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The map label for this gene is eccB1 [H]

Identifier: 221229382

GI number: 221229382

Start: 67413

End: 68858

Strand: Reverse

Name: eccB1 [H]

Synonym: MLBr_00054

Alternate gene names: 221229382

Gene position: 68858-67413 (Counterclockwise)

Preceding gene: 221229383

Following gene: 221229381

Centisome position: 2.11

GC content: 58.78

Gene sequence:

>1446_bases
ATGGGGCTTCGCCTGACCACCAAGGTTCAGGTCAGCGGCTGGCGCTTCCTGCTTCGCAGGGTTGAGCATGCCATCGTGCG
GCGCGACACTCGGATGTTCGACGACCCGCTGCAGTTCTACAGTCGCTCGATCGCCCTTGGCATCGTTGTTGCGGTTGCGC
TCCTGATAGGCGCCGTCCTGCTGGCGTACTTCAAACCACAGGGCAAGCTAGGTGCCAGCACCCTTCTGACCGATCGGGCA
ACCAATCAGCTCTACGTGCTCTTGTCCGGGCATCTGTATCCAGTGTACAACTTGACCTCGGCGCGACTGGCGCTGGGCAA
ACCGGCTAACCCAGCTGCCGTGAAGTCCAGCGAATTGACCAAGCTGCCTATAGGTCAGACCATCGGAATCCCTGGTGCAC
CCTACGCCACGCCTGTTTCAGGGGATTCCTCGTCAACCTGGACCTTGTGCGACACCGTCGCCAAGATCGAGAGCGAATCG
CCGGCGGTGCAGACTTCGGTTATAGCTCGATCACTACAGATCGACCCTGCGATAAATCCATTGCAACCGAACGAAGCGCT
ACTGGCGTCATACCGGGACAAAACGTGGCTAGTTAACTCAAAAGGGCGGCACTCCATCGATCTGGCCGACCGGGCCCTAA
CCTCGGCCATAGGAATATCGGTAAACGTTAAGCCAACCCCACTCTCTGAGGGCCTGTTCAACGCACTACCCGACGTCGGC
AGGTGGGAGCTGCCGACGATTCCTGACACTGGAGCACCTAATTCGCTGGGGTTATCCCCAGACCTCGTAATTGGGTCGGT
GTTCCAAATCCAAATGGAAAAGAGCCCACAGTACTACGTGGTACTCTCCGACGGCATCGCCCAGGTGAATGCCACCACCG
CTGATGCGTTGCGCGCTACCCAGTCGCATGGACTGGTAGCGCCTCCATCACTGGTACCAAACGTGGTCGTCCAGATTCCC
GAACGGGTCTACGACTCGCCACTGCCCGATGAACCACTCAAGATGGTGGCCCGGGACGACTACCCAACGCTGTGTTGGGC
ATGGGAACGCAAAGCCAGTGATCAGGCGCCGAAGAGAACCATGTTGATTGGTCAGCATCTGCCACTACAGCCGTCAGCCA
TGAGCACAGGTATAAAACAGATCCGTGGGACAGCAACCGTCTATATTGATGGTGGCAGATACGTGGCGCTACAGTCTCCA
GACCCCCGGTACAGTGAATCCCTGTACTACGTTGATCCGGAGGGAGTACGTTACGGCCTGGCGAACTCGGAGGCGGTGAA
GGCGCTGGGCCTCGCTTCACCGCAGACAGCGCCCTGGGTGATCGTTCGTCTTCTGGTGGAGGGGCCTGTGCTCTCCAGAG
ACGCAGCTCTGTTAGAGCACGATACGCTGATCGCGGACCCAAGCCCACGGAAAGTACCAGCCGGCTACTCTGGAGTGAGG
CCATGA

Upstream 100 bases:

>100_bases
CGAGCAACTGGATGTGGACCGACTGCAGGAGATCAACGGCTCAGACATGGCCGAGGCGATCGCCACGGTGCACGCACACC
TCAACATAAGAGAGTGAACC

Downstream 100 bases:

>100_bases
CGACGAAAAAGTTCACCCCGACTATCACCCGCGGACCGCGATTGACACCGGGCGAGATCAACATCACGCCGCCCGATGAC
CTCGGTCTTGAGATCCCACC

Product: hypothetical protein

Products: NA

Alternate protein names: ESX conserved component B1; Type VII secretion system protein eccB1; T7SS protein eccB1 [H]

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MGLRLTTKVQVSGWRFLLRRVEHAIVRRDTRMFDDPLQFYSRSIALGIVVAVALLIGAVLLAYFKPQGKLGASTLLTDRA
TNQLYVLLSGHLYPVYNLTSARLALGKPANPAAVKSSELTKLPIGQTIGIPGAPYATPVSGDSSSTWTLCDTVAKIESES
PAVQTSVIARSLQIDPAINPLQPNEALLASYRDKTWLVNSKGRHSIDLADRALTSAIGISVNVKPTPLSEGLFNALPDVG
RWELPTIPDTGAPNSLGLSPDLVIGSVFQIQMEKSPQYYVVLSDGIAQVNATTADALRATQSHGLVAPPSLVPNVVVQIP
ERVYDSPLPDEPLKMVARDDYPTLCWAWERKASDQAPKRTMLIGQHLPLQPSAMSTGIKQIRGTATVYIDGGRYVALQSP
DPRYSESLYYVDPEGVRYGLANSEAVKALGLASPQTAPWVIVRLLVEGPVLSRDAALLEHDTLIADPSPRKVPAGYSGVR
P

Sequences:

>Translated_481_residues
MGLRLTTKVQVSGWRFLLRRVEHAIVRRDTRMFDDPLQFYSRSIALGIVVAVALLIGAVLLAYFKPQGKLGASTLLTDRA
TNQLYVLLSGHLYPVYNLTSARLALGKPANPAAVKSSELTKLPIGQTIGIPGAPYATPVSGDSSSTWTLCDTVAKIESES
PAVQTSVIARSLQIDPAINPLQPNEALLASYRDKTWLVNSKGRHSIDLADRALTSAIGISVNVKPTPLSEGLFNALPDVG
RWELPTIPDTGAPNSLGLSPDLVIGSVFQIQMEKSPQYYVVLSDGIAQVNATTADALRATQSHGLVAPPSLVPNVVVQIP
ERVYDSPLPDEPLKMVARDDYPTLCWAWERKASDQAPKRTMLIGQHLPLQPSAMSTGIKQIRGTATVYIDGGRYVALQSP
DPRYSESLYYVDPEGVRYGLANSEAVKALGLASPQTAPWVIVRLLVEGPVLSRDAALLEHDTLIADPSPRKVPAGYSGVR
P
>Mature_480_residues
GLRLTTKVQVSGWRFLLRRVEHAIVRRDTRMFDDPLQFYSRSIALGIVVAVALLIGAVLLAYFKPQGKLGASTLLTDRAT
NQLYVLLSGHLYPVYNLTSARLALGKPANPAAVKSSELTKLPIGQTIGIPGAPYATPVSGDSSSTWTLCDTVAKIESESP
AVQTSVIARSLQIDPAINPLQPNEALLASYRDKTWLVNSKGRHSIDLADRALTSAIGISVNVKPTPLSEGLFNALPDVGR
WELPTIPDTGAPNSLGLSPDLVIGSVFQIQMEKSPQYYVVLSDGIAQVNATTADALRATQSHGLVAPPSLVPNVVVQIPE
RVYDSPLPDEPLKMVARDDYPTLCWAWERKASDQAPKRTMLIGQHLPLQPSAMSTGIKQIRGTATVYIDGGRYVALQSPD
PRYSESLYYVDPEGVRYGLANSEAVKALGLASPQTAPWVIVRLLVEGPVLSRDAALLEHDTLIADPSPRKVPAGYSGVRP

Specific function: Probably part of a complex that is involved in secretion of ESX-1 substrates, such as EsxA (ESAT-6) and EsxB (CFP-10) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eccB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007795 [H]

Pfam domain/function: PF05108 DUF690 [H]

EC number: NA

Molecular weight: Translated: 51875; Mature: 51744

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLRLTTKVQVSGWRFLLRRVEHAIVRRDTRMFDDPLQFYSRSIALGIVVAVALLIGAVL
CCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAYFKPQGKLGASTLLTDRATNQLYVLLSGHLYPVYNLTSARLALGKPANPAAVKSSELT
HHHHCCCCCCCCHHHEECCCCCEEEEEEECCEEEEEECCHHHEECCCCCCCCCCCCCCCE
KLPIGQTIGIPGAPYATPVSGDSSSTWTLCDTVAKIESESPAVQTSVIARSLQIDPAINP
ECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCCC
LQPNEALLASYRDKTWLVNSKGRHSIDLADRALTSAIGISVNVKPTPLSEGLFNALPDVG
CCCCHHHHHHCCCCEEEECCCCCCEEHHHHHHHHHHHCEEEECCCCCCHHHHHHHCCCCC
RWELPTIPDTGAPNSLGLSPDLVIGSVFQIQMEKSPQYYVVLSDGIAQVNATTADALRAT
CCCCCCCCCCCCCCCCCCCCCCEECEEEEEEEECCCCEEEEEECCCEEECCCHHHHHHHH
QSHGLVAPPSLVPNVVVQIPERVYDSPLPDEPLKMVARDDYPTLCWAWERKASDQAPKRT
HCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCHHHHHCCCCCCCEEEEECCCCCCCCCCEE
MLIGQHLPLQPSAMSTGIKQIRGTATVYIDGGRYVALQSPDPRYSESLYYVDPEGVRYGL
EEECCCCCCCCHHHHHHHHHHCCEEEEEEECCEEEEECCCCCCCCCCEEEECCCCCEECC
ANSEAVKALGLASPQTAPWVIVRLLVEGPVLSRDAALLEHDTLIADPSPRKVPAGYSGVR
CCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCEEEECCCCCCCCCCCCCCC
P
C
>Mature Secondary Structure 
GLRLTTKVQVSGWRFLLRRVEHAIVRRDTRMFDDPLQFYSRSIALGIVVAVALLIGAVL
CCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAYFKPQGKLGASTLLTDRATNQLYVLLSGHLYPVYNLTSARLALGKPANPAAVKSSELT
HHHHCCCCCCCCHHHEECCCCCEEEEEEECCEEEEEECCHHHEECCCCCCCCCCCCCCCE
KLPIGQTIGIPGAPYATPVSGDSSSTWTLCDTVAKIESESPAVQTSVIARSLQIDPAINP
ECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCCC
LQPNEALLASYRDKTWLVNSKGRHSIDLADRALTSAIGISVNVKPTPLSEGLFNALPDVG
CCCCHHHHHHCCCCEEEECCCCCCEEHHHHHHHHHHHCEEEECCCCCCHHHHHHHCCCCC
RWELPTIPDTGAPNSLGLSPDLVIGSVFQIQMEKSPQYYVVLSDGIAQVNATTADALRAT
CCCCCCCCCCCCCCCCCCCCCCEECEEEEEEEECCCCEEEEEECCCEEECCCHHHHHHHH
QSHGLVAPPSLVPNVVVQIPERVYDSPLPDEPLKMVARDDYPTLCWAWERKASDQAPKRT
HCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCHHHHHCCCCCCCEEEEECCCCCCCCCCEE
MLIGQHLPLQPSAMSTGIKQIRGTATVYIDGGRYVALQSPDPRYSESLYYVDPEGVRYGL
EEECCCCCCCCHHHHHHHHHHCCEEEEEEECCEEEEECCCCCCCCCCEEEECCCCCEECC
ANSEAVKALGLASPQTAPWVIVRLLVEGPVLSRDAALLEHDTLIADPSPRKVPAGYSGVR
CCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCEEEECCCCCCCCCCCCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]