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The map label for this gene is moaB [H]

Identifier: 221229468

GI number: 221229468

Start: 244240

End: 244785

Strand: Direct

Name: moaB [H]

Synonym: MLBr_00177

Alternate gene names: 221229468

Gene position: 244240-244785 (Clockwise)

Preceding gene: 221229467

Following gene: 221229472

Centisome position: 7.47

GC content: 59.16

Gene sequence:

>546_bases
GTGTTAGTCGATAAGCAATTGTCCGAGCTCGGATATACGGTTGCACCCATGGAGAAGGGTGTCGAGTTGGTAGTCGGACG
TGCACTTATTGTCGTTGTCGACGATCGCACCGCGCATGGGGATGAGGACCACAGCGGGCCGCTGGTCACTGAGCTGTTGA
CCGAGGCCGGGTTCGTCGTTGATGGTGTGGTGGCGGTGGCGGCTGACGAGGTCGAGATACGCAACGCGTTGAACACTGCA
GTGATCGGTGGGGTGGACCTAGTGGTCTCGGTCGGCGGAACCGGTGTTACACCACGTGACGTCGCTCCAGAGGCCACCCG
CGAGATTCTGGATCGGGAAATTCTAGGTATTGCCGAAGCCATCCGTGCTTCGGGGCTGTCCGCGGGAATCACCGACGCCG
GATTGTCGCGTGGTCTAGCTGGTGTTTCGGGCAGTACGTTGGTGGTAAACCTCGCCGGCTCCCGTTATGCGGTGCGCGAC
GGAATGGCTACATTGAATCCGCTGGCCACCCAGATCATTGGGCAATTATCGAGTCTGGAAATCTAG

Upstream 100 bases:

>100_bases
AAAGTGTCGCTGACCTATCAGGATCAGTCTGGTAGCAGTCGCACGGTTCAGGTCACACTCGGCAAGGCGGAACAGTAACA
ATTAATAATCGAGAGCTACC

Downstream 100 bases:

>100_bases
GCTGGCGCCGCTGCGGTCATGTGTCTGCGCGAGGTTCGTGGTTTGGGGTTGGCGTCAGATCGGCTGTATCGACGTGCCTG
CCGGACGGAGCCCCGTTACT

Product: putative molybdenum cofactor biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MLVDKQLSELGYTVAPMEKGVELVVGRALIVVVDDRTAHGDEDHSGPLVTELLTEAGFVVDGVVAVAADEVEIRNALNTA
VIGGVDLVVSVGGTGVTPRDVAPEATREILDREILGIAEAIRASGLSAGITDAGLSRGLAGVSGSTLVVNLAGSRYAVRD
GMATLNPLATQIIGQLSSLEI

Sequences:

>Translated_181_residues
MLVDKQLSELGYTVAPMEKGVELVVGRALIVVVDDRTAHGDEDHSGPLVTELLTEAGFVVDGVVAVAADEVEIRNALNTA
VIGGVDLVVSVGGTGVTPRDVAPEATREILDREILGIAEAIRASGLSAGITDAGLSRGLAGVSGSTLVVNLAGSRYAVRD
GMATLNPLATQIIGQLSSLEI
>Mature_181_residues
MLVDKQLSELGYTVAPMEKGVELVVGRALIVVVDDRTAHGDEDHSGPLVTELLTEAGFVVDGVVAVAADEVEIRNALNTA
VIGGVDLVVSVGGTGVTPRDVAPEATREILDREILGIAEAIRASGLSAGITDAGLSRGLAGVSGSTLVVNLAGSRYAVRD
GMATLNPLATQIIGQLSSLEI

Specific function: Maybe involved in the biosynthesis of molybdopterin [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=131, Percent_Identity=34.3511450381679, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI66932975, Length=131, Percent_Identity=34.3511450381679, Blast_Score=68, Evalue=6e-12,
Organism=Escherichia coli, GI1787000, Length=152, Percent_Identity=32.8947368421053, Blast_Score=60, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17564954, Length=163, Percent_Identity=34.9693251533742, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17136978, Length=144, Percent_Identity=34.7222222222222, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24638841, Length=144, Percent_Identity=34.7222222222222, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18481; Mature: 18481

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVDKQLSELGYTVAPMEKGVELVVGRALIVVVDDRTAHGDEDHSGPLVTELLTEAGFVV
CCCCHHHHHCCCEECCHHCCHHEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCHH
DGVVAVAADEVEIRNALNTAVIGGVDLVVSVGGTGVTPRDVAPEATREILDREILGIAEA
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IRASGLSAGITDAGLSRGLAGVSGSTLVVNLAGSRYAVRDGMATLNPLATQIIGQLSSLE
HHHCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCEEEHHCCCHHHHHHHHHHHHHHHHCC
I
C
>Mature Secondary Structure
MLVDKQLSELGYTVAPMEKGVELVVGRALIVVVDDRTAHGDEDHSGPLVTELLTEAGFVV
CCCCHHHHHCCCEECCHHCCHHEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCHH
DGVVAVAADEVEIRNALNTAVIGGVDLVVSVGGTGVTPRDVAPEATREILDREILGIAEA
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IRASGLSAGITDAGLSRGLAGVSGSTLVVNLAGSRYAVRDGMATLNPLATQIIGQLSSLE
HHHCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCEEEHHCCCHHHHHHHHHHHHHHHHCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]