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The map label for this gene is scrK [H]

Identifier: 220933100

GI number: 220933100

Start: 2475407

End: 2476351

Strand: Reverse

Name: scrK [H]

Synonym: Hore_22680

Alternate gene names: 220933100

Gene position: 2476351-2475407 (Counterclockwise)

Preceding gene: 220933101

Following gene: 220933098

Centisome position: 96.05

GC content: 42.96

Gene sequence:

>945_bases
ATGCCTGAAGTAATAACCATTGGTGAAGTCCTTGTTGAAGTAATGGCCAGGGAGATTAACCAGAAGTTTTCTGAGCCCGG
GGAGTTTGTCGGGCCATTTCCCAGCGGAGCTCCGGCCATATTTATTGATCAGGTCGCCAAAATGGGAGTTAGCTGTGGGA
TAATATCAAAAGTAGGTAATGATGATTTTGGATACCTCAACCAGAAAAGGCTTGAAAAGGATGGGGTTGATACCAGTTAT
CTCGCTGTTTCAGACGAACATACTACCGGTGTTGCTTTTGTTACCTATATGGATAATGGTGACCGGGAATTTATTTTTCA
CTTAAAAGAAGCCGCCCCTGGCTATATAAGTGAAGATGATATTGATGAAGGATACTTTGAAGATTGTAAATACCTTCATT
TGATGGGCTGTTCCCTATTTAATAAGTCTATACGAAAGGCCATAGGTAAAGCCCTGGACATAGCATCTGAAAAAGGGGTA
AGGATATCCTTTGACCCCAACGTCAGAAAGGAGCTCCTTCAGGATAAGGAGATTAAGGACCTGTTTGATAGAATCCTGGA
TCAGTGTTATATATTTTTACCCGGGGAAGAGGAGCTTAAGTTTGTAACCGGGTATGACAGAGAAGAAGAGGCCATTCAGT
ATTTAAGGAATAAAGGTGTTGAAATAATTGCTGTCAAAAAGGGTAGAAGGGGCAGTAAGGTTTATACTGATGAAGTTACG
TATACATTAAAACCCTTTAAGGTAGAGGAGGTTGATCCTACCGGGGCAGGGGATACATATGACGGGGCCTTGATAGCAAG
CCTGGTTAACGGGAAGGGGTTTGAAAAGGCCTTACGGTATGCCAGTGCTGCCGGGGCTCTTGCTGTAACTACAAAAGGTC
CCATGGAGGGGACCAGGACTGTTCCGGAATTAGATGAATTTATTAAATCACAACAGAAGATGTAA

Upstream 100 bases:

>100_bases
AGAAATAAATCAAATAGGTAAACAATATAAAAAAGAGAGAAACTTAAACAGGAAACTGATATTAAGAGATTCGGGAGAAC
ACCACTAGAGGGGGGTTTAC

Downstream 100 bases:

>100_bases
ACATATGAACTGTTATTCCAGAATTAAAAAAGGGCAGGAAGGAAAAACTCTCCACATTGGTTAAGGTACAACGGTTTAAA
GTCAGGTTAAGGGATAAGAG

Product: PfkB domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MPEVITIGEVLVEVMAREINQKFSEPGEFVGPFPSGAPAIFIDQVAKMGVSCGIISKVGNDDFGYLNQKRLEKDGVDTSY
LAVSDEHTTGVAFVTYMDNGDREFIFHLKEAAPGYISEDDIDEGYFEDCKYLHLMGCSLFNKSIRKAIGKALDIASEKGV
RISFDPNVRKELLQDKEIKDLFDRILDQCYIFLPGEEELKFVTGYDREEEAIQYLRNKGVEIIAVKKGRRGSKVYTDEVT
YTLKPFKVEEVDPTGAGDTYDGALIASLVNGKGFEKALRYASAAGALAVTTKGPMEGTRTVPELDEFIKSQQKM

Sequences:

>Translated_314_residues
MPEVITIGEVLVEVMAREINQKFSEPGEFVGPFPSGAPAIFIDQVAKMGVSCGIISKVGNDDFGYLNQKRLEKDGVDTSY
LAVSDEHTTGVAFVTYMDNGDREFIFHLKEAAPGYISEDDIDEGYFEDCKYLHLMGCSLFNKSIRKAIGKALDIASEKGV
RISFDPNVRKELLQDKEIKDLFDRILDQCYIFLPGEEELKFVTGYDREEEAIQYLRNKGVEIIAVKKGRRGSKVYTDEVT
YTLKPFKVEEVDPTGAGDTYDGALIASLVNGKGFEKALRYASAAGALAVTTKGPMEGTRTVPELDEFIKSQQKM
>Mature_313_residues
PEVITIGEVLVEVMAREINQKFSEPGEFVGPFPSGAPAIFIDQVAKMGVSCGIISKVGNDDFGYLNQKRLEKDGVDTSYL
AVSDEHTTGVAFVTYMDNGDREFIFHLKEAAPGYISEDDIDEGYFEDCKYLHLMGCSLFNKSIRKAIGKALDIASEKGVR
ISFDPNVRKELLQDKEIKDLFDRILDQCYIFLPGEEELKFVTGYDREEEAIQYLRNKGVEIIAVKKGRRGSKVYTDEVTY
TLKPFKVEEVDPTGAGDTYDGALIASLVNGKGFEKALRYASAAGALAVTTKGPMEGTRTVPELDEFIKSQQKM

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87081971, Length=322, Percent_Identity=23.9130434782609, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790193, Length=271, Percent_Identity=27.3062730627306, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87082281, Length=316, Percent_Identity=22.4683544303797, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=284, Percent_Identity=28.5211267605634, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.4 [H]

Molecular weight: Translated: 34885; Mature: 34754

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEVITIGEVLVEVMAREINQKFSEPGEFVGPFPSGAPAIFIDQVAKMGVSCGIISKVGN
CCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCC
DDFGYLNQKRLEKDGVDTSYLAVSDEHTTGVAFVTYMDNGDREFIFHLKEAAPGYISEDD
CCCCCCCHHHHHHCCCCCEEEEEECCCCCCEEEEEEEECCCCEEEEEEHHCCCCCCCCCC
IDEGYFEDCKYLHLMGCSLFNKSIRKAIGKALDIASEKGVRISFDPNVRKELLQDKEIKD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCHHHH
LFDRILDQCYIFLPGEEELKFVTGYDREEEAIQYLRNKGVEIIAVKKGRRGSKVYTDEVT
HHHHHHHHEEEECCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEECCEE
YTLKPFKVEEVDPTGAGDTYDGALIASLVNGKGFEKALRYASAAGALAVTTKGPMEGTRT
EEECCEEEECCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCCC
VPELDEFIKSQQKM
CHHHHHHHHHHCCC
>Mature Secondary Structure 
PEVITIGEVLVEVMAREINQKFSEPGEFVGPFPSGAPAIFIDQVAKMGVSCGIISKVGN
CCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCC
DDFGYLNQKRLEKDGVDTSYLAVSDEHTTGVAFVTYMDNGDREFIFHLKEAAPGYISEDD
CCCCCCCHHHHHHCCCCCEEEEEECCCCCCEEEEEEEECCCCEEEEEEHHCCCCCCCCCC
IDEGYFEDCKYLHLMGCSLFNKSIRKAIGKALDIASEKGVRISFDPNVRKELLQDKEIKD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCHHHH
LFDRILDQCYIFLPGEEELKFVTGYDREEEAIQYLRNKGVEIIAVKKGRRGSKVYTDEVT
HHHHHHHHEEEECCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEECCEE
YTLKPFKVEEVDPTGAGDTYDGALIASLVNGKGFEKALRYASAAGALAVTTKGPMEGTRT
EEECCEEEECCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCCC
VPELDEFIKSQQKM
CHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2174811 [H]