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The map label for this gene is psaA [H]

Identifier: 221229571

GI number: 221229571

Start: 426572

End: 427480

Strand: Reverse

Name: psaA [H]

Synonym: MLBr_00337

Alternate gene names: 221229571

Gene position: 427480-426572 (Counterclockwise)

Preceding gene: 221229578

Following gene: 221229570

Centisome position: 13.08

GC content: 61.72

Gene sequence:

>909_bases
ATGCGTTGGTTGACGACTATCATTCTGTGCTTGATCAGTTCGACCGTTGCGGGTGGCTGCGGCAGCCTTAGTTCCGGGCA
CCTGCGCCCGACAGCCGTGGTGGCATCCACTGACGTGTGGGGCAGTGTGGCTCGCATTATTGCAGGCAGACACGTCGCCG
TCACCTCCATTGTGACCGGTGCCCACACCGATCCGCACACGTATCGTGTCAATCCCGCTGAAACTGCCGCGATCACCGAC
GCCGCACTAGTGGTCTACAACGGCGGCGGTTACGATCCATGGGTCGACAAGGTGCTGGCCGGCCGTCCGGACATCAAATC
GGTGGATGCTTACTCGCTTCTCGCTAGCAGGGGCGCCACCACCGAAGGACCGGCCGACGAACACGTCTTCTACGACCTGA
ACATCGCCAAGTCGGTGGCCTCCCTGATCGCCGACCAGCTGGTGACCATCGATCCGGACAATGCCGCGGACTACCAGGCC
AACGCCACCGAATTCTGCCGCAGCGCCGACGCTATCGCCATATCCGAACACGCCATTGCCAGCGACTACCCAGCCGCCGG
GGTAATCGTAACCGAGCCCGTGGTGCACTACCTGCTGCAGGCATCCGGCCTGGTCAATCGCACGCCGCCGGCCTTTACCG
CAACCCATGAGAACGAGAACGATCCGTCGGCAGCCGACATGGCGGCCGCCCTCAATCTGATCAACCACCGTCAAGTCTCG
GCGTTGCTGGTAAACCCGCAGAAATCGAACGCCGCTACCAACGGCCTGCAGGCTGCGGCCCGACGGTCAGGTGTGCCAGT
GACCGAAGTGACCGAGATGTTGCCGAACGACACCGATTACCTTACCTGGCAACGTAACACGATCGATCAGCTGCTCACTG
CGCTGCAATCGAACCGATCACCCCGATAA

Upstream 100 bases:

>100_bases
ATTTTCGTTAAGTATTATTTAGCGGTTGGCCGGCCAGCGAGAGGAAAGTCGAGCGTGCGATATAGCCCCGATGGGACACC
CAATGGCATCCGTTAATCCG

Downstream 100 bases:

>100_bases
TCTTTGCCGTGGCGGTTGAAAATCTCGACGCGGTCTCGAGACGACCGCAGTCCGCGGACAACGATGCCCGCACGATCTCG
CTTAGCGGCGCACGGCTGGC

Product: putative periplasmic solute-binding proteins

Products: NA

Alternate protein names: Pneumococcal surface adhesin A [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MRWLTTIILCLISSTVAGGCGSLSSGHLRPTAVVASTDVWGSVARIIAGRHVAVTSIVTGAHTDPHTYRVNPAETAAITD
AALVVYNGGGYDPWVDKVLAGRPDIKSVDAYSLLASRGATTEGPADEHVFYDLNIAKSVASLIADQLVTIDPDNAADYQA
NATEFCRSADAIAISEHAIASDYPAAGVIVTEPVVHYLLQASGLVNRTPPAFTATHENENDPSAADMAAALNLINHRQVS
ALLVNPQKSNAATNGLQAAARRSGVPVTEVTEMLPNDTDYLTWQRNTIDQLLTALQSNRSPR

Sequences:

>Translated_302_residues
MRWLTTIILCLISSTVAGGCGSLSSGHLRPTAVVASTDVWGSVARIIAGRHVAVTSIVTGAHTDPHTYRVNPAETAAITD
AALVVYNGGGYDPWVDKVLAGRPDIKSVDAYSLLASRGATTEGPADEHVFYDLNIAKSVASLIADQLVTIDPDNAADYQA
NATEFCRSADAIAISEHAIASDYPAAGVIVTEPVVHYLLQASGLVNRTPPAFTATHENENDPSAADMAAALNLINHRQVS
ALLVNPQKSNAATNGLQAAARRSGVPVTEVTEMLPNDTDYLTWQRNTIDQLLTALQSNRSPR
>Mature_302_residues
MRWLTTIILCLISSTVAGGCGSLSSGHLRPTAVVASTDVWGSVARIIAGRHVAVTSIVTGAHTDPHTYRVNPAETAAITD
AALVVYNGGGYDPWVDKVLAGRPDIKSVDAYSLLASRGATTEGPADEHVFYDLNIAKSVASLIADQLVTIDPDNAADYQA
NATEFCRSADAIAISEHAIASDYPAAGVIVTEPVVHYLLQASGLVNRTPPAFTATHENENDPSAADMAAALNLINHRQVS
ALLVNPQKSNAATNGLQAAARRSGVPVTEVTEMLPNDTDYLTWQRNTIDQLLTALQSNRSPR

Specific function: Part of an ATP-driven transport system for manganese. Also act as an adhesin which is involved on adherence to extracellular matrix. It is an important factor in pathogenesis and infection [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 31892; Mature: 31892

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWLTTIILCLISSTVAGGCGSLSSGHLRPTAVVASTDVWGSVARIIAGRHVAVTSIVTG
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCEEEHHHHHC
AHTDPHTYRVNPAETAAITDAALVVYNGGGYDPWVDKVLAGRPDIKSVDAYSLLASRGAT
CCCCCCEEEECCHHHHHCCEEEEEEECCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCC
TEGPADEHVFYDLNIAKSVASLIADQLVTIDPDNAADYQANATEFCRSADAIAISEHAIA
CCCCCCCEEEEEHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHCCCCEEECCHHHC
SDYPAAGVIVTEPVVHYLLQASGLVNRTPPAFTATHENENDPSAADMAAALNLINHRQVS
CCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHEEE
ALLVNPQKSNAATNGLQAAARRSGVPVTEVTEMLPNDTDYLTWQRNTIDQLLTALQSNRS
EEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCC
PR
CC
>Mature Secondary Structure
MRWLTTIILCLISSTVAGGCGSLSSGHLRPTAVVASTDVWGSVARIIAGRHVAVTSIVTG
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCEEEHHHHHC
AHTDPHTYRVNPAETAAITDAALVVYNGGGYDPWVDKVLAGRPDIKSVDAYSLLASRGAT
CCCCCCEEEECCHHHHHCCEEEEEEECCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCC
TEGPADEHVFYDLNIAKSVASLIADQLVTIDPDNAADYQANATEFCRSADAIAISEHAIA
CCCCCCCEEEEEHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHCCCCEEECCHHHC
SDYPAAGVIVTEPVVHYLLQASGLVNRTPPAFTATHENENDPSAADMAAALNLINHRQVS
CCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHEEE
ALLVNPQKSNAATNGLQAAARRSGVPVTEVTEMLPNDTDYLTWQRNTIDQLLTALQSNRS
EEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCC
PR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8945574; 9767595; 11463916; 9379902 [H]