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The map label for this gene is cysC

Identifier: 220933097

GI number: 220933097

Start: 2470608

End: 2471165

Strand: Reverse

Name: cysC

Synonym: Hore_22650

Alternate gene names: 220933097

Gene position: 2471165-2470608 (Counterclockwise)

Preceding gene: 220933098

Following gene: 220933096

Centisome position: 95.85

GC content: 42.83

Gene sequence:

>558_bases
ATGCGAAATCAAAAGGGAGTAACTGTCTGGTTTACCGGTTTAAGCGGGGCCGGTAAAACCACTGTTGCCAGAGAAGTAGA
AAGGCAATTAAAAGAAAAAGGCTATTATGTCCAGAGGCTTGATGGTGATATTGTCCGTCAGCATTTAACCAGGGATTTAG
GATTTACCAAGGAAGACAGGGATGAAAACATCAGAAGAAACAGTTTTGTAGCTAAATTACTTACCCAGAATGATATCATT
ACCCTGTGTTCATTTATTTCGCCTTACCGTAAGGCCCGCCAGACAGCCAGGGAAATAATAGGTGAATTCATTGAGGTTTA
TGTTAATGCTCCCCTGGAAGTCTGTGAGGACAGGGATGTTAAAGGGCTGTATGCCAAAGCCAGGGCCGGGGAAATTGATA
ACTTTACAGGCATTTCCGATCCTTACGAACCACCACAAAATCCAGATCTGGAACTGAGGACCGACAAAGAAACTGTGGAA
GAAAGTGCGAGTAAGGTAATTGAATACCTTGAAGAGAAGGGTTATATAAATTTGCCTGAGGATGTTCTGGCAGGTTAA

Upstream 100 bases:

>100_bases
ATTTATAAACTTTTAATTATAGCCGGTTACATTGAATAACCGATTATGATCAATATAACTCAGTTAATTTAGAAAGGATT
TAATAAAGGAGGAAGTAATA

Downstream 100 bases:

>100_bases
TGTAGGCAAGACAACATAAAAAATAAAGGTGAGACCAGTATTAAAATAAAATAAATTATACACTAAAAAAAGAGGGGATA
TCCCCTCTTTTTTTTTATTG

Product: Adenylyl-sulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MRNQKGVTVWFTGLSGAGKTTVAREVERQLKEKGYYVQRLDGDIVRQHLTRDLGFTKEDRDENIRRNSFVAKLLTQNDII
TLCSFISPYRKARQTAREIIGEFIEVYVNAPLEVCEDRDVKGLYAKARAGEIDNFTGISDPYEPPQNPDLELRTDKETVE
ESASKVIEYLEEKGYINLPEDVLAG

Sequences:

>Translated_185_residues
MRNQKGVTVWFTGLSGAGKTTVAREVERQLKEKGYYVQRLDGDIVRQHLTRDLGFTKEDRDENIRRNSFVAKLLTQNDII
TLCSFISPYRKARQTAREIIGEFIEVYVNAPLEVCEDRDVKGLYAKARAGEIDNFTGISDPYEPPQNPDLELRTDKETVE
ESASKVIEYLEEKGYINLPEDVLAG
>Mature_185_residues
MRNQKGVTVWFTGLSGAGKTTVAREVERQLKEKGYYVQRLDGDIVRQHLTRDLGFTKEDRDENIRRNSFVAKLLTQNDII
TLCSFISPYRKARQTAREIIGEFIEVYVNAPLEVCEDRDVKGLYAKARAGEIDNFTGISDPYEPPQNPDLELRTDKETVE
ESASKVIEYLEEKGYINLPEDVLAG

Specific function: Catalyzes the synthesis of activated sulfate

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family

Homologues:

Organism=Homo sapiens, GI46094058, Length=173, Percent_Identity=52.0231213872832, Blast_Score=176, Evalue=1e-44,
Organism=Homo sapiens, GI62912492, Length=176, Percent_Identity=48.2954545454545, Blast_Score=169, Evalue=1e-42,
Organism=Homo sapiens, GI34447231, Length=176, Percent_Identity=48.2954545454545, Blast_Score=169, Evalue=1e-42,
Organism=Escherichia coli, GI1789107, Length=157, Percent_Identity=50.9554140127389, Blast_Score=164, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17542422, Length=182, Percent_Identity=50.5494505494505, Blast_Score=176, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6322852, Length=174, Percent_Identity=54.0229885057471, Blast_Score=184, Evalue=6e-48,
Organism=Drosophila melanogaster, GI24667040, Length=179, Percent_Identity=49.7206703910614, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24667032, Length=179, Percent_Identity=49.7206703910614, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24667028, Length=179, Percent_Identity=49.7206703910614, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24667036, Length=179, Percent_Identity=49.7206703910614, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI116007838, Length=179, Percent_Identity=49.7206703910614, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24667044, Length=179, Percent_Identity=49.7206703910614, Blast_Score=174, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSC_HALOH (B8D0S4)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002510005.1
- ProteinModelPortal:   B8D0S4
- SMR:   B8D0S4
- GeneID:   7313017
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_22650
- HOGENOM:   HBG309946
- OMA:   TVCESRD
- HAMAP:   MF_00065
- InterPro:   IPR002891
- TIGRFAMs:   TIGR00455

Pfam domain/function: PF01583 APS_kinase

EC number: =2.7.1.25

Molecular weight: Translated: 21106; Mature: 21106

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: ACT_SITE 87-87

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNQKGVTVWFTGLSGAGKTTVAREVERQLKEKGYYVQRLDGDIVRQHLTRDLGFTKEDR
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCCCCCH
DENIRRNSFVAKLLTQNDIITLCSFISPYRKARQTAREIIGEFIEVYVNAPLEVCEDRDV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCC
KGLYAKARAGEIDNFTGISDPYEPPQNPDLELRTDKETVEESASKVIEYLEEKGYINLPE
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCCH
DVLAG
HHHCC
>Mature Secondary Structure
MRNQKGVTVWFTGLSGAGKTTVAREVERQLKEKGYYVQRLDGDIVRQHLTRDLGFTKEDR
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCCCCCH
DENIRRNSFVAKLLTQNDIITLCSFISPYRKARQTAREIIGEFIEVYVNAPLEVCEDRDV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCC
KGLYAKARAGEIDNFTGISDPYEPPQNPDLELRTDKETVEESASKVIEYLEEKGYINLPE
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCCH
DVLAG
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA