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The map label for this gene is yhaU [H]

Identifier: 221229820

GI number: 221229820

Start: 926177

End: 927334

Strand: Direct

Name: yhaU [H]

Synonym: MLBr_00782

Alternate gene names: 221229820

Gene position: 926177-927334 (Clockwise)

Preceding gene: 221229819

Following gene: 221229823

Centisome position: 28.34

GC content: 62.95

Gene sequence:

>1158_bases
ATGGAAATTTCGGGGGCGCTGCTGTCCCAAGTCGGCGCCCTCTTGACCACACTTGCTGTGCTGGGCGCCGGCGCACGCCG
GTACTCTTTGTCTCCGATACCGGTTTATCTAATGGCGGGGCTTTCACTCGGTAAGGGCGGCATCATGCCAGTGTCCGCCG
CTGATGAATTCATCACTACGGGAGCGCCCATTGGCATTGTGTTGTTGCTGCTGACATTGGGTCTGGAGTTCTCTGCGACC
GAGTTCGCCAGCAGTCTGCGGCGTCACCTGCCGTCAGCCGGTGTCGACATCATCCTCAACGCCACGCCCGGCGCAGTGGC
CGGTTGGCTGCTGGGTTTGGACGGGGTCGCCGTGCTCGCGTTGGCCGGCGTCACGTACATTTCCTCATCCGGTGTCATTG
CGCGCTTGCTGGCTGACTTACGTCGGCTCGGTAACCGGGAAACGCCGGCGGTGCTGTCTGTGTTGGTGCTCGAAGACTTT
GCGATGGCGGCCTACTTGCCACTATTCGCGGTACTTGCGGCGGGTGGCAGCTGGCTGGATGCCGTCGTTGGCATGATAGT
CGCGGTCTGTGCGCTATTCGCGGCGTTTGCCGCGTCCTATCACTGGGGCCATCATGTCGGTCGGCTGGTGGCGCATCCCG
ATTCCGAGCAGTTGTTGCTGAGGGTCCTGGGGGTGACTCTGATCGTGGCGGCGGTGGCCGAGTCCTTGCACGCGTCGGCC
GCCGTAGGCGCATTCTTGGTCGGTTTGACCCTGACGGGGGATACCGCGGAACGCGCACGTAAGGTGCTCGGTCCTCTTCG
TGATCTGTTCGCAGCGATTTTCTTCCTTGCTATCGGCATATCGGTCGACCCGCACAAACTCCTGCCGATGTTTCCGACAG
CCCTGATCCTGGCCACTGTCACCGCGGTGACCAAGGTGGCTACCGGAATTCTGGCCGCCCGGTACGACGGCGTGGCACGA
CGCGGGCAGTTGCGCGCTGGTACAGCGCTCGTCGCTCGGGGCGAGTTTTCGTTGATCATCATCGGATTGGTCGGCACGTC
GACCCCCGCCGTGGCCGCGCTGGCCACAGCGTATGTCTTCATCATGGCAATCGCTGGCCCGGTGCTGGCTCGCTACACTC
CTGGTTCGTTGCCGACCAGCTCTGGGTCGGCCAACTAG

Upstream 100 bases:

>100_bases
GGCCCGGCTGAACCGCTGCGGGCACGAGATGTGTTGATCGTGATAGGTACCGAAGAAGGTATCGCCGGGGTCGAGCAGAT
CATCGACAAGGGCTGAGGAG

Downstream 100 bases:

>100_bases
GCAGCTGGTGGCGACTCGCTTCGCTCTGGCTGCGTCGCGCTCGCCACTACTAGAGCTGTTACCTGAGACCGTTCAACCGA
TATGCAAGACAACTACCAGC

Product: putative transmembrane transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MEISGALLSQVGALLTTLAVLGAGARRYSLSPIPVYLMAGLSLGKGGIMPVSAADEFITTGAPIGIVLLLLTLGLEFSAT
EFASSLRRHLPSAGVDIILNATPGAVAGWLLGLDGVAVLALAGVTYISSSGVIARLLADLRRLGNRETPAVLSVLVLEDF
AMAAYLPLFAVLAAGGSWLDAVVGMIVAVCALFAAFAASYHWGHHVGRLVAHPDSEQLLLRVLGVTLIVAAVAESLHASA
AVGAFLVGLTLTGDTAERARKVLGPLRDLFAAIFFLAIGISVDPHKLLPMFPTALILATVTAVTKVATGILAARYDGVAR
RGQLRAGTALVARGEFSLIIIGLVGTSTPAVAALATAYVFIMAIAGPVLARYTPGSLPTSSGSAN

Sequences:

>Translated_385_residues
MEISGALLSQVGALLTTLAVLGAGARRYSLSPIPVYLMAGLSLGKGGIMPVSAADEFITTGAPIGIVLLLLTLGLEFSAT
EFASSLRRHLPSAGVDIILNATPGAVAGWLLGLDGVAVLALAGVTYISSSGVIARLLADLRRLGNRETPAVLSVLVLEDF
AMAAYLPLFAVLAAGGSWLDAVVGMIVAVCALFAAFAASYHWGHHVGRLVAHPDSEQLLLRVLGVTLIVAAVAESLHASA
AVGAFLVGLTLTGDTAERARKVLGPLRDLFAAIFFLAIGISVDPHKLLPMFPTALILATVTAVTKVATGILAARYDGVAR
RGQLRAGTALVARGEFSLIIIGLVGTSTPAVAALATAYVFIMAIAGPVLARYTPGSLPTSSGSAN
>Mature_385_residues
MEISGALLSQVGALLTTLAVLGAGARRYSLSPIPVYLMAGLSLGKGGIMPVSAADEFITTGAPIGIVLLLLTLGLEFSAT
EFASSLRRHLPSAGVDIILNATPGAVAGWLLGLDGVAVLALAGVTYISSSGVIARLLADLRRLGNRETPAVLSVLVLEDF
AMAAYLPLFAVLAAGGSWLDAVVGMIVAVCALFAAFAASYHWGHHVGRLVAHPDSEQLLLRVLGVTLIVAAVAESLHASA
AVGAFLVGLTLTGDTAERARKVLGPLRDLFAAIFFLAIGISVDPHKLLPMFPTALILATVTAVTKVATGILAARYDGVAR
RGQLRAGTALVARGEFSLIIIGLVGTSTPAVAALATAYVFIMAIAGPVLARYTPGSLPTSSGSAN

Specific function: Potassium/proton antiporter that mediates the efflux of potassium ions from the cell. Potassium antiport activity requires the presence of khtT. Has higher activity at alkaline pH. Can also mediate rubidium/proton antiport. Has no permeability for sodium

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 39276; Mature: 39276

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEISGALLSQVGALLTTLAVLGAGARRYSLSPIPVYLMAGLSLGKGGIMPVSAADEFITT
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHC
GAPIGIVLLLLTLGLEFSATEFASSLRRHLPSAGVDIILNATPGAVAGWLLGLDGVAVLA
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
LAGVTYISSSGVIARLLADLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLAAGGSWLD
HHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AVVGMIVAVCALFAAFAASYHWGHHVGRLVAHPDSEQLLLRVLGVTLIVAAVAESLHASA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGAFLVGLTLTGDTAERARKVLGPLRDLFAAIFFLAIGISVDPHKLLPMFPTALILATV
HHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
TAVTKVATGILAARYDGVARRGQLRAGTALVARGEFSLIIIGLVGTSTPAVAALATAYVF
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEEEECCCCHHHHHHHHHHHH
IMAIAGPVLARYTPGSLPTSSGSAN
HHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEISGALLSQVGALLTTLAVLGAGARRYSLSPIPVYLMAGLSLGKGGIMPVSAADEFITT
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHC
GAPIGIVLLLLTLGLEFSATEFASSLRRHLPSAGVDIILNATPGAVAGWLLGLDGVAVLA
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
LAGVTYISSSGVIARLLADLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLAAGGSWLD
HHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AVVGMIVAVCALFAAFAASYHWGHHVGRLVAHPDSEQLLLRVLGVTLIVAAVAESLHASA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGAFLVGLTLTGDTAERARKVLGPLRDLFAAIFFLAIGISVDPHKLLPMFPTALILATV
HHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
TAVTKVATGILAARYDGVARRGQLRAGTALVARGEFSLIIIGLVGTSTPAVAALATAYVF
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEEEECCCCHHHHHHHHHHHH
IMAIAGPVLARYTPGSLPTSSGSAN
HHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]