGCGCGACGTCATGCCCAACCCGGTGGCGAACAA
CTCCGTGAACGTCTTCCAGGTCGAAGAGATAACAAAGACCGGGGCATTCGTCGGCCACTGCGCTGAGATGTGCGGTACAT
ATCACTCGATGATGAACTTCGAAGTTCGAGTTGTCGCTCCTAACGACTTCAAGGCCTATTTGCAACAACGGATCGACGGA
AAAACCAACGCTGAAGCATTGCAGGTGATCGCTCAGCCTCCGCTGGCGGTGACTACCCACCCGTTTGATACCCGTCGCGG
ACAGTTGACCAACAGCCAGTAG

Upstream 100 bases:

>100_bases
CTACGCTGCGTAGTATTAGACATCCGAGTTAGCCGAAGAATCCCGCCTTTAAGCGGGTTAGCTTCGAATCGGCCCAGCTT
GTGATACAGGAGGCGCCAAA

Downstream 100 bases:

>100_bases
GTAGTCCCACTAAGGGTCCAGTAGGTAGTCCCACTAAGGGTTAGGACACGCAATGCATATCGAAGCGAGGCTATTCGAGT
TTGTCGCTGTGTTCTTTGTC

Product: putative cytochrome C oxidase chain II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MTARELVCSQRVGQGLSRRLRPLVLAVTLGVLVVTLSGCSWSDALAIGWPEGITPEAHLNRQLWIGAVVASLVVGVIVWG
LIFWSTIFHRKKTTDTELPRQFGYNMPLELVLTVTPFLIISMLFYFTVIVQDKMLYLAKDPEVVIDVTAFQWNWKFGYQR
VDFKDGTLTYDGVDPARKKAMVSKPEGKDSHGEELVGAVRGLNTEDRAYLNFDKVETLGTTTEIPVLVLPAGKRIEFQLN
SADVVHSFWVPKFLFKRDVMPNPVANNSVNVFQVEEITKTGAFVGHCAEMCGTYHSMMNFEVRVVAPNDFKAYLQQRIDG
KTNAEALQVIAQPPLAVTTHPFDTRRGQLTNSQ

Sequences:

>Translated_353_residues
MTARELVCSQRVGQGLSRRLRPLVLAVTLGVLVVTLSGCSWSDALAIGWPEGITPEAHLNRQLWIGAVVASLVVGVIVWG
LIFWSTIFHRKKTTDTELPRQFGYNMPLELVLTVTPFLIISMLFYFTVIVQDKMLYLAKDPEVVIDVTAFQWNWKFGYQR
VDFKDGTLTYDGVDPARKKAMVSKPEGKDSHGEELVGAVRGLNTEDRAYLNFDKVETLGTTTEIPVLVLPAGKRIEFQLN
SADVVHSFWVPKFLFKRDVMPNPVANNSVNVFQVEEITKTGAFVGHCAEMCGTYHSMMNFEVRVVAPNDFKAYLQQRIDG
KTNAEALQVIAQPPLAVTTHPFDTRRGQLTNSQ
>Mature_352_residues
TARELVCSQRVGQGLSRRLRPLVLAVTLGVLVVTLSGCSWSDALAIGWPEGITPEAHLNRQLWIGAVVASLVVGVIVWGL
IFWSTIFHRKKTTDTELPRQFGYNMPLELVLTVTPFLIISMLFYFTVIVQDKMLYLAKDPEVVIDVTAFQWNWKFGYQRV
DFKDGTLTYDGVDPARKKAMVSKPEGKDSHGEELVGAVRGLNTEDRAYLNFDKVETLGTTTEIPVLVLPAGKRIEFQLNS
ADVVHSFWVPKFLFKRDVMPNPVANNSVNVFQVEEITKTGAFVGHCAEMCGTYHSMMNFEVRVVAPNDFKAYLQQRIDGK
TNAEALQVIAQPPLAVTTHPFDTRRGQLTNSQ

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COX2_MYCLE (Q9CCF1)

Other databases:

- EMBL:   AL583920
- PIR:   E87018
- RefSeq:   NP_301661.1
- ProteinModelPortal:   Q9CCF1
- SMR:   Q9CCF1
- EnsemblBacteria:   EBMYCT00000028222
- GeneID:   909877
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML0875
- NMPDR:   fig|272631.1.peg.533
- Leproma:   ML0875
- GeneTree:   EBGT00050000016956
- HOGENOM:   HBG428789
- OMA:   YQWNWKF
- ProtClustDB:   CLSK791696
- BioCyc:   MLEP272631:ML0875-MONOMER
- BRENDA:   1.9.3.1
- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759
- Gene3D:   G3DSA:1.10.287.90
- Gene3D:   G3DSA:2.60.40.420
- PANTHER:   PTHR22888

Pfam domain/function: PF00116 COX2; SSF49503 Cupredoxin; SSF81464 Cyt_c_oxidase_II-like_TM

EC number: =1.9.3.1

Molecular weight: Translated: 39521; Mature: 39390

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00078 COX2; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x21ca1e20)-; HASH(0x226c91a8)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARELVCSQRVGQGLSRRLRPLVLAVTLGVLVVTLSGCSWSDALAIGWPEGITPEAHLN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHCC
RQLWIGAVVASLVVGVIVWGLIFWSTIFHRKKTTDTELPRQFGYNMPLELVLTVTPFLII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHH
SMLFYFTVIVQDKMLYLAKDPEVVIDVTAFQWNWKFGYQRVDFKDGTLTYDGVDPARKKA
HHHHHHHHHHHHCEEEEECCCCEEEEEEEEEEEEEECCEEEECCCCEEEECCCCHHHHHH
MVSKPEGKDSHGEELVGAVRGLNTEDRAYLNFDKVETLGTTTEIPVLVLPAGKRIEFQLN
HCCCCCCCCCHHHHHHHHHHCCCCCCCEEECHHHHHHCCCCCCCCEEEECCCCEEEEEEC
SADVVHSFWVPKFLFKRDVMPNPVANNSVNVFQVEEITKTGAFVGHCAEMCGTYHSMMNF
CCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCE
EVRVVAPNDFKAYLQQRIDGKTNAEALQVIAQPPLAVTTHPFDTRRGQLTNSQ
EEEEECCCHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCH
>Mature Secondary Structure 
TARELVCSQRVGQGLSRRLRPLVLAVTLGVLVVTLSGCSWSDALAIGWPEGITPEAHLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHCC
RQLWIGAVVASLVVGVIVWGLIFWSTIFHRKKTTDTELPRQFGYNMPLELVLTVTPFLII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHH
SMLFYFTVIVQDKMLYLAKDPEVVIDVTAFQWNWKFGYQRVDFKDGTLTYDGVDPARKKA
HHHHHHHHHHHHCEEEEECCCCEEEEEEEEEEEEEECCEEEECCCCEEEECCCCHHHHHH
MVSKPEGKDSHGEELVGAVRGLNTEDRAYLNFDKVETLGTTTEIPVLVLPAGKRIEFQLN
HCCCCCCCCCHHHHHHHHHHCCCCCCCEEECHHHHHHCCCCCCCCEEEECCCCEEEEEEC
SADVVHSFWVPKFLFKRDVMPNPVANNSVNVFQVEEITKTGAFVGHCAEMCGTYHSMMNF
CCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCE
EVRVVAPNDFKAYLQQRIDGKTNAEALQVIAQPPLAVTTHPFDTRRGQLTNSQ
EEEEECCCHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11234002